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  1. Article: Re: porcine small intestinal submucosa is not an ideal graft material for Peyronie's disease surgery. T. John, G. Bandi and R. Santucci J Urol 2006; 176: 1025-1029.

    Knoll, L Dean

    The Journal of urology

    2007  Volume 177, Issue 3, Page(s) 1204

    MeSH term(s) Humans ; Intestinal Mucosa/transplantation ; Intestine, Small/transplantation ; Male ; Penile Induration/surgery ; Treatment Outcome
    Language English
    Publishing date 2007-03
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1016/j.juro.2006.10.096
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A Report of Cases Treated with Gonococcus Vaccine.

    Knoll, J G W

    Buffalo medical journal

    2023  Volume 67, Issue 10, Page(s) 550

    Language English
    Publishing date 2023-03-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 426473-3
    ISSN 1040-3817
    ISSN 1040-3817
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Sex in a dish: high-efficiency Toxoplasma pre-sexual development.

    Hryckowian, Nicole D / Knoll, Laura J

    Trends in parasitology

    2024  Volume 40, Issue 3, Page(s) 209–210

    Abstract: Antunes et al. successfully grew cat-restricted stages of Toxoplasma gondii in cell culture by targeting parasite epigenetics and transcription factors. The highlight of this report is how efficiently parasites convert to these pre-sexual stages. Their ... ...

    Abstract Antunes et al. successfully grew cat-restricted stages of Toxoplasma gondii in cell culture by targeting parasite epigenetics and transcription factors. The highlight of this report is how efficiently parasites convert to these pre-sexual stages. Their work is an important step toward achieving feline-free recapitulation of the T. gondii sexual cycle.
    MeSH term(s) Cats ; Animals ; Toxoplasma/genetics ; Parasites ; Sexual Development
    Language English
    Publishing date 2024-02-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2036227-4
    ISSN 1471-5007 ; 1471-4922
    ISSN (online) 1471-5007
    ISSN 1471-4922
    DOI 10.1016/j.pt.2024.01.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Spatial localization during open-loop smooth pursuit.

    Dowiasch, Stefan / Blanke, Marius / Knöll, Jonas / Bremmer, Frank

    Frontiers in neuroscience

    2023  Volume 17, Page(s) 1058340

    Abstract: Introduction: Numerous previous studies have shown that eye movements induce errors in the localization of briefly flashed stimuli. Remarkably, the error pattern is indicative of the underlying eye movement and the exact experimental condition. For ... ...

    Abstract Introduction: Numerous previous studies have shown that eye movements induce errors in the localization of briefly flashed stimuli. Remarkably, the error pattern is indicative of the underlying eye movement and the exact experimental condition. For smooth pursuit eye movements (SPEM) and the slow phase of the optokinetic nystagmus (OKN), perceived stimulus locations are shifted in the direction of the ongoing eye movement, with a hemifield asymmetry observed only during SPEM. During the slow phases of the optokinetic afternystagmus (OKAN), however, the error pattern can be described as a perceptual expansion of space. Different from SPEM and OKN, the OKAN is an open-loop eye movement.
    Methods: Visually guided smooth pursuit can be transformed into an open-loop eye movement by briefly blanking the pursuit target (gap). Here, we examined flash localization during open-loop pursuit and asked, whether localization is also prone to errors and whether these are similar to those found during SPEM or during OKAN. Human subjects tracked a pursuit target. In half of the trials, the target was extinguished for 300 ms (gap) during the steady-state, inducing open-loop pursuit. Flashes were presented during this gap or during steady-state (closed-loop) pursuit.
    Results: In both conditions, perceived flash locations were shifted in the direction of the eye movement. The overall error pattern was very similar with error size being slightly smaller in the gap condition. The differences between errors in the open- and closed-loop conditions were largest in the central visual field and smallest in the periphery.
    Discussion: We discuss the findings in light of the neural substrates driving the different forms of eye movements.
    Language English
    Publishing date 2023-02-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2411902-7
    ISSN 1662-453X ; 1662-4548
    ISSN (online) 1662-453X
    ISSN 1662-4548
    DOI 10.3389/fnins.2023.1058340
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: Die Freiheit des Selbst

    Novick, Jack / Novick, Kerry Kelly / Knoll, Eberhard

    Zwei Systeme der Selbstregulation in der psychodynamischen Therapie und der Persönlichkeitsentwicklung

    2019  

    Keywords SPSAA ; SPSBC ; SPSBT ; SPSP055 ; Psychoanalyse ; Selbstregulation ; Persönlichkeitsentwicklung
    Language German
    Size 235 p.
    Edition 1
    Publisher Brandes & Apsel Verlag
    Document type Book
    Note PDA Manuell_3
    Format 154 x 235 x 17
    ISBN 9783955582609 ; 3955582604
    Database PDA

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  6. Article ; Online: Epidemiology of Cancer in Kidney Transplant Recipients.

