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Article ; Online: New, safe and simple endoscopic cricopharyngeal myotomy with a curved rigid laryngoscope: A case report.

Maruo, Takashi / Fujimoto, Yasushi / Yokoi, Sayaka / Shigeyama, Mayu / Nishio, Naoki / Hiramatsu, Mariko / Sone, Michihiko

Molecular and clinical oncology

2023 Volume 18, Issue 2, Page(s) 10

Abstract: Endoscopic cricopharyngeal myotomy (ECPM) is a safe and minimally invasive technique that is used to treat patients whose esophageal inlet fails to open because of specific diseases, such as Wallenberg's syndrome and neuromuscular diseases. The present ... ...

Abstract	Endoscopic cricopharyngeal myotomy (ECPM) is a safe and minimally invasive technique that is used to treat patients whose esophageal inlet fails to open because of specific diseases, such as Wallenberg's syndrome and neuromuscular diseases. The present study described the performance of a new, safe and simple ECPM using a curved rigid laryngoscope, which is used for endoscopic laryngopharyngeal surgery for patients with dysphagia due to pharyngeal residue after swallowing. The patient was an 80-year-old woman with laryngeal palsy caused by lower cranial nerve palsy after cranial base schwannoma surgery. ECPM was performed with a curved rigid laryngoscope. The postoperative course was good; postoperative rehabilitation eliminated the residue after swallowing a thickened solution and mealtimes were shorter than before surgery. This procedure allows the hypopharynx to be widely expanded and it is possible to develop a wider surgical field than when using a direct laryngoscope. In addition, this procedure appears to be relatively easy to perform if the surgeon is familiar with the curved rigid laryngoscope technique.
Language	English
Publishing date	2023-01-10
Publishing country	England
Document type	Case Reports
ZDB-ID	2796865-0
ISSN	2049-9469 ; 2049-9450
ISSN (online)	2049-9469
ISSN	2049-9450
DOI	10.3892/mco.2023.2606
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Article ; Online: Development of a scoring system to quantify errors from semantic characteristics in incident reports.

Uematsu, Haruhiro / Uemura, Masakazu / Kurihara, Masaru / Yamamoto, Hiroo / Umemura, Tomomi / Kitano, Fumimasa / Hiramatsu, Mariko / Nagao, Yoshimasa

BMJ health & care informatics

2024 Volume 31, Issue 1

Abstract: Objectives: Incident reporting systems are widely used to identify risks and enable organisational learning. Free-text descriptions contain important information about factors associated with incidents. This study aimed to develop error scores by ... ...

Abstract	Objectives: Incident reporting systems are widely used to identify risks and enable organisational learning. Free-text descriptions contain important information about factors associated with incidents. This study aimed to develop error scores by extracting information about the presence of error factors in incidents using an original decision-making model that partly relies on natural language processing techniques. Methods: We retrospectively analysed free-text data from reports of incidents between January 2012 and December 2022 from Nagoya University Hospital, Japan. The sample data were randomly allocated to equal-sized training and validation datasets. We conducted morphological analysis on free text to segment terms from sentences in the training dataset. We calculated error scores for terms, individual reports and reports from staff groups according to report volume size and compared these with conventional classifications by patient safety experts. We also calculated accuracy, recall, precision and F-score values from the proposed 'report error score'. Results: Overall, 114 013 reports were included. We calculated 36 131 'term error scores' from the 57 006 reports in the training dataset. There was a significant difference in error scores between reports of incidents categorised by experts as arising from errors (p<0.001, Conclusion: Our error scoring system could provide insights to improve patient safety using aggregated incident report data.
MeSH term(s)	Humans ; Semantics ; Retrospective Studies ; Risk Management/methods ; Patient Safety ; Hospitals, University
Language	English
Publishing date	2024-04-19
Publishing country	England
Document type	Journal Article
ISSN	2632-1009
ISSN (online)	2632-1009
DOI	10.1136/bmjhci-2023-100935
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Article ; Online: Surgical reconstruction after resection of cardiac metastasis from oropharyngeal carcinoma: a case report.

