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Article ; Online: Pan-Genomic and Transcriptomic Analyses of Marine Pseudoalteromonas agarivorans Hao 2018 Revealed Its Genomic and Metabolic Features

Yuhao Jv / Chenxiang Xi / Yanqiu Zhao / Wei Wang / Yiling Zhang / Kai Liu / Wenlin Liu / Kai Shan / Chunlei Wang / Ruiwen Cao / Cunxi Dai / Yiting Jv / Wenxing Zhu / Haiyong Wang / Qiuxia He / Lujiang Hao

Marine Drugs, Vol 20, Iss 248, p

2022 Volume 248

Abstract: The genomic and carbohydrate metabolic features of Pseudoalteromonas agarivorans Hao 2018 ( P ... agarivorans Hao 2018) were investigated through pan-genomic and transcriptomic analyses, and key enzyme genes ... with the stationary phase (24 h), strain P. agarivorans Hao 2018 had upregulated expression of genes related ...

Abstract	The genomic and carbohydrate metabolic features of Pseudoalteromonas agarivorans Hao 2018 ( P. agarivorans Hao 2018) were investigated through pan-genomic and transcriptomic analyses, and key enzyme genes that may encode the process involved in its extracellular polysaccharide synthesis were screened. The pan-genome of the P. agarivorans strains consists of a core-genome containing 2331 genes, an accessory-genome containing 956 genes, and a unique-genome containing 1519 genes. Clusters of Orthologous Groups analyses showed that P. agarivorans harbors strain-specifically diverse metabolisms, probably representing high evolutionary genome changes. The Kyoto Encyclopedia of Genes and Genomes and reconstructed carbohydrate metabolic pathways displayed that P. agarivorans strains can utilize a variety of carbohydrates, such as d -glucose, d -fructose, and d -lactose. Analyses of differentially expressed genes showed that compared with the stationary phase (24 h), strain P. agarivorans Hao 2018 had upregulated expression of genes related to the synthesis of extracellular polysaccharides in the logarithmic growth phase (2 h), and that the expression of these genes affected extracellular polysaccharide transport, nucleotide sugar synthesis, and glycosyltransferase synthesis. This is the first investigation of the genomic and metabolic features of P. agarivorans through pan-genomic and transcriptomic analyses, and these intriguing discoveries provide the possibility to produce novel marine drug lead compounds with high biological activity.
Keywords	Pseudoalteromonas agarivorans ; pan-genome ; genomic and metabolic features ; KEGG analysis ; transcriptome analysis ; Biology (General) ; QH301-705.5
Subject code	570
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Lectotypifications and Nomenclatural Notes for Hao′s New Chinese Taxa in Salix (Salicaceae)

He, Li / Applequist, Wendy L

Novon. 2020 Aug. 18, v. 28, no. 3

2020

Abstract: ... Skvortsov validated or intended to validate in 1998 following their original publication by Hao in 1936 ... for which a choice between syntypes was necessary: Salix acuminatomicrophylla K. S. Hao ex C. F. Fang & A. K ... Skvortsov, S. atopantha C. K. Schneid. var. glabra K. S. Hao ex C. F. Fang & A. K. Skvortsov, S. calyculata ...

Abstract	This paper deals with 20 names of species and infraspecific taxa of Salix L. that Fang and Skvortsov validated or intended to validate in 1998 following their original publication by Hao in 1936 without Latin diagnoses. The names are listed and issues of typification, attribution, and synonymy are discussed. New lectotypes are designated for eight names whose holotypes have been lost or destroyed or for which a choice between syntypes was necessary: Salix acuminatomicrophylla K. S. Hao ex C. F. Fang & A. K. Skvortsov, S. atopantha C. K. Schneid. var. glabra K. S. Hao ex C. F. Fang & A. K. Skvortsov, S. calyculata Hook. f. ex Andersson var. glabrifolia Hand.-Mazz. [≡ S. crenata K. S. Hao], S. forrestii K. S. Hao ex C. F. Fang & A. K. Skvortsov, S. kansuensis K. S. Hao ex C. F. Fang & A. K. Skvortsov, S. ovatomicrophylla K. S. Hao ex C. F. Fang & A. K. Skvortsov, S. pseudowolohoensis K. S. Hao ex C. F. Fang & A. K. Skvortsov, and S. schneideriana K. S. Hao ex C. F. Fang & A. K. Skvortsov. The type citation of S. shansiensis K. S. Hao ex C. F. Fang & A. K. Skvortsov is corrected.
Keywords	Salix ; holotypes ; lectotypes ; paper
Language	English
Dates of publication	2020-0818
Size	p. 180-185.
Publishing place	the Missouri Botanical Garden
Document type	Article
Note	NAL-light
ZDB-ID	2239681-0
ISSN	1055-3177
ISSN	1055-3177
DOI	10.3417/2020602
Database	NAL-Catalogue (AGRICOLA)