    Massicotte-Azarniouch, David / Noel, J Ariana / Knoll, Greg A

    Seminars in nephrology

    2024  , Page(s) 151494

    Abstract: Kidney transplantation is the ideal treatment modality for patients with end-stage kidney disease, with excellent outcomes post-transplant compared with dialysis. However, kidney transplant recipients are at increased risk of infections and cancer ... ...

    Abstract Kidney transplantation is the ideal treatment modality for patients with end-stage kidney disease, with excellent outcomes post-transplant compared with dialysis. However, kidney transplant recipients are at increased risk of infections and cancer because of the need for immunosuppression. Kidney transplant recipients have approximately two to three times greater risk of developing cancer than the general population, and cancer is a major contributor to morbidity and mortality. Most of the increased risk is driven by viral-mediated cancers such as post-transplant lymphoproliferative disorder, anogenital cancers, and Kaposi sarcoma. Nonmelanoma skin cancer is the most frequent type of cancer in kidney transplant recipients, likely due to an interaction between ultraviolet radiation exposure and decreased immune surveillance. Occurrence of the more common types of solid organ cancers seen in the general population, such as breast, prostate, lung, and colorectal cancers, is not, or is only mildly, increased post-transplant. Clinical care and future research should focus on prevention and on improving outcomes for important immunosuppression-related malignancies, and treatment options for other cancers occurring in the transplant setting. Semin Nephrol 36:x-xx © 20XX Elsevier Inc. All rights reserved.
    Language English
    Publishing date 2024-03-26
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 604652-6
    ISSN 1558-4488 ; 0270-9295
    ISSN (online) 1558-4488
    ISSN 0270-9295
    DOI 10.1016/j.semnephrol.2024.151494
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Analysis of the Machine-Specific Behavior of Injection Molding Machines.

    Knoll, Julia / Heim, Hans-Peter

    Polymers

    2023  Volume 16, Issue 1

    Abstract: The performance of an injection molding machine (IMM) influences the process and the quality of the parts manufactured. Despite increasing data collection capabilities, their machine-specific behavior has not been extensively studied. To close ... ...

    Abstract The performance of an injection molding machine (IMM) influences the process and the quality of the parts manufactured. Despite increasing data collection capabilities, their machine-specific behavior has not been extensively studied. To close corresponding research gaps, the machine-specific behavior of two hydraulic IMMs of different sizes and one electric IMM were compared with each other as part of the investigations. Both the start-up behavior from the cold state and the behavior of the machine at different operating points were considered. To complement this, the influence of various material properties on the machine-specific behavior was investigated by processing an unreinforced and glass-fiber-reinforced polyamide. The results obtained provide crucial insights into machine-specific behavior, which may, for instance, account for disparities between computer fluid dynamic (CFD) simulations and experimental results. Furthermore, it is expected that the description of the machine-specific behavior can contribute to transfer knowledge when applying transfer learning algorithms. Looking ahead to future research, it is advised to create what is referred to as a "machine fingerprint", and this proposal is accompanied by some preliminary recommendations for its development.
    Language English
    Publishing date 2023-12-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym16010054
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: SRF deletion results in earlier disease onset in a mouse model of amyotrophic lateral sclerosis.

    Song, Jialei / Dikwella, Natalie / Sinske, Daniela / Roselli, Francesco / Knöll, Bernd

    JCI insight

    2023  Volume 8, Issue 15

    Abstract: Changes in neuronal activity modulate the vulnerability of motoneurons (MNs) in neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). So far, the molecular basis of neuronal activity's impact in ALS is poorly understood. Herein, we ... ...