Nishi, Toshihiko / Fujimoto, Kazuro L / Hiramatsu, Mariko / Okada, Tohru / Suzuki, Yuka / Shimoyama, Yoshie / Terazawa, Sachie / Tokuda, Yoshiyuki / Mutsuga, Masato / Usui, Akihiko

Nagoya journal of medical science

2023 Volume 85, Issue 4, Page(s) 875–879

MeSH term(s)	Humans ; Plastic Surgery Procedures ; Oropharyngeal Neoplasms/surgery ; Oropharyngeal Neoplasms/pathology ; Carcinoma/surgery
Language	English
Publishing date	2023-12-18
Publishing country	Japan
Document type	Case Reports
ZDB-ID	193148-9
ISSN	2186-3326 ; 0027-7622
ISSN (online)	2186-3326
ISSN	0027-7622
DOI	10.18999/nagjms.85.4.875
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Article ; Online: Development of a Novel Scoring System to Quantify the Severity of Incident Reports: An Exploratory Research Study.

Uematsu, Haruhiro / Uemura, Masakazu / Kurihara, Masaru / Umemura, Tomomi / Hiramatsu, Mariko / Kitano, Fumimasa / Fukami, Tatsuya / Nagao, Yoshimasa

Journal of medical systems

2022 Volume 46, Issue 12, Page(s) 106

Abstract: Incident reporting systems have been widely adopted to collect information about patient safety incidents. Much of the value of incident reports lies in the free-text section. Computer processing of semantic information may be helpful to analyze this. We ...

Abstract	Incident reporting systems have been widely adopted to collect information about patient safety incidents. Much of the value of incident reports lies in the free-text section. Computer processing of semantic information may be helpful to analyze this. We developed a novel scoring system for decision making to assess the severity of incidents using the semantic characteristics of the text in incident reports, and compared its results with experts' opinions. We retrospectively analyzed free-text data from incident reports from January 2012 to September 2021 at Nagoya University Hospital, Aichi, Japan. The sample was allocated to training and validation datasets using the hold-out method. Morphological analysis was used to segment terms in the training dataset. We calculated a severity term score, a severity report score and severity group score, by report volume size, and compared these with conventional severity classifications by patient safety experts and reporters. We allocated 96,082 incident reports into two groups. We calculated 1,802 severity term scores from the 48,041 reports in the training dataset. There was a significant difference in severity report score between reports categorized as severe and not severe by experts (95% confidence interval [CI] -0.83 to -0.80, p < 0.001, d = 0.81). Severity group scores were positively associated with severity ratings from experts and reporters (correlation coefficients 0.73 [95% CI 0.63-0.80, p < 0.001] and 0.79 [95% CI 0.71-0.85, p < 0.001]) for all departments. Our severity scoring system could therefore contribute to better organizational patient safety.
Language	English
Publishing date	2022-12-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	423488-1
ISSN	1573-689X ; 0148-5598
ISSN (online)	1573-689X
ISSN	0148-5598
DOI	10.1007/s10916-022-01893-1
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Article: Surgical Strategy for Squamous Cell Carcinoma of the External Auditory Canal: Management of Locally Advanced Cases with Skull Base Involvement.

Goto, Seiya / Nishio, Naoki / Iwami, Kenichiro / Yoshida, Tadao / Maruo, Takashi / Mukoyama, Nobuaki / Tsuzuki, Hidenori / Yokoi, Sayaka / Wada, Akihisa / Hiramatsu, Mariko / Hayashi, Yuichiro / Kamei, Yuzuru / Fujii, Masazumi / Sone, Michihiko / Fujimoto, Yasushi

Journal of neurological surgery. Part B, Skull base

2022 Volume 84, Issue 1, Page(s) 69–78

Abstract: ... ...

Abstract	Objective
Language	English
Publishing date	2022-02-04
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2654269-9
ISSN	2193-634X ; 2193-6331
ISSN (online)	2193-634X
ISSN	2193-6331
DOI	10.1055/a-1733-2585
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Zs.A 3425: Show issues

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Article ; Online: Comparison of chest computed tomography features between pulmonary tuberculosis patients with culture-positive and culture-negative sputum for non-mycobacteria: A retrospective observational study.

Kan, Takamasa / Komiya, Kosaku / Yamasue, Mari / Itai, Mariko / Tanaka, Ai / Takeno, Yukiko / Takikawa, Shuichi / Hiramatsu, Kazufumi / Kadota, Jun-Ichi

Medicine

2021 Volume 100, Issue 31, Page(s) e26897

Abstract: Abstract: Although complication with non-mycobacterial pneumonia among patients with pulmonary tuberculosis (TB) may lead to poor prognosis, discrimination between TB complicated with and without non-mycobacterial pneumonia using radiological imaging ... ...

