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  1. Article ; Online: Supplemental Patch Testing Identifies Allergens Missed by Standard Screening Series.

    Atwater, Amber Reck / Liu, Beiyu / Walsh, Rabina / Bembry, Raina / Ward, Jordan Maxwell / Green, Cynthia L

    Dermatitis : contact, atopic, occupational, drug

    2024  

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-01-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2144723-8
    ISSN 2162-5220 ; 1532-8163 ; 1710-3568
    ISSN (online) 2162-5220 ; 1532-8163
    ISSN 1710-3568
    DOI 10.1089/derm.2023.0310
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Response to Commentaries: Sniffing Out Consensus on the Evolution of Primate Same-Sex Sexual Behavior.

    Pfau, Daniel R / Jordan, Cynthia L / Breedlove, S Marc

    Archives of sexual behavior

    2021  Volume 50, Issue 6, Page(s) 2317–2320

    MeSH term(s) Animals ; Consensus ; Humans ; Primates ; Sexual Behavior
    Language English
    Publishing date 2021-08-25
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 184221-3
    ISSN 1573-2800 ; 0004-0002
    ISSN (online) 1573-2800
    ISSN 0004-0002
    DOI 10.1007/s10508-021-02078-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Eating disorders, disordered eating, and body image research in New Zealand: a scoping review.

    Cleland, Lana / Kennedy, Hannah L / Pettie, Michaela A / Kennedy, Martin A / Bulik, Cynthia M / Jordan, Jennifer

    Journal of eating disorders

    2023  Volume 11, Issue 1, Page(s) 7

    Abstract: Background: The prevention and treatment of eating disorders relies on an extensive body of research that includes various foci and methodologies. This scoping review identified relevant studies of eating disorders, body image, and disordered eating ... ...

    Abstract Background: The prevention and treatment of eating disorders relies on an extensive body of research that includes various foci and methodologies. This scoping review identified relevant studies of eating disorders, body image, and disordered eating with New Zealand samples; charted the methodologies, sample characteristics, and findings reported; and identified several gaps that should be addressed by further research.
    Methods: Using scoping review methodology, two databases were searched for studies examining eating disorders, disordered eating, or body image with New Zealand samples. Snowball methods were further used to identify additional relevant articles that did not appear in initial searches. Two independent reviewers screened the titles and abstracts of 473 records. Full text assessment of the remaining 251 records resulted in 148 peer-reviewed articles being identified as eligible for the final review. A search of institutional databases yielded 106 Masters and Doctoral theses for assessment, with a total of 47 theses being identified as eligible for the final review. The included studies were classified by methodology, and the extracted information included the study foci, data collected, sample size, demographic information, and key findings.
    Results: The eligible studies examined a variety of eating disorder categories including binge-eating disorder, bulimia nervosa, and anorexia nervosa, in addition to disordered eating behaviours and body image in nonclinical or community samples. Methodologies included treatment trials, secondary analysis of existing datasets, non-treatment experimental interventions, cross-sectional observation, case-control studies, qualitative and mixed-methods studies, and case studies or series. Across all of the studies, questionnaire and interview data were most commonly utilised. A wide range of sample sizes were evident, and studies often reported all-female or mostly-female participants, with minimal inclusion of males and gender minorities. There was also an underrepresentation of minority ethnicities in many studies, highlighting the need for future research to increase diversity within samples.
    Conclusion: This study provides a comprehensive and detailed overview of research into eating disorders and body image in New Zealand, while highlighting important considerations for both local and international research.
    Language English
    Publishing date 2023-01-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2699357-0
    ISSN 2050-2974
    ISSN 2050-2974
    DOI 10.1186/s40337-022-00728-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Loss of TRPC2 function in mice alters sex differences in brain regions regulating social behaviors.

    Pfau, Daniel R / Baribeau, Sarah / Brown, Felix / Khetarpal, Niki / Marc Breedlove, S / Jordan, Cynthia L

    The Journal of comparative neurology

    2023  Volume 531, Issue 15, Page(s) 1550–1561

    Abstract: The transient receptor potential cation channel 2 (TRPC2) conveys pheromonal information from the vomeronasal organ (VNO) to the brain. Both male and female mice lacking this gene show altered sex-typical behavior as adults. We asked whether TRPC2, ... ...

