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  1. Article: Effect and mechanisms of Gambi-jung against high-fat diet-induced cardiac apoptosis in mice.

    Park, Yea-Jin / Kim, Hyo-Jung / Koh, Duck-Jae / Kim, Eunjoo / Lim, Young-Woo / An, Hyo-Jin

    Heliyon

    2024  Volume 10, Issue 8, Page(s) e29161

    Abstract: Obesity is associated with an increased risk of cardiovascular disease. Gambi-jung (GBJ ...

    Abstract Obesity is associated with an increased risk of cardiovascular disease. Gambi-jung (GBJ), a modified herbal formula of Taeumjowi-tang, induces weight loss in high-fat diet (HFD)-fed obese mice. Meanwhile, concerns have been raised regarding
    Language English
    Publishing date 2024-04-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e29161
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Therapeutic effects of Gambi-jung for the treatment of obesity.

    Park, Yea-Jin / Cominguez, Divina C / Kim, Hyo-Jung / Jin, Jong-Sik / Koh, Duck-Jae / Kim, Seo-Young / Lim, Young-Woo / Park, Young-Bae / An, Hyo-Jin

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    2021  Volume 141, Page(s) 111838

    Abstract: ... and central nervous system (CVS). Gambi-jung (GBJ) is a modified prescription of Taeumjowi-tang (TJT ...

    Abstract Obesity is known as metabolic syndrome and it affects many tissues including adipose tissue, liver, and central nervous system (CVS). Gambi-jung (GBJ) is a modified prescription of Taeumjowi-tang (TJT), which has been used to treat obesity in Korea. GBJ is composed of 90% Ephedra sinica Stapf (ES). Therefore, the present study was designed to assess the antiobesity effects of GBJ and to compare the effects of GBJ and ES on obesity. GBJ administration remarkably reduced the body weight, Body mass index (BMI), and body fat percentage compared to the ES administration in human subjects. GBJ-treated mice had lower white adipose tissue (WAT) amounts than ES-treated mice. GBJ and ES administration enhanced adenosine monophosphate-activated protein kinase (AMPK) expression in 3T3-L1 adipocytes, epididymal WAT and liver of HFD-induced obese mice. Moreover, GBJ and ES reduced food intake by suppressing the mRNA levels of orexigenic peptides, agouti-related protein (AgRP) and neuropeptide-Y (NPY), as well as AMPK in the brain of HFD-induced obese mice. Furthermore, GBJ-treated mice had dramatically lower expression of macrophage marker F4/80 in epididymal WAT than those of ES-treated mice. Based on these results, we suggest the use of GBJ as a natural drug to control weight gain.
    MeSH term(s) 3T3-L1 Cells ; Adipose Tissue, White/drug effects ; Adult ; Aged ; Animals ; Anti-Obesity Agents/therapeutic use ; Appetite Depressants/chemistry ; Appetite Depressants/pharmacology ; Body Composition/drug effects ; Body Mass Index ; Eating/drug effects ; Ephedra sinica/chemistry ; Ephedrine/chemistry ; Ephedrine/pharmacology ; Female ; Humans ; MAP Kinase Signaling System ; Male ; Mice ; Mice, Inbred C57BL ; Middle Aged ; Obesity/drug therapy ; Plant Extracts/therapeutic use ; Weight Loss/drug effects
    Chemical Substances Anti-Obesity Agents ; Appetite Depressants ; Plant Extracts ; gambi-jung ; Ephedrine (GN83C131XS)
    Language English
    Publishing date 2021-06-25
    Publishing country France
    Document type Journal Article
    ZDB-ID 392415-4
    ISSN 1950-6007 ; 0753-3322 ; 0300-0893
    ISSN (online) 1950-6007
    ISSN 0753-3322 ; 0300-0893
    DOI 10.1016/j.biopha.2021.111838
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    In stock of ZB MED Cologne/Königswinter

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  3. Article: In Memoriam: Suk Jung Choo (1964-2023).

    Kim, Ho Jin / Kim, Hong Rae / Park, Sung Jun / Kim, Joon Bum

    Journal of chest surgery

    2023  Volume 56, Issue 6, Page(s) 371–373

    Language English
    Publishing date 2023-11-01
    Publishing country Korea (South)
    Document type Editorial
    ISSN 2765-1606
    ISSN 2765-1606
    DOI 10.5090/jcs.23.148
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  4. Article: Feasibility of combination of Gun-Chil-Jung and cytokine-induced killer cells-based immunotherapy for terminal hepatocellular carcinoma patient: a case report.

    Park, Chan-Ran / Bae, Hye-Ri / Lee, Ga-Young / Son, Chang-Gue / Cho, Jung-Hyo / Cho, Chong-Kwan / Lee, Nam-Hun

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1203379

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2023-08-30
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1203379
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  5. Article ; Online: The Survival Benefit of Combination Therapy With Mild Temperature Hyperthermia and an Herbal Prescription of Gun-Chil-Jung in 54 Cancer Patients Treated With Chemotherapy or Radiation Therapy: A Retrospective Study.

    Jun, Hyeong Joon / Park, So-Jung / Kang, Hwi-Joong / Lee, Ga-Young / Lee, Namhun / Park, Ji Hye / Yoo, Hwa-Seung

    Integrative cancer therapies

    2020  Volume 19, Page(s) 1534735420926583

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Combined Modality Therapy ; Disease-Free Survival ; Humans ; Hyperthermia ; Hyperthermia, Induced ; Neoplasms/therapy ; Prescriptions ; Retrospective Studies ; Temperature
    Language English
    Publishing date 2020-05-23
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2182320-0
    ISSN 1552-695X ; 1534-7354
    ISSN (online) 1552-695X
    ISSN 1534-7354
    DOI 10.1177/1534735420926583
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    Zs.A 6026: Show issues Location:
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  6. Article: Letter: Expression of Glucagon-Like Peptide-1 Receptor in Papillary Thyroid Carcinoma and Its Clinicopathologic Significance (Endocrinol Metab 2014;29:536-44, Min Jung Jung et al.).

    Park, Daeyoon / Lee, Eun Kyung

    Endocrinology and metabolism (Seoul, Korea)

    2015  Volume 30, Issue 2, Page(s) 231–232

    Language English
    Publishing date 2015-06
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2802452-7
    ISSN 2093-5978 ; 2093-596X
    ISSN (online) 2093-5978
    ISSN 2093-596X
    DOI 10.3803/EnM.2015.30.2.231
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    Full text online

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  7. Article ; Online: Compensatory structural and functional adaptation after radical nephrectomy for renal cell carcinoma according to preoperative stage of chronic kidney disease. Choi DK, Jung SB, Park BH, Jeong BC, Seo SI, Jeon SS, Lee HM, Choi HY, Jeon HG.J Urol. 2015 Oct;194(4):910-5. [Epub 2015 Apr 28]. doi: 10.1016/j.juro.2015.04.093.

    Jay, Raman / Jung, S B / Park, B H / Jeong, B C / Seo, S I / Jeon, S S / Lee, H M / Choi, H Y / Jeon, H G

    Urologic oncology

    2017  Volume 35, Issue 3, Page(s) 118–119

    Abstract: Purpose: We investigated structural hypertrophy and functional hyperfiltration as compensatory adaptations after radical nephrectomy in patients with renal cell carcinoma according to the preoperative chronic kidney disease stage.: Materials and ... ...

    Abstract Purpose: We investigated structural hypertrophy and functional hyperfiltration as compensatory adaptations after radical nephrectomy in patients with renal cell carcinoma according to the preoperative chronic kidney disease stage.
    Materials and methods: We retrospectively identified 543 patients who underwent radical nephrectomy for renal cell carcinoma between 1997 and 2012. Patients were classified according to preoperative glomerular filtration rate as no chronic kidney disease-glomerular filtration rate 90ml/min/1.73m
    Results: Among all patients (mean age = 56.0y) mean preoperative glomerular filtration rate, functional renal volume, and glomerular filtration rate/functional renal volume were 83.2ml/min/1.73m
    Conclusions: Patients with a lower preoperative glomerular filtration rate had a smaller reduction in postoperative renal function than those with a higher preoperative glomerular filtration rate due to greater degrees of functional hyperfiltration.
    Language English
    Publishing date 2017-02-01
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1336505-8
    ISSN 1873-2496 ; 1078-1439
    ISSN (online) 1873-2496
    ISSN 1078-1439
    DOI 10.1016/j.urolonc.2016.12.024
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4817: Show issues Location:
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  8. Article ; Online: Jageum-Jung improves 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in mice and suppresses pro-inflammatory chemokine production by inhibiting TNF-α/IFN-γ-induced STAT-1 and NFκB signaling in HaCaT cells.

    Yang, Ju-Hye / Do, Hyun Ju / Lee, Esther / Yim, Nam-Hui / Cho, Won-Kyung / Park, Kwang-Il / Ma, Jin Yeul

    Journal of ethnopharmacology

    2018  Volume 221, Page(s) 48–55

    Abstract: Ethnopharmacological relevance: Jageum-Jung (JGJ) is an oriental herbal formula comprising five ...

    Abstract Ethnopharmacological relevance: Jageum-Jung (JGJ) is an oriental herbal formula comprising five herbs (Melaphis chinensis Bell, Cremastra variabilis Nakai, Knoxia valerianoides Thorel, Euphorbia lathyris L., and Moschus moschiferus L.). It has been used for detoxification and treating cancer and inflammatory diseases in China, Japan, and Korea. However, the mechanism of action of JGJ on keratinocyte inflammatory response is poorly understood.
    Aim of the study: In the present study, we investigated the anti-inflammatory mechanism of JGJ and studied the effects of JGJ on atopic dermatitis-like skin lesions in mice.
    Materials and methods: We elucidated the anti-inflammatory and anti-inflammatory effects of JGJ on tumor necrosis factor-α/interferon-γ (TNF-α/IFN-γ)-treated human keratinocyte cells, IgE-sensitized RBL-2H3 cells, and 2,4-dinitrochlorobenzene (DNCB)-induced atopic dermatitis (AD)-like mice, respectively.
    Results: The results showed that JGJ suppressed the production and mRNA revels of IL-8, IL-6 and, conspicuously, both TARC and RANTES. JGJ inhibited nuclear translocation of the inflammatory transcription factors NFκB and STAT-1. Moreover, JGJ improved AD-like skin lesions in DNCB-treated mice and inhibited degranulation of mast cell.
    Conclusions: The results of this study suggest that JGJ can be considered as a candidate agent for AD treatment.
    MeSH term(s) Animals ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Cell Line ; Chemokine CCL5/metabolism ; Cytokines/genetics ; Cytokines/metabolism ; Dermatitis, Atopic/drug therapy ; Dermatitis, Atopic/metabolism ; Dermatitis, Atopic/pathology ; Dinitrochlorobenzene ; Humans ; Keratinocytes/drug effects ; Keratinocytes/metabolism ; Male ; Mice, Inbred BALB C ; Mitogen-Activated Protein Kinases/metabolism ; NF-kappa B/metabolism ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use ; STAT1 Transcription Factor/metabolism ; Skin/drug effects ; Skin/metabolism ; Skin/pathology
    Chemical Substances Anti-Inflammatory Agents ; Chemokine CCL5 ; Cytokines ; NF-kappa B ; Plant Extracts ; STAT1 Transcription Factor ; jageum-jung ; Mitogen-Activated Protein Kinases (EC 2.7.11.24) ; Dinitrochlorobenzene (GE3IBT7BMN)
    Language English
    Publishing date 2018-04-14
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2018.04.016
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    Zs.A 1494: Show issues Location:
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  9. Book ; Online: Lattice-Preferred Orientation and Microstructures of Minerals and Their Implications for Seismic Anisotropy

    Jung, Haemyeong / Park, Munjae / Park, Munjae

    2021  

    Keywords Research & information: general ; Environmental economics ; microstructural evolution ; lattice preferred orientation ; olivine in Åheim ; amphibole ; seismic anisotropy ; seismic velocity ; olivine-rich eclogite ; Western Gneiss Region ; glaucophane ; epidote ; deformation experiment ; simple shear ; dislocation glide ; cataclastic flow ; spinel peridotite xenoliths ; deformation microstructures ; petrogenesis ; mantle heterogeneity ; Baekdusan volcano ; Ice ; microstructure ; crystallographic preferred orientation (CPO) ; Styx Glacier ; electron backscatter diffraction (EBSD) ; Val Malenco ; serpentinized peridotite ; tectonic evolution ; deformation ; strain localization ; phyllite ; muscovite ; chlorite ; retrograded eclogite ; topotactic growth ; reflection coefficient ; omphacite ; subduction zone ; lattice-preferred orientation ; Xitieshan eclogite ; lawsonite ; twin ; blueschist ; crystal preferred orientation ; n/a
    Size 1 electronic resource (204 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel, Switzerland
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021289517
    ISBN 9783036526430 ; 3036526439
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  10. Article ; Online: Reply.

    Jung, Da Hyun / Park, Jun Chul

    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

    2024  

    Language English
    Publishing date 2024-01-05
    Publishing country United States
    Document type Letter
    ZDB-ID 2119789-1
    ISSN 1542-7714 ; 1542-3565
    ISSN (online) 1542-7714
    ISSN 1542-3565
    DOI 10.1016/j.cgh.2023.12.025
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    Zs.A 5836: Show issues Location:
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