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Article ; Online: Spring Design of Triboelectric Nanogenerator with MXene-Modified Interface for Fluid Energy Harvesting and Water Level Monitoring.

Tao, Yang / Xiang, Huijing / Cao, Xia / Wang, Ning

ACS applied materials & interfaces

2024 Volume 16, Issue 3, Page(s) 3406–3415

Abstract: The introduction of two-dimensional materials with high capacitance that are dielectric into the triboelectric interface is critical for the development of a highly efficient triboelectric nanogenerator (TENG) due to its excellent electrical conductivity ...

Abstract	The introduction of two-dimensional materials with high capacitance that are dielectric into the triboelectric interface is critical for the development of a highly efficient triboelectric nanogenerator (TENG) due to its excellent electrical conductivity and versatile surface chemistry. This paper reports a spring-structured multilayer TENG (S-TENG), where a Nb
Language	English
Publishing date	2024-01-12
Publishing country	United States
Document type	Journal Article
ISSN	1944-8252
ISSN (online)	1944-8252
DOI	10.1021/acsami.3c15558
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Article ; Online: Commonly used antiemetics for prophylaxis of postoperative nausea and vomiting after Caesarean delivery with neuraxial morphine: a network meta-analysis.

Wang, Lizhong / Huang, Jiayue / Hu, Huijing / Chang, Xiangyang / Xia, Feng

British journal of anaesthesia

2024

Abstract: Background: Dopamine antagonists, 5-HT: Methods: We searched PubMed, Embase, CENTRAL, Web of Science, and Wanfang Data for eligible randomised controlled trials. Primary outcomes were the incidences of postoperative nausea (PON) and postoperative ... ...

Abstract	Background: Dopamine antagonists, 5-HT Methods: We searched PubMed, Embase, CENTRAL, Web of Science, and Wanfang Data for eligible randomised controlled trials. Primary outcomes were the incidences of postoperative nausea (PON) and postoperative vomiting (POV) within 24 h after surgery. We used a Bayesian random-effects model and calculated odds ratios with 95% credible intervals for dichotomous data. We performed sensitivity and subgroup analyses for primary outcomes. Results: A total of 33 studies with 4238 women were included. In the primary analyses of all women, 5-HT Conclusions: Combined 5-HT Systematic review protocol: PROSPERO CRD42023454602.
Language	English
Publishing date	2024-04-15
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	80074-0
ISSN	1471-6771 ; 0007-0912
ISSN (online)	1471-6771
ISSN	0007-0912
DOI	10.1016/j.bja.2024.03.010
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Article ; Online: Alteromonas salexigens sp. nov., isolated from coastal seawater.

Sun, Liping / Hu, Xinyuan / Wang, Qin / Niu, Huijing / Pei, Caixia / Li, Yi / Xia, Chengqiang

Archives of microbiology

2023 Volume 205, Issue 9, Page(s) 317

Abstract: A Gram-negative, aerobic, short rod-shaped bacterium, designated ASW11- ... ...

Abstract	A Gram-negative, aerobic, short rod-shaped bacterium, designated ASW11-19
MeSH term(s)	Alteromonas/genetics ; Phylogeny ; RNA, Ribosomal, 16S/genetics ; Fatty Acids ; DNA
Chemical Substances	RNA, Ribosomal, 16S ; Fatty Acids ; DNA (9007-49-2)
Language	English
Publishing date	2023-08-23
Publishing country	Germany
Document type	Journal Article
ZDB-ID	124824-8
ISSN	1432-072X ; 0302-8933
ISSN (online)	1432-072X
ISSN	0302-8933
DOI	10.1007/s00203-023-03658-x
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Article: A Cellular Senescence-Related Signature Predicts Cervical Cancer Patient Outcome and Immunotherapy Sensitivity.

Shao, Huijing / Li, Xia / Wu, Pengfei / Chen, Zixi / Zhang, Caihong / Gu, Hang

Research square

2023

Abstract: Cervical cancer (CC) is among the most prevalent gynaecological malignancy. The rate of mortality and morbidity of patients with CC is high. Cellular senescence is involved in tumorigenesis as well as cancer progression. However, the involvement of ... ...