Abstract	Abstract: Although complication with non-mycobacterial pneumonia among patients with pulmonary tuberculosis (TB) may lead to poor prognosis, discrimination between TB complicated with and without non-mycobacterial pneumonia using radiological imaging has not been fully elucidated. We aimed to clarify the differences in chest computed tomography (CT) features between pulmonary TB patients with culture-positive and culture-negative sputum for non-mycobacteria.We retrospectively included consecutive patients admitted to our hospital from January 2013 to December 2015 for bacteriologically-confirmed pulmonary TB, who were tested by sputum culture for non-mycobacteria, and who underwent chest CT within 2 weeks before or after admission. Chest CT features were compared between pulmonary TB patients who had positive non-mycobacterial cultures and in those who had not.Of 202 patients with pulmonary TB, 186 (92%) were tested by sputum culture for non-mycobacteria and underwent chest CT. Among these, non-mycobacteria were isolated in 118 patients (63%), while 68 patients (37%) had negative cultures. Patients with a positive culture for non-mycobacteria were significantly older and had lower levels of physical activity and albumin, higher levels of C-reactive protein, and a greater number of respiratory failures. By CT, emphysematous lesions, ground-glass opacities, airspace consolidation, air-bronchogram, interlobular septal thickening, bronchiectasis, pleural effusion, pleural thickening, and lymph node enlargement were more frequently in patients with a positive culture for non-mycobacteria. These chest CT features could be helpful for detecting complication with non-mycobacterial pneumonia in patients with pulmonary TB.
MeSH term(s)	Anti-Bacterial Agents/therapeutic use ; Community-Acquired Infections/diagnosis ; Community-Acquired Infections/epidemiology ; Diagnosis, Differential ; Diagnostic Errors/prevention & control ; Female ; Humans ; Japan/epidemiology ; Lung/diagnostic imaging ; Male ; Middle Aged ; Mycobacterium tuberculosis/isolation & purification ; Pneumonia, Bacterial/diagnosis ; Pneumonia, Bacterial/drug therapy ; Pneumonia, Bacterial/epidemiology ; Prognosis ; Retrospective Studies ; Sputum/microbiology ; Tomography, X-Ray Computed/methods ; Tuberculosis, Pulmonary/diagnosis ; Tuberculosis, Pulmonary/drug therapy ; Tuberculosis, Pulmonary/epidemiology
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2021-08-16
Publishing country	United States
Document type	Journal Article ; Observational Study
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000026897
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Article: A Novel High-Throughput Screening Method for a Human Multicentric Osteosarcoma-Specific Antibody and Biomarker Using a Phage Display-Derived Monoclonal Antibody.

Hayashi, Takuma / Yamamoto, Naoki / Kurosawa, Gene / Tajima, Kaori / Kondo, Mariko / Hiramatsu, Noriko / Kato, Yu / Tanaka, Miho / Yamaguchi, Hisateru / Kurosawa, Yoshikazu / Yamada, Harumoto / Fujita, Nobuyuki

Cancers

2022 Volume 14, Issue 23

Abstract: Osteosarcoma is a malignant tumor that produces neoplastic bone or osteoid osteoma. In human multicentric osteosarcoma (HMOS), a unique variant of human osteosarcoma (HOS), multiple bone lesions occur simultaneously or asynchronously before lung ... ...

