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  1. Article: Poultry Gastrointestinal-derived Lactic Acid Bacteria (pGIT-d-LAB) Inhibit Multiple Antibiotics Resistance Bacterial and Fungal Pathogens.

    Adeniyi, Bolanle / Adesuyi, Abimbola / Ayeni, Funmilola / Ogunbanwo, Temitope / Agidigbi, Taiwo

    Avicenna journal of medical biotechnology

    2024  Volume 16, Issue 2, Page(s) 111–119

    Abstract: Background: To develop a probiotic formulation for poultry feed, a few poultry gastrointestinal derived lactic acid bacteria (pGIT-d-LAB) were isolated from chicken intestinal specimens and : Methods: A total of 6 strains of LAB: : Results: The ... ...

    Abstract Background: To develop a probiotic formulation for poultry feed, a few poultry gastrointestinal derived lactic acid bacteria (pGIT-d-LAB) were isolated from chicken intestinal specimens and
    Methods: A total of 6 strains of LAB:
    Results: The observed results revealed that the CFS derived from the isolates exhibited varying degrees of growth inhibition against different pathogens. Among the tested pGIT-d-LAB isolates,
    Conclusion: The test isolates are potential probiotic candidates for controlling pathogens in poultry.
    Language English
    Publishing date 2024-04-11
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2520683-7
    ISSN 2008-4625 ; 2008-2835
    ISSN (online) 2008-4625
    ISSN 2008-2835
    DOI 10.18502/ajmb.v16i2.14862
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Beyond COVID-19: Turning Crisis to Opportunity in Nigeria through Urban Agriculture

    Gbadegesin, Adeniyi / Olajiire-Ajayi, Bolanle

    Journal of agriculture, food systems, and community development. 2020 Aug. 26, v. 9, no. 4

    2020  

    Abstract: Since the outbreak of the novel coronavirus (COVID-19) all over the world, countries have tried several strategies to minimize its impacts on their citizens and the economy. The first case in Nigeria was reported on February 27, 2020, and since then the ... ...

    Abstract Since the outbreak of the novel coronavirus (COVID-19) all over the world, countries have tried several strategies to minimize its impacts on their citizens and the economy. The first case in Nigeria was reported on February 27, 2020, and since then the infection has been spreading like wildfire, making Nigeria one of the three most affected African countries in Africa and the most affected in West Africa (Food and Agriculture Organization of the United Nations [FAO], 2020-a). To slow down its pace, governments at all levels have taken measures to curb its impacts. Measures taken include mandating social distancing, curfews, and, in some cases, complete lockdowns. The lockdown of virtually all sectors of the economy, especially the agricultural sector, has exacerbated food shortages in the country, espe­cially among urban dwellers. Unfortunately, agriculture in most developing countries is highly related to physical, rather than mechanized, labor. The labor shortage due to movement restrictions (both intra- and interstate) and social distancing as a result of COVID-19 are starting to affect agricultural producers in the hinterlands, thus worsening the food supply to urban centers that are coincidentally the epicenters of the disease.
    Keywords Coronavirus infections ; Food and Agriculture Organization ; Orthocoronavirinae ; agricultural industry ; community development ; developing countries ; food availability ; food shortages ; hinterland ; infection ; labor ; urban agriculture ; wildfires ; Nigeria
    Language English
    Dates of publication 2020-0826
    Size p. 171-174.
    Publishing place New Leaf Associates, Inc.
    Document type Article
    Note NAL-light
    ZDB-ID 2676287-0
    ISSN 2152-0801
    ISSN 2152-0801
    DOI 10.5304/jafscd.2020.094.033
    Database NAL-Catalogue (AGRICOLA)

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  3. Book: Microbes

    Adeniyi, Bolanle A

    culprits and their attackers on nature's field : an inaugural lecture delivered at the University of Ibadan on Thursday, 30 May, 2013

    (Inaugural lecture ; 2012/2013)

