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  1. Article ; Online: Reproducibility and Repeatability Tests on (SnTiNb)O

    Astolfi, Michele / Rispoli, Giorgio / Gherardi, Sandro / Zonta, Giulia / Malagù, Cesare

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 4

    Abstract: Nowadays, most medical-diagnostic, environmental monitoring, etc. devices employ sensors whose fabrication reproducibility and response repeatability assessment are crucial. The former consists of large-scale sensor manufacture through a standardized ... ...

    Abstract Nowadays, most medical-diagnostic, environmental monitoring, etc. devices employ sensors whose fabrication reproducibility and response repeatability assessment are crucial. The former consists of large-scale sensor manufacture through a standardized process with almost identical morphology and behavior, while the latter consists of giving the same response upon repeating the same stimulus. The thermo-activated chemoresistive sensors, which change their conductance by interacting with the molecules composing the surrounding gas, are currently employed in many devices: in particular, thick-film (SnTiNb)O
    Language English
    Publishing date 2023-02-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23041983
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A Portable Device for I-V and Arrhenius Plots to Characterize Chemoresistive Gas Sensors: Test on SnO

    Astolfi, Michele / Zonta, Giulia / Gherardi, Sandro / Malagù, Cesare / Vincenzi, Donato / Rispoli, Giorgio

    Nanomaterials (Basel, Switzerland)

    2023  Volume 13, Issue 18

    Abstract: Chemoresistive nanostructured gas sensors are employed in many diverse applications in the medical, industrial, environmental, etc. fields; therefore, it is crucial to have a device that is able to quickly calibrate and characterize them. To this aim, a ... ...

    Abstract Chemoresistive nanostructured gas sensors are employed in many diverse applications in the medical, industrial, environmental, etc. fields; therefore, it is crucial to have a device that is able to quickly calibrate and characterize them. To this aim, a portable, user-friendly device designed to easily calibrate a sensor in laboratory and/or on field is introduced here. The device comprises a small hermetically sealed chamber (containing the sensor socket and a temperature/humidity sensor), a pneumatic system, and a custom electronics controlled by a Raspberry Pi 4 developing board, running a custom software (Version 1.0) whose user interface is accessed via a multitouch-screen. This device automatically characterizes the sensor heater in order to precisely set the desired working temperature, it acquires and plots the sensor current-to-voltage and Arrhenius relationships on the touch screen, and it can record the sensor responses to different gases and environments. These tests were performed in dry air on two representative sensors based on widely used SnO
    Language English
    Publishing date 2023-09-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano13182549
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  3. Article ; Online: Endoscopic full-thickness resection of a submucosal right colon lesion.

    Salerno, Raffaele / Gherardi, Giorgio / Paternò, Emanuela / Ardizzone, Sandro

    Endoscopy

    2016  Volume 48, Issue S 01, Page(s) E376–E377

    MeSH term(s) Colonic Neoplasms/surgery ; Endoscopy, Gastrointestinal/methods ; Female ; Humans ; Lymphoma, Large B-Cell, Diffuse/pathology ; Lymphoma, Large B-Cell, Diffuse/surgery ; Middle Aged
    Language English
    Publishing date 2016
    Publishing country Germany
    Document type Case Reports ; Journal Article ; Video-Audio Media
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-0042-120338
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 669: Show issues Location:
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  4. Article ; Online: A new strategy to prevent biofilm and clot formation in medical devices: The use of atmospheric non-thermal plasma assisted deposition of silver-based nanostructured coatings.

    Gallingani, Tommaso / Resca, Elisa / Dominici, Massimo / Gavioli, Giuliana / Laurita, Romolo / Liguori, Anna / Mari, Giorgio / Ortolani, Luca / Pericolini, Eva / Sala, Arianna / Laghi, Giulia / Petrachi, Tiziana / Arnauld, Gaëlle Francoise / Accorsi, Luca / Rizzoli, Rita / Colombo, Vittorio / Gherardi, Matteo / Veronesi, Elena

    PloS one

    2023  Volume 18, Issue 2, Page(s) e0282059

    Abstract: In industrialized countries, health care associated infections, the fourth leading cause of disease, are a major health issue. At least half of all cases of nosocomial infections are associated with medical devices. Antibacterial coatings arise as an ... ...

