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  1. Book: Der Briefwechsel mit Antoine Arnauld

    Leibniz, Gottfried Wilhelm / Arnauld, Antoine / Finster, Reinhard

    französisch - deutsch

    (Philosophischer Briefwechsel ; / Gottfried Wilhelm Leibniz ; Bd. 1)

    1997  

    Author's details Gottfried Wilhelm Leibniz. Hrsg. und übers. von Reinhard Finster
    Series title Philosophischer Briefwechsel
    / Gottfried Wilhelm Leibniz ; Bd. 1
    Language French ; German
    Size XL, 431 S., 25 cm
    Publisher Meiner
    Publishing place Hamburg
    Document type Book
    Note Alle Briefe dt. und franz., Vorw., Einl. und editorischer Bericht dt.
    ISBN 3787310916 ; 9783787310913
    Database Former special subject collection: coastal and deep sea fishing

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  2. Article: Minimally Invasive Endoscopic Sinus Surgery for Frontal Sinus Pathologies Using Interventional Flexible Bronchoscopy: Case Reports.

    Litzistorf, Yann / Gorostidi, François / Reinhard, Antoine

    Allergy & rhinology (Providence, R.I.)

    2021  Volume 12, Page(s) 21526567211030889

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2021-09-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2675684-5
    ISSN 2152-6567 ; 2152-6575
    ISSN (online) 2152-6567
    ISSN 2152-6575
    DOI 10.1177/21526567211030889
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  3. Article ; Online: Utility of flexible interventional endoscopy in endoscopic sinus surgery: a case series.

    Litzistorf, Yann / Gorostidi, François / Lambercy, Karma / Reinhard, Antoine

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2022  Volume 280, Issue 3, Page(s) 1231–1239

    Abstract: Purpose: During endoscopic sinus surgery (ESS), difficult-to-reach pathologies need an extended endoscopic approach or an external approach. We started to use a flexible interventional endoscope (FIE) to evaluate the necessity of those approaches. The ... ...

    Abstract Purpose: During endoscopic sinus surgery (ESS), difficult-to-reach pathologies need an extended endoscopic approach or an external approach. We started to use a flexible interventional endoscope (FIE) to evaluate the necessity of those approaches. The study's objective is to describe our experience and define patients who could benefit from this technique.
    Methods: We reviewed every patient who benefited from FIE associated with ESS at our tertiary University Hospital between January 2021 and February 2022.
    Results: During this period, we did 107 ESS, and 14 patients benefited from the FIE, representing 13% of our ESS. The median duration of the flexible endoscopy time was 14 min (4-38 min). We identified three groups of patients who can benefit from the FIE. The first one is for patients with a fungal infection, to control and to clean lateral recesses in a noninvasive manner. The second one is for patients with a pathology of the lateral frontal sinus, to remove the frontoethmoidal cells or mucocele with the biopsy forceps through the working channel. The third group is for patients with inverted papillomas, to precisely identify the insertion and to decide on the most appropriate surgical approach.
    Conclusions: In selected cases, using flexible endoscopy during ESS helps decide the optimal surgical approach and sometimes treat the pathology through a limited approach. Prospective studies for each group of patients are needed to confirm the benefit of this new combined procedure.
    MeSH term(s) Humans ; Endoscopy/methods ; Frontal Sinus/diagnostic imaging ; Frontal Sinus/surgery ; Frontal Sinus/pathology ; Mucocele/pathology ; Mucocele/surgery ; Papilloma, Inverted/diagnostic imaging ; Papilloma, Inverted/surgery ; Papilloma, Inverted/pathology ; Prospective Studies ; Retrospective Studies
    Language English
    Publishing date 2022-09-22
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-022-07655-6
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  4. Article: Allergologie-immunologie - Rhinosinusite chronique avec polypes nasaux : quelle est la place des anticorps monoclonaux en 2020 ?

    Clottu, Aurélie / Reinhard, Antoine / Comte, Denis

    Revue medicale suisse

    2021  Volume 17, Issue 720-1, Page(s) 13–17

    Abstract: Chronic rhinosinusitis with nasal polyps is a severe form of chronic rhinosinusitis, which has a strong negative impact on quality of life. Rhinoscopy is helpful for diagnosis, and initial management depends on intra-nasal corticosteroids and sometimes ... ...

    Title translation Chronic rhinosinusitis with nasal polyps : is there a place for monoclonal antibodies in 2020 ?
    Abstract Chronic rhinosinusitis with nasal polyps is a severe form of chronic rhinosinusitis, which has a strong negative impact on quality of life. Rhinoscopy is helpful for diagnosis, and initial management depends on intra-nasal corticosteroids and sometimes short-term oral corticosteroids (1 to 3 weeks). If well-conducted drug therapy fails, surgery is considered. In the event of post-surgery recurrence or in case of concomitant severe asthma, biologic therapies represent an interesting option. These drugs include dupilumab, mepolizumab, benralizumab and omalizumab. The choice of medication depends on the individual patient context, which includes the presence of atopic dermatitis, eosinophilia, or asthma.
    MeSH term(s) Antibodies, Monoclonal/therapeutic use ; Chronic Disease ; Humans ; Nasal Polyps/complications ; Nasal Polyps/drug therapy ; Quality of Life ; Rhinitis/complications ; Rhinitis/drug therapy ; Sinusitis/complications ; Sinusitis/drug therapy
    Chemical Substances Antibodies, Monoclonal
    Language French
    Publishing date 2021-01-14
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A Combined Surgical Approach for the Treatment of a Sino-Naso-Orbital Glomangiopericytoma