    2013  

    Institution University of Ibadan,
    Author's details by Bolanle A. Adeniyi
    Series title Inaugural lecture ; 2012/2013
    MeSH term(s) Anti-Infective Agents ; Microbiological Phenomena ; Plants, Medicinal ; Ethnopharmacology
    Keywords Nigeria
    Language English
    Size 82 pages :, illustrations.
    Document type Book
    ISBN 9789788456179 ; 9788456170
    Database Catalogue of the US National Library of Medicine (NLM)

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  4. Article ; Online: Pattern of admissions and outcome in the children emergency department of a tertiary health institution in Southwestern Nigeria: A four-year review.

    Agbesanwa, Tosin Anthony / Babatola, Adefunke Olarinre / Fatunla, Odunayo Adebukola / Ibrahim, Azeez / Aina, Felix O / Ogundare, Ezra Olatunde / Adeniyi, Adewuyi Temidayo / Egbedi, Funmilayo / Olubamiwa, Tinu / Olanipekun, Bolanle / Olatunya, Oladele Simeon

    African journal of emergency medicine : Revue africaine de la medecine d'urgence

    2023  Volume 13, Issue 2, Page(s) 45–51

    Abstract: Introduction: Pediatrics and adolescents are susceptible to illnesses that often necessitate emergency attention. Morbidity and mortality from illnesses in these ages have attracted much interest globally, particularly in Africa. Knowledge of pattern ... ...

    Abstract Introduction: Pediatrics and adolescents are susceptible to illnesses that often necessitate emergency attention. Morbidity and mortality from illnesses in these ages have attracted much interest globally, particularly in Africa. Knowledge of pattern and outcomes of admissions may guide policy and interventions especially in resource constrained settings. The study aimed to determine the pattern of admissions, outcomes and seasonal variations of conditions that presented at the children emergency of a tertiary health institution over a four-year period.
    Methods: A retrospective descriptive study of children emergency admissions from January 2016 to December 2019. Information obtained included age, diagnosis, month and year of admission, and outcome. Descriptive statistics were used to describe the demographic characteristics and Chi-squared test to assess their associations with the diagnoses made.
    Results: There were 3,223 admissions. There were more males (1866; 57.9%) and more toddlers (1181; 36.6%). The highest number of admissions were observed in the year 2018 (951; 29.6%) and during the wet season (1962; 60.9%). There was an overall mortality rate of 7%; complicated malaria, gastroenteritis and meningitis were the leading causes of death. Malaria (χ2 = 135.522, p value < 0.001), and gastroenteritis (χ2 = 130.883, p value < 0.001) were predominant among the toddlers while sepsis (χ2 = 71.530, p value < 0.001) and pneumonia (χ2 = 133.739, p value < 0.001) were more among the infants. Typhoid enteritis (χ2 = 26.629, p value < 0.001) and HIV (χ2 = 16.419, p value = 0.012) were commoner among the early adolescents.
    Conclusion: The major causes of death in the study area are preventable with more of these amongst the children under the age of 5 years. There are seasonal and age-related patterns to admissions and the need for policy formulations and emergency preparations to be tailored towards these observed patterns through the year.
    Language English
    Publishing date 2023-02-18
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2211-4203
    ISSN (online) 2211-4203
    DOI 10.1016/j.afjem.2023.02.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Characterization and anti-salmonella activities of lactic acid bacteria isolated from cattle faeces.

    Adetoye, Adewale / Pinloche, Eric / Adeniyi, Bolanle A / Ayeni, Funmilola A

    BMC microbiology

    2018  Volume 18, Issue 1, Page(s) 96

    Abstract: Background: Non typhoidal salmonellosis is one of the neglected zoonoses in most African countries. The use of sub-therapeutic doses of antibiotics as animal growth promoter enhances the emergence and dissemination of antimicrobial resistance in ... ...