Abstract	Osteosarcoma is a malignant tumor that produces neoplastic bone or osteoid osteoma. In human multicentric osteosarcoma (HMOS), a unique variant of human osteosarcoma (HOS), multiple bone lesions occur simultaneously or asynchronously before lung metastasis. HMOS is associated with an extremely poor prognosis, and effective treatment options are lacking. Using the proteins in our previously generated HMOS cell lines as antigens, we generated antibodies using a human antibody phage library. We obtained antibody clones recognizing 95 independent antigens and developed a fluorescence probe-based enzyme-linked immunosorbent assay (ELISA) technique capable of evaluating the reactivity of these antibodies by fluorescence intensity, allowing simple, rapid, and high-throughput selection of antibody clones. These results were highly correlated with those using flow cytometry. Subsequently, the HMOS cell lysate was incubated with the antibody, the antigen-antibody complex was recovered with magnetic beads, and the protein bands from electrophoresis were analyzed using liquid chromatography-mass spectrometry (LC/MS). CAVIN1/polymerase I transcript release factor was specifically detected in the HMOS cells. In conclusion, we found via a novel high-throughput screening method that CAVIN1/PTRF is an HMOS-specific cell membrane biomarker and an antigen capable of producing human antibodies. In the future, antibody-drug conjugate targeting of these specific proteins may be promising for clinical applications.
Language	English
Publishing date	2022-11-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527080-1
ISSN	2072-6694
ISSN	2072-6694
DOI	10.3390/cancers14235829
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Article ; Online: Safety and Clinical Benefits of Laryngeal Closure in Patients with Amyotrophic Lateral Sclerosis.

Yokoi, Sayaka / Nishio, Naoki / Maruo, Takashi / Hiramatsu, Mariko / Mukoyama, Nobuaki / Tsuzuki, Hidenori / Wada, Akihisa / Atsuta, Naoki / Ito, Daisuke / Tsuboi, Takashi / Sobue, Gen / Katsuno, Masahisa / Fujimoto, Yasushi / Sone, Michihiko

Dysphagia

2022 Volume 38, Issue 1, Page(s) 211–219

Abstract: This study evaluated the safety of laryngeal closure and post-surgical changes in swallowing function of patients with amyotrophic lateral sclerosis (ALS) and proposed an appropriate surgical strategy for patients with ALS. Clinical and surgical data of ... ...

Abstract	This study evaluated the safety of laryngeal closure and post-surgical changes in swallowing function of patients with amyotrophic lateral sclerosis (ALS) and proposed an appropriate surgical strategy for patients with ALS. Clinical and surgical data of 26 consecutive patients with ALS who underwent laryngeal closure at Nagoya University Hospital in Japan between 2003 and 2020 were retrospectively analyzed. Changes in swallowing functions were evaluated before and approximately 1 month post-surgery using Neuromuscular Disease Swallowing Status Scale (NdSSS), and Functional Oral Intake Scale (FOIS). The median operation time was 126 min (range, 51-163 min), and the median intraoperative blood loss was 20 mL (range, 0-88 mL). Among the 26 ALS patients who underwent laryngeal closure, grade 1 (mild) complications occurred in three patients (12%); however, no severe complications were observed. After surgery, 25 patients (96%) maintained the swallowing function and only one patient (4%) had deteriorating NdSSS and FOIS scores. No patients were referred to our hospital due to severe aspiration pneumonia after the surgery. Two patients did not require a feeding tube after the surgery and returned to oral intake. Laryngeal closure may be a safe surgical procedure for preventing chronic aspiration and may also maintain swallowing function of patients with ALS. Further multicenter prospective studies using the gold standard videofluoroscopic swallowing examination are required to support our findings.
MeSH term(s)	Humans ; Amyotrophic Lateral Sclerosis/complications ; Deglutition Disorders/diagnosis ; Prospective Studies ; Retrospective Studies ; Deglutition
Language	English
Publishing date	2022-05-04
Publishing country	United States
Document type	Multicenter Study ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	632764-3
ISSN	1432-0460 ; 0179-051X
ISSN (online)	1432-0460
ISSN	0179-051X
DOI	10.1007/s00455-022-10454-0
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Article ; Online: Sonographic detection of a lingual node metastasis from early squamous cell cancer of the tongue.

Nishio, Naoki / Fujimoto, Yasushi / Hiramatsu, Mariko / Yamamoto, Yoko / Sone, Michihiko

Journal of clinical ultrasound : JCU

2017 Volume 46, Issue 1, Page(s) 69–72

Abstract: Lingual node metastasis from early-stage squamous cell carcinoma of the tongue is uncommon and difficult to detect. We present a case of a lingual lymph node metastasis from an early tongue cancer. Sonography demonstrated a small nonpalpable lingual node ...