    Ania Labouchère / Cécile De Sandre / Martin Broome / Antoine Reinhard / Aurélien Louvrier

    Reports, Vol 6, Iss 7, p

    2023  Volume 7

    Abstract: Glomangiopericytomas are a rare type of sinonasal tumors with high relapse rates. Endoscopic sinus surgery is the classical technique to remove such tumors. Here we report a case of sinonasal glomangiopericytoma with orbital extension, infrequently ... ...

    Abstract Glomangiopericytomas are a rare type of sinonasal tumors with high relapse rates. Endoscopic sinus surgery is the classical technique to remove such tumors. Here we report a case of sinonasal glomangiopericytoma with orbital extension, infrequently described in the literature. A 50 year-old woman was referred to our hospital because of a right paranasal painless swelling, which appeared 9 months ago and was slowly increasing in size since her first visit. A Magnetic Resonance Imaging (MRI) revealed a tumor (18 × 25 × 37 mm) centered on the right ethmoidal cells, with adjacent nasal bone erosion and a right orbital invasion. The tumor was removed with a combined surgical approach (endoscopic and trans-sinusal frontal approach) after pre-surgical embolization. Based on the results of the histopathological examination, the diagnosis of a glomangiopericytoma was confirmed. The patient was discharged after one week, and an uneventful long-term follow-up.
    Keywords glomangiopericytoma ; endoscopy ; ENT surgery ; maxillo-facial surgery ; Medicine (General) ; R5-920 ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Subject code 616
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Three-Dimensional Printed Nasal Prostheses After Oncologic Rhinectomies: Workflow and Patients' Satisfaction.

    Salati, Victoria / Reinhard, Antoine / Broome, Martin

    The Journal of craniofacial surgery

    2021  Volume 32, Issue 7, Page(s) 2297–2300

    Abstract: Abstract: Reconstructions after oncologic full-thickness rhinectomies are often deferred from the ablative surgery. Definitive silicone prostheses are usually not used for transitional rehabilitation, and therefore, patients may deal with major facial ... ...

    Abstract Abstract: Reconstructions after oncologic full-thickness rhinectomies are often deferred from the ablative surgery. Definitive silicone prostheses are usually not used for transitional rehabilitation, and therefore, patients may deal with major facial defects for a long time before reconstruction. The aim was to develop a time- and cost-effective digital workflow to three-dimensional print temporary nasal prostheses and to assess patients' satisfaction. This prospective study enrolled all consecutive patients after full thickness ablative surgery and deferred reconstruction, from May 2018 to October 2019, at a tertiary care academic institution. With a dedicated software, the pre- and postoperative scans were three-dimensional processed to create the prosthesis and they were directly printed in elastic transparent resin. A cross-sectional survey was conducted 4 months after the rehabilitation to assess patients' satisfaction regarding comfort, aesthetics, and security of the retaining system. Seven patients were enrolled and they were all rehabilitated using this workflow. Mean time of design was 2h48 (SD 40 minutes), and mean printing time was 5h18 (SD 1 hour). Mean cost of production was 753 U.S. Dollars (SD 144 U.S. Dollars). Median scores of the visual analog scales were 8 out of 10 for each topic with interquartile range of 4 to 7 for aesthetics, 7 to 9 for comfort, and 7 to 10 for security of the retaining system. It has shown its feasibility in terms of costs and time of production. Patients were satisfied and it can be considered as a mean to help patients to deal with treatment sequelaes before definitive reconstruction.
    MeSH term(s) Cross-Sectional Studies ; Dental Implants ; Esthetics, Dental ; Humans ; Patient Satisfaction ; Printing, Three-Dimensional ; Prospective Studies ; Prostheses and Implants ; Prosthesis Design ; Workflow
    Chemical Substances Dental Implants
    Language English
    Publishing date 2021-04-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1159501-2
    ISSN 1536-3732 ; 1049-2275
    ISSN (online) 1536-3732
    ISSN 1049-2275
    DOI 10.1097/SCS.0000000000007659
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Mucosal Melanoma of the Head and Neck: A Retrospective Review and Current Opinion.

    Pincet, Laurence / Lambercy, Karma / Pasche, Philippe / Broome, Martin / Latifyan, Sofiya / Reinhard, Antoine

    Frontiers in surgery

    2021  Volume 7, Page(s) 616174

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2021-01-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2773823-1
    ISSN 2296-875X
    ISSN 2296-875X
    DOI 10.3389/fsurg.2020.616174
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  8. Article: Atteintes ORL liées au Covid : prise en charge aiguë et enjeux de la stratégie rééducative.