    Abstract The transient receptor potential cation channel 2 (TRPC2) conveys pheromonal information from the vomeronasal organ (VNO) to the brain. Both male and female mice lacking this gene show altered sex-typical behavior as adults. We asked whether TRPC2, highly expressed in the VNO, normally participates in the development of VNO-recipient brain regions controlling mounting and aggression, two behaviors affected by TRPC2 loss. We now report significant effects of TRPC2 loss in both the posterodorsal aspect of the medial amygdala (MePD) and ventromedial nucleus of the hypothalamus (VMH) of male and female mice. In the MePD, a sex difference in neuron number was eliminated by the TRPC2 knockout (KO), but the effect was complex, with fewer neurons in the right MePD of females, and fewer neurons in the left MePD of males. In contrast, MePD astrocytes were unaffected by the KO. In the ventrolateral (vl) aspect of the VMH, KO females were like wildtype (WT) females, but TRPC2 loss had a dramatic effect in males, with fewer neurons than WT males and a smaller VMHvl overall. We also discovered a glial sex difference in VMHvl of WTs, with females having more astrocytes than males. Interestingly, TRPC2 loss increased astrocyte number in males in this region. We conclude that TRPC2 normally participates in the sexual differentiation of the mouse MePD and VMHvl. These changes in two key VNO-recipient regions may underlie the effects of the TRPC2 KO on behavior.
    MeSH term(s) Animals ; Female ; Male ; Mice ; Aggression/physiology ; Hypothalamus ; Neuroglia ; Sex Characteristics ; Social Behavior
    Chemical Substances Trpc2 protein, mouse
    Language English
    Publishing date 2023-07-27
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 3086-7
    ISSN 1096-9861 ; 0021-9967 ; 0092-7317
    ISSN (online) 1096-9861
    ISSN 0021-9967 ; 0092-7317
    DOI 10.1002/cne.25528
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Avoidant/restrictive food intake disorder (ARFID) in New Zealand and Australia: a scoping review.

    Kennedy, Hannah L / Hitchman, Leonie M / Pettie, Michaela A / Bulik, Cynthia M / Jordan, Jennifer

    Journal of eating disorders

    2023  Volume 11, Issue 1, Page(s) 196

    Abstract: Background: Avoidant/restrictive food intake disorder (ARFID) is an eating disorder that involves restrictive or avoidant eating behaviour not related to weight or body image concerns. It was first included in the Diagnostic and Statistical Manual of ... ...

    Abstract Background: Avoidant/restrictive food intake disorder (ARFID) is an eating disorder that involves restrictive or avoidant eating behaviour not related to weight or body image concerns. It was first included in the Diagnostic and Statistical Manual of Mental Disorders-fifth edition (DSM-5) in 2013. ARFID frequently begins in childhood and can have serious psychosocial impacts and detrimental health consequences when nutritional and energy needs are persistently unmet. This systematic scoping review focuses on Australasia, synthesizing the current literature landscape on ARFID, and offering recommendations for targeted, actionable research directions for both funders and researchers.
    Methods: Online databases and university thesis repositories were systematically searched for studies examining ARFID in the New Zealand or Australian population since 2013. Database search results were exported to Rayyan software, and two independent reviewers screened all identified sources, prior to extraction of key data.
    Results: Twenty-nine studies and one thesis from 138 screened sources were eligible for inclusion. Frequent study types were treatment interventions and cross-sectional studies, with populations including individuals with ARFID, ED service populations, parents/caregivers, health professionals, and non-clinical populations. ARFID presents in a range of settings and is associated with poorer quality of life and significant functional impairment. Assessment of ARFID was varied, and no specific treatment guidelines for ARFID have been written as yet.
    Conclusion: This review calls for more accurate prevalence estimates of ARFID in children and larger-scale studies in all ages using validated measures. It emphasizes the need for education and training of healthcare professionals, and interdisciplinary collaboration. Established interventions like behaviour analytics should be considered, and more comprehensive research is needed on interventions for ARFID, including controlled trials and longitudinal studies. Urgent research is needed to improve outcomes for those affected by ARFID.
    Language English
    Publishing date 2023-11-06
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2699357-0
    ISSN 2050-2974
    ISSN 2050-2974
    DOI 10.1186/s40337-023-00922-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: A Mirrored System of Health for the Uninsured: North Carolina's Independent Primary Care Safety Net.

    Jordan, Randolph S / Jones, Cynthia L / Gallagher, Timothy J

    North Carolina medical journal

    2020  Volume 81, Issue 2, Page(s) 141

    MeSH term(s) Health Services Accessibility ; Humans ; Medically Uninsured ; North Carolina ; Primary Health Care/organization & administration ; Safety-net Providers/organization & administration
    Language English
    Publishing date 2020-03-04
    Publishing country United States
    Document type Letter
    ZDB-ID 422795-5
    ISSN 0029-2559
    ISSN 0029-2559
    DOI 10.18043/ncm.81.2.141
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Testosterone works through androgen receptors to modulate neuronal response to anxiogenic stimuli.

    Chen, Chieh V / Jordan, Cynthia L / Breedlove, S Marc

    Neuroscience letters

    2021  Volume 753, Page(s) 135852

    Abstract: Testosterone (T) exerts anxiolytic effects through functional androgen receptors (ARs) in rodents. T treatment of castrated mice reduces anxiety-like behavior in wild-type (WT) males, but not males with a spontaneous mutation that renders AR ... ...

