LIVIVO - Search results -

Search results

Result 1 - 10 of total 21739

Search options

Article ; Online: Frontotemporal dementia presentation in patients with heterozygous p.H157Y variant of

2023 Volume 60, Issue 9, Page(s) 894–904

Abstract: ... of neuroinflammatory processes in neurodegeneration. To date, the p.H157Y variant of : Methods: To determine ... if the p.H157Y variant might be associated with a specific FTD presentation, we compared in each study ...

Abstract	Background: The triggering receptor expressed on myeloid cell 2 (TREM2) is a major regulator of neuroinflammatory processes in neurodegeneration. To date, the p.H157Y variant of Methods: To determine if the p.H157Y variant might be associated with a specific FTD presentation, we compared in each study the cases with age-matched, sex-matched and education-matched groups-a healthy control group (HC) and a group with FTD with neither Results: The two Colombian cases presented with early behavioural changes, greater impairments in general cognition and executive function compared with both HC and Ng-FTD groups. These patients also exhibited brain atrophy in areas characteristic of FTD. Furthermore, TREM2 cases showed increased atrophy compared with Ng-FTD in frontal, temporal, parietal, precuneus, basal ganglia, parahippocampal/hippocampal and cerebellar regions. The Mexican case presented with FTD and motor neuron disease (MND), showing grey matter reduction in basal ganglia and thalamus, and extensive TDP-43 type B pathology. Conclusion: In all TREM2 cases, multiple atrophy peaks overlapped with the maximum peaks of
MeSH term(s)	Humans ; Frontotemporal Dementia/genetics ; Frontotemporal Dementia/pathology ; Alzheimer Disease/genetics ; Alzheimer Disease/pathology ; Brain/diagnostic imaging ; Brain/pathology ; Atrophy ; Membrane Glycoproteins/genetics ; Receptors, Immunologic/genetics
Chemical Substances	TREM2 protein, human ; Membrane Glycoproteins ; Receptors, Immunologic
Language	English
Publishing date	2023-02-22
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	220881-7
ISSN	1468-6244 ; 0022-2593
ISSN (online)	1468-6244
ISSN	0022-2593
DOI	10.1136/jmg-2022-108627
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 177: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Management of pregnancy in autoimmune rheumatic diseases: maternal disease course, gestational and neonatal outcomes and use of medications in the prospectiveItalian P-RHEUM.it study.

Andreoli, Laura / Gerardi, Maria Chiara / Gerosa, Maria / Rozza, Davide / Crisafulli, Francesca / Erra, Roberta / Lini, Daniele / Trespidi, Laura / Padovan, Melissa / Ruffilli, Francesca / Serale, Francesca / Cuomo, Giovanna / Raffeiner, Bernd / Semeraro, Paolo / Tani, Chiara / Chimenti, Maria Sole / Conigliaro, Paola / Hoxha, Ariela / Nalli, Cecilia /

Fredi, Micaela / Lazzaroni, Maria Grazia / Filippini, Matteo / Taglietti, Marco / Franceschini, Franco / Zatti, Sonia / Loardi, Chiara / Orabona, Rossana / Ramazzotto, Francesca / Zanardini, Cristina / Fontana, Giulia / Gozzoli, Giorgia / Barison, Claudia / Bizioli, Paola / Caporali, Roberto Felice / Carrea, Giulia / Ossola, Manuela Wally / Maranini, Beatrice / Silvagni, Ettore / Govoni, Marcello / Morano, Danila / Verteramo, Rosita / Doria, Andrea / Del Ross, Teresa / Favaro, Maria / Calligaro, Antonia / Tonello, Marta / Larosa, Maddalena / Zen, Margherita / Zambon, Alessandra / Mosca, Marta / Zucchi, Dina / Elefante, Elena / Gori, Sabrina / Iannone, Florenzo / Anelli, Maria Grazia / Lavista, Marlea / Abbruzzese, Anna / Fasano, Carlo Giuseppe / D'Angelo, Salvatore / Cutro, Maria Stefania / Picerno, Valentina / Carbone, Teresa / Padula, Angela Anna / Rovere-Querini, Patrizia / Canti, Valentina / De Lorenzo, Rebecca / Cavallo, Ludovica / Ramoni, Véronique / Montecucco, Carlomaurizio / Codullo, Veronica / Milanesi, Alessandra / Pazzola, Giulia / Comitini, Giuseppina / Marvisi, Chiara / Salvarani, Carlo / Epis, Oscar Massimiliano / Benedetti, Sara / Di Raimondo, Giuseppina / Gagliardi, Clizia / Lomater, Claudia / Crepaldi, Gloria / Bellis, Elisa / Bellisai, Francesca / Garcia Gonzalez, Estrella / Pata, Anna Paola / Zerbinati, Martina / Urban, Maria Letizia / Mattioli, Irene / Iuliano, Annamaria / Sebastiani, Giandomenico / Brucato, Antonio Luca / Bizzi, Emanuele / Cutolo, Maurizio / Santo, Leonardo / Tonetta, Sara / Landolfi, Gianpiero / Carrara, Greta / Bortoluzzi, Alessandra / Scirè, Carlo Alberto / Tincani, Angela

