LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 23

Search options

  1. Article: Medicinal plants used by rural Thai people to treat non-communicable diseases and related symptoms.

    Nguanchoo, Varangrat / Balslev, Henrik / Sadgrove, Nicholas J / Phumthum, Methee

    Heliyon

    2023  Volume 9, Issue 1, Page(s) e12758

    Abstract: Non-communicable diseases (NCDs) are becoming more common in remote regions, whereas previously they were more common in middle-class to wealthy societies. The rising prevalence and severity of NCDs has increased the demand for medical innovation in this ...

    Abstract Non-communicable diseases (NCDs) are becoming more common in remote regions, whereas previously they were more common in middle-class to wealthy societies. The rising prevalence and severity of NCDs has increased the demand for medical innovation in this space. In this regard, knowledge of traditional medicines used in the treatment of NCDs, by people in the remote communities of Thailand, represents an innovation opportunity. This study aims to use data on ethnomedicinal plants used by local Thai people to identify plant candidates for study of safety and efficacy against a range of specified NCDs. Data were taken from both the literature and interviews from 230 locations in Thailand. The consulted literature was published in the years from 1990 to 2020. Ethnomedicinal field observations were made in person, in villages in Nan and Chiang Rai provinces, in 2021. Data includes names of plants used to target NCDs, and names of target diseases. Important plant species were identified based on the number of use reports and use values together with results from Bayesian approach. A total of 766 plant species were recorded in the treatment of NCDs. Most of the species that were described by informants were used to target diabetes, hypertension, chronic respiratory and renal diseases. This study proposes several plant species that have potential as treatments against NCDs. Many of these important species have insufficient scientific data to support their uses. The study suggests that assessment of efficacy and safety should be the next logical steps.
    Language English
    Publishing date 2023-01-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2022.e12758
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article: Medicinal Plants Used for Treating Mild Covid-19 Symptoms Among Thai Karen and Hmong.

    Phumthum, Methee / Nguanchoo, Varangrat / Balslev, Henrik

    Frontiers in pharmacology

    2021  Volume 12, Page(s) 699897

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2021-07-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2021.699897
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Fundamental Chemistry of Essential Oils and Volatile Organic Compounds, Methods of Analysis and Authentication.

    Sadgrove, Nicholas J / Padilla-González, Guillermo F / Phumthum, Methee

    Plants (Basel, Switzerland)

    2022  Volume 11, Issue 6

    Abstract: The current text provides a comprehensive introduction to essential oils, their biosynthesis, naming, analysis, and chemistry. Importantly, this text quickly brings the reader up to a level of competence in the authentication of essential oils and their ... ...

    Abstract The current text provides a comprehensive introduction to essential oils, their biosynthesis, naming, analysis, and chemistry. Importantly, this text quickly brings the reader up to a level of competence in the authentication of essential oils and their components. It gives detailed descriptions of enantiomers and other forms of stereoisomers relevant to the study of natural volatiles and essential oils. The text also describes GC-MS work and provides tips on rapid calculation of arithmetic indices, how to interpret suggested names from the NIST mass spectral library, and what additional efforts are required to validate essential oils and defeat sophisticated adulteration tactics. In brief, essential oils are mixtures of volatile organic compounds that were driven out of the raw plant material in distillation, condensed into an oil that is strongly aroma emitting, and collected in a vessel as the top layer (uncommonly bottom layer) of two phase separated liquids: oil and water. Essential oils commonly include components derived from two biosynthetic groups, being terpenes (monoterpenes, sesquiterpenes and their derivatives) and phenylpropanoids (aromatic ring with a propene tail). The current text provides details of how terpenes and phenylpropanoids are further categorised according to their parent skeleton, then recognised by the character of oxidation, which may be from oxygen, nitrogen, or sulphur, or the presence/absence of a double bond. The essential oil's science niche is an epicentre of individuals from diverse backgrounds, such as aromatherapy, pharmacy, synthetic and analytical chemistry, or the hobbyist. To make the science more accessible to the curious student or researcher, it was necessary to write this fundamentals-level introduction to the chemistry of essential oils (i.e., organic chemistry in the context of essential oils), which is herein presented as a comprehensive and accessible overview. Lastly, the current review constitutes the only resource that highlights common errors and explains in simplistic detail how to correctly interpret GC-MS data then accurately present the respective chemical information to the wider scientific audience. Therefore, detailed study of the contents herein will equip the individual with prerequisite knowledge necessary to effectively analyse an essential oil and make qualified judgement on its authenticity.
    Language English
    Publishing date 2022-03-16
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants11060789
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Anti-Infectious Plants of The Thai Karen: A Meta-Analysis.

