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  1. Article ; Online: Veterans Health Administration research in aging: Opportunities for high impact across the academic career.

    Vaughan, Camille P / Brown, Rebecca T / Hastings, S Nicole / Makris, Una E / Forman, Daniel E

    Journal of the American Geriatrics Society

    2023  Volume 71, Issue 9, Page(s) 3001–3004

    MeSH term(s) Humans ; Veterans Health ; Aging ; Career Choice
    Language English
    Publishing date 2023-04-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80363-7
    ISSN 1532-5415 ; 0002-8614
    ISSN (online) 1532-5415
    ISSN 0002-8614
    DOI 10.1111/jgs.18393
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.168: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Navigating a hyperracialized space: exploring the intersections of whiteness, social control, and mental health in st. louis county, missouri.

    Jones, Nicole E / Lewis, Kaleea / Brown, Alaysia M

    Ethnic and racial studies

    2022  Volume 46, Issue 5, Page(s) 966–986

    Abstract: Places marred by a legacy of racial violence have contemporary implications for racial and ethnic minorities. However, there is limited work examining how racial and ethnic minorities perceive and navigate these spaces and how they may affect their ... ...

    Abstract Places marred by a legacy of racial violence have contemporary implications for racial and ethnic minorities. However, there is limited work examining how racial and ethnic minorities perceive and navigate these spaces and how they may affect their health. We examine the daily lives of Black residents of St. Louis County, living in what we refer to as a
    Language English
    Publishing date 2022-07-13
    Publishing country England
    Document type Journal Article
    ISSN 0141-9870
    ISSN 0141-9870
    DOI 10.1080/01419870.2022.2085523
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: School Performance in Third Grade After a Full-Day vs Part-Day Preschool Program.

    Reynolds, Arthur J / Smerillo, Nicole E / Ou, Suh-Ruu / Loveman-Brown, Marley / Varshney, Nishank

    JAMA

    2023  Volume 330, Issue 22, Page(s) 2214–2215

    MeSH term(s) Academic Performance ; Educational Status ; Schools ; Time Factors ; Child, Preschool/education ; Humans ; Child
    Language English
    Publishing date 2023-11-20
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2023.20010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.88: Show issues Location:
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  4. Article ; Online: Aβ-induced synaptic impairments require CaMKII activity that is stimulated by indirect signaling events.

    Brown, Carolyn Nicole / Rumian, Nicole L / Tullis, Jonathan E / Coultrap, Steven J / Bayer, K Ulrich

    iScience

    2022  Volume 25, Issue 6, Page(s) 104368

    Abstract: Aβ bears homology to the CaMKII regulatory domain, and peptides derived from this domain can bind and disrupt the CaMKII holoenzyme, suggesting that Aβ could have a similar effect. Notably, Aβ impairs the synaptic CaMKII accumulation that is mediated by ... ...

    Abstract Aβ bears homology to the CaMKII regulatory domain, and peptides derived from this domain can bind and disrupt the CaMKII holoenzyme, suggesting that Aβ could have a similar effect. Notably, Aβ impairs the synaptic CaMKII accumulation that is mediated by GluN2B binding, which requires CaMKII assembly into holoenzymes. Furthermore, this Aβ-induced impairment is prevented by CaMKII inhibitors that should also inhibit the putative direct Aβ binding. However, our study did not find any evidence for direct effects of Aβ on CaMKII: Aβ did not directly disrupt CaMKII holoenzymes, GluN2B binding, T286 autophosphorylation, or kinase activity
    Language English
    Publishing date 2022-05-06
    Publishing country United States
    Document type Journal Article
    ISSN 2589-0042
    ISSN (online) 2589-0042
    DOI 10.1016/j.isci.2022.104368
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The Global Biodiversity Framework's ecosystem restoration target requires more clarity and careful legal interpretation.

    Bell-James, Justine / Foster, Rose / Shumway, Nicole / Lovelock, Catherine E / Villarreal-Rosas, Jaramar / Brown, Christopher J / Andradi-Brown, Dominic A / Saunders, Megan I / Waltham, Nathan J / Fitzsimons, James A

    Nature ecology & evolution

    2024  

    Language English
    Publishing date 2024-03-22
    Publishing country England
    Document type Letter
    ISSN 2397-334X
    ISSN (online) 2397-334X
    DOI 10.1038/s41559-024-02389-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The IMPOWR Network Divided or Single Exposure Study (DOSE) Protocol: A Randomized Controlled Comparison of Once Versus Split Dosing of Methadone for the Treatment of Comorbid Chronic Pain and Opioid Use Disorder.

    McKendrick, Greer / Davis, Will / Sklar, Michael / Brown, Nicole / Pattillo, Emma / Finan, Patrick H / Antoine, Denis / Walters, Vickie / Dunn, Kelly E

    Substance use & addiction journal

    2024  , Page(s) 29767342241239167

    Abstract: Background: The Divided or Single Exposure (DOSE) trial is a double-blind, placebo-controlled examination of once versus split dosing of methadone for comorbid pain and opioid use disorder (OUD) among persons receiving methadone for OUD treatment.: ... ...