    Ishii, Alessandro / Reinhard, Antoine / Simon, Christian / Schweizer, Valérie / Todic, Jelena

    Revue medicale suisse

    2021  Volume 17, Issue 753, Page(s) 1681–1683

    Abstract: The ENT specialist manages patients with SARS-CoV-2 infection in the acute phase as well as in the long-term sequelae. Acute management includes evaluation of patients with prolonged orotracheal intubation, surgical tracheostomies and monitoring of their ...

    Title translation COVID-related ENT affections: acute management and issues of rehabilitation strategy.
    Abstract The ENT specialist manages patients with SARS-CoV-2 infection in the acute phase as well as in the long-term sequelae. Acute management includes evaluation of patients with prolonged orotracheal intubation, surgical tracheostomies and monitoring of their weaning as well as airway assessment. Long-term sequelae include olfactory disorders, upper airway damage, laryngeal damage and their functional consequences : dyspnea, dysphonia and dysphagia. ENT symptoms after SARS-CoV-2 infection have an impact on patients' morbidity and quality of life. We created an ENT Task Force at the CHUV to better organize medical management. This article summarizes the main points.
    MeSH term(s) COVID-19 ; Humans ; Quality of Life ; SARS-CoV-2
    Language French
    Publishing date 2021-10-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Anosmie et COVID-19.

    Reinhard, Antoine / Ikonomidis, Christos / Broome, Martin / Gorostidi, François

    Revue medicale suisse

    2020  Volume 16, Issue N° 691-2, Page(s) 849–851

    Abstract: Anosmia associated or not with dysgeusia seems to be a frequent symptom in cases of infection with SARS-CoV-2 responsible for COVID-19. It can be the initial symptom of the disease or remain isolated in pauci-symptomatic patients. Waiting for scientific ... ...

    Title translation Anosmia and COVID-19.
    Abstract Anosmia associated or not with dysgeusia seems to be a frequent symptom in cases of infection with SARS-CoV-2 responsible for COVID-19. It can be the initial symptom of the disease or remain isolated in pauci-symptomatic patients. Waiting for scientific confirmation and in the context of the current pandemic, it seems essential to consider any patient with a new anosmia as being infected with SARS-CoV-2 until proven otherwise. These patients should therefore isolate themselves and remain alert to the occurrence of other symptoms suggestive of the infection and/or be tested. Topical and systemic corticosteroids and nose washes are contraindicated. The natural course of anosmia seems to be favorable in most cases.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Humans ; Olfaction Disorders/virology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; SARS-CoV-2
    Keywords covid19
    Language French
    Publishing date 2020-06-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2177010-4
    ISSN 1660-9379
    ISSN 1660-9379
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  10. Article ; Online: Oropharyngolaryngeal manifestations in severe toxic epidermal necrolysis: a single-center's retrospective case series.

    Glasson, Nicolas / De Sandre, Cécile / Pantet, Olivier / Reinhard, Antoine / Lambercy, Karma / Sandu, Kishore / Gorostidi, François

    International journal of dermatology

    2023  Volume 62, Issue 11, Page(s) 1384–1390

    Abstract: Background: Toxic epidermal necrolysis is a rare and life-threatening mucocutaneous disease. Although mucosal ear, nose, and throat (ENT) involvement is common, little is known about the characteristics, treatment modalities, and outcomes of these ... ...

    Abstract Background: Toxic epidermal necrolysis is a rare and life-threatening mucocutaneous disease. Although mucosal ear, nose, and throat (ENT) involvement is common, little is known about the characteristics, treatment modalities, and outcomes of these lesions. The aim of this study was to evaluate ENT mucosal lesions in severe toxic epidermal necrolysis patients and analyze their characteristics, treatment modalities, and outcomes, as well as proposing a management algorithm to prevent long-term debilitating sequalae of these lesions.
    Methods: This is a retrospective review of toxic epidermal necrolysis cases treated at the tertiary burns unit of the Lausanne University Hospital CHUV, Switzerland, between 2006 and 2019.
    Results: Out of 19 patients with severe toxic epidermal necrolysis, 17 (89%) underwent a complete ENT examination at admission and 14 (82%) had ENT mucosal involvement. Five (26.3%) patients died during the stay in the intensive care unit. Of the 16 patients who received maximal care, 13 (81%) required orotracheal intubation for a median time of 16 (IQR: 14) days. Out of the 14 patients who survived, four (29%) had long-term ENT complications consisting of synechiaes necessitating subsequent endoscopic procedures. Those four patients all required mechanical ventilation with an orotracheal tube and suffered from hypopharyngeal synechiaes as well as oral and endonasal synechiaes in individual cases.
    Conclusion: This study suggests a high prevalence of ENT synechiaes in patients with severe toxic epidermal necrolysis and requiring orotracheal intubation. Periodic ENT examination could prevent mature synechiae formation in these patients. We propose an algorithm to prevent long-term sequalae in ENT mucosal involvement.
    Language English
    Publishing date 2023-09-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/ijd.16858
    Database MEDical Literature Analysis and Retrieval System OnLINE

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