    Phumthum, Methee / Balslev, Henrik

    Antibiotics (Basel, Switzerland)

    2020  Volume 9, Issue 6

    Abstract: Pharmacology has developed many drugs to treat infections, but many people, especially in developing countries, cannot afford to purchase them, and still depend on traditional knowledge and local medicinal plants to fight off infections. In addition, ... ...

    Abstract Pharmacology has developed many drugs to treat infections, but many people, especially in developing countries, cannot afford to purchase them, and still depend on traditional knowledge and local medicinal plants to fight off infections. In addition, numerous microbes have developed resistance to the pharmaceutical drugs developed to fight them, and for many, such as Covid-19, effective drugs remain to be found. Ethnomedicinal knowledge is useful, not only for local people as a source of medicine for primary health care, but also for new pharmacological discoveries. This study aimed to identify the plants that the Karen, the largest hill-tribe ethnic minority in northern and western Thailand, use for treatments of infectious diseases. We present a meta-analysis of data from 16 ethnobotanical studies of 25 Karen villages with the aim of understanding traditional knowledge and treatments and point to potential plants for further pharmacological development. The Karen used 127 plant species from 59 plant families to treat infections and infectious diseases. The Cultural Important Index (CI) showed that the Leguminosae, Euphorbiaceae, Asteraceae, Lauraceae, Apocynaceae, Menispermaceae, and Lamiaceae were the most commonly used families. As for species,
    Keywords covid19
    Language English
    Publishing date 2020-06-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics9060298
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Medicinal plants used by rural Thai people to treat non-communicable diseases and related symptoms

    Varangrat Nguanchoo / Henrik Balslev / Nicholas J. Sadgrove / Methee Phumthum

    Heliyon, Vol 9, Iss 1, Pp e12758- (2023)

    2023  

    Abstract: Non-communicable diseases (NCDs) are becoming more common in remote regions, whereas previously they were more common in middle-class to wealthy societies. The rising prevalence and severity of NCDs has increased the demand for medical innovation in this ...

    Abstract Non-communicable diseases (NCDs) are becoming more common in remote regions, whereas previously they were more common in middle-class to wealthy societies. The rising prevalence and severity of NCDs has increased the demand for medical innovation in this space. In this regard, knowledge of traditional medicines used in the treatment of NCDs, by people in the remote communities of Thailand, represents an innovation opportunity.This study aims to use data on ethnomedicinal plants used by local Thai people to identify plant candidates for study of safety and efficacy against a range of specified NCDs.Data were taken from both the literature and interviews from 230 locations in Thailand. The consulted literature was published in the years from 1990 to 2020. Ethnomedicinal field observations were made in person, in villages in Nan and Chiang Rai provinces, in 2021. Data includes names of plants used to target NCDs, and names of target diseases. Important plant species were identified based on the number of use reports and use values together with results from Bayesian approach. A total of 766 plant species were recorded in the treatment of NCDs. Most of the species that were described by informants were used to target diabetes, hypertension, chronic respiratory and renal diseases. This study proposes several plant species that have potential as treatments against NCDs. Many of these important species have insufficient scientific data to support their uses. The study suggests that assessment of efficacy and safety should be the next logical steps.
    Keywords Ethnobotany ; Medicinal plant ; Hypertension ; Diabetes ; Chronic respiratory diseases ; NCDs ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Subject code 580
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article: High-Value Plant Species Used for the Treatment of "Fever" by the Karen Hill Tribe People.