    Abstract Testosterone (T) exerts anxiolytic effects through functional androgen receptors (ARs) in rodents. T treatment of castrated mice reduces anxiety-like behavior in wild-type (WT) males, but not males with a spontaneous mutation that renders AR dysfunctional (testicular feminization mutation, Tfm). Using Cre-LoxP technology we created males carrying induced dysfunctional AR allele (induced TFM; iTfm) to determine the brain regions responsible for T-induced anxiolysis. Adult WT and iTfm mice were castrated and T treated. Castrated WTs given a blank capsule (WT + B) served as additional controls. Mice were later exposed to the anxiogenic light/dark box, sacrificed and their brains processed for immediate early gene cFos immunoreactivity. Analyses revealed that T treatment increased cFos-expressing neurons in the basolateral amygdala (blAMY) of WT males, but not in iTfm males, which did not differ from WT + B mice. In contrast, WT + T males displayed fewer cFos + cells than iTfm + T or WT + B groups in the suprachiasmatic nucleus of the hypothalamus (SCN). No effects of genotype or hormone were seen in cFos expression in the hippocampus, medial prefrontal cortex, paraventricular nucleus of the hypothalamus, oval and anterodorsal bed nucleus of the stria terminalis, or dorsal periaqueductal grey. AR immunohistochemistry indicated that ∼65 % of cells in the blAMY and SCN were AR + in WT males, so AR could act directly within neurons in these regions to modulate the animals' response to anxiogenic stimuli. Because absence of a functional AR did not affect cFos response to mild stress in the other brain regions, they are unlikely to mediate androgen's anxiolytic effects.
    MeSH term(s) Animals ; Anxiety/genetics ; Anxiety/pathology ; Basolateral Nuclear Complex/metabolism ; Basolateral Nuclear Complex/pathology ; Behavior, Animal ; Disease Models, Animal ; Female ; Humans ; Loss of Function Mutation ; Male ; Mice ; Mice, Transgenic ; Receptors, Androgen/genetics ; Receptors, Androgen/metabolism ; Sex Factors ; Suprachiasmatic Nucleus/metabolism ; Suprachiasmatic Nucleus/pathology ; Testosterone/metabolism
    Chemical Substances AR protein, mouse ; Receptors, Androgen ; Testosterone (3XMK78S47O)
    Language English
    Publishing date 2021-03-27
    Publishing country Ireland
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 194929-9
    ISSN 1872-7972 ; 0304-3940
    ISSN (online) 1872-7972
    ISSN 0304-3940
    DOI 10.1016/j.neulet.2021.135852
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: How genetic analysis may contribute to the understanding of avoidant/restrictive food intake disorder (ARFID).

    Kennedy, Hannah L / Dinkler, Lisa / Kennedy, Martin A / Bulik, Cynthia M / Jordan, Jennifer

    Journal of eating disorders

    2022  Volume 10, Issue 1, Page(s) 53

    Abstract: Avoidant/restrictive food intake disorder (ARFID) was introduced in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Unlike anorexia nervosa, ARFID is characterised by avoidant or restricted food intake that is not ... ...

    Abstract Avoidant/restrictive food intake disorder (ARFID) was introduced in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Unlike anorexia nervosa, ARFID is characterised by avoidant or restricted food intake that is not driven by weight or body shape-related concerns. As with other eating disorders, it is expected that ARFID will have a significant genetic risk component; however, sufficiently large-scale genetic investigations are yet to be performed in this group of patients. This narrative review considers the current literature on the diagnosis, presentation, and course of ARFID, including evidence for different presentations, and identifies fundamental questions about how ARFID might fit into the fluid landscape of other eating and mental disorders. In the absence of large ARFID GWAS, we consider genetic research on related conditions to point to possible features or mechanisms relevant to future ARFID investigations, and discuss the theoretical and clinical implications an ARFID GWAS. An argument for a collaborative approach to recruit ARFID participants for genome-wide association study is presented, as understanding the underlying genomic architecture of ARFID will be a key step in clarifying the biological mechanisms involved, and the development of interventions and treatments for this serious, and often debilitating disorder.
    Language English
    Publishing date 2022-04-15
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2699357-0
    ISSN 2050-2974
    ISSN 2050-2974
    DOI 10.1186/s40337-022-00578-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Consequences of cesarean delivery for neural development.

    Swift-Gallant, Ashlyn / Jordan, Cynthia L / Breedlove, S Marc

    Proceedings of the National Academy of Sciences of the United States of America

    2018  Volume 115, Issue 46, Page(s) 11664–11666

    MeSH term(s) Animals ; Brain ; Cell Death ; Cesarean Section ; Female ; Mice ; Neurogenesis ; Parturition ; Pregnancy
    Language English
    Publishing date 2018-10-29
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.1816335115
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A Large Segmental Mid-Diaphyseal Femoral Defect Sheep Model: Surgical Technique.

    Margolis, David S / Figueroa, Gerardo / Barron Villalobos, Efren / Smith, Jordan L / Doane, Cynthia J / Gonzales, David A / Szivek, John A

    Journal of investigative surgery : the official journal of the Academy of Surgical Research

    2022  Volume 35, Issue 6, Page(s) 1287–1295

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Animals ; Bone Plates ; External Fixators ; Femur/surgery ; Fracture Healing ; Humans ; Sheep ; Tibia/surgery ; Tibial Fractures/surgery
    Language English
    Publishing date 2022-03-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639444-9
    ISSN 1521-0553 ; 0894-1939
    ISSN (online) 1521-0553
    ISSN 0894-1939
    DOI 10.1080/08941939.2022.2045393
    Database MEDical Literature Analysis and Retrieval System OnLINE

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