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Article ; Online: Cephalic arch stenosis: an analysis of outcome by type of first intervention.

Pisano, Umberto / Stevenson, Karen / Kasthuri, Ram / Kingsmore, David

CVIR endovascular

2024 Volume 7, Issue 1, Page(s) 13

Abstract: Background: Cephalic arch stenoses (CAS) occur in near 70% of elbow arteriovenous fistulas. Percutaneous transluminal angioplasty (PTA) remains first-line treatment despite documented stent-grafts (SG) efficacy. The study aim is to report long-term ... ...

Abstract	Background: Cephalic arch stenoses (CAS) occur in near 70% of elbow arteriovenous fistulas. Percutaneous transluminal angioplasty (PTA) remains first-line treatment despite documented stent-grafts (SG) efficacy. The study aim is to report long-term outcomes based on initial treatment of CAS. Methods: Retrospective review of 12-year data in single tertiary centre. Outcomes included technical success, rupture rate, primary patency (PP), dialysis performance; categorical variables assessed via χ Results: One hundred one brachio- and radiocephalic fistulas with CAS were included. SG as first intervention had higher success than PTA (85% vs 61%, p = 0.003). Rupture occurred in 9/85 (10.6%) PTA vs 0% in SG (p = 0.046). In a subgroup with poor urea reduction rate (URR), both PTA and SG improved dialysis performance post-intervention (p = 0.002). SG demonstrated better PP than PTA (79,73,60% patency at 3, 6, 9 months; versus 71,51,47%; p = 0.195) and cumulative patency (73,61,61% at 1, 2, 3 years; versus 60,34,26%; p < 0.001). Of the variables analyzed, technical success of PTA was the only discriminating factor (coeff.-1.01; RR 35%, p = 0.035). Accesses that underwent secondary stenting performed better than primarily stented CAS (p = 0.01). Conclusions: SG superiority is confirmed in CAS, particularly when angioplasty is unsuccessful. While PTA has short-lived benefits, it can improve dialysis performance. Other than higher success rate, primary CAS stenting did not have advantages compared to post-PTA stenting in our study. Other factors related to inflow, outflow, conduit characteristics are presumed to be involved in access longevity.
Language	English
Publishing date	2024-01-19
Publishing country	Switzerland
Document type	Journal Article
ISSN	2520-8934
ISSN (online)	2520-8934
DOI	10.1186/s42155-023-00424-4
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Corona mortis injury causing delayed presentation of pelvic pseudoaneurysm.

Pisano, Umberto / Soon, V-Liem / Douglas, Peter

Radiology case reports

2021 Volume 16, Issue 5, Page(s) 1095–1098

Abstract: Pseudoaneurysms are rare complications in urological surgery. Typically, they would present with pain, haematuria or anaemia. We report a 60-year-old patient who was found to have a chronic pseudoaneurysm via a corona mortis vascular variant, 3 months ... ...

Abstract	Pseudoaneurysms are rare complications in urological surgery. Typically, they would present with pain, haematuria or anaemia. We report a 60-year-old patient who was found to have a chronic pseudoaneurysm via a corona mortis vascular variant, 3 months after a robotic-assisted prostatectomy. Unlike other rare reports of delayed vascular complications after minimally invasive urological surgery, the patient was entirely asymptomatic.Apart from careful intraoperative dissection, a high index of suspicion and low threshold for imaging are also required in the follow up period. Percutaneous trans-arterial embolization is safe and effective in dealing with post-surgical pseudoaneurysms.
Language	English
Publishing date	2021-02-24
Publishing country	Netherlands
Document type	Case Reports
ZDB-ID	2406300-9
ISSN	1930-0433
ISSN	1930-0433
DOI	10.1016/j.radcr.2021.02.017
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Article: Oxidative Stress in the Pathogenesis of Aorta Diseases as a Source of Potential Biomarkers and Therapeutic Targets, with a Particular Focus on Ascending Aorta Aneurysms.

Pisano, Calogera / Benedetto, Umberto / Ruvolo, Giovanni / Balistreri, Carmela Rita

Antioxidants (Basel, Switzerland)

2022 Volume 11, Issue 2

Abstract: Aorta diseases, such as ascending aorta aneurysm (AsAA), are complex pathologies, currently defined as inflammatory diseases with a strong genetic susceptibility. They are difficult to manage, being insidious and silent pathologies whose diagnosis is ... ...

