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  1. Article: Another Look at Compassion Fatigue.

    Carver, Martha L

    Journal of Christian nursing : a quarterly publication of Nurses Christian Fellowship

    2021  Volume 38, Issue 3, Page(s) E25–E27

    Abstract: Abstract: Compassion fatigue has become a more significant concern as nurses have cared for patients during the COVID-19 pandemic. The results of compassion fatigue are detrimental for both nurses and their patients. Both administrative and individual ... ...

    Abstract Abstract: Compassion fatigue has become a more significant concern as nurses have cared for patients during the COVID-19 pandemic. The results of compassion fatigue are detrimental for both nurses and their patients. Both administrative and individual actions can be taken to assess, prevent, and deal with compassion fatigue. Spiritual facets of recognizing the potential for and managing the problem are presented.
    MeSH term(s) Adaptation, Psychological ; Adult ; Burnout, Professional/psychology ; COVID-19/nursing ; COVID-19/psychology ; Compassion Fatigue/psychology ; Empathy ; Humans ; Job Satisfaction ; Nurse-Patient Relations ; Nursing Staff/psychology ; Quality of Life
    Language English
    Publishing date 2021-05-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1057048-2
    ISSN 0743-2550
    ISSN 0743-2550
    DOI 10.1097/CNJ.0000000000000847
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3100: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: A little patience and some grapes.

    Carver, Martha L

    Nursing

    2020  Volume 50, Issue 11, Page(s) 54–55

    MeSH term(s) Aged ; Assisted Living Facilities ; Feeding and Eating Disorders/nursing ; Female ; Hospice and Palliative Care Nursing ; Humans ; Lung Neoplasms/nursing ; Nurse-Patient Relations ; Nursing Staff/psychology ; Vitis
    Language English
    Publishing date 2020-10-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 197895-0
    ISSN 1538-8689 ; 0360-4039
    ISSN (online) 1538-8689
    ISSN 0360-4039
    DOI 10.1097/01.NURSE.0000718912.55991.2d
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1800: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression.

    Chen, Muhan / Pratt, Christopher P / Zeeman, Martha E / Schultz, Nikolaus / Taylor, Barry S / O'Neill, Audrey / Castillo-Martin, Mireia / Nowak, Dawid G / Naguib, Adam / Grace, Danielle M / Murn, Jernej / Navin, Nick / Atwal, Gurinder S / Sander, Chris / Gerald, William L / Cordon-Cardo, Carlos / Newton, Alexandra C / Carver, Brett S / Trotman, Lloyd C

    Cancer cell

    2011  Volume 20, Issue 2, Page(s) 173–186

    Abstract: Hyperactivation of the PI 3-kinase/AKT pathway is a driving force of many cancers. Here we identify the AKT-inactivating phosphatase PHLPP1 as a prostate tumor suppressor. We show that Phlpp1-loss causes neoplasia and, on partial Pten-loss, carcinoma in ... ...

    Abstract Hyperactivation of the PI 3-kinase/AKT pathway is a driving force of many cancers. Here we identify the AKT-inactivating phosphatase PHLPP1 as a prostate tumor suppressor. We show that Phlpp1-loss causes neoplasia and, on partial Pten-loss, carcinoma in mouse prostate. This genetic setting initially triggers a growth suppressive response via p53 and the Phlpp2 ortholog, and reveals spontaneous Trp53 inactivation as a condition for full-blown disease. Surprisingly, the codeletion of PTEN and PHLPP1 in patient samples is highly restricted to metastatic disease and tightly correlated to deletion of TP53 and PHLPP2. These data establish a conceptual framework for progression of PTEN mutant prostate cancer to life-threatening disease.
    MeSH term(s) Disease Progression ; Humans ; Male ; Mutation ; Nuclear Proteins/physiology ; PTEN Phosphohydrolase/genetics ; PTEN Phosphohydrolase/metabolism ; Phosphoprotein Phosphatases/physiology ; Prostatic Neoplasms/metabolism ; Prostatic Neoplasms/pathology
    Chemical Substances Nuclear Proteins ; PHLPP1 protein, human (EC 3.1.3.16) ; Phosphoprotein Phosphatases (EC 3.1.3.16) ; PTEN Phosphohydrolase (EC 3.1.3.67) ; PTEN protein, human (EC 3.1.3.67)
    Language English
    Publishing date 2011-08-05
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2078448-X
    ISSN 1878-3686 ; 1535-6108
    ISSN (online) 1878-3686
    ISSN 1535-6108
    DOI 10.1016/j.ccr.2011.07.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 104: Show issues

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