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Article ; Online: Angiocentric Centrofacial Lymphoma as a Challenging Diagnosis in an Elderly Man.

Vázquez-Armenta, Gabriela / Gómez-Garnica, María Fernanda / Mondragón-Cervantes, Martha Ivón / González-Lucano, Luis Renee

The American journal of case reports

2019 Volume 20, Page(s) 412–418

Abstract: BACKGROUND Angiocentric centrofacial lymphomas, now known as nasal-type extranodal natural killer T-cell lymphomas, are neoplasms of highly destructive characteristics that mainly affect the nasal cavity and palate. The most frequent clinical ... ...

Abstract	BACKGROUND Angiocentric centrofacial lymphomas, now known as nasal-type extranodal natural killer T-cell lymphomas, are neoplasms of highly destructive characteristics that mainly affect the nasal cavity and palate. The most frequent clinical presentation includes fever, weight loss, nasal obstruction, epistaxis, nasal or facial edema, as well as necrotic ulcers in the nasal cavity, gums, and palate. It has been found to have an important association with the Epstein-Barr virus. Diagnostic pathology could be difficult due to the typical widespread tissue necrosis. CASE REPORT A 72-year-old Caucasian male sought medical attention with a chief complaint of nasal obstruction for the past 3 years, which only responded partially to unspecific treatment. He also presented with intermittent fever and nocturnal hyperhidrosis. Physical examination with rhinoscopy demonstrated a deviated septum, congestive turbines, and fragile and pale mucous membrane with yellowish, thick mucus. The pathology report described an angiocentric centrofacial lymphoma and a positive serology for Epstein-Barr virus. CONCLUSIONS The objective of this case report was to show that this illness represents a diagnostic challenge for the treating physician. It may be concluded that despite the poor prognosis of the disease, this particular case showed slower evolution and the patient remained stable despite multiple consecutive complications.
MeSH term(s)	Aged ; Epstein-Barr Virus Infections/diagnosis ; Fever/etiology ; Humans ; Hyperhidrosis/etiology ; Lymphoma, Extranodal NK-T-Cell/diagnosis ; Lymphoma, Extranodal NK-T-Cell/virology ; Male ; Nasal Obstruction/etiology ; Nose Neoplasms/diagnosis ; Nose Neoplasms/virology
Language	English
Publishing date	2019-03-30
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2517183-5
ISSN	1941-5923 ; 1941-5923
ISSN (online)	1941-5923
ISSN	1941-5923
DOI	10.12659/AJCR.913856
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Case Report: A Rare Case of a Ventricular Perivascular Epithelioid Cell Tumor With Histologic Characteristics That Resembled a Primary Cardiac Rhabdomyoma.

Cossío-Aranda, Jorge / Aranda-Frausto, Alberto / Berarducci, Joaquin / Espinola-Zavaleta, Nilda / González-Melchor, Laila / Vázquez-Antona, Clara / Meléndez-Ramirez, Gabriela / Armenta-Moreno, Javier Ivan / Keirns, Candace

Frontiers in cardiovascular medicine

2021 Volume 8, Page(s) 709328

Abstract: We present the case of a young male patient with an initial diagnosis of a rhabdomyoma that was surgically treated at a different hospital when he was 17. After a 2-year disease-free period, the patient presented another intra-cardiac mass. He refused ... ...

Abstract	We present the case of a young male patient with an initial diagnosis of a rhabdomyoma that was surgically treated at a different hospital when he was 17. After a 2-year disease-free period, the patient presented another intra-cardiac mass. He refused surgical treatment and died 5 years later. Post-mortem immunochemistry studies of both tumors led to the diagnosis of a primary malignant cardiac PEComa with histopathologic characteristics that resembled a rhabdomyoma with abundant "spider cells."
Language	English
Publishing date	2021-10-25
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2781496-8
ISSN	2297-055X
ISSN	2297-055X
DOI	10.3389/fcvm.2021.709328
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Article ; Online: Modulation of antioxidant defense system after long term arsenic exposure in Zantedeschia aethiopica and Anemopsis californica.

Del-Toro-Sánchez, Carmen Lizette / Zurita, Florentina / Gutiérrez-Lomelí, Melesio / Solis-Sánchez, Brenda / Wence-Chávez, Laura / Rodríguez-Sahagún, Araceli / Castellanos-Hernández, Osvaldo A / Vázquez-Armenta, Gabriela / Siller-López, Fernando

Ecotoxicology and environmental safety

2013 Volume 94, Page(s) 67–72

Abstract: Zantedeschia aethiopica (calla lily) and Anemopsis californica (yerba mansa) are plant species capable of accumulating arsenic (As) and therefore proposed as phytoremediation for removal of As from drinking water. The effects of a continuous 6 month As ... ...