Abstract	Cervical cancer (CC) is among the most prevalent gynaecological malignancy. The rate of mortality and morbidity of patients with CC is high. Cellular senescence is involved in tumorigenesis as well as cancer progression. However, the involvement of cellular senescence in CC development is still unclear and requires further investigation. We retrieved data on cellular senescence-related genes (CSRGs) from the "CellAge" Database. We used TCGA-CESC and the CGCI-HTMCP-CC datasets as the training and validation sets, respectively. Eight CSRGs signatures based on the data extracted from these sets were constructed using "univariate" and "Least Absolute Shrinkage and Selection Operator Cox regression analyses". Using this model, we calculated the risk scores of all patients in the training and validation cohort and categorised these patients into the low-risk group (LR-G) and the high-risk group (HR-G). Finally, compared to patients in the HR-G, CC patients in the LR-G demonstrated a more positive clinical prognosis; the expression of senescence-associated secretory phenotype (SASP) markers and immune cell infiltration was higher, and these patients had more active immune responses. In vitro studies showed increased SERPINE1 and IL-1α ((genes included in the signature) expression in CC cells and tissues. The eight-gene prognostic signatures could modulate the expression of SASP factors and the tumour immune micro-environment (TIME). It could be used as a reliable biomarker for predicting the patient's prognosis and response to immunotherapy in CC.
Language	English
Publishing date	2023-04-20
Publishing country	United States
Document type	Preprint
DOI	10.21203/rs.3.rs-2769887/v1
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Article ; Online: A Cellular Senescence-Related Signature Predicts Cervical Cancer Patient Outcome and Immunotherapy Sensitivity.

Shao, Huijing / Li, Xia / Wu, Pengfei / Chen, Zixi / Zhang, Caihong / Gu, Hang

Reproductive sciences (Thousand Oaks, Calif.)

2023 Volume 30, Issue 12, Page(s) 3661–3676

Abstract: Cervical cancer (CC) is one of the most prevalent gynecological malignancies. The rate of mortality and morbidity among patients with CC is high. Cellular senescence is involved in tumorigenesis as well as in the cancer progression. However, the ... ...

Abstract	Cervical cancer (CC) is one of the most prevalent gynecological malignancies. The rate of mortality and morbidity among patients with CC is high. Cellular senescence is involved in tumorigenesis as well as in the cancer progression. However, the involvement of cellular senescence in CC development is still unclear and requires further investigation. In this study, we retrieved data on cellular senescence-related genes (CSRGs) from the "CellAge" Database. We used the TCGA-CESC and CGCI-HTMCP-CC datasets as the training and validation sets, respectively. Finally, a signature was constructed using "univariate" and "Least Absolute Shrinkage and Selection Operator" (LASSO) Cox regression analysis, which contains eight CSRGs. Using this signature, we calculated the risk scores of all patients in the training and validation cohorts and categorized them into the low-risk group (LR-G) and the high-risk group (HR-G). Results showed that, compared to patients in the HR-G, those in the LR-G demonstrated a more positive clinical prognosis, more abundant immune cell infiltrations, and a more active immune response. The signature could also modulate the expression of SASP factors. In vitro studies showed an increased expression of SERPINE1 and IL-1α genes included in the signature in CC cells and tissues. Our findings help to deepen our insights into the etiology of CC, which could be beneficial for prognostic prediction and immunotherapy in clinical practice.
MeSH term(s)	Humans ; Female ; Uterine Cervical Neoplasms/genetics ; Uterine Cervical Neoplasms/therapy ; Cellular Senescence ; Immunotherapy ; Cell Transformation, Neoplastic ; Risk Factors ; Prognosis
Language	English
Publishing date	2023-08-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	2276411-2
ISSN	1933-7205 ; 1933-7191
ISSN (online)	1933-7205
ISSN	1933-7191
DOI	10.1007/s43032-023-01305-w
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Zs.A 4113: Show issues

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Article ; Online: Novel mitophagy inducer alleviates lupus nephritis by reducing myeloid cell activation and autoantigen presentation.

Wang, Huijing / Shen, Mingdi / Ma, Yanhong / Lan, Lan / Jiang, Xue / Cen, Xufeng / Guo, Gangqiang / Zhou, Qin / Yuan, Mengmeng / Chen, Jianghua / Xia, Hongguang / Xiao, Liang / Han, Fei

Kidney international

2024 Volume 105, Issue 4, Page(s) 759–774

Abstract: Lupus nephritis (LN) is one of the most severe manifestations of systemic lupus erythematosus (SLE), but its mechanism of onset remains unclear. Since impaired mitophagy has been implicated in multiple organs in SLE, we hypothesized that mitophagy ... ...