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Article: N2O Emission and Hydroxylamine Oxidase (HAO) Activity in a Nitrogen Removal Process Based on Activated Sludge with Three COD/NH4+ Ratios

He, Zhi‐xian / Yuan, Lin‐jiang / Wei, Yi‐ni / Nan, Ya‐ping

Water environment research. 2017 May, v. 89, no. 5

2017

Abstract: This study dealt with nitrous oxide (N₂O) emission and hydroxylamine oxidase (HAO) activity ... at two other C/N ratios (3.5, 6.5). The HAO activity in the anoxic period was higher with all three C/N ... anoxic conditions was affected by the HAO activity and vice versa. When the HAO activity was relatively high, it was ...

Abstract	This study dealt with nitrous oxide (N₂O) emission and hydroxylamine oxidase (HAO) activity of waste sludge in a nitrification and denitrification process employing three carbon nitrogen (C/N) ratios in a sequencing batch reactor (SBR). The experimental results indicated that N₂O emission increased dramatically after the C/N ratio in the sludge increased from 6.5 to 9.3, which was greater than the N₂O emission at two other C/N ratios (3.5, 6.5). The HAO activity in the anoxic period was higher with all three C/N ratios than in the aerobic period. The results suggest that N₂O was produced primarily in the aerobic period and the main source of the N₂O emission resulted from denitrification by nitrifying bacteria and aerobic hydroxylamine oxidation. When a relatively deficient carbon source existed, the N₂O emission under anoxic conditions was affected by the HAO activity and vice versa. When the HAO activity was relatively high, it was found that more N₂O was released.
Keywords	activated sludge ; batch systems ; carbon ; denitrification ; hydroxylamine ; nitrification ; nitrogen ; nitrous oxide ; nitrous oxide production ; oxidation ; oxidoreductases ; research ; water
Language	English
Dates of publication	2017-05
Size	p. 387-395.
Publishing place	Water Environment Federation
Document type	Article
Note	JOURNAL ARTICLE
ZDB-ID	1098976-6
ISSN	1554-7531 ; 1047-7624 ; 1061-4303
ISSN (online)	1554-7531
ISSN	1047-7624 ; 1061-4303
DOI	10.2175/106143017X14839994523668
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: A strategy for detecting optimal ratio of cardioprotection-dependent three compounds as quality control of guan-xin-er-hao formula.

Wang, Yang / Huang, Xi / Qin, Feng / Ren, Ping / Zhu, Zhengyan / Fan, Rong / Zhang, Chunhu / Zhang, Hainan / Tang, Tao / He, Juan / Liu, Zhaoqian / Zhou, Honghao

Journal of ethnopharmacology

2010 Volume 133, Issue 2, Page(s) 735–742

Abstract: ... ABCs) as quality control of guan-xin-er-hao (GXEH) formula extracted by various processings.: Methods ...