    Abstract In industrialized countries, health care associated infections, the fourth leading cause of disease, are a major health issue. At least half of all cases of nosocomial infections are associated with medical devices. Antibacterial coatings arise as an important approach to restrict the nosocomial infection rate without side effects and the development of antibiotic resistance. Beside nosocomial infections, clot formation affects cardiovascular medical devices and central venous catheters implants. In order to reduce and prevent such infection, we develop a plasma-assisted process for the deposition of nanostructured functional coatings on flat substrates and mini catheters. Silver nanoparticles (Ag NPs) are synthesized exploiting in-flight plasma-droplet reactions and are embedded in an organic coating deposited through hexamethyldisiloxane (HMDSO) plasma assisted polymerization. Coating stability upon liquid immersion and ethylene oxide (EtO) sterilization is assessed through chemical and morphological analysis carried out by means of Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). In the perspective of future clinical application, an in vitro analysis of anti-biofilm effect has been done. Moreover, we employed a murine model of catheter-associated infection which further highlighted the performance of Ag nanostructured films in counteract biofilm formation. The anti-clot performances coupled by haemo- and cytocompatibility assays have also been performed.
    MeSH term(s) Mice ; Animals ; Silver/chemistry ; Coated Materials, Biocompatible/chemistry ; Metal Nanoparticles ; Anti-Bacterial Agents/pharmacology ; Biofilms
    Chemical Substances Silver (3M4G523W1G) ; Coated Materials, Biocompatible ; Anti-Bacterial Agents
    Language English
    Publishing date 2023-02-22
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0282059
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A new strategy to prevent biofilm and clot formation in medical devices

    Tommaso Gallingani / Elisa Resca / Massimo Dominici / Giuliana Gavioli / Romolo Laurita / Anna Liguori / Giorgio Mari / Luca Ortolani / Eva Pericolini / Arianna Sala / Giulia Laghi / Tiziana Petrachi / Gaëlle Francoise Arnauld / Luca Accorsi / Rita Rizzoli / Vittorio Colombo / Matteo Gherardi / Elena Veronesi

    PLoS ONE, Vol 18, Iss 2, p e

    The use of atmospheric non-thermal plasma assisted deposition of silver-based nanostructured coatings.

    2023  Volume 0282059

    Abstract: In industrialized countries, health care associated infections, the fourth leading cause of disease, are a major health issue. At least half of all cases of nosocomial infections are associated with medical devices. Antibacterial coatings arise as an ... ...

    Abstract In industrialized countries, health care associated infections, the fourth leading cause of disease, are a major health issue. At least half of all cases of nosocomial infections are associated with medical devices. Antibacterial coatings arise as an important approach to restrict the nosocomial infection rate without side effects and the development of antibiotic resistance. Beside nosocomial infections, clot formation affects cardiovascular medical devices and central venous catheters implants. In order to reduce and prevent such infection, we develop a plasma-assisted process for the deposition of nanostructured functional coatings on flat substrates and mini catheters. Silver nanoparticles (Ag NPs) are synthesized exploiting in-flight plasma-droplet reactions and are embedded in an organic coating deposited through hexamethyldisiloxane (HMDSO) plasma assisted polymerization. Coating stability upon liquid immersion and ethylene oxide (EtO) sterilization is assessed through chemical and morphological analysis carried out by means of Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). In the perspective of future clinical application, an in vitro analysis of anti-biofilm effect has been done. Moreover, we employed a murine model of catheter-associated infection which further highlighted the performance of Ag nanostructured films in counteract biofilm formation. The anti-clot performances coupled by haemo- and cytocompatibility assays have also been performed.
    Keywords Medicine ; R ; Science ; Q
    Subject code 620
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Endoscopic full-thickness resection of a submucosal right colon lesion

    Salerno, Raffaele / Gherardi, Giorgio / Paternò, Emanuela / Ardizzone, Sandro

    Endoscopy

    2016  Volume 48, Issue S 01, Page(s) E376–E377

    Language English
    Publishing date 2016-01-01
    Publisher © Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-0042-120338
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 669: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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    Zs.MO 162: Show issues

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  7. Article ; Online: Organochlorines and Polycyclic Aromatic Hydrocarbons as fingerprint of exposure pathways from marine sediments to biota.

