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  1. Article ; Online: Spherical Aromaticity of Inorganic Cage Molecules This work was supported by the Alexander von Humboldt Stiftung (Z. Chen), the Centre National de la Recherche Scientifique (H. Jiao), and the Fonds der Chemischen Industrie. We thank Prof. Dr. T. F. Fässler for his helpful discussion and reprints.

    Hirsch, Andreas / Chen, Zhongfang / Jiao, Haijun

    Angewandte Chemie (International ed. in English)

    2001  Volume 40, Issue 15, Page(s) 2834–2838

    Language English
    Publishing date 2001-08-03
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
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  2. Article ; Online: Disability, Caregiving, and the Search for Equity in Transplant.

    Chen, Melissa E / Toledo, Alexander H

    JAMA surgery

    2023  Volume 158, Issue 4, Page(s) 392–393

    MeSH term(s) Humans ; Healthcare Disparities ; Transplantation ; Disabled Persons
    Language English
    Publishing date 2023-02-15
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2701841-6
    ISSN 2168-6262 ; 2168-6254
    ISSN (online) 2168-6262
    ISSN 2168-6254
    DOI 10.1001/jamasurg.2022.7759
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Professional Guidelines for the Care of Extremely Premature Neonates: Clinical Reasoning versus Ethical Theory.

    Chen, H Alexander / Drago, Matthew J

    The Journal of clinical ethics

    2023  Volume 34, Issue 3, Page(s) 233–244

    Abstract: AbstractProfessional statements guide neonatal resuscitation thresholds at the border of viability. A 2015 systematic review of international guidelines by Guillen et al. found considerable variability between statements' clinical recommendations for ... ...

    Abstract AbstractProfessional statements guide neonatal resuscitation thresholds at the border of viability. A 2015 systematic review of international guidelines by Guillen et al. found considerable variability between statements' clinical recommendations for infants at 23-24 weeks gestational age (GA). The authors concluded that differences in the type of data included were one potential source for differing resuscitation thresholds within this "ethical gray zone." How statements present ethical considerations that support their recommendations, and how this may account for variability, has not been as rigorously explored. We performed a mixed-methods exploratory analysis of 25 current international guidelines for neonatal resuscitation at 22+0-25+0 weeks GA. Qualitative analysis using a modified grounded theory yielded 34 distinct codes, eight categories, and four overarching themes. Three themes, consequentialism, principlism, and rights-based, consisted of concepts central to these ethical frameworks. The fourth theme, clinical reasoning, described counseling practices, medical management, outcomes data, and prognostic uncertainty, without any ethical context. The theme of clinical reasoning appeared in 22 of 25 guidelines. Ten guidelines lacked any ethical theme. Guidelines with an identified ethical theme were more likely to recommend comfort care than guidelines without an identified ethical theme, and recommended it at a higher average GA (22.7 weeks vs. 22.0 weeks,
    MeSH term(s) Humans ; Infant, Newborn ; Clinical Reasoning ; Ethical Theory ; Gestational Age ; Resuscitation ; Resuscitation Orders ; Uncertainty ; Practice Guidelines as Topic
    Language English
    Publishing date 2023-10-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1122655-9
    ISSN 1046-7890
    ISSN 1046-7890
    DOI 10.1086/726813
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    Zs.A 3456: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  4. Article ; Online: Response Regarding: Robotic Cholecystectomies: What Are They Good for? A Retrospective Study of Robotic Versus Conventional Cases.

    Chen, H Alexander / Corey, Britney

    The Journal of surgical research

    2022  Volume 281, Page(s) 337

    MeSH term(s) Retrospective Studies ; Robotic Surgical Procedures ; Cholecystectomy/adverse effects ; Robotics ; Laparoscopy ; Treatment Outcome
    Language English
    Publishing date 2022-09-28
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80170-7
    ISSN 1095-8673 ; 0022-4804
    ISSN (online) 1095-8673
    ISSN 0022-4804
    DOI 10.1016/j.jss.2022.09.001
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  5. Article ; Online: A comparison of licensed driver counts from the Federal Highway Administration and driver licensing agencies in 11 states.

    Evans, Alexander / Benedetti, Marco H / Chang, Gregory / Shoots-Reinhard, Brittany / Chen, Zhenhua / Smith, Gary A / Zhu, Motao

    Traffic injury prevention

    2024  Volume 25, Issue 2, Page(s) 133–137

    Abstract: ... ...

    Abstract Objective
    MeSH term(s) Humans ; Accidents, Traffic ; Automobile Driving ; Licensure ; Databases, Factual ; Government Agencies
    Language English
    Publishing date 2024-01-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2089818-6
    ISSN 1538-957X ; 1538-9588
    ISSN (online) 1538-957X
    ISSN 1538-9588
    DOI 10.1080/15389588.2023.2278412
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  6. Article ; Online: Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry: A Strategy for Optimization, Characterization, and Quantification of Antioxidant Nitro Derivatives.

    Chen, Kitmin / Edgar, Alexander S / Wong, Camille H / Yang, Dali

    ACS omega

    2022  Volume 7, Issue 36, Page(s) 32701–32707

    Abstract: As an antioxidant, ...

    Abstract As an antioxidant,
    Language English
    Publishing date 2022-09-06
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.2c04376
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  7. Article ; Online: Sniffing out meaning: Chemosensory and semantic neural network changes in sommeliers.