    Phumthum, Methee / Sadgrove, Nicholas J

    Antibiotics (Basel, Switzerland)

    2020  Volume 9, Issue 5

    Abstract: The symptom "fever" is generally not itself a terminal condition. However, it does occur with common mild to severe ailments afflicting the world population. Several allopathic medicines are available to attenuate fever by targeting the pathogen or the ... ...

    Abstract The symptom "fever" is generally not itself a terminal condition. However, it does occur with common mild to severe ailments afflicting the world population. Several allopathic medicines are available to attenuate fever by targeting the pathogen or the symptom itself. However, many people in marginal civilizations are obligated to use locally grown medicinal plants due to limited access to common pharmaceuticals. The Karen ethnic group is the biggest ethnic minority group in the hill-tribes of Thailand. They utilise a vast repertoire of medicinal plant species. Since many modern drugs were discovered out of traditional therapies, it is possible to discover new allopathic drugs in the treatment of fever and associated pathogens from the Karen people. Thus, this study aims to identify and record the ethnomedicinal plants they used for the treatment of "fever". The names of plants used by the Thai Karen people for the treatment of fever were mined from publications on ethnomedicinal uses. Useful plant species and families were identified using the Cultural Importance Index (CI). With the mined data, 125 plant species from 52 families were identified, distributed across 25 Karen villages. A chemical cross-examination of these species provided valuable insights into chemical classes worthy of further investigation in the context of fever and associated pathogens.
    Keywords covid19
    Language English
    Publishing date 2020-04-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics9050220
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article: Using ICPC-2 Standard to Identify Thai Zingiberaceae of Pharmacological Interest.

    Phumthum, Methee / Balslev, Henrik

    Plants (Basel, Switzerland)

    2020  Volume 9, Issue 7

    Abstract: The Economic Botany Data Collection Standard (EBDCS) is a widely used standard among ethnobotanists. However, this standard classifies ethnomedicinal uses into categories based on local peoples' perception. It is difficult to apply in pharmacological ... ...

    Abstract The Economic Botany Data Collection Standard (EBDCS) is a widely used standard among ethnobotanists. However, this standard classifies ethnomedicinal uses into categories based on local peoples' perception. It is difficult to apply in pharmacological research. The International Classification of Primary Care (ICPC), now updated to ICPC-2, is more related to medical terms, but is rarely used among ethnobotanists. This study aims to apply the ICPC-2 to classify metadata of the ethnomedicinal uses of Zingiberaceae plants in Thailand, in order to identify important medicinal taxa for future research. Data on the ethnomedicinal uses of Thai gingers were collected from 62 theses, journal articles, scientific reports and a book, published between 1990 and 2019. Scientific plant names were updated using The World Checklist of Vascular Plants (WCVP) website. Informant Consensus Factor (ICF) was used to identify the medicinal issues commonly treated with gingers, and the Cultural Importance Index (CI) was used to identify species that might have pharmacological potential. We found records of 76 ginger species with ethnomedicinal uses, and together they had 771 use reports. The gingers were commonly used for treatments related to digestive system conditions, particularly abdominal pain and flatulence. Gingers remain exceedingly important in Thai ethnomedicine, with a high number of useful species. They are used to treat a variety of health conditions, but most commonly such ones that are related to the digestive system. Apart from the popular studied ginger,
    Language English
    Publishing date 2020-07-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants9070906
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Book ; Online: Anti-Infectious Plants of The Thai Karen

    Methee Phumthum / Henrik Balslev

    Antibiotics ; Volume 9 ; Issue 6

    A Meta-Analysis

    2020  

    Abstract: Pharmacology has developed many drugs to treat infections, but many people, especially in developing countries, cannot afford to purchase them, and still depend on traditional knowledge and local medicinal plants to fight off infections. In addition, ... ...

    Abstract Pharmacology has developed many drugs to treat infections, but many people, especially in developing countries, cannot afford to purchase them, and still depend on traditional knowledge and local medicinal plants to fight off infections. In addition, numerous microbes have developed resistance to the pharmaceutical drugs developed to fight them, and for many, such as Covid-19, effective drugs remain to be found. Ethnomedicinal knowledge is useful, not only for local people as a source of medicine for primary health care, but also for new pharmacological discoveries. This study aimed to identify the plants that the Karen, the largest hill-tribe ethnic minority in northern and western Thailand, use for treatments of infectious diseases. We present a meta-analysis of data from 16 ethnobotanical studies of 25 Karen villages with the aim of understanding traditional knowledge and treatments and point to potential plants for further pharmacological development. The Karen used 127 plant species from 59 plant families to treat infections and infectious diseases. The Cultural Important Index (CI) showed that the Leguminosae, Euphorbiaceae, Asteraceae, Lauraceae, Apocynaceae, Menispermaceae, and Lamiaceae were the most commonly used families. As for species, Cleidion javanicum, Tinospora crispa, Litsea cubeba, Aesculus assamica, Tadehagi triquetrum, Senna alata, Tithonia diversifolia, Embelia sessiliflora, and Combretum indicum were the most commonly used in treatments of infectious diseases. We suggest that these plant species should be the first to be pharmacologically tested for possible development of medicines, and the remaining species registered should subsequently undergo testing.
    Keywords ethnobotany ; ethnomedicinal plants ; infectious diseases ; antimicrobial ; bacterial ; fungal ; viral ; Tinospora crispa ; Cleidion javanicum ; Litsea cubeba ; covid19
    Subject code 580
    Language English
    Publishing date 2020-06-02
    Publisher Multidisciplinary Digital Publishing Institute
    Publishing country ch
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: Anti-Infectious Plants of The Thai Karen

    Methee Phumthum / Henrik Balslev

    Antibiotics, Vol 9, Iss 298, p

    A Meta-Analysis

    2020  Volume 298

    Abstract: Pharmacology has developed many drugs to treat infections, but many people, especially in developing countries, cannot afford to purchase them, and still depend on traditional knowledge and local medicinal plants to fight off infections. In addition, ... ...

    Abstract Pharmacology has developed many drugs to treat infections, but many people, especially in developing countries, cannot afford to purchase them, and still depend on traditional knowledge and local medicinal plants to fight off infections. In addition, numerous microbes have developed resistance to the pharmaceutical drugs developed to fight them, and for many, such as Covid-19, effective drugs remain to be found. Ethnomedicinal knowledge is useful, not only for local people as a source of medicine for primary health care, but also for new pharmacological discoveries. This study aimed to identify the plants that the Karen, the largest hill-tribe ethnic minority in northern and western Thailand, use for treatments of infectious diseases. We present a meta-analysis of data from 16 ethnobotanical studies of 25 Karen villages with the aim of understanding traditional knowledge and treatments and point to potential plants for further pharmacological development. The Karen used 127 plant species from 59 plant families to treat infections and infectious diseases. The Cultural Important Index (CI) showed that the Leguminosae, Euphorbiaceae, Asteraceae, Lauraceae, Apocynaceae, Menispermaceae, and Lamiaceae were the most commonly used families. As for species, Cleidion javanicum , Tinospora crispa , Litsea cubeba , Aesculus assamica , Tadehagi triquetrum , Senna alata , Tithonia diversifolia , Embelia sessiliflora , and Combretum indicum were the most commonly used in treatments of infectious diseases. We suggest that these plant species should be the first to be pharmacologically tested for possible development of medicines, and the remaining species registered should subsequently undergo testing.
    Keywords ethnobotany ; ethnomedicinal plants ; infectious diseases ; antimicrobial ; bacterial ; fungal ; Therapeutics. Pharmacology ; RM1-950 ; covid19
    Subject code 580
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Article: Comparative Metabolomics of Reproductive Organs in the Genus

    Green, Alison / Padilla-Gonzalez, Guillermo Federico / Phumthum, Methee / Simmonds, Monique S J / Sadgrove, Nicholas J

    Plants (Basel, Switzerland)

    2021  Volume 10, Issue 12

    Abstract: ... Fruit ... ...

    Abstract Fruit from
    Language English
    Publishing date 2021-12-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants10122695
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top