Abstract	Lupus nephritis (LN) is one of the most severe manifestations of systemic lupus erythematosus (SLE), but its mechanism of onset remains unclear. Since impaired mitophagy has been implicated in multiple organs in SLE, we hypothesized that mitophagy dysfunction is critical in the development of LN and that pharmacologically targeting mitophagy would ameliorate this disease. Therefore, lupus-prone MRL/MpJ-Fas
MeSH term(s)	Humans ; Mice ; Animals ; Lupus Nephritis/pathology ; Autoantigens ; Mitophagy ; Mice, Inbred MRL lpr ; Lupus Erythematosus, Systemic ; Kidney/pathology ; Myeloid Cells ; Inflammation/pathology ; Sulfonamides ; Thioglycolates
Chemical Substances	UMI-77 ; Autoantigens ; Sulfonamides ; Thioglycolates
Language	English
Publishing date	2024-01-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	120573-0
ISSN	1523-1755 ; 0085-2538
ISSN (online)	1523-1755
ISSN	0085-2538
DOI	10.1016/j.kint.2023.12.017
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Article: Active and Passive Immunization with an Anti-Methamphetamine Vaccine Attenuates the Behavioral and Cardiovascular Effects of Methamphetamine.

Haile, Colin N / Varner, Kurt J / Huijing, Xia / Arora, Reetakshi / Orson, Frank M / Kosten, Thomas R / Kosten, Therese A

Vaccines

2022 Volume 10, Issue 9

Abstract: Background: Methamphetamine use disorder (MUD) is a growing health concern with no FDA-approved treatment. The present series of studies build upon our previous work developing an anti-methamphetamine (MA) vaccine for MUD. We determined the effects of a ...

Abstract	Background: Methamphetamine use disorder (MUD) is a growing health concern with no FDA-approved treatment. The present series of studies build upon our previous work developing an anti-methamphetamine (MA) vaccine for MUD. We determined the effects of a formulation that included tetanus-toxoid (TT) conjugated to succinyl-methamphetamine (TT-SMA) adsorbed onto aluminum hydroxide (alum) in combination with the novel Toll-Like Receptor-5 agonist, entolimod. Methods: Mice were vaccinated (0, 3, 6 weeks) with TT-SMA+alum and various doses of entolimod to determine an optimal dose for enhancing immunogenicity against MA. Functional effects were then assessed using MA-induced locomotor activation in mice. Experiments using passive immunization of antibodies generated by the vaccine tested its ability to attenuate MA-induced cardiovascular effects and alter the reinforcing effects of MA in an MA-induced reinstatement of a drug seeking model of relapse in male and female rats. Results: Antibody levels peaked at 10 weeks following vaccination with TT-SMA+alum combined with entolimod (1, 3 and 10 μg). MA-induced locomotor activation was significantly attenuated in vaccinated vs. unvaccinated mice and antibody levels significantly correlated with ambulation levels. Passive immunization decreased mean arterial pressure following MA dosing in rats of both sexes but did not alter heart rate. Passive immunization also attenuated the ability of MA to reinstate extinguished drug-seeking behavior in male and female rats. Results support further development of this vaccine for relapse prevention for individuals with MUD.
Language	English
Publishing date	2022-09-09
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2703319-3
ISSN	2076-393X
ISSN	2076-393X
DOI	10.3390/vaccines10091508
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Article ; Online: The normative values of vertical jump and sit-and-reach in a large general Chinese population aged 8–80 years

Huijing He / Li Pan / Dingming Wang / Jianwei Du / Lize Pa / Hailing Wang / Jingbo Zhao / Xia Peng / Guangliang Shan

Global Transitions, Vol 5, Iss , Pp 141-

The China National Health Survey

2023 Volume 148

Abstract: The normative values of vertical jump (VJ) and sit-and-reach (SR) for Chinese people are still unclear. We aimed to determine these values and their correlations with body composition using data from China National Health Survey which included 19,269 ... ...

Abstract	The normative values of vertical jump (VJ) and sit-and-reach (SR) for Chinese people are still unclear. We aimed to determine these values and their correlations with body composition using data from China National Health Survey which included 19,269 participants aged 8–80 years. Sex-specific smoothed centile tables were generated for the P1, P5, P25, P50, P75, P95, and P99 centiles of VJ and SR using lambda-mu-sigma method. The median (Interquartile range) values of VJ and SR in males and females were as follows: 20.3 (8.8) cm and 14.1 (5.5) cm for VJ, 1.8 (11.6) cm and 6.8 (10.4) cm for SR, respectively. In males, VJ values increased to a peak around the age of 18, with the 5th and 95th values being 17.7 cm and 41.3 cm, respectively. After reaching the peak, VJ values gradually declined with age. In females, VJ values remained relatively stable from childhood to early adulthood, and then declined after the age of 30. The peak values of SR were observed in early adulthood in both sexes, and remained stable in females but declined with age in males. VJ had a negative association with body composition, particularly in females. SR was found to have a negative association with fat mass indexes in males. However, correlations in females were only marginally statistically significant. The study provides age- and sex-specific percentile reference values for VJ and SR in Chinese people and can aid in the assessment of muscle fitness and facilitate early prediction of neuromuscular disorders.
Keywords	Muscle function ; Physical fitness ; Body composition ; Normative value ; Technology ; T ; Medicine ; R
Subject code	796
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	KeAi Communications Co., Ltd.
Document type	Article ; Online
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Article ; Online: From Triboelectric Nanogenerator to Multifunctional Triboelectric Sensors: A Chemical Perspective toward the Interface Optimization and Device Integration.