    Carreiras, Manuel / Quiñones, Ileana / Chen, H Alexander / Vázquez-Araujo, Laura / Small, Dana / Frost, Ram

    Human brain mapping

    2024  Volume 45, Issue 2, Page(s) e26564

    Abstract: Wine tasting is a very complex process that integrates a combination of sensation, language, and memory. Taste and smell provide perceptual information that, together with the semantic narrative that converts flavor into words, seem to be processed ... ...

    Abstract Wine tasting is a very complex process that integrates a combination of sensation, language, and memory. Taste and smell provide perceptual information that, together with the semantic narrative that converts flavor into words, seem to be processed differently between sommeliers and naïve wine consumers. We investigate whether sommeliers' wine experience shapes only chemosensory processing, as has been previously demonstrated, or if it also modulates the way in which the taste and olfactory circuits interact with the semantic network. Combining diffusion-weighted images and fMRI (activation and connectivity) we investigated whether brain response to tasting wine differs between sommeliers and nonexperts (1) in the sensory neural circuits representing flavor and/or (2) in the neural circuits for language and memory. We demonstrate that training in wine tasting shapes the microstructure of the left and right superior longitudinal fasciculus. Using mediation analysis, we showed that the experience modulates the relationship between fractional anisotropy and behavior: the higher the fractional anisotropy the higher the capacity to recognize wine complexity. In addition, we found functional differences between sommeliers and naïve consumers affecting the flavor sensory circuit, but also regions involved in semantic operations. The former reflects a capacity for differential sensory processing, while the latter reflects sommeliers' ability to attend to relevant sensory inputs and translate them into complex verbal descriptions. The enhanced synchronization between these apparently independent circuits suggests that sommeliers integrated these descriptions with previous semantic knowledge to optimize their capacity to distinguish between subtle differences in the qualitative character of the wine.
    MeSH term(s) Humans ; Semantics ; Semantic Web ; Smell/physiology ; Taste Perception ; Sensation ; Taste/physiology
    Language English
    Publishing date 2024-01-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1197207-5
    ISSN 1097-0193 ; 1065-9471
    ISSN (online) 1097-0193
    ISSN 1065-9471
    DOI 10.1002/hbm.26564
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    Zs.A 4028: Show issues Location:
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  8. Article ; Online: Medical and surgical retreatment for uterine leiomyoma after myomectomy.

    Li, Alicia H / Chen, Ling / Melamed, Alexander / Hershman, Dawn L / Wright, Jason D

    BJOG : an international journal of obstetrics and gynaecology

    2023  Volume 130, Issue 7, Page(s) 835–837

    MeSH term(s) Female ; Humans ; Uterine Myomectomy ; Leiomyoma/surgery ; Uterine Neoplasms/surgery ; Retreatment ; Hysterectomy ; Uterine Artery Embolization
    Language English
    Publishing date 2023-02-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2000931-8
    ISSN 1471-0528 ; 0306-5456 ; 1470-0328
    ISSN (online) 1471-0528
    ISSN 0306-5456 ; 1470-0328
    DOI 10.1111/1471-0528.17409
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  9. Article ; Online: Optimizing the Pd Sites in Pure Metallic Aerogels for Efficient Electrocatalytic H

    Zhang, Xin / Wang, Cui / Chen, Kai / Clark, Adam H / Hübner, René / Zhan, Jinhua / Zhang, Liang / Eychmüller, Alexander / Cai, Bin

    Advanced materials (Deerfield Beach, Fla.)

    2023  Volume 35, Issue 14, Page(s) e2211512

    Abstract: Decentralized electrochemical production of hydrogen peroxide (H ...

    Abstract Decentralized electrochemical production of hydrogen peroxide (H
    Language English
    Publishing date 2023-03-02
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1474949-X
    ISSN 1521-4095 ; 0935-9648
    ISSN (online) 1521-4095
    ISSN 0935-9648
    DOI 10.1002/adma.202211512
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  10. Article: So, you want to be a doctor? Try blind tasting

    Chen, H. Alexander

    Journal of wine research. 2020 July 2, v. 31, no. 3

    2020  

    Abstract: Blind wine tasting and differential diagnoses of human illness rely on both sensory examination and an existing knowledge base in order to deduce a specific wine varietal and human disease, respectively. Although knowledge is not directly transferable ... ...

    Abstract Blind wine tasting and differential diagnoses of human illness rely on both sensory examination and an existing knowledge base in order to deduce a specific wine varietal and human disease, respectively. Although knowledge is not directly transferable across these disciplines, they utilize similar deductive and perceptual processes. In order to identify an unknown wine, one must recognize the visual, aromatic, and textural components of the wine, as well as draw upon one’s knowledge of which varietals, vintages, and locations correspond to one’s perception. Similarly, patients may present with non-specific symptoms (e.g. cough, fever, headache, etc.), and physicians often do not know the diagnosis before entering the exam room. It is a doctor’s job to draw upon a knowledge of disease presentation and to interact with the patient to deduce the cause of their symptoms. In a clinical exam, physicians rely on their senses of touch, hearing, and sight to narrow down the possible list of diseases. For pre-medical and medical students, blind wine tastings are a chance to practice deduction and develop an approach to clinical reasoning.
    Keywords cough ; fever ; headache ; human diseases ; patients ; research ; wines
    Language English
    Dates of publication 2020-0702
    Size p. 240-246.
    Publishing place Routledge
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 2021770-5
    ISSN 1469-9672 ; 0957-1264
    ISSN (online) 1469-9672
    ISSN 0957-1264
    DOI 10.1080/09571264.2020.1796610
    Database NAL-Catalogue (AGRICOLA)

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