Abstract	Zantedeschia aethiopica (calla lily) and Anemopsis californica (yerba mansa) are plant species capable of accumulating arsenic (As) and therefore proposed as phytoremediation for removal of As from drinking water. The effects of a continuous 6 month As exposure (34±11 μg/L) from local contaminated groundwater on the antioxidant response of Z. aethiopica and A. californica were evaluated in leaves and stems of the plants bimonthly in a subsurface flow constructed wetland. As increased the activities of the antioxidant enzymes ascorbate peroxidase, glutathione reductase and catalase where higher levels were observed in Z. aethiopica than A. californica. No significant differences were detected on lipid peroxidation levels or antioxidant capacity evaluated by ORAC and DPPH assays or total phenol contents in any part of the plant, although in general the leaves of both plants showed the best antioxidant defense against the metal. In conclusion, Z. aethiopica and A. californica were able to cope to As through induction of a more sensitive enzymatic antioxidant response mechanism.
MeSH term(s)	Arsenic/toxicity ; Ascorbate Peroxidases/metabolism ; Biodegradation, Environmental ; Catalase/metabolism ; Dose-Response Relationship, Drug ; Glutathione Reductase/metabolism ; Lipid Peroxidation/drug effects ; Phenols/metabolism ; Plant Leaves/metabolism ; Saururaceae/drug effects ; Saururaceae/metabolism ; Soil Pollutants/toxicity ; Zantedeschia/drug effects ; Zantedeschia/metabolism
Chemical Substances	Phenols ; Soil Pollutants ; Ascorbate Peroxidases (EC 1.11.1.11) ; Catalase (EC 1.11.1.6) ; Glutathione Reductase (EC 1.8.1.7) ; Arsenic (N712M78A8G)
Language	English
Publishing date	2013-05-17
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	436536-7
ISSN	1090-2414 ; 0147-6513
ISSN (online)	1090-2414
ISSN	0147-6513
DOI	10.1016/j.ecoenv.2013.04.024
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Article ; Online: Short (GT)n microsatellite repeats in the heme oxygenase-1 gene promoter are associated with antioxidant and anti-inflammatory status in Mexican pediatric patients with sepsis.

Vázquez-Armenta, Gabriela / González-Leal, Natalia / J Vázquez-de la Torre, Mayra / Muñoz-Valle, José Francisco / Ramos-Márquez, Martha E / Hernández-Cañaveral, Iván / Plascencia-Hernández, Arturo / Siller-López, Fernando

The Tohoku journal of experimental medicine

2012 Volume 231, Issue 3, Page(s) 201–209

Abstract: An adequate immune and antioxidant response is a key to the resolution of sepsis. Heme oxygenase-1 (HMOX1) is a stress protein with a polymorphic (GT)n repeat in its gene promoter that regulates its expression in response to oxidative injury, such as ... ...

Abstract	An adequate immune and antioxidant response is a key to the resolution of sepsis. Heme oxygenase-1 (HMOX1) is a stress protein with a polymorphic (GT)n repeat in its gene promoter that regulates its expression in response to oxidative injury, such as that present in sepsis. HMOX1 is the rate-limiting enzyme of heme degradation, and the heme breakdown products, CO, Fe, and bilirubin, are considered to be biologically active metabolites with direct or indirect antioxidant and anti-inflammatory properties. In this study, we investigated the inflammatory and antioxidant response and the relationship with the HMOX1 levels and HMOX1 polymorphism in Mexican septic pediatric patients. In a case-control pilot study, we enrolled 64 septic patients and 72 hospitalized control patients without a diagnosis of sepsis. DNA extracted from buffy coat was genotyped for HMOX1 (GT)n polymorphism by PCR and markers of antioxidant and inflammatory status were quantified in plasma by analysis of the oxygen radical absorbance capacity (ORAC), protein carbonyl (PC), interleukin (IL) 6, IL10, and HMOX1 levels. In septic children, oxidative and inflammatory markers were elevated, and HMOX1 levels were positively correlated with IL10 levels. Genotypic and allelic distribution of HMOX1 polymorphism showed no difference between groups. HMOX1 short-allele septic carriers (< 25 GT repeats) presented favorable ORAC, PC and IL10 levels. This study confirms that an active response against pediatric sepsis involves the expression of HMOX1 and IL10, suggesting that the high antioxidant status associated with HMOX1 short-allele septic carriers might provide a beneficial environment for sepsis resolution.
MeSH term(s)	Adolescent ; Anti-Inflammatory Agents/metabolism ; Antioxidants/metabolism ; Biomarkers/blood ; Case-Control Studies ; Child ; Child, Preschool ; Cytokines/blood ; Demography ; Female ; Gene Frequency/genetics ; Genetic Predisposition to Disease ; Heme Oxygenase-1/genetics ; Humans ; Infant ; Male ; Mexico ; Microsatellite Repeats/genetics ; Oxidation-Reduction ; Promoter Regions, Genetic ; Sepsis/blood ; Sepsis/enzymology ; Sepsis/genetics ; Sepsis/microbiology ; Statistics, Nonparametric
Chemical Substances	Anti-Inflammatory Agents ; Antioxidants ; Biomarkers ; Cytokines ; HMOX1 protein, human (EC 1.14.14.18) ; Heme Oxygenase-1 (EC 1.14.14.18)
Language	English
Publishing date	2012-10-08
Publishing country	Japan
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	123477-8
ISSN	1349-3329 ; 0040-8727
ISSN (online)	1349-3329
ISSN	0040-8727
DOI	10.1620/tjem.231.201
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Article ; Online: The fatal contribution of serine protease-related genetic variants to COVID-19 outcomes.