Abstract	Lingual node metastasis from early-stage squamous cell carcinoma of the tongue is uncommon and difficult to detect. We present a case of a lingual lymph node metastasis from an early tongue cancer. Sonography demonstrated a small nonpalpable lingual node on the floor of the mouth. The patient underwent complete surgical resection and had no evidence of recurrence 5 years later. © 2017 Wiley Periodicals, Inc. J Clin Ultrasound 46:69-72, 2018.
MeSH term(s)	Carcinoma, Squamous Cell/diagnostic imaging ; Carcinoma, Squamous Cell/pathology ; Female ; Head and Neck Neoplasms/diagnostic imaging ; Head and Neck Neoplasms/pathology ; Humans ; Lymph Nodes/diagnostic imaging ; Lymph Nodes/pathology ; Lymphatic Metastasis ; Middle Aged ; Squamous Cell Carcinoma of Head and Neck ; Tongue Neoplasms/diagnostic imaging ; Tongue Neoplasms/pathology ; Ultrasonography
Language	English
Publishing date	2017-04-25
Publishing country	United States
Document type	Case Reports
ZDB-ID	189393-2
ISSN	1097-0096 ; 0091-2751
ISSN (online)	1097-0096
ISSN	0091-2751
DOI	10.1002/jcu.22486
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Article: Dicationic-Type Quaternary Ammonium Salts as Candidates of Desiccants for an Air-Conditioning System

Itoh, Toshiyuki / Hiramatsu, Mariko / Kamada, Kentaro / Nokami, Toshiki / Nakayama, Hiroshi / Yagi, Kenichi / Yan, Fangyong / Kim, Hyung J.

ACS sustainable chemistry & engineering. 2021 Oct. 16, v. 9, no. 43

2021

Abstract: Liquid desiccant air conditioners contribute to sustainable living by reducing the electricity consumption. They can be driven with continuous ventilation and thus can prevent airborne transmission of infectious diseases like COVID-19. In order to ... ...

Abstract	Liquid desiccant air conditioners contribute to sustainable living by reducing the electricity consumption. They can be driven with continuous ventilation and thus can prevent airborne transmission of infectious diseases like COVID-19. In order to develop efficient desiccant materials for liquid desiccant air conditioners, we have investigated the dehumidification capability of 21 types of ammonium salts, many of them being ionic liquids. The hygroscopicity of dicationic quaternary ammonium bis(dimethyl or diethylphosphate) is found to increase with the carbon chain length of the spacer group −(CH₂)ₙ– that bridges the two terminal cationic moieties of the dication, that is, (CH₂)₂ < (CH₂)₃ < (CH₂)₆. This trend remains unchanged when methyl substituents on the cation and the phosphate anion are replaced by ethyl groups. A high dehumidification capability is obtained for N¹,N¹,N¹,N⁶,N⁶,N⁶-hexamethylhexane-1,6-diaminium bis(dimethylphosphate) ([HMC6][DMPO₄]₂) and 1,6-diethyl-1,1,6,6-tetramethylhexane-1,6-diaminium bis(diethylphosphate) ([DETMC₆][DEPO₄]₂); their capability per gram reaches almost twice that of CaCl₂, and their dehumidification rate is superior to popular solid desiccants. A favorable equilibrium water vapor pressure for the liquid desiccant air-conditioning system is attained for an 80% (w/w) aqueous solution of [HMC6][DMPO₄]₂. In addition, the 80% aqueous solution of [HMC6][DMPO₄]₂ affords no corrosive effect on steel, aluminum, and stainless steel and a very weak effect on copper. Dicationic quaternary ammonium bis(dimethyl or diethylphosphate)s are stable compounds; their aqueous solutions produce no odor after storing for over 1 year under ambient conditions. Molecular dynamics simulations are performed to gain insights into the solvation structure, energetics, and transport behavior of water in aqueous solutions of [HMC6][DMPO₄]₂ and related salts.
Keywords	COVID-19 infection ; air ; airborne transmission ; aluminum ; ammonium ; aqueous solutions ; carbon ; copper ; dehumidification ; desiccants ; electric energy consumption ; green chemistry ; hygroscopicity ; liquids ; molecular dynamics ; odors ; phosphates ; quaternary ammonium compounds ; solvation ; stainless steel ; vapor pressure ; water vapor
Language	English
Dates of publication	2021-1016
Size	p. 14502-14514.
Publishing place	American Chemical Society
Document type	Article
ISSN	2168-0485
DOI	10.1021/acssuschemeng.1c04971
Database	NAL-Catalogue (AGRICOLA)

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