Xiang, Huijing / Zeng, Yuanming / Huang, Xiaomin / Wang, Ning / Cao, Xia / Wang, Zhong Lin

Small (Weinheim an der Bergstrasse, Germany)

2022 Volume 18, Issue 43, Page(s) e2107222

Abstract: Triboelectric nanogenerators (TENGs) have intrigued scientists for their potential to alleviate the energy shortage crisis and facilitate self-powered sensors. Triboelectric interfaces containing triboelectric functionalized molecular groups and tunable ... ...

Abstract	Triboelectric nanogenerators (TENGs) have intrigued scientists for their potential to alleviate the energy shortage crisis and facilitate self-powered sensors. Triboelectric interfaces containing triboelectric functionalized molecular groups and tunable surface charge densities are important for improving the electrical output capability of TENGs and the versatility of future electronics. In this review, following an introduction to the fundamental progress of TENG systems for mechanic energy harvesting, surface modifications that aim to increase the surface charge density and functionality are highlighted, with an emphasis on interfacial chemical modification and triboelectric energetics/dynamics optimization for efficient electrostatic induction and charge transfer. Recent advances in assemblies of multifunctional triboelectric sensing are briefly introduced, and future challenges and chemical perspectives in the field of TENG-based electronics are concisely reviewed. This review presents and advances the understanding of the state-of-the-art chemical strategies toward rational triboelectric interface engineering and system assembly and is expected to guide the rational design of highly efficient and versatile triboelectric sensing.
MeSH term(s)	Nanotechnology ; Electronics ; Electric Power Supplies ; Electricity
Language	English
Publishing date	2022-09-19
Publishing country	Germany
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2168935-0
ISSN	1613-6829 ; 1613-6810
ISSN (online)	1613-6829
ISSN	1613-6810
DOI	10.1002/smll.202107222
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Article ; Online: Case Management Improves Satisfaction, Anxiety, and Depression of Patients with Pregnancy Loss after In Vitro Fertilization and Embryo Transfer.

Wu, Xiangli / Wu, Yidan / Xia, Mei / Xie, Wenjie / Hu, Huijing / Xiao, Zhen / Xu, Weihai / Shu, Jing

publication RETRACTED

Computational and mathematical methods in medicine

2022 Volume 2022, Page(s) 1968313

Abstract: Objective: Pregnancy loss has negative impacts on both the physical and the mental health of expectant mothers, which calls for an in-depth investigation. In this study, we examined the effects of case management on patients with pregnancy loss after in ...

Abstract	Objective: Pregnancy loss has negative impacts on both the physical and the mental health of expectant mothers, which calls for an in-depth investigation. In this study, we examined the effects of case management on patients with pregnancy loss after in vitro fertilization and embryo transfer (IVF-ET). Methods: 100 participants that had suffered pregnancy loss after IVF-ET-assisted pregnancy from January 2019 to March 2020 were divided into routine care and case management groups, each with 50 cases. For the routine care group, a doctor led the diagnostic and treatment processes and a nurse assisted with the treatment. For the case management group, a nurse led the patient diagnostic and treatment processes and a doctor controlled the diagnosis and treatment plan formulation. Case management models were established according to the comprehensive peripregnancy loss care of patients with pregnancy loss after IVF-ET-assisted pregnancy. The participants' outcomes (satisfaction, anxiety, and depression) were assessed at the time of pregnancy loss and 1 and 3 months after pregnancy loss during follow-up of the routine care and case management groups. Results: There was no statistical difference between the patients in the two groups with regard to their general information statistics ( Conclusion: Case management care can have a positive effect on improving the satisfaction, anxiety, and depression of patients that have had pregnancy loss after IVF-ET.
MeSH term(s)	Anxiety/etiology ; Anxiety/therapy ; Case Management ; Embryo Transfer/psychology ; Female ; Fertilization in Vitro/psychology ; Humans ; Patient Satisfaction ; Personal Satisfaction ; Pregnancy
Language	English
Publishing date	2022-04-07
Publishing country	United States
Document type	Journal Article ; Retracted Publication
ZDB-ID	2252430-7
ISSN	1748-6718 ; 1748-670X ; 1027-3662
ISSN (online)	1748-6718
ISSN	1748-670X ; 1027-3662
DOI	10.1155/2022/1968313
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