Martínez-Gómez, Laura Edith / Martinez-Armenta, Carlos / Tusie-Luna, Teresa / Vázquez-Cárdenas, Paola / Vidal-Vázquez, Rosa P / Ramírez-Hinojosa, Juan P / Gómez-Martín, Diana / Vargas-Alarcón, Gilberto / Posadas-Sánchez, Rosalinda / Fragoso, José Manuel / de la Peña, Aurora / Rodríguez-Pérez, José Manuel / Mata-Miranda, Mónica M / Vázquez-Zapién, Gustavo J / Martínez-Cuazitl, Adriana / Martínez-Ruiz, Felipe de J / Zayago-Angeles, Dulce M / Ramos-Tavera, Luis / Méndez-Aguilera, Alberto /

Camacho-Rea, María Del C / Ordoñez-Sánchez, María L / Segura-Kato, Yayoi / Suarez-Ahedo, Carlos / Olea-Torres, Jessel / Herrera-López, Brígida / Pineda, Carlos / Martínez-Nava, Gabriela A / López-Reyes, Alberto

Frontiers in immunology

2024 Volume 15, Page(s) 1335963

Abstract: Introduction: Serine proteases play a critical role during SARS-CoV-2 infection. Therefore, polymorphisms of transmembrane protease serine 2 (: Methods: To evaluate the genetic variants of the genes previously associated with COVID-19 outcomes, we ... ...

Abstract	Introduction: Serine proteases play a critical role during SARS-CoV-2 infection. Therefore, polymorphisms of transmembrane protease serine 2 ( Methods: To evaluate the genetic variants of the genes previously associated with COVID-19 outcomes, we performed a cross-sectional study in which 1536 SARS-CoV-2-positive participants were enrolled. Results: According to our codominant model, the GA genotype of rs2227667 (OR=0.55; 95% CI = 0.36-0.84; Discussion: Our data suggest that the rs75603675
MeSH term(s)	Humans ; COVID-19/genetics ; Serine Proteases ; SARS-CoV-2 ; Diabetes Mellitus, Type 2 ; Cross-Sectional Studies
Chemical Substances	Serine Proteases (EC 3.4.-)
Language	English
Publishing date	2024-03-27
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2024.1335963
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Article ; Online: NLRP3 Inflammasome: The Stormy Link Between Obesity and COVID-19.

López-Reyes, Alberto / Martinez-Armenta, Carlos / Espinosa-Velázquez, Rocio / Vázquez-Cárdenas, Paola / Cruz-Ramos, Marlid / Palacios-Gonzalez, Berenice / Gomez-Quiroz, Luis Enrique / Martínez-Nava, Gabriela Angélica

Frontiers in immunology

2020 Volume 11, Page(s) 570251

Abstract: Several countries around the world have faced an important obesity challenge for the past four decades as the result of an obesogenic environment. This disease has a multifactorial origin and it is associated with multiple comorbidities including type 2 ... ...