    Abstract Background: Non typhoidal salmonellosis is one of the neglected zoonoses in most African countries. The use of sub-therapeutic doses of antibiotics as animal growth promoter enhances the emergence and dissemination of antimicrobial resistance in bacteria with food animal reservoirs and may also results in antibiotics residue in animal products. One promising alternative to antibiotics in animal feed is Lactic Acid Bacteria (LAB) as probiotics. This study was carried out to determine the anti-salmonella activities and suitability of LAB isolated from cattle faeces in Nigeria as potential probiotics in cattle feed.
    Method: The test Salmonella enterica spp strains and LAB were isolated from cattle faeces and identified by MALDI-TOF MS and partial sequencing of 16S rRNA genes respectively. The anti-salmonella activities of the isolated LAB in co-culture, cell-free supernatant, inhibition of growth by viable LAB cells and quantification of organic acids were determined by standard techniques. The ability of the LAB strains to withstand gastric conditions, antibiotic susceptibility and their haemolytic ability on blood agar were also determined.
    Results: A total of 88 LAB belonging to 15 species were isolated and identified from cattle faeces. The most abundant species were Streptococcus infantarius (26), Enterococcus hirae (12), Lactobacillus amylovorus (10), Lactobacillus mucosae (10) and Lactobacillus ingluviei (9). Most of the LAB strains showed good anti-salmonella activities against the test Salmonella enterica spp. with 2 Lactobacillus strains; Lactobacillus amylovorus C94 and Lactobacillus salivarius C86 exhibiting remarkable anti-salmonella activities with total inhibition of Salmonella spp after 18 hours of co-incubation. The selected strains were able to survive simultaneous growth at pH 3 and 7% bile concentration and are non hemolytic.
    Conclusion: This study reports the vast diversity of culturable LAB in cattle faeces from Nigeria and their putative in-vitro antibacterial activity against Salmonella enterica spp isolated from cattle. Lactobacillus amylovorus C94 and Lactobacillus salivarius C86 demonstrated promising probiotic potentials in-vitro and will be further tested in-vivo in animal field trial.
    MeSH term(s) Acclimatization ; Animal Feed ; Animals ; Anti-Bacterial Agents/pharmacology ; Antibiosis ; Bile ; Cattle ; Coculture Techniques ; Feces/microbiology ; Hydrogen-Ion Concentration ; Kinetics ; Lactobacillales/drug effects ; Lactobacillales/genetics ; Lactobacillales/isolation & purification ; Lactobacillales/physiology ; Microbial Sensitivity Tests ; Nigeria ; Probiotics/pharmacology ; RNA, Ribosomal, 16S/genetics ; Salmonella/growth & development ; Salmonella/isolation & purification ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods
    Chemical Substances Anti-Bacterial Agents ; RNA, Ribosomal, 16S
    Language English
    Publishing date 2018-08-30
    Publishing country England
    Document type Journal Article
    ISSN 1471-2180
    ISSN (online) 1471-2180
    DOI 10.1186/s12866-018-1248-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Occurrence of aminoglycoside-modifying enzymes genes (aac(6')-I and ant(2″)-I) in clinical isolates of Pseudomonas aeruginosa from Southwest Nigeria.

    Odumosu, Bamidele Tolulope / Adeniyi, Bolanle A / Chandra, Ram

    African health sciences

    2016  Volume 15, Issue 4, Page(s) 1277–1281

    Abstract: Background: Enzymatic modification of aminoglycosides is the primary mechanism of resistance by Pseudomonas aeruginosa.: Obejectives: We investigated the occurrence and mechanism of aminoglycosides resistance in P. aeruginosa isolates from hospitals ... ...