Abstract	Aims: We aimed to detect optimal ratio of cardioprotection-dependent absorbed bioactive compounds (ABCs) as quality control of guan-xin-er-hao (GXEH) formula extracted by various processings. Methods: Ferulic acid (F), tanshinol (T), hydroxysafflor yellow A (A), protocatechualdehyde (P) and paeoniflorin (E) in GXEH formula and FTA in blood from rat with acute myocardial infarction (AMI) were first identified by HPLC-MS/MS, and FTAPE in GXEH formulae with various herbs, extraction times and extraction water volumes were then quantitated only by HPLC. Results: FTAPE in various GXEH were determined. FTA were selected as GXEH's ABCs. Ratios of FTA were determined, suggesting the high (1:6.1:15.6), medium (1:1.7:15.2) and low (1:0.2:15.3) ratios. Three FTA ratios and their parent formulae ratio-dependently reduced infarct size, myocardial apoptosis and caspase-3 activity. Conclusion: There is the optimal ratio of F:T:A among various formulae, contributing to the best cardioprotection. This FTA ratio was developed as quality control of GXEH formula.
MeSH term(s)	Animals ; Apoptosis/drug effects ; Benzaldehydes/administration & dosage ; Benzoates/administration & dosage ; Bridged-Ring Compounds/administration & dosage ; Cardiotonic Agents/administration & dosage ; Cardiotonic Agents/chemistry ; Cardiotonic Agents/standards ; Caspase 3/metabolism ; Catechols/administration & dosage ; Chalcone/administration & dosage ; Chalcone/analogs & derivatives ; Chemistry, Pharmaceutical ; Coumaric Acids/administration & dosage ; Drugs, Chinese Herbal/administration & dosage ; Drugs, Chinese Herbal/chemistry ; Drugs, Chinese Herbal/pharmacokinetics ; Drugs, Chinese Herbal/standards ; Ethnopharmacology ; Glucosides/administration & dosage ; Male ; Monoterpenes ; Myocardial Infarction/drug therapy ; Myocardial Infarction/metabolism ; Myocardial Infarction/pathology ; Phytotherapy ; Quality Control ; Quinones/administration & dosage ; Rats ; Rats, Sprague-Dawley
Chemical Substances	Benzaldehydes ; Benzoates ; Bridged-Ring Compounds ; Cardiotonic Agents ; Catechols ; Coumaric Acids ; Drugs, Chinese Herbal ; Glucosides ; Monoterpenes ; Quinones ; guan xin II ; hydroxysafflor yellow A (146087-19-6) ; peoniflorin (21AIQ4EV64) ; protocatechualdehyde (4PVP2HCH4T) ; Chalcone (5S5A2Q39HX) ; ferulic acid (AVM951ZWST) ; Casp3 protein, rat (EC 3.4.22.-) ; Caspase 3 (EC 3.4.22.-)
Language	English
Publishing date	2010-11-10
Publishing country	Ireland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2010.11.006
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Article: A strategy for detecting optimal ratio of cardioprotection-dependent three compounds as quality control of Guan-Xin-Er-Hao formula

Wang, Yang / Huang, Xi / Qin, Feng / Ren, Ping / Zhu, Zhengyan / Fan, Rong / Zhang, Chunhu / Zhang, Hainan / Tang, Tao / He, Juan / Liu, Zhaoqian / Zhou, Honghao

Journal of ethnopharmacology. 2011 Jan. 27, v. 133, no. 2

2011

Abstract: ... ABCs) as quality control of Guan-Xin-Er-Hao (GXEH) formula extracted by various processings. Methods ...

Abstract	Aims: We aimed to detect optimal ratio of cardioprotection-dependent absorbed bioactive compounds (ABCs) as quality control of Guan-Xin-Er-Hao (GXEH) formula extracted by various processings. Methods: Ferulic acid (F), tanshinol (T), hydroxysafflor yellow A (A), protocatechualdehyde (P) and paeoniflorin (E) in GXEH formula and FTA in blood from rat with acute myocardial infarction (AMI) were first identified by HPLC-MS/MS, and FTAPE in GXEH formulae with various herbs, extraction times and extraction water volumes were then quantitated only by HPLC. Results: FTAPE in various GXEH were determined. FTA were selected as GXEH's ABCs. Ratios of FTA were determined, suggesting the high (1:6.1:15.6), medium (1:1.7:15.2) and low (1:0.2:15.3) ratios. Three FTA ratios and their parent formulae ratio-dependently reduced infarct size, myocardial apoptosis and caspase-3 activity. Conclusion: There is the optimal ratio of F:T:A among various formulae, contributing to the best cardioprotection. This FTA ratio was developed as quality control of GXEH formula.
Keywords	apoptosis ; bioactive properties ; blood ; caspase-3 ; ferulic acid ; herbs ; high performance liquid chromatography ; infarction ; myocardial infarction ; quality control ; rats
Language	English
Dates of publication	2011-0127
Size	p. 735-742.
Publishing place	Amsterdam; New York: Elsevier
Document type	Article
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2010.11.006
Database	NAL-Catalogue (AGRICOLA)