    Abstract Changes in neuronal activity modulate the vulnerability of motoneurons (MNs) in neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). So far, the molecular basis of neuronal activity's impact in ALS is poorly understood. Herein, we investigated the impact of deleting the neuronal activity-stimulated transcription factor (TF) serum response factor (SRF) in MNs of SOD1G93A mice. SRF was present in vulnerable MMP9+ MNs. Ablation of SRF in MNs induced an earlier disease onset starting around 7-8 weeks after birth, as revealed by enhanced weight loss and decreased motor ability. This earlier disease onset in SRF-depleted MNs was accompanied by a mild elevation of neuroinflammation and neuromuscular synapse degeneration, whereas overall MN numbers and mortality were unaffected. In SRF-deficient mice, MNs showed impaired induction of autophagy-encoding genes, suggesting a potentially new SRF function in transcriptional regulation of autophagy. Complementary, constitutively active SRF-VP16 enhanced autophagy-encoding gene transcription and autophagy progression in cells. Furthermore, SRF-VP16 decreased ALS-associated aggregate induction. Chemogenetic modulation of neuronal activity uncovered SRF as having important TF-mediating activity-dependent effects, which might be beneficial to reduce ALS disease burden. Thus, our data identify SRF as a gene regulator connecting neuronal activity with the cellular autophagy program initiated in degenerating MNs.
    MeSH term(s) Animals ; Mice ; Amyotrophic Lateral Sclerosis/genetics ; Etoposide ; Gene Expression Regulation ; Motor Neurons/physiology ; Serum Response Factor/genetics
    Chemical Substances Etoposide (6PLQ3CP4P3) ; Serum Response Factor ; Srf protein, mouse
    Language English
    Publishing date 2023-08-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2379-3708
    ISSN (online) 2379-3708
    DOI 10.1172/jci.insight.167694
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book: The brain and its self

    Knoll, Joseph

    a neurochemical concept of the innate and acquired drives ; with 14 tables

    2005  

    Author's details Joseph Knoll
    Keywords Gehirn ; Trieb ; Neurochemie
    Subject Biochemie ; Neurobiochemie ; Triebe ; Cerebrum ; Hirn ; Encephalon ; Enzephalon ; Hirngewebe ; Hirnmasse ; Gehirnmasse
    Language English
    Size XII, 176 S. : Ill., graph. Darst., 235 mm x 155 mm
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT014407757
    ISBN 978-3-540-23969-7 ; 3-540-23969-3
    Database Catalogue ZB MED Medicine, Health

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  10. Article ; Online: Spatial localization during open-loop smooth pursuit

    Dowiasch, Stefan / Blanke, Marius / Knöll, Jonas / Bremmer, Frank

    2023  

    Abstract: Introduction: Numerous previous studies have shown that eye movements induce errors in the localization of briefly flashed stimuli. Remarkably, the error pattern is indicative of the underlying eye movement and the exact experimental condition. For ... ...

    Abstract Introduction: Numerous previous studies have shown that eye movements induce errors in the localization of briefly flashed stimuli. Remarkably, the error pattern is indicative of the underlying eye movement and the exact experimental condition. For smooth pursuit eye movements (SPEM) and the slow phase of the optokinetic nystagmus (OKN), perceived stimulus locations are shifted in the direction of the ongoing eye movement, with a hemifield asymmetry observed only during SPEM. During the slow phases of the optokinetic afternystagmus (OKAN), however, the error pattern can be described as a perceptual expansion of space. Different from SPEM and OKN, the OKAN is an open-loop eye movement. Methods: Visually guided smooth pursuit can be transformed into an open–loop eye movement by briefly blanking the pursuit target (gap). Here, we examined flash localization during open-loop pursuit and asked, whether localization is also prone to errors and whether these are similar to those found during SPEM or during OKAN. Human subjects tracked a pursuit target. In half of the trials, the target was extinguished for 300 ms (gap) during the steady–state, inducing open–loop pursuit. Flashes were presented during this gap or during steady–state (closed–loop) pursuit. Results: In both conditions, perceived flash locations were shifted in the direction of the eye movement. The overall error pattern was very similar with error size being slightly smaller in the gap condition. The differences between errors in the open- and closed-loop conditions were largest in the central visual field and smallest in the periphery. Discussion: We discuss the findings in light of the neural substrates driving the different forms of eye movements.
    Keywords Text ; ddc:570 ; smooth eye movements -- smooth pursuit -- localization -- open-loop eye movement -- open-loop SPEM -- localization error
    Subject code 629
    Language English
    Publishing date 2023-02-02
    Publisher Frontiers Media SA
    Publishing country de
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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