    Abstract Background: Enzymatic modification of aminoglycosides is the primary mechanism of resistance by Pseudomonas aeruginosa.
    Obejectives: We investigated the occurrence and mechanism of aminoglycosides resistance in P. aeruginosa isolates from hospitals in SouthWest Nigeria.
    Methods: A total of 54 consecutive, non-duplicate clinical isolates of P. aeruginosa were studied for the presence of aminoglycosides -modifying enzymes (AMEs) by PCR amplification and sequencing of genes encoding AMEs.
    Results and conclusion: Two types of AME genes [aac (6') - I and ant (2″) - I] were found in 12 isolates out of 54. Seven strains harboured one or more types of enzymes of which aac (6') - I was the most frequently found gene (10/54 isolates, 18.5%). None of the isolates investigated in this study were positive for aph, aac (3) and aac (6″) - II genes. Prevalence of P. aeruginosa producing AME genes in this study may suggest aminoglycosides use in Nigeria. This study highlights need for functional antimicrobial surveillance system in Nigeria.
    MeSH term(s) Acetyltransferases/genetics ; Aminoglycosides/metabolism ; Aminoglycosides/pharmacology ; Anti-Bacterial Agents/metabolism ; Anti-Bacterial Agents/pharmacology ; DNA, Bacterial/genetics ; Drug Resistance, Bacterial/drug effects ; Drug Resistance, Bacterial/genetics ; Hospitals ; Humans ; Microbial Sensitivity Tests ; Nigeria ; Polymerase Chain Reaction ; Pseudomonas aeruginosa/drug effects ; Pseudomonas aeruginosa/genetics ; Pseudomonas aeruginosa/isolation & purification
    Chemical Substances Aminoglycosides ; Anti-Bacterial Agents ; DNA, Bacterial ; Acetyltransferases (EC 2.3.1.-) ; aminoglycoside acetyltransferase (EC 2.3.1.-)
    Language English
    Publishing date 2016-03-09
    Publishing country Uganda
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2240308-5
    ISSN 1729-0503 ; 1680-6905
    ISSN (online) 1729-0503
    ISSN 1680-6905
    DOI 10.4314/ahs.v15i4.29
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3851: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  7. Article: A randomized, open-label trial of combined nitazoxanide and atazanavir/ritonavir for mild to moderate COVID-19.

    Fowotade, Adeola / Bamidele, Folasade / Egbetola, Boluwatife / Fagbamigbe, Adeniyi F / Adeagbo, Babatunde A / Adefuye, Bolanle O / Olagunoye, Ajibola / Ojo, Temitope O / Adebiyi, Akindele O / Olagunju, Omobolanle I / Ladipo, Olabode T / Akinloye, Abdulafeez / Onayade, Adedeji / Bolaji, Oluseye O / Rannard, Steve / Happi, Christian / Owen, Andrew / Olagunju, Adeniyi

    Frontiers in medicine

    2022  Volume 9, Page(s) 956123

    Abstract: Background: The nitazoxanide plus atazanavir/ritonavir for COVID-19 (NACOVID) trial investigated the efficacy and safety of repurposed nitazoxanide combined with atazanavir/ritonavir for COVID-19.: Methods: This is a pilot, randomized, open-label ... ...

    Abstract Background: The nitazoxanide plus atazanavir/ritonavir for COVID-19 (NACOVID) trial investigated the efficacy and safety of repurposed nitazoxanide combined with atazanavir/ritonavir for COVID-19.
    Methods: This is a pilot, randomized, open-label multicenter trial conducted in Nigeria. Mild to moderate COVID-19 patients were randomly assigned to receive standard of care (SoC) or SoC plus a 14-day course of nitazoxanide (1,000 mg b.i.d.) and atazanavir/ritonavir (300/100 mg od) and followed through day 28. Study endpoints included time to clinical improvement, SARS-CoV-2 viral load change, and time to complete symptom resolution. Safety and pharmacokinetics were also evaluated (ClinicalTrials.gov ID: NCT04459286).
    Results: There was no difference in time to clinical improvement between the SoC (
    Conclusion: Nitazoxanide co-administered with atazanavir/ritonavir was safe but not better than standard of care in treating COVID-19. These findings should be interpreted in the context of incomplete enrollment (64%) and the limited number of patients with detectable SARS-CoV-2 in saliva at baseline in this trial.
    Clinical trial registration: [https://clinicaltrials.gov/ct2/show/NCT04459286], identifier [NCT04459286].
    Language English
    Publishing date 2022-09-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2022.956123
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Antibacterial activities of lactic acid bacteria isolated from cow faeces against potential enteric pathogens.