    Abstract Background: The Divided or Single Exposure (DOSE) trial is a double-blind, placebo-controlled examination of once versus split dosing of methadone for comorbid pain and opioid use disorder (OUD) among persons receiving methadone for OUD treatment.
    Methods: This multisite trial consists of a 12-week active intervention phase and 6-month follow-up period. Persons receiving methadone who endorse clinically-significant chronic pain are randomized into once-daily dosing or split dosing that is managed remotely via an electronic pillbox. Clinical pain is assessed weekly and using ecological momentary assessments. Experimentally-evoked pain is assessed using a quantitative sensory testing battery. Additional outcomes related to OUD, including withdrawal and craving, are also collected.
    Results: The study hypothesizes that persons assigned to the split dosing condition will report lower pain and opioid withdrawal relative to persons assigned to the traditional once-daily dosing strategy.
    Conclusions: Split dosing is a relatively common technique in OUD treatments; therefore, if data support this hypothesis, there is high potential for implementation.
    Language English
    Publishing date 2024-03-25
    Publishing country United States
    Document type Journal Article
    ISSN 2976-7350
    ISSN (online) 2976-7350
    DOI 10.1177/29767342241239167
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Short-term CaMKII inhibition with tatCN19o does not erase pre-formed memory and is neuroprotective in non-rodents.

    Rumian, Nicole L / Brown, Carolyn Nicole / Hendry-Hofer, Tara B / Rossetti, Thomas / Orfila, James E / Tullis, Jonathan E / Dwoskin, Linda P / Buonarati, Olivia R / Lisman, John E / Quillinan, Nidia / Herson, Paco S / Bebarta, Vikhyat S / Bayer, K Ulrich

    bioRxiv : the preprint server for biology

    2023  

    Abstract: ... The ... ...

    Abstract The Ca
    Language English
    Publishing date 2023-01-23
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.01.23.523316
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A Systematic Review of the Consumer Emergency Care Satisfaction Scale (CECSS).

    Hoonakker, Peter L T / Carayon, Pascale / Brown, Roger L / Werner, Nicole E

    Journal of nursing care quality

    2022  Volume 37, Issue 4, Page(s) 349–355

    Abstract: Background: Patient experience is receiving increasing attention in the context of patient-centered care. However, there are relatively few instruments that measure patient experience that are valid and reliable.: Objective: In this study, we ... ...

    Abstract Background: Patient experience is receiving increasing attention in the context of patient-centered care. However, there are relatively few instruments that measure patient experience that are valid and reliable.
    Objective: In this study, we systematically review the literature on the Consumer Emergency Care Satisfaction Scale (CECSS) and examine its psychometric properties.
    Methods: We conducted a systematic literature search in the Cumulative Index to Nursing and Allied Health Literature, PubMed, PsycINFO, and Web of Science databases on articles that contain information on the CECSS. The review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
    Results: Our systematic literature search resulted in 28 articles in which the CECSS was used.
    Conclusions: Results of our literature review show that from a psychometric perspective, the CECSS is a valid and reliable instrument. However, the results of our study also show that the CECSS has several weaknesses. We have made recommendations to improve the CECSS.
    MeSH term(s) Emergency Medical Services ; Humans ; Personal Satisfaction ; Psychometrics
    Language English
    Publishing date 2022-07-08
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 1089089-0
    ISSN 1550-5065 ; 1057-3631
    ISSN (online) 1550-5065
    ISSN 1057-3631
    DOI 10.1097/NCQ.0000000000000636
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3102: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Measuring older adults' wellbeing when transitioning into assisted living facilities: a confirmatory factor analysis of the Mueller assessment of transition (MAT).

    Mueller, Kaitlin E / Van Puymbroeck, Marieke / Brown, Christy / Crowe, Brandi M / Davis, Nicole

    Aging & mental health

    2023  , Page(s) 1–7

    Abstract: Objectives: Older adults' wellbeing during the transition into an assisted living facility (ALF) is not well understood and may influence their wellbeing. The Mueller Assessment of Transition (MAT) was created to measure the impact of transition on ... ...

    Abstract Objectives: Older adults' wellbeing during the transition into an assisted living facility (ALF) is not well understood and may influence their wellbeing. The Mueller Assessment of Transition (MAT) was created to measure the impact of transition on older adults' wellbeing. Early developmental testing of the MAT revealed a hypothesized model with two constructs (adjustment strategies and constraints to wellbeing). Therefore, the purpose of this study was to confirm the factor structure of the MAT with a representative sample of older adults transitioning into ALFs.
    Methods: In a nationwide sample, 108 older adult participants completed the MAT to measure wellbeing when relocating into ALFs. Confirmatory factor analysis (CFA) assessed the structural validity of the MAT. Internal consistency was evaluated, and chi-square tests of association for regional