Abstract	Aorta diseases, such as ascending aorta aneurysm (AsAA), are complex pathologies, currently defined as inflammatory diseases with a strong genetic susceptibility. They are difficult to manage, being insidious and silent pathologies whose diagnosis is based only on imaging data. No diagnostic and prognostic biomarkers or markers of outcome have been known until now. Thus, their identification is imperative. Certainly, a deep understanding of the mechanisms and pathways involved in their pathogenesis might help in such research. Recently, the key role of oxidative stress (OS) on the pathophysiology of aorta disease has emerged. Here, we describe and discuss these aspects by revealing some OS pathways as potential biomarkers, their underlying limitations, and potential solutions and approaches, as well as some potential treatments.
Language	English
Publishing date	2022-01-18
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2704216-9
ISSN	2076-3921
ISSN	2076-3921
DOI	10.3390/antiox11020182
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Article: Oxidative Stress in the Pathogenesis of Aorta Diseases as a Source of Potential Biomarkers and Therapeutic Targets, with a Particular Focus on Ascending Aorta Aneurysms

Pisano, Calogera / Benedetto, Umberto / Ruvolo, Giovanni / Balistreri, Carmela Rita

Antioxidants. 2022 Jan. 18, v. 11, no. 2

2022

Abstract	Aorta diseases, such as ascending aorta aneurysm (AsAA), are complex pathologies, currently defined as inflammatory diseases with a strong genetic susceptibility. They are difficult to manage, being insidious and silent pathologies whose diagnosis is based only on imaging data. No diagnostic and prognostic biomarkers or markers of outcome have been known until now. Thus, their identification is imperative. Certainly, a deep understanding of the mechanisms and pathways involved in their pathogenesis might help in such research. Recently, the key role of oxidative stress (OS) on the pathophysiology of aorta disease has emerged. Here, we describe and discuss these aspects by revealing some OS pathways as potential biomarkers, their underlying limitations, and potential solutions and approaches, as well as some potential treatments.
Keywords	aneurysm ; aorta ; biomarkers ; oxidative stress ; pathogenesis ; pathophysiology ; therapeutics
Language	English
Dates of publication	2022-0118
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2704216-9
ISSN	2076-3921
ISSN	2076-3921
DOI	10.3390/antiox11020182
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Corona mortis injury causing delayed presentation of pelvic pseudoaneurysm

Umberto Pisano, MD, MSc, MRCS, FRCR / V-Liem Soon, MBChB, FRCR / Peter Douglas, MBChB, MRCP, FRCR

Radiology Case Reports, Vol 16, Iss 5, Pp 1095-

2021 Volume 1098

Abstract	Pseudoaneurysms are rare complications in urological surgery. Typically, they would present with pain, haematuria or anaemia. We report a 60-year-old patient who was found to have a chronic pseudoaneurysm via a corona mortis vascular variant, 3 months after a robotic-assisted prostatectomy. Unlike other rare reports of delayed vascular complications after minimally invasive urological surgery, the patient was entirely asymptomatic.Apart from careful intraoperative dissection, a high index of suspicion and low threshold for imaging are also required in the follow up period. Percutaneous trans-arterial embolization is safe and effective in dealing with post-surgical pseudoaneurysms.
Keywords	Corona Mortis ; Robotic Prostatectomy ; Pseudoaneurysm ; Embolization ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
Language	English
Publishing date	2021-05-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Leadless transcatheter pacemaker: Indications, implantation technique and peri-procedural patient management in the Italian clinical practice.

Palmisano, Pietro / Iacopino, Saverio / De Vivo, Stefano / D'Agostino, Carlo / Tomasi, Luca / Startari, Umberto / Ziacchi, Matteo / Pisanò, Ennio Carmine Luigi / Santobuono, Vincenzo Ezio / Caccavo, Vincenzo Paolo / Sgarito, Giuseppe / Rillo, Mariano / Nicosia, Antonino / Zucchelli, Giulio

International journal of cardiology

2022 Volume 365, Page(s) 49–56

Abstract: Background: Safety and efficacy of leadless pacemakers (L-PM) have been demonstrated in multiple clinical trials, but real-world data on patient selection, implantation technique, and peri-procedural patient management in a clinical practice setting are ...