Abstract	Several countries around the world have faced an important obesity challenge for the past four decades as the result of an obesogenic environment. This disease has a multifactorial origin and it is associated with multiple comorbidities including type 2 diabetes, hypertension, osteoarthritis, metabolic syndrome, cancer, and dyslipidemia. With regard to dyslipidemia, hypertriglyceridemia is a well-known activator of the NLRP3 inflammasome, triggering adipokines and cytokines secretion which in addition induce a systemic inflammatory state that provides an adequate scenario for infections, particularly those mediated by viruses such as HIV, H1N1 influenza, and SARS-CoV-2. The SARS-CoV-2 infection causes the coronavirus disease 2019 (COVID-19) and it is responsible for the pandemic that we are currently living. COVID-19 causes an aggressive immune response known as cytokine release syndrome or cytokine storm that causes multiorgan failure and in most cases leads to death. In the present work, we aimed to review the molecular mechanisms by which obesity-associated systemic inflammation could cause a more severe clinical presentation of COVID-19. The SARS-CoV-2 infection could potentiate or accelerate the pre-existing systemic inflammatory state of individuals with obesity,
MeSH term(s)	Animals ; COVID-19/genetics ; COVID-19/immunology ; COVID-19/virology ; Cytokine Release Syndrome/genetics ; Cytokine Release Syndrome/immunology ; Cytokine Release Syndrome/virology ; Cytokines/genetics ; Cytokines/immunology ; Diabetes Mellitus, Type 2/genetics ; Diabetes Mellitus, Type 2/immunology ; Diabetes Mellitus, Type 2/virology ; Humans ; Inflammasomes/genetics ; Inflammasomes/immunology ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; NLR Family, Pyrin Domain-Containing 3 Protein/immunology ; SARS-CoV-2/genetics ; SARS-CoV-2/physiology
Chemical Substances	Cytokines ; Inflammasomes ; NLR Family, Pyrin Domain-Containing 3 Protein
Keywords	covid19
Language	English
Publishing date	2020-10-30
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2020.570251
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Article: Removal of Cadmium from Aqueous Solutions by

Moreno Rivas, Silvia Carolina / Armenta Corral, Rosa Idalia / Frasquillo Félix, María Del Carmen / Islas Rubio, Alma Rosa / Vázquez Moreno, Luz / Ramos-Clamont Montfort, Gabriela

Materials (Basel, Switzerland)

2019 Volume 12, Issue 24

Abstract: The aim of this study was to determine the ... ...

Abstract	The aim of this study was to determine the Cd
Language	English
Publishing date	2019-12-10
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2487261-1
ISSN	1996-1944
ISSN	1996-1944
DOI	10.3390/ma12244128
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Article: Modulation of antioxidant defense system after long term arsenic exposure in Zantedeschia aethiopica and Anemopsis californica

Del-Toro-Sánchez, Carmen Lizette / Zurita, Florentina / Gutiérrez-Lomelí, Melesio / Solis-Sánchez, Brenda / Wence-Chávez, Laura / Rodríguez-Sahagún, Araceli / Castellanos-Hernández, Osvaldo A. / Vázquez-Armenta, Gabriela / Siller-López, Fernando

Ecotoxicology and environmental safety

2013 Volume 94, Issue 1, Page(s) 67

Language	English
Document type	Article
ZDB-ID	436536-7
ISSN	0147-6513
Database	Current Contents Nutrition, Environment, Agriculture

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Article ; Online: Implication of myddosome complex genetic variants in outcome severity of COVID-19 patients.

Martínez-Gómez, Laura E / Martinez-Armenta, Carlos / Medina-Luna, Daniel / Ordoñez-Sánchez, María Luisa / Tusie-Luna, Tere / Ortega-Peña, Silvestre / Herrera-López, Brígida / Suarez-Ahedo, Carlos / Jimenez-Gutierrez, Guadalupe Elizabeth / Hidalgo-Bravo, Alberto / Vázquez-Cárdenas, Paola / Vidal-Vázquez, Rosa P / Ramírez-Hinojosa, Juan P / Martinez Matsumoto, Pilar Miyoko / Vargas-Alarcón, Gilberto / Posadas-Sánchez, Rosalinda / Fragoso, José-Manuel / Martínez-Ruiz, Felipe de J / Zayago-Angeles, Dulce M /

Mata-Miranda, Mónica Maribel / Vázquez-Zapién, Gustavo Jesús / Martínez-Cuazitl, Adriana / Andrade-Alvarado, Javier / Granados, Julio / Ramos-Tavera, Luis / Camacho-Rea, María Del Carmen / Segura-Kato, Yayoi / Rodríguez-Pérez, José Manuel / Coronado-Zarco, Roberto / Franco-Cendejas, Rafael / López-Jácome, Luis Esau / Magaña, Jonathan J / Vela-Amieva, Marcela / Pineda, Carlos / Martínez-Nava, Gabriela Angélica / López-Reyes, Alberto

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi

2023 Volume 56, Issue 5, Page(s) 939–950

Abstract: Background/purpose(s): During a viral infection, the immune response is mediated by the toll-like receptors and myeloid differentiation Factor 88 (MyD88) that play an important role sensing infections such as SARS-CoV-2 which has claimed the lives of ... ...