RMD open

2024 Volume 10, Issue 2

Abstract: ... in the Italian prospective cohort study P-RHEUM.it.: Methods: Pregnant women with different ARD were enrolled ...

Abstract	Objectives: To investigate pregnancy outcomes in women with autoimmune rheumatic diseases (ARD) in the Italian prospective cohort study P-RHEUM.it. Methods: Pregnant women with different ARD were enrolled for up to 20 gestational weeks in 29 Rheumatology Centres for 5 years (2018-2023). Maternal and infant information were collected in a web-based database. Results: We analysed 866 pregnancies in 851 patients (systemic lupus erythematosus was the most represented disease, 19.6%). Maternal disease flares were observed in 135 (15.6%) pregnancies. 53 (6.1%) pregnancies were induced by assisted reproduction techniques, 61 (7%) ended in miscarriage and 11 (1.3%) underwent elective termination. Obstetrical complications occurred in 261 (30.1%) pregnancies, including 2.3% pre-eclampsia. Two cases of congenital heart block were observed out of 157 pregnancies (1.3%) with anti-Ro/SSA. Regarding treatments, 244 (28.2%) pregnancies were treated with glucocorticoids, 388 (44.8%) with hydroxychloroquine, 85 (9.8%) with conventional synthetic disease-modifying anti-rheumatic drugs and 122 (14.1%) with biological disease-modifying anti-rheumatic drugs. Live births were 794 (91.7%), mostly at term (84.9%); four perinatal deaths (0.5%) occurred. Among 790 newborns, 31 (3.9%) were small-for-gestational-age and 169 (21.4%) had perinatal complications. Exclusive maternal breast feeding was received by 404 (46.7%) neonates. The Edinburgh Postnatal Depression Scale was compiled by 414 women (52.4%); 89 (21.5%) scored positive for emotional distress. Conclusions: Multiple factors including preconception counselling and treat-to-target with pregnancy-compatible medications may have contributed to mitigate disease-related risk factors, yielding limited disease flares, good pregnancy outcomes and frequency of complications which were similar to the Italian general obstetric population. Disease-specific issues need to be further addressed to plan preventative measures.
MeSH term(s)	Humans ; Pregnancy ; Female ; Adult ; Prospective Studies ; Autoimmune Diseases/epidemiology ; Autoimmune Diseases/drug therapy ; Pregnancy Outcome/epidemiology ; Rheumatic Diseases/drug therapy ; Rheumatic Diseases/epidemiology ; Rheumatic Diseases/complications ; Infant, Newborn ; Pregnancy Complications/epidemiology ; Pregnancy Complications/drug therapy ; Antirheumatic Agents/therapeutic use ; Antirheumatic Agents/adverse effects ; Italy/epidemiology ; Glucocorticoids/therapeutic use ; Hydroxychloroquine/therapeutic use ; Hydroxychloroquine/adverse effects
Chemical Substances	Antirheumatic Agents ; Glucocorticoids ; Hydroxychloroquine (4QWG6N8QKH)
Language	English
Publishing date	2024-04-24
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Multicenter Study
ZDB-ID	2812592-7
ISSN	2056-5933 ; 2056-5933
ISSN (online)	2056-5933
ISSN	2056-5933
DOI	10.1136/rmdopen-2024-004091
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Hereditary motor sensory neuropathy with proximal involvement (HMSN-P) associated with TFG p.Pro285Leu variant in an Italian family with a motor neuron disease-like clinical picture.

Cabras, Sara / Di Pede, Francesca / Canosa, Antonio / Grassano, Maurizio / Mongini, Tiziana Enrica / Gadaleta, Giulio / Calvo, Andrea / Chiò, Adriano / Moglia, Cristina / Gallone, Salvatore

Muscle & nerve

2024

Language	English
Publishing date	2024-03-27
Publishing country	United States
Document type	Letter
ZDB-ID	438353-9
ISSN	1097-4598 ; 0148-639X
ISSN (online)	1097-4598
ISSN	0148-639X
DOI	10.1002/mus.28088
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1449: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 551: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Differences Between Plasma and Cerebrospinal Fluid p-tau181 and p-tau231 in Early Alzheimer's Disease.