    Adeniyi, Bolanle A / Adetoye, Adewale / Ayeni, Funmilola A

    African health sciences

    2015  Volume 15, Issue 3, Page(s) 888–895

    Abstract: Background: The addition of sub therapeutic doses of antibiotics to cattle feed for growth promotion is a contributory factor to antibiotic resistance, thus an alternative to antibiotics is needed in animal feed additives.: Objective: To determine ... ...

    Abstract Background: The addition of sub therapeutic doses of antibiotics to cattle feed for growth promotion is a contributory factor to antibiotic resistance, thus an alternative to antibiotics is needed in animal feed additives.
    Objective: To determine the antimicrobial activity of cow's intestinal Lactic acid bacteria (LAB) against enteric commensals.
    Method: Escherichia coli, Klebsiella species (spp) and LAB were isolated from thirty different cow faecal samples and the LAB identified by partial sequencing of 16S rRNA. The antimicrobial activity of the LAB was determined against the test Escherichia coli and Klebsiella spp.
    Results: Five species of LAB were isolated from thirty cow faecal samples and identified as Enterococcus hirae (8), Enterococcus durans (6), Enterococcus faecium (1), Enterococcus faecalis (1) and Weissella confusa (1). Viable cells and cell free supernatant (CFS) of the LAB were able to inhibit the growth of the test organisms with the largest zone of inhibition by the viable cells being 26mm against Escherichia coli CB6 produced by Enterococcus hirae CO6A while Weissella confusa CO29M and Enterococcus hirae CO2A produced the largest zones of inhibition (26mm) against Klebsiella CB2.
    Conclusion: This study shows that LAB from cow faeces possess considerable antimicrobial activity against resistant Escherichia coli from the same environment.
    MeSH term(s) Animals ; Anti-Bacterial Agents/pharmacology ; Cattle ; Drug Resistance, Microbial ; Enterococcus ; Escherichia coli/drug effects ; Escherichia coli/genetics ; Escherichia coli/isolation & purification ; Feces/microbiology ; Female ; Humans ; Klebsiella/drug effects ; Klebsiella/isolation & purification ; Lactic Acid/pharmacology ; Meat/microbiology ; RNA, Ribosomal, 16S
    Chemical Substances Anti-Bacterial Agents ; RNA, Ribosomal, 16S ; Lactic Acid (33X04XA5AT)
    Language English
    Publishing date 2015-09
    Publishing country Uganda
    Document type Journal Article
    ZDB-ID 2240308-5
    ISSN 1729-0503 ; 1680-6905
    ISSN (online) 1729-0503
    ISSN 1680-6905
    DOI 10.4314/ahs.v15i3.24
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3851: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: A randomized, open-label trial of combined nitazoxanide and atazanavir/ritonavir for mild to moderate COVID-19

    Adeola Fowotade / Folasade Bamidele / Boluwatife Egbetola / Adeniyi F. Fagbamigbe / Babatunde A. Adeagbo / Bolanle O. Adefuye / Ajibola Olagunoye / Temitope O. Ojo / Akindele O. Adebiyi / Omobolanle I. Olagunju / Olabode T. Ladipo / Abdulafeez Akinloye / Adedeji Onayade / Oluseye O. Bolaji / Steve Rannard / Christian Happi / Andrew Owen / Adeniyi Olagunju

    Frontiers in Medicine, Vol

    2022  Volume 9

    Abstract: BackgroundThe nitazoxanide plus atazanavir/ritonavir for COVID-19 (NACOVID) trial investigated the efficacy and safety of repurposed nitazoxanide combined with atazanavir/ritonavir for COVID-19.MethodsThis is a pilot, randomized, open-label multicenter ... ...