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Book ; Online: Biomechanics-Based Motion Analysis

Ma, Christina Zong-Hao / Li, Zhengrong / He, Chen / He, Chen

2023

Keywords	Medicine ; human ankle model ; product of exponentials formula ; anthropometry ; biomechanics ; coordinate measuring machines ; kinematics ; pose estimation ; position measurement ; biomedical informatics ; adolescent idiopathic scoliosis (AIS) ; surface electromyography (sEMG) ; paraspinal muscle ; Schroth exercise ; paraspinal muscle symmetry index (PMSI) ; negative heel shoes ; positive heel shoes ; gait ; pregnant women ; OpenSim ; IDEEA ; dentistry ; dental unit chair systems ; muscle fatigue ; muscle activation ; in vivo study ; femoral neck fracture ; internal fixation ; intramedullary fixation ; finite element analysis ; finite element ; proximal junctional failure ; spinal reconstruction ; thoracolumbar ; rollback ; ligament strain ; kinematic alignment ; mechanical alignment ; total knee arthroplasty ; markerless motion capture system ; gait analysis ; joint moment ; joint power ; running economy ; running style ; duty factor ; vertical oscillation ; stride frequency ; freezing of gait ; gait initiation ; Parkinson's disease ; posture ; segmental centers of mass ; anthropometric measurement ; base of support ; hand exoskeleton design ; motion simulation ; rehabilitation ; intention recognition ; machine learning ; deep learning ; two-dimensional (2D) image ; marker-free video ; walking speed ; walking speed classification ; bi-LSTM ; redundant feature ; ratio-based body measurement ; optimal feature ; surface topography ; rasterstereographic back shape analysis ; normative data ; healthy adults ; posture analysis ; spine ; intelligent system ; classroom behavior ; motion identification ; shoulder activity ; sensor ; rehabilitation protocol ; proximal humerus fracture ; ground reaction force ; knee and hip ; lower limb ; normal walking ; musculoskeletal multibody dynamics ; spinal biomechanics ; spinal alignment ; spinal loading ; muscle force computation ; thoracolumbar spine ; biomechanical model ; electromyography ; inertial measurement units ; gait-phase prediction ; spinal cord injury (SCI) ; muscle fiber conduction velocity (MFCV) ; surface electromyography (EMG) ; EMG-force relation ; composite index ; characteristic points ; multivariable linear regression ; anterior cruciate ligament deficiency ; competitive swimming ; performance ; velocity fluctuations ; multibody simulation ; finite element method ; co-simulation ; sports ; degeneration ; intervertebral disc ; coupled ; embryo implantation ; human choriocarcinoma cell ; extracellular matrix ; stiffness ; durotaxis ; n/a
Language	English
Size	1 electronic resource (386 pages)
Publisher	MDPI - Multidisciplinary Digital Publishing Institute
Publishing place	Basel
Document type	Book ; Online
Note	English
HBZ-ID	HT030382315
ISBN	9783036580265 ; 3036580263
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Book: Shi ming bie hao suo yin

Chen, Naiqian / Ding, Ning / He, Wen'guang / Lei, Mengshui

1982

Author's details	Chen nai qian bian; ding ning, he wen guang, lei meng shui bu bian
Keywords	Anonyms and pseudonyms, Chinese ; House names ; Names, Personal/Chinese
Language	Chinese
Size	18, 241, 17 p, 27 cm
Edition	Zeng ding ben, di 2 ban
Publisher	Zhong hua shu ju
Publishing place	Bei jing
Document type	Book
Note	Includes indexes
Database	Former special subject collection: coastal and deep sea fishing

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Article ; Online: Contextual bias in forensic toxicology decisions: A follow-up empirical study from China.