Pilotto, Andrea / Parigi, Marta / Bonzi, Giulio / Battaglio, Beatrice / Ferrari, Elisabetta / Mensi, Lorenza / Benussi, Alberto / Caratozzolo, Salvatore / Cosseddu, Maura / Turrone, Rosanna / Archetti, Silvana / Ashton, Nicholas J / Zetterberg, Henrik / Giliani, Silvia / Padovani, Alessandro

Journal of Alzheimer's disease : JAD

2022 Volume 87, Issue 3, Page(s) 991–997

Abstract: ... cerebrospinal fluid (CSF) p-tau181 and p-tau231 levels were elevated in the early symptomatic stages of AD. Plasma p ... tau231 and p-tau181 were strongly related to CSF phosphorylated tau, total tau and amyloid and exhibited ... a high accuracy-close to CSF p-tau231 and p-tau181-to identify AD already in the early stage ...

Abstract	Plasma phosphorylated tau species have been recently proposed as peripheral markers of Alzheimer's disease (AD) pathology. In this cross-sectional study including 91 subjects, plasma and cerebrospinal fluid (CSF) p-tau181 and p-tau231 levels were elevated in the early symptomatic stages of AD. Plasma p-tau231 and p-tau181 were strongly related to CSF phosphorylated tau, total tau and amyloid and exhibited a high accuracy-close to CSF p-tau231 and p-tau181-to identify AD already in the early stage of the disease. The findings might support the use as diagnostic and prognostic peripheral AD biomarkers in both research and clinical settings.
MeSH term(s)	Alzheimer Disease/cerebrospinal fluid ; Amyloid beta-Peptides/cerebrospinal fluid ; Biomarkers/cerebrospinal fluid ; Cross-Sectional Studies ; Humans ; Phosphorylation ; tau Proteins/cerebrospinal fluid
Chemical Substances	Amyloid beta-Peptides ; Biomarkers ; tau Proteins
Language	English
Publishing date	2022-04-11
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1440127-7
ISSN	1875-8908 ; 1387-2877
ISSN (online)	1875-8908
ISSN	1387-2877
DOI	10.3233/JAD-215646
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6084: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: MIS-C and co-infection with P. vivax and P. falciparum in a child: a clinical conundrum.

Scalisi, Michela / Giordano, Salvatore / Canduscio, Laura Antonella / Failla, Maria Concetta / Messina, Luca / Sferrazza, Elisa / Rubino, Raffaella / Siracusa, Lucia / Vanella, Veronica / Cascio, Antonio / Colomba, Claudia

Italian journal of pediatrics

2022 Volume 48, Issue 1, Page(s) 130

Abstract: Background: The ongoing Coronavirus Disease 2019 (COVID-19) epidemic represents an unprecedented global health challenge. Many COVID-19 symptoms are similar to symptoms that can occur in other infections. Malaria should always be considered in patients ... ...

Abstract	Background: The ongoing Coronavirus Disease 2019 (COVID-19) epidemic represents an unprecedented global health challenge. Many COVID-19 symptoms are similar to symptoms that can occur in other infections. Malaria should always be considered in patients with SARS-CoV-2 infection returning from endemic areas. Case presentation: We present the first case of multisystem inflammatory syndrome (MIS-C) and Plasmodium vivax-falciparum and SARS-CoV2 coinfection in children. Despite clearance of parassitaemia and a negative COVID-19 nasopharyngeal PCR, the patient's clinical conditions worsened. The World Health Organization (WHO) criteria were used to make the diagnosis of MIS-C. Treatment with intravenous immunoglobulins and methylprednisolone was effective. Conclusions: This case emphasizes the importance of considering malaria diagnosis in patients returning from endemic areas, even in the COVID 19 era. Malaria and SARS-CoV2 co-infection may increase the risk of MIS-C, for which early detection is critical for proper management.
MeSH term(s)	COVID-19/complications ; Child ; Coinfection/diagnosis ; Humans ; Malaria/diagnosis ; Malaria/drug therapy ; Malaria/epidemiology ; Plasmodium falciparum ; RNA, Viral ; SARS-CoV-2 ; Systemic Inflammatory Response Syndrome
Chemical Substances	RNA, Viral
Language	English
Publishing date	2022-07-27
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2088556-8
ISSN	1824-7288 ; 1720-8424
ISSN (online)	1824-7288
ISSN	1720-8424
DOI	10.1186/s13052-022-01311-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1961: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Global cognitive function correlates with P-wave dispersion in frail hypertensive older adults.