    Traina, Anna / Ausili, Antonella / Bonsignore, Maria / Fattorini, Daniele / Gherardi, Serena / Gorbi, Stefania / Quinci, Enza / Romano, Elena / Salvagio Manta, Daniela / Tranchida, Giorgio / Regoli, Francesco / Sprovieri, Mario

    Marine pollution bulletin

    2021  Volume 170, Page(s) 112676

    Abstract: To elucidate the dynamics of a suite of organochlorine contaminants (PCBs, HCB), PAHs and Hg and verify the potential of these pollutants as reliable fingerprints of sources, an ensemble of marine sediments and organisms (finfish, shellfish species and ... ...

    Abstract To elucidate the dynamics of a suite of organochlorine contaminants (PCBs, HCB), PAHs and Hg and verify the potential of these pollutants as reliable fingerprints of sources, an ensemble of marine sediments and organisms (finfish, shellfish species and Mytilus galloprovincialis) were analysed from the contaminated Augusta Bay (Southern Italy). The Hg and HCB concentration in the sediments exceeded the EQS of the Directive 2000/60/EU. Similarly, ∑PCB and selected PAHs were above the threshold limit set by regulation. The marine organisms showed Hg concentrations above CE 1881/2006. Contaminants in transplanted mussel evidenced an increased accumulation overtime and different distribution patterns between sampling sites. Analysis of the homolog composition of PCB congeners revealed comparable patterns between sediments and marine organisms and offered the opportunity to define a robust fingerprint for tracing contaminants transfer from the abiotic to the biotic compartments. These results were confirmed by the Fluoranthene/Pyrene, Hg and HCB distribution modes.
    MeSH term(s) Animals ; Biota ; Environmental Monitoring ; Geologic Sediments ; Mytilus ; Polycyclic Aromatic Hydrocarbons/analysis ; Water Pollutants, Chemical/analysis
    Chemical Substances Polycyclic Aromatic Hydrocarbons ; Water Pollutants, Chemical
    Language English
    Publishing date 2021-07-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2001296-2
    ISSN 1879-3363 ; 0025-326X
    ISSN (online) 1879-3363
    ISSN 0025-326X
    DOI 10.1016/j.marpolbul.2021.112676
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  8. Article: Organochlorines and Polycyclic Aromatic Hydrocarbons as fingerprint of exposure pathways from marine sediments to biota

    Traina, Anna / Ausili, Antonella / Bonsignore, Maria / Fattorini, Daniele / Gherardi, Serena / Gorbi, Stefania / Quinci, Enza / Romano, Elena / Salvagio Manta, Daniela / Tranchida, Giorgio / Regoli, Francesco / Sprovieri, Mario

    Marine pollution bulletin. 2021 Sept., v. 170

    2021  

    Abstract: To elucidate the dynamics of a suite of organochlorine contaminants (PCBs, HCB), PAHs and Hg and verify the potential of these pollutants as reliable fingerprints of sources, an ensemble of marine sediments and organisms (finfish, shellfish species and ... ...

    Abstract To elucidate the dynamics of a suite of organochlorine contaminants (PCBs, HCB), PAHs and Hg and verify the potential of these pollutants as reliable fingerprints of sources, an ensemble of marine sediments and organisms (finfish, shellfish species and Mytilus galloprovincialis) were analysed from the contaminated Augusta Bay (Southern Italy). The Hg and HCB concentration in the sediments exceeded the EQS of the Directive 2000/60/EU. Similarly, ∑PCB and selected PAHs were above the threshold limit set by regulation. The marine organisms showed Hg concentrations above CE 1881/2006. Contaminants in transplanted mussel evidenced an increased accumulation overtime and different distribution patterns between sampling sites. Analysis of the homolog composition of PCB congeners revealed comparable patterns between sediments and marine organisms and offered the opportunity to define a robust fingerprint for tracing contaminants transfer from the abiotic to the biotic compartments. These results were confirmed by the Fluoranthene/Pyrene, Hg and HCB distribution modes.
    Keywords Mytilus galloprovincialis ; fish ; marine pollution ; mussels ; shellfish ; Italy
    Language English
    Dates of publication 2021-09
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 2001296-2
    ISSN 1879-3363 ; 0025-326X
    ISSN (online) 1879-3363
    ISSN 0025-326X
    DOI 10.1016/j.marpolbul.2021.112676
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Genetic variants of PARP4 gene and PARP4P2 pseudogene in patients with multiple primary tumors including thyroid cancer.