Abstract	Background/purpose(s): During a viral infection, the immune response is mediated by the toll-like receptors and myeloid differentiation Factor 88 (MyD88) that play an important role sensing infections such as SARS-CoV-2 which has claimed the lives of more than 6.8 million people around the world. Methods: We carried out a cross-sectional with a population of 618 SARS-CoV-2-positive unvaccinated subjects and further classified based on severity: 22% were mild, 34% were severe, 26% were critical, and 18% were deceased. Toll Like Receptor 7 (TLR7) single-nucleotide polymorphisms (rs3853839, rs179008, rs179009, and rs2302267) and MyD88 (rs7744) were genotyped using TaqMan OpenArray. The association of polymorphisms with disease outcomes was performed by logistic regression analysis adjusted by covariates. Results: A significant association of rs3853839 and rs7744 of the TLR7 and MyD88 genes, respectively, was found with COVID-19 severity. The G/G genotype of the rs3853839 TLR7 was associated with the critical outcome showing an Odd Ratio = 1.98 (95% IC = 1.04-3.77). The results highlighted an association of the G allele of MyD88 gene with severe, critical and deceased outcomes. Furthermore, in the dominant model (AG + GG vs. AA), we observed an Odd Ratio = 1.70 (95% CI = 1.02-2.86) with severe, Odd Ratio = 1.82 (95% CI = 1.04-3.21) with critical, and Odd Ratio = 2.44 (95% CI = 1.21-4.9) with deceased outcomes. Conclusion: To our knowledge this work represents an innovative report that highlights the significant association of TLR7 and MyD88 gene polymorphisms with COVID-19 outcomes and the possible implication of the MyD88 variant with D-dimer and IFN-α concentrations.
MeSH term(s)	Humans ; Toll-Like Receptor 7/genetics ; Toll-Like Receptor 7/metabolism ; Genetic Predisposition to Disease ; Myeloid Differentiation Factor 88/genetics ; Cross-Sectional Studies ; COVID-19/genetics ; SARS-CoV-2 ; Genotype ; Polymorphism, Single Nucleotide/genetics
Chemical Substances	Toll-Like Receptor 7 ; Myeloid Differentiation Factor 88
Language	English
Publishing date	2023-06-16
Publishing country	England
Document type	Journal Article
ZDB-ID	1497590-7
ISSN	1995-9133 ; 1684-1182 ; 0253-2662
ISSN (online)	1995-9133
ISSN	1684-1182 ; 0253-2662
DOI	10.1016/j.jmii.2023.06.002
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Article ; Online: Family functionality in pediatric asthma patients in a public hospital in Sonora, Mexico.

Gabriela Vázquez Armenta / Francisca Cecilia Ramírez Enríquez / Diana Gabriela Trejo Ramos / Jaime Guadalupe Valle Leal / Cruz Mónica López-Morales

Revista Facultad de Ciencias de la Salud UDES, Vol 3, Iss 1, Pp 46-

2016 Volume 50

Abstract: Introduction: The family and psychological approaches in asthma patients are essential because a dysfunctional family can increase asthma symptoms of the sick child. Aim: To determine family functioning and classification of asthma in pediatric patients, ...

Abstract	Introduction: The family and psychological approaches in asthma patients are essential because a dysfunctional family can increase asthma symptoms of the sick child. Aim: To determine family functioning and classification of asthma in pediatric patients, and the condition in the areas that comprises it. Method: A cross-sectional study in asthmatic patients treated in pediatrics Regional General Hospital No. 1 between April and July 2015 was done. Asthma severity was classified in response to the GINA 2010 guide. The Dr. Emma Espejel Scale of Family Functioning was applied to the patient's family. Results: The male presented more severe asthma by 70%, especially in school age. The dysfunction of the control area of family dynamics in the Mexican family impact on the severity of asthma. Discussion and Conclusion: 50% of families with a carrier member of asthma reflect dysfunction; control area was the most affected. Family and psychological approaches in patients with asthma are basic to prevent changes in family function.
Keywords	Asma ; familia ; niños ; Medicine ; R ; Medicine (General) ; R5-920
Subject code	616
Language	Spanish
Publishing date	2016-06-01T00:00:00Z
Publisher	Universidad de Santander
Document type	Article ; Online
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