Mone, Pasquale / Pansini, Antonella / Calabrò, Francesco / De Gennaro, Stefano / Esposito, Mafalda / Rinaldi, Paolo / Colin, Antonio / Minicucci, Fabio / Coppola, Antonio / Frullone, Salvatore / Santulli, Gaetano

Journal of clinical hypertension (Greenwich, Conn.)

2022 Volume 24, Issue 5, Page(s) 638–643

Abstract: P-Wave Dispersion (PWD) is an ECG parameter defined as the difference between the longest and ... the shortest P-Wave duration. PWD has been associated with hypertension, a leading cause of age-related ...

Abstract	P-Wave Dispersion (PWD) is an ECG parameter defined as the difference between the longest and the shortest P-Wave duration. PWD has been associated with hypertension, a leading cause of age-related cognitive decline. Moreover, hypertension is associated with vascular dementia and Alzheimer's Disease. Based on these considerations, we evaluated PWD and global cognitive function in frail hypertensive older adults with a previous diagnosis of cognitive decline. We evaluated consecutive frail hypertensive patients ≥65-year-old with a Mini-Mental State Examination (MMSE) score <26. Patients with evidence of secondary hypertension, history of stroke, myocardial infarction, or therapy with beta-blockers or acetylcholinesterase inhibitors were excluded. Beta-blocker therapy causes a significant decrease in PWD; patients treated with acetylcholinesterase inhibitors were not included to avoid confounding effects on cognitive function. By examining 180 patients, we found that PWD significantly correlated with MMSE score. Strikingly, these effects were confirmed in a linear multivariate analysis with a regression model. To our knowledge, this is the first study showing that PWD correlates with global cognitive function in frail hypertensive older adults.
MeSH term(s)	Acetylcholinesterase ; Aged ; Cholinesterase Inhibitors ; Cognition ; Cognitive Dysfunction/diagnosis ; Cognitive Dysfunction/etiology ; Frail Elderly ; Humans ; Hypertension/complications ; Hypertension/diagnosis ; Hypertension/drug therapy
Chemical Substances	Cholinesterase Inhibitors ; Acetylcholinesterase (EC 3.1.1.7)
Language	English
Publishing date	2022-03-01
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	2077222-1
ISSN	1751-7176 ; 1524-6175
ISSN (online)	1751-7176
ISSN	1524-6175
DOI	10.1111/jch.14439
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5723: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Radiolabeled Gold Nanoseeds Decorated with Substance P Peptides: Synthesis, Characterization and In Vitro Evaluation in Glioblastoma Cellular Models.

Silva, Francisco / D'Onofrio, Alice / Mendes, Carolina / Pinto, Catarina / Marques, Ana / Campello, Maria Paula Cabral / Oliveira, Maria Cristina / Raposinho, Paula / Belchior, Ana / Di Maria, Salvatore / Marques, Fernanda / Cruz, Carla / Carvalho, Josué / Paulo, António

International journal of molecular sciences

2022 Volume 23, Issue 2

Abstract: ... SP and AuNP-SPTyr8) with a small gold core (ca. 4 nm), carrying DOTA chelators and substance P (SP ...

Abstract	Despite some progress, the overall survival of patients with glioblastoma (GBM) remains extremely poor. In this context, there is a pressing need to develop innovative therapy strategies for GBM, namely those based on nanomedicine approaches. Towards this goal, we have focused on nanoparticles (AuNP-SP and AuNP-SPTyr8) with a small gold core (ca. 4 nm), carrying DOTA chelators and substance P (SP) peptides. These new SP-containing AuNPs were characterized by a variety of analytical techniques, including TEM and DLS measurements and UV-vis and CD spectroscopy, which proved their high in vitro stability and poor tendency to interact with plasma proteins. Their labeling with diagnostic and therapeutic radionuclides was efficiently performed by DOTA complexation with the trivalent radiometals
MeSH term(s)	Cell Line, Tumor ; Endocytosis ; Glioblastoma/drug therapy ; Gold/chemistry ; Humans ; Metal Nanoparticles/chemistry ; Models, Biological ; Peptides/chemical synthesis ; Peptides/chemistry ; Radiopharmaceuticals/chemistry ; Serum Albumin/metabolism ; Spectrophotometry, Ultraviolet ; Substance P/chemical synthesis ; Substance P/chemistry ; Transferrin/metabolism
Chemical Substances	Peptides ; Radiopharmaceuticals ; Serum Albumin ; Transferrin ; Substance P (33507-63-0) ; Gold (7440-57-5)
Language	English
Publishing date	2022-01-06
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms23020617
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: A patient with demyelinating CMT carrying the p.Y347C heterozygous variant of the MME gene and the p.L131F heterozygous variant of the HARS1 gene.