    Cirello, Valentina / Colombo, Carla / Pogliaghi, Gabriele / Proverbio, Maria Carla / Rossi, Stefania / Mussani, Elena / Tosi, Delfina / Bulfamante, Gaetano / Bonoldi, Emanuela / Gherardi, Giorgio / Persani, Luca / Fugazzola, Laura

    Mutation research

    2019  Volume 816-818, Page(s) 111672

    Abstract: Recently, the PARP4 gene has been identified as a possible susceptibility gene of primary thyroid and breast cancers. We analyzed PARP4 in 53 patients with multiple primary cancers including a thyroid cancer (TC), in 74 patients with TC alone, and in 88 ... ...

    Abstract Recently, the PARP4 gene has been identified as a possible susceptibility gene of primary thyroid and breast cancers. We analyzed PARP4 in 53 patients with multiple primary cancers including a thyroid cancer (TC), in 74 patients with TC alone, and in 88 healthy donors. Two PARP4 intronic variants within the IVS29 (c.3543 + 44T > C) and the IVS22 (c.2758 + 9G > A) were found only in the two patient groups. Moreover, we found a rare variant (r.522C > A) within a PARP4 pseudogene (PARP4P2) in one patient with four primary tumors, and with a familial cancer history. PARP4 mRNA was absent in all primary tumors and matched normal tissues, whereas the pseudogene variant transcript was always expressed. Consistently, immunostaining for PARP4 protein was negative at nuclear level in all tissues, thus suggesting that PARP4P2 pseudogene variant could alter its regulatory role on PARP4, inducing the down-regulation of PARP4 expression at both tumor and normal tissues level. In conclusion, germline intronic PARP4 variants could be a risk factor for the development of TC, and PARP4P2 pseudogene variations associated with PARP4 down-regulation may confer susceptibility to develop multiple metachronous cancers.
    MeSH term(s) Adolescent ; Adult ; Aged ; Down-Regulation/genetics ; Female ; Genetic Predisposition to Disease/genetics ; Germ-Line Mutation/genetics ; Humans ; Male ; Middle Aged ; Neoplasms, Multiple Primary/genetics ; Nuclear Proteins/genetics ; Pseudogenes/genetics ; Thyroid Neoplasms/genetics ; Young Adult
    Chemical Substances Nuclear Proteins ; PARP4 protein, human
    Language English
    Publishing date 2019-06-01
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 206607-5
    ISSN 1873-135X ; 1383-5718 ; 0027-5107 ; 0165-1110 ; 0165-1161 ; 0165-7992 ; 0921-8777 ; 0165-1218 ; 1383-5726 ; 0167-8817 ; 0921-8734 ; 1383-5742
    ISSN (online) 1873-135X
    ISSN 1383-5718 ; 0027-5107 ; 0165-1110 ; 0165-1161 ; 0165-7992 ; 0921-8777 ; 0165-1218 ; 1383-5726 ; 0167-8817 ; 0921-8734 ; 1383-5742
    DOI 10.1016/j.mrfmmm.2019.111672
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1316: Show issues Location:
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  10. Article ; Online: Cold atmospheric plasma inactivation of aerosolized microdroplets containing bacteria and purified SARS‐CoV‐2 RNA to contrast airborne indoor transmission

    Bisag, Alina / Isabelli, Pasquale / Laurita, Romolo / Bucci, Cristiana / Capelli, Filippo / Dirani, Giorgio / Gherardi, Matteo / Laghi, Giulia / Paglianti, Alessandro / Sambri, Vittorio / Colombo, Vittorio

    Plasma Processes and Polymers

    2020  Volume 17, Issue 10, Page(s) 2000154

    Keywords Polymers and Plastics ; Condensed Matter Physics ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ISSN 1612-8850
    DOI 10.1002/ppap.202000154
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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