He, Ning / Hao, Hongxia

Journal of forensic sciences

2024

Abstract: The impact of contextual bias has been demonstrated repeatedly across forensic domains; however, research on this topic in forensic toxicology is very limited. In our previous study, experimental data from only one context version were compared with the ... ...

Abstract	The impact of contextual bias has been demonstrated repeatedly across forensic domains; however, research on this topic in forensic toxicology is very limited. In our previous study, experimental data from only one context version were compared with the actual forensic biasing casework. As a follow-up, this controlled experiment with 159 forensic toxicology practitioners was conducted, to test whether knowledge of different contextual information influenced their forensic decision-making. Participants in different context groups were tasked to identify testing strategies for carbon monoxide and opiate drugs. The results of chi-squared tests for their selections and two context groups exhibited statistically significant differences (p < 0.05 or p < 0.01). These findings show contextual information can bias forensic toxicology decisions about testing strategies, despite it is a relatively objective domain in forensic science.
Language	English
Publishing date	2024-04-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	219216-0
ISSN	1556-4029 ; 0022-1198
ISSN (online)	1556-4029
ISSN	0022-1198
DOI	10.1111/1556-4029.15520
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Article ; Online: Analysis of Ecological Environment Problems and Countermeasures in Ideological and Political Education in Colleges and Universities.

Hao, He

publication RETRACTED

Journal of environmental and public health

2022 Volume 2022, Page(s) 9479881

Abstract: At present, there are many problems in the mode and method of ideological and emotional education of college students. The state attaches great importance to this aspect and continues to increase investment, but the effect is not satisfactory. As an ... ...

Abstract	At present, there are many problems in the mode and method of ideological and emotional education of college students. The state attaches great importance to this aspect and continues to increase investment, but the effect is not satisfactory. As an important field for cultivating high-level socialist talents, colleges and universities have played a huge role in promoting the ideological development and emotional education of college students. The emergence of this contradiction shows that traditional educational methods have their own shortcomings and need to expand their thinking and explore new research areas. Since the new era, the ideological education venues and teaching activities of colleges and universities have been greatly improved, but they are also facing many problems and challenges, which seriously affect the moral quality of college students and destroy the ideological education ecosystem of colleges and universities. From the perspective of the ecological crisis of education, this paper awakens and pays attention to the ecological problems of education, making it an inevitable trend of current education development and paving the way for future research. On this basis, the current situation of the ecology of political education of college students is analyzed, and the necessity of research is proposed. Analyzing the ideological and emotional education of college students from the perspective of ecology is essentially to regard the ideological education of college students as an ecosystem and deeply analyze the distribution of various components and elements of college students' ideological and political education. The ecology of college students' ideological education is the process, law, and overall ecological balance of various factors in the ideological education system of college students, as well as the methodological thinking and value orientation of the interaction between various factors and the environment. The changes of the ecological environment have a significant impact on people's state of mind. As college students growing up in the new environment, their thoughts, emotions, and values are all affected by the development of the ecological environment. Therefore, changes in the ecological environment, air quality, and water environment have increasingly obvious impacts on the living environment.
MeSH term(s)	Humans ; Universities ; Ecosystem ; Educational Status ; Students ; Water
Chemical Substances	Water (059QF0KO0R)
Language	English
Publishing date	2022-10-12
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Retracted Publication
ZDB-ID	2526611-1
ISSN	1687-9813 ; 1687-9813
ISSN (online)	1687-9813
ISSN	1687-9813
DOI	10.1155/2022/9479881
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A commentary on "Global research status and frontiers on autophagy in hepatocellular carcinoma: A comprehensive bibliometric and visualized analysis".

He, Sike / Zeng, Hao

International journal of surgery (London, England)

2024

Language	English
Publishing date	2024-03-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	2212038-5
ISSN	1743-9159 ; 1743-9191
ISSN (online)	1743-9159
ISSN	1743-9191
DOI	10.1097/JS9.0000000000001343
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