Parisi, Mattia / Canosa, Antonio / Tessa, Alessandra / Ferrero, Bruno / Gallone, Salvatore

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

2022 Volume 44, Issue 4, Page(s) 1455–1456

MeSH term(s)	Humans ; Charcot-Marie-Tooth Disease/genetics ; Mutation/genetics ; Heterozygote
Chemical Substances	MME (78185-58-7)
Language	English
Publishing date	2022-12-15
Publishing country	Italy
Document type	Letter
ZDB-ID	2016546-8
ISSN	1590-3478 ; 1590-1874
ISSN (online)	1590-3478
ISSN	1590-1874
DOI	10.1007/s10072-022-06553-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1877: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: P-SILI in critically ill COVID-19 patients: Macklin effect and the choice of noninvasive ventilatory support type.

Belletti, Alessandro / Vetrugno, Luigi / Deana, Cristian / Palumbo, Diego / Maggiore, Salvatore M / Landoni, Giovanni

Critical care (London, England)

2023 Volume 27, Issue 1, Page(s) 38

MeSH term(s)	Humans ; COVID-19 ; Critical Illness/therapy ; Mediastinal Emphysema ; Respiration, Artificial
Language	English
Publishing date	2023-01-24
Publishing country	England
Document type	Letter ; Comment
ZDB-ID	2041406-7
ISSN	1466-609X ; 1364-8535
ISSN (online)	1466-609X
ISSN	1364-8535
DOI	10.1186/s13054-023-04313-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5517: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Pru p 3 sensitization in children with allergy to Parietaria pollens.

Ciprandi, Giorgio / Del Barba, Paolo / Silvestri, Michela / Barberi, Salvatore / Tosca, Maria Angela

Acta bio-medica : Atenei Parmensis

2019 Volume 90, Issue 2, Page(s) 265–268

Abstract: Background: Pru p 3 is the major allergen of the peach and belongs to the LTP family. Pru p 3 ... However, a previous experience partially downsized the potential danger of Pru p 3 sensitization in a group of adult ... rhinitics. This study aimed to evaluate the real impact of Pru p 3 sensitization in children in a real-world ...

Abstract	Background: Pru p 3 is the major allergen of the peach and belongs to the LTP family. Pru p 3 sensitization has been associated with severe allergic symptoms after eating LTP-containing foods. However, a previous experience partially downsized the potential danger of Pru p 3 sensitization in a group of adult rhinitics. This study aimed to evaluate the real impact of Pru p 3 sensitization in children in a real-world setting. Methods: 82 consecutive paediatric patients (55 males and 27 females, mean age 8.19±4.23 years) with allergic rhinitis due to Parietaria pollen allergy and sensitization to Pru p 3, documented by ISAC test, were evaluated. Serum IgE was measured by ImmunoCap method. Allergic symptoms occurring after ingesting LTP-containing foods were considered and scored as oral allergy syndrome, food allergy, and anaphylaxis. Results: About one-quarter of Pru p 3-sensitized children reported anaphylaxis after ingesting LTP-containing foods, about half reported food allergy or oral allergy syndrome. Only ¼ was merely sensitized. Conclusions: Pru p 3 sensitization deserves careful attention in children contrary to what might occur in adult patients. It could depend on the age and the serum IgE level. Thus, Pru p 3 sensitization should be adequately interepreted and managed in clinical practice.
MeSH term(s)	Age Factors ; Anaphylaxis/etiology ; Child ; Child, Preschool ; Cohort Studies ; Female ; Food Hypersensitivity/immunology ; Food Hypersensitivity/physiopathology ; Humans ; Immunization/adverse effects ; Italy ; Male ; Parietaria/immunology ; Patient Safety ; Retrospective Studies ; Rhinitis, Allergic/immunology ; Rhinitis, Allergic/physiopathology ; Rhinitis, Allergic, Seasonal/immunology ; Rhinitis, Allergic, Seasonal/prevention & control ; Risk Assessment
Language	English
Publishing date	2019-05-23
Publishing country	Italy
Document type	Journal Article
ZDB-ID	2114240-3
ISSN	2531-6745 ; 0392-4203
ISSN (online)	2531-6745
ISSN	0392-4203
DOI	10.23750/abm.v90i2.7611
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 925: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito