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  1. Article: Bacillus coagulans: Monograph.

    Jurenka, Julie S

    Alternative medicine review : a journal of clinical therapeutic

    2012  Volume 17, Issue 1, Page(s) 76–81

    MeSH term(s) Animals ; Bacillus ; Biological Products/pharmacology ; Biological Products/therapeutic use ; Chronic Disease/drug therapy ; Humans ; Intestinal Diseases/drug therapy ; Intestinal Diseases/prevention & control ; Probiotics/pharmacology ; Probiotics/therapeutic use
    Chemical Substances Biological Products
    Language English
    Publishing date 2012-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1465535-4
    ISSN 1089-5159
    ISSN 1089-5159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research.

    Jurenka, Julie S

    Alternative medicine review : a journal of clinical therapeutic

    2009  Volume 14, Issue 2, Page(s) 141–153

    Abstract: Curcuma longa (turmeric) has a long history of use in Ayurvedic medicine as a treatment for inflammatory conditions. Turmeric constituents include the three curcuminoids: curcumin (diferuloylmethane; the primary constituent and the one responsible for ... ...

    Abstract Curcuma longa (turmeric) has a long history of use in Ayurvedic medicine as a treatment for inflammatory conditions. Turmeric constituents include the three curcuminoids: curcumin (diferuloylmethane; the primary constituent and the one responsible for its vibrant yellow color), demethoxycurcumin, and bisdemethoxycurcumin, as well as volatile oils (tumerone, atlantone, and zingiberone), sugars, proteins, and resins. While numerous pharmacological activities, including antioxidant and antimicrobial properties, have been attributed to curcumin, this article focuses on curcumin's anti-inflammatory properties and its use for inflammatory conditions. Curcumin's effect on cancer (from an anti-inflammatory perspective) will also be discussed; however, an exhaustive review of its many anticancer mechanisms is outside the scope of this article. Research has shown curcumin to be a highly pleiotropic molecule capable of interacting with numerous molecular targets involved in inflammation. Based on early cell culture and animal research, clinical trials indicate curcumin may have potential as a therapeutic agent in diseases such as inflammatory bowel disease, pancreatitis, arthritis, and chronic anterior uveitis, as well as certain types of cancer. Because of curcumin's rapid plasma clearance and conjugation, its therapeutic usefulness has been somewhat limited, leading researchers to investigate the benefits of complexing curcumin with other substances to increase systemic bioavailability. Numerous in-progress clinical trials should provide an even deeper understanding of the mechanisms and therapeutic potential of curcumin.
    MeSH term(s) Animals ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Autoimmune Diseases/drug therapy ; Cardiovascular Diseases/drug therapy ; Clinical Trials as Topic ; Curcuma ; Humans ; Inflammation/drug therapy ; Metabolic Diseases/drug therapy ; Neoplasms/drug therapy ; Neurodegenerative Diseases/drug therapy ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use
    Chemical Substances Anti-Inflammatory Agents ; Antineoplastic Agents ; Plant Extracts ; turmeric extract (856YO1Z64F)
    Language English
    Publishing date 2009-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1465535-4
    ISSN 1089-5159
    ISSN 1089-5159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Therapeutic applications of pomegranate (Punica granatum L.): a review.

    Jurenka, Julie S

    Alternative medicine review : a journal of clinical therapeutic

    2008  Volume 13, Issue 2, Page(s) 128–144

    Abstract: The pomegranate, Punica granatum L., is an ancient, mystical, unique fruit borne on a small, long-living tree cultivated throughout the Mediterranean region, as far north as the Himalayas, in Southeast Asia, and in California and Arizona in the United ... ...

    Abstract The pomegranate, Punica granatum L., is an ancient, mystical, unique fruit borne on a small, long-living tree cultivated throughout the Mediterranean region, as far north as the Himalayas, in Southeast Asia, and in California and Arizona in the United States. In addition to its ancient historical uses, pomegranate is used in several systems of medicine for a variety of ailments. The synergistic action of the pomegranate constituents appears to be superior to that of single constituents. In the past decade, numerous studies on the antioxidant, anticarcinogenic, and anti-inflammatory properties of pomegranate constituents have been published, focusing on treatment and prevention of cancer, cardiovascular disease, diabetes, dental conditions, erectile dysfunction, bacterial infections and antibiotic resistance, and ultraviolet radiation-induced skin damage. Other potential applications include infant brain ischemia, male infertility, Alzheimer's disease, arthritis, and obesity.
    MeSH term(s) Animals ; Antioxidants/pharmacokinetics ; Antioxidants/therapeutic use ; Ellagic Acid/pharmacokinetics ; Ellagic Acid/therapeutic use ; Female ; Humans ; Male ; Mice ; Phytotherapy ; Plant Extracts/pharmacokinetics ; Plant Extracts/therapeutic use ; Punicaceae/chemistry ; Rats
    Chemical Substances Antioxidants ; Plant Extracts ; Ellagic Acid (19YRN3ZS9P)
    Language English
    Publishing date 2008-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1465535-4
    ISSN 1089-5159
    ISSN 1089-5159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Inflammatory bowel disease. Part II: Crohn's disease--pathophysiology and conventional and alternative treatment options.

    Head, Kathleen / Jurenka, Julie S

    Alternative medicine review : a journal of clinical therapeutic

    2004  Volume 9, Issue 4, Page(s) 360–401

    Abstract: Crohn's disease, a subcategory of inflammatory bowel disease, contributes to significant morbidity, particularly in industrialized nations. It can affect people of any age, but is more commonly diagnosed in adolescence and young adulthood. Inflammation ... ...

    Abstract Crohn's disease, a subcategory of inflammatory bowel disease, contributes to significant morbidity, particularly in industrialized nations. It can affect people of any age, but is more commonly diagnosed in adolescence and young adulthood. Inflammation and ulceration occurs primarily in the terminal ileum and colon, although any portion of the intestinal tract can be affected. No etiology has been identified for Crohn's disease, although a number of factors contribute to its etiopathogenesis, including genetic, microbial, inflammatory, immune, and permeability abnormalities. Conventional medications are not curative but can contribute to resolution of acute flare-ups and help maintain remission. Because significant side effects are associated with many these medications, more natural interventions to help maintain remission should be considered. Associated nutrient deficiencies, dietary interventions, and nutrient and botanical supplementation are discussed.
    MeSH term(s) Crohn Disease/diagnosis ; Crohn Disease/etiology ; Crohn Disease/therapy ; Humans ; Intestine, Small/physiopathology ; Permeability ; Risk Factors
    Language English
    Publishing date 2004-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1465535-4
    ISSN 1089-5159
    ISSN 1089-5159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Inflammatory bowel disease Part 1: ulcerative colitis--pathophysiology and conventional and alternative treatment options.

    Head, Kathleen A / Jurenka, Julie S

    Alternative medicine review : a journal of clinical therapeutic

    2003  Volume 8, Issue 3, Page(s) 247–283

    Abstract: Ulcerative colitis (UC), a subcategory of inflammatory bowel disease, afflicts 1-2 million people in the United States, and many more worldwide. Although the exact cause of ulcerative colitis remains undetermined, the condition appears to be related to a ...

    Abstract Ulcerative colitis (UC), a subcategory of inflammatory bowel disease, afflicts 1-2 million people in the United States, and many more worldwide. Although the exact cause of ulcerative colitis remains undetermined, the condition appears to be related to a combination of genetic and environmental factors. While conventional treatments can be effective in maintaining remission and decreasing the length of active disease periods, the treatments are not without side effects, and a significant number of people suffering from UC fail to respond to even the strongest drugs. This article reviews potential unconventional treatments - transdermal nicotine, heparin, melatonin, DHEA, probiotics, fiber, dietary changes, botanicals, essential fatty acids, and other nutrients - that may be considered in conjunction with conventional approaches or as part of a comprehensive alternative treatment protocol. In addition this review addresses risk factors, pathogenesis, nutrient deficiencies, conventional treatment approaches, and extra-intestinal manifestations of the disease.
    MeSH term(s) Butyric Acid/metabolism ; Colitis, Ulcerative/etiology ; Colitis, Ulcerative/microbiology ; Colitis, Ulcerative/therapy ; Diet ; Elements ; Fatty Acids/administration & dosage ; Humans ; Nicotine/therapeutic use ; Nicotinic Agonists/therapeutic use ; Oxidative Stress ; Probiotics ; Smoking ; Sulfur/metabolism ; Vitamins/therapeutic use
    Chemical Substances Elements ; Fatty Acids ; Nicotinic Agonists ; Vitamins ; Butyric Acid (107-92-6) ; Nicotine (6M3C89ZY6R) ; Sulfur (70FD1KFU70)
    Language English
    Publishing date 2003-08
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1465535-4
    ISSN 1089-5159
    ISSN 1089-5159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Colds and influenza: a review of diagnosis and conventional, botanical, and nutritional considerations.

    Roxas, Mario / Jurenka, Julie

    Alternative medicine review : a journal of clinical therapeutic

    2007  Volume 12, Issue 1, Page(s) 25–48

    Abstract: ... in 189 million lost school days. In the course of one year the U.S. population contracts approximately 1 ...

    Abstract The common cold is the leading cause of doctor visits in the United States and annually results in 189 million lost school days. In the course of one year the U.S. population contracts approximately 1 billion colds. Influenza infection is still a leading cause of morbidity and mortality, accounting for 20-25 million doctor visits and 36,000 deaths per year in the United States. Conventional therapies for colds and flu focus primarily on temporary symptom relief and include over-the-counter antipyretics, anti-inflammatories, and decongestants. Treatment for influenza also includes prescription antiviral agents and vaccines for prevention. This article reviews the common cold and influenza viruses, presents the conventional treatment options, and highlights select botanicals (Echinacea spp., Sambucus nigra, larch arabinogalactan, Astragalus membranaceous, Baptisia tinctoria, Allium sativa, Panax quinquefolium, Eleutherococcus senticosus, Andrographis paniculata, olive leaf extract, and Isatis tinctoria) and nutritional considerations (vitamins A and C, zinc, high lactoferrin whey protein, N-acetylcysteine, and DHEA) that may help in the prevention and treatment of these conditions.
    MeSH term(s) Acetylcysteine/therapeutic use ; Antiviral Agents/therapeutic use ; Common Cold/complications ; Common Cold/therapy ; Common Cold/virology ; Dehydroepiandrosterone/therapeutic use ; Humans ; Influenza Vaccines/therapeutic use ; Influenza, Human/complications ; Influenza, Human/therapy ; Influenza, Human/virology ; Lactoferrin/therapeutic use ; Nonprescription Drugs/therapeutic use ; Phytotherapy/methods ; Zinc/therapeutic use
    Chemical Substances Antiviral Agents ; Influenza Vaccines ; Nonprescription Drugs ; Dehydroepiandrosterone (459AG36T1B) ; Lactoferrin (EC 3.4.21.-) ; Zinc (J41CSQ7QDS) ; Acetylcysteine (WYQ7N0BPYC)
    Keywords covid19
    Language English
    Publishing date 2007-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1465535-4
    ISSN 1089-5159
    ISSN 1089-5159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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