    Abstract BackgroundThe nitazoxanide plus atazanavir/ritonavir for COVID-19 (NACOVID) trial investigated the efficacy and safety of repurposed nitazoxanide combined with atazanavir/ritonavir for COVID-19.MethodsThis is a pilot, randomized, open-label multicenter trial conducted in Nigeria. Mild to moderate COVID-19 patients were randomly assigned to receive standard of care (SoC) or SoC plus a 14-day course of nitazoxanide (1,000 mg b.i.d.) and atazanavir/ritonavir (300/100 mg od) and followed through day 28. Study endpoints included time to clinical improvement, SARS-CoV-2 viral load change, and time to complete symptom resolution. Safety and pharmacokinetics were also evaluated (ClinicalTrials.gov ID: NCT04459286).ResultsThere was no difference in time to clinical improvement between the SoC (n = 26) and SoC plus intervention arms (n = 31; Cox proportional hazards regression analysis adjusted hazard ratio, aHR = 0.898, 95% CI: 0.492–1.638, p = 0.725). No difference was observed in the pattern of saliva SARS-CoV-2 viral load changes from days 2–28 in the 35% of patients with detectable virus at baseline (20/57) (aHR = 0.948, 95% CI: 0.341–2.636, p = 0.919). There was no significant difference in time to complete symptom resolution (aHR = 0.535, 95% CI: 0.251–1.140, p = 0.105). Atazanavir/ritonavir increased tizoxanide plasma exposure by 68% and median trough plasma concentration was 1,546 ng/ml (95% CI: 797–2,557), above its putative EC90 in 54% of patients. Tizoxanide was undetectable in saliva.ConclusionNitazoxanide co-administered with atazanavir/ritonavir was safe but not better than standard of care in treating COVID-19. These findings should be interpreted in the context of incomplete enrollment (64%) and the limited number of patients with detectable SARS-CoV-2 in saliva at baseline in this trial.Clinical trial registration[https://clinicaltrials.gov/ct2/show/NCT04459286], identifier [NCT04459286].
    Keywords COVID-19 ; SARS-CoV-2 ; nitazoxanide (NTZ) ; atazanavir/ritonavir ; pharmacokinetics ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2022-09-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Survey data on employees' development and employees' satisfaction in oil and gas firms in Nigeria.

    Motilewa, Bolanle D / Bisi-Adeniyi, Christiana O / Fambegbe, Oluwaseyi A / Oyeyemi, Adeola I / Worlu, Rowland E K / Moses, Chinonye L

    Data in brief

    2018  Volume 19, Page(s) 1816–1821

    Abstract: Employees' development involves ensuring that employees are compensated fairly, are not exposed to dangerous or environmentally unhealthy working environment and are treated ethically in the workplace, especially in a technology intense industry as that ... ...

    Abstract Employees' development involves ensuring that employees are compensated fairly, are not exposed to dangerous or environmentally unhealthy working environment and are treated ethically in the workplace, especially in a technology intense industry as that of the oil and gas sector. Thus, this article presents data on the effect of employees' development on employees' satisfaction. The study employed a descriptive quantitative research design engaging survey method. The study population consists of 1748 employees from four top oil and gas firms quoted in the Nigerian stock exchange. A sample size of 350 employees was selected. Data was analysed using statistical Package for Social Sciences (SPSS). Regression analysis was employed as the statistical tool of analysis. The field data set is made widely accessible in this article.
    Language English
    Publishing date 2018-06-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2786545-9
    ISSN 2352-3409
    ISSN 2352-3409
    DOI 10.1016/j.dib.2018.06.066
    Database MEDical Literature Analysis and Retrieval System OnLINE

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