Abstract	Background: Safety and efficacy of leadless pacemakers (L-PM) have been demonstrated in multiple clinical trials, but real-world data on patient selection, implantation technique, and peri-procedural patient management in a clinical practice setting are lacking. Methods: Consecutive patients undergoing L-PM implantation in 14 Italian centers were followed in a prospective, multicentre, observational project. Data on baseline patient characteristics, clinical indications, implantation procedure, and peri-procedural patient management were collected. The rate and nature of device-related complications were also recorded. Results: A total of 782 L-PM patients (68.4% male, 75.6 ± 12.4 years) were included in the analysis. The main patients-related reason leading to the choice of implanting a L-PM rather than a conventional PM was the high-risk of device infection (29.5% of cases). The implantation success rate was 99.2%. The median duration of the procedure was 46 min. In 90% of patients the device was implanted in the septum. Of patients on oral anticoagulant therapy (OAT) (n = 498) the implantation procedure was performed without interrupting (17.5%) or transiently interrupting OAT without heparin bridging (60.6%). During a median follow-up of 20 months major device-related complications occurred in 7 patients (0.9%): vascular access-site complications in 3 patients, device malfunction in 2 patients, pericardial effusion/cardiac tamponade in one patient, device migration in one patient. Conclusions: In the real world setting of Italian clinical practice L-PM is often reserved for patients at high-risk of infection. The implantation success rate was very high and the risk of major complications was low. Peri-procedural management of OAT was consistent with available scientific evidence.
MeSH term(s)	Equipment Design ; Female ; Humans ; Male ; Pacemaker, Artificial/adverse effects ; Pericardial Effusion/etiology ; Prospective Studies ; Time Factors ; Treatment Outcome
Language	English
Publishing date	2022-07-28
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	779519-1
ISSN	1874-1754 ; 0167-5273
ISSN (online)	1874-1754
ISSN	0167-5273
DOI	10.1016/j.ijcard.2022.07.040
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Article ; Online: Small bowel transanal evisceration mimicking a rectal prolapse. A case report and review of literature.

Pisano, Giuseppe / Erdas, Enrico / Medas, Fabio / Pisano, Umberto / Calò, Pietro Giorgio

Annali italiani di chirurgia

2017 Volume 6

Abstract: Transanal intestinal evisceration is a very uncommon and dramatic occurrence, linked most frequently to rectal prolapse rupture or, very rarely, to traumatic pathology. The Authors describe a case of a 74-year-old female patient who required urgent ... ...

Abstract	Transanal intestinal evisceration is a very uncommon and dramatic occurrence, linked most frequently to rectal prolapse rupture or, very rarely, to traumatic pathology. The Authors describe a case of a 74-year-old female patient who required urgent hospital admission because of a seemingly strangulated rectal prolapse. During surgical preparation the protruding mass was recognized as small bowel loops herniating from the anus. Evisceration was due to spontaneous rectal wall rupture, most likely caused by increased abdominal pressure and consequent breach through the weakened rectum. Surgical treatment consisted in small bowel resection combined with an Hartmann's procedure. Spontaneous rectal rupture without a pre-existing rectal prolapse is a rather infrequent and challenging condition; its mechanism is still incompletely explained. The management is surgical and may range from primary repair up to extensive intestinal resection to include a defunctioning colostomy. Key words: Rectal prolapse, Spontaneous rectal rupture, Transanal evisceration.
MeSH term(s)	Aged ; Anal Canal ; Diagnostic Errors ; Emergencies ; Female ; Humans ; Jejunum ; Rectal Diseases/diagnosis ; Rectal Diseases/surgery ; Rectal Prolapse/diagnosis ; Rupture, Spontaneous
Language	English
Publishing date	2017-11-20
Publishing country	Italy
Document type	Case Reports ; Journal Article ; Review
ZDB-ID	418927-9
ISSN	2239-253X ; 0003-469X
ISSN (online)	2239-253X
ISSN	0003-469X
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Article ; Online: Azimuthal asymmetries in p↑p → jet π X

Pisano Cristian / D’Alesio Umberto / Murgia Francesco

EPJ Web of Conferences, Vol 85, p

2015 Volume 02032

Abstract: We study the azimuthal asymmetries for the distributions of leading pions inside a jet produced inclusively in high-energy proton-proton collisions within the framework of the transverse momentum dependent generalized parton model. We present results for ...

Abstract	We study the azimuthal asymmetries for the distributions of leading pions inside a jet produced inclusively in high-energy proton-proton collisions within the framework of the transverse momentum dependent generalized parton model. We present results for the RHIC center-of-mass energies √s = 200 and 500 GeV, mainly for forward jet rapidities, in particular for the two mechanisms which dominate such asymmetries: the Sivers and the Collins effects. We also briefly discuss the case of inclusive jet production and, adopting the socalled colour gauge invariant parton model, we propose a phenomenological analysis of the process dependence of the quark Sivers function.
Keywords	Physics ; QC1-999 ; Science ; Q
Language	English
Publishing date	2015-01-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Grossly delayed massive subcutaneous emphysema following laparoscopic left hemicolectomy: A case report.

Jones, Angharad / Pisano, Umberto / Elsobky, Sherif / Watson, Angus J M

International journal of surgery case reports

2014 Volume 6C, Page(s) 277–279

Abstract: Introduction: Surgical emphysema is a known early complication of laparoscopic surgery, common during upper gastrointestinal and gynaecological surgery; the authors present the first case of delayed subcutaneous emphysema following a laparoscopic left ... ...

Abstract	Introduction: Surgical emphysema is a known early complication of laparoscopic surgery, common during upper gastrointestinal and gynaecological surgery; the authors present the first case of delayed subcutaneous emphysema following a laparoscopic left hemicolectomy. Presentation of case: A 52-year-old woman underwent a laparoscopic left hemicolectomy for a sigmoid malignancy; on the third post-operative day after an uneventful procedure, she developed a massive surgical emphysema involving her face, neck and chest with associated pneumoperitoneum but without any evidence of pneumothorax. A gastrograffin enema ruled out an anastomotic leak. Apart from a borderline tachycardia, mildly low saturations and an area of erythema in her right flank, she was totally asymptomatic. The emphysema resolved spontaneously around the 6th post-operative day. Discussion: Massive subcutaneous surgical emphysema after laparoscopic colorectal surgery is a rare complication and can me managed conservatively with a good outcome. Conclusion: To our knowledge, this represents the first case of delayed massive surgical emphysema following colorectal surgery, the aetiology of which has still not been clearly explained, after exclusion of the most common causes.
Language	English
Publishing date	2014-12-02
Publishing country	Netherlands
Document type	Journal Article
ISSN	2210-2612
ISSN	2210-2612
DOI	10.1016/j.ijscr.2014.10.007
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Bridging the science-policy gap

Michal Sedlacko / Umberto Pisano / Gerald Berger / Katrin Lepuschitz

Sustainability: Science, Practice, & Policy, Vol 9, Iss 2, Pp 105-

development and reception of a joint research agenda on sustainable food consumption

2013 Volume 123

Abstract: To increase the uptake of research findings by policy makers and to encourage European researchers to better reflect policy needs, we facilitated the development of a joint research agenda (JRA) on sustainable food consumption (SFC) involving scientists, ...

Abstract	To increase the uptake of research findings by policy makers and to encourage European researchers to better reflect policy needs, we facilitated the development of a joint research agenda (JRA) on sustainable food consumption (SFC) involving scientists, policy makers, and other stakeholders. Pursuing interpretive action research and using a number of data sources, we tried to understand how the “fit” between the characteristics of policy makers’ organizational contexts and the attributes of the JRA development process affects the reception of the JRA and its outcomes. Our framework was based on three distinct formations of discursive and material practices related to the use of knowledge in public policy making: bureaucratic, managerial, and communicative. Two dominant patterns seem to be represented in SFC consumption in the European Union: a transition between the bureaucratic and the managerial formation and a highly developed managerial formation with occasional communicative practices. We found that reflecting national policy priorities would help overcome some of the structural barriers between science and policy, whereas other barriers could be addressed by designing the process to better fit with the logics of the three formations, such as the fragmentation of knowledge (bureaucratic formation) or breadth of participation (communicative formation).
Keywords	policy research ; workshops ; food consumption ; participatory planning ; stakeholders ; Social sciences (General) ; H1-99
Subject code	360 ; 320
Language	English
Publishing date	2013-10-01T00:00:00Z
Publisher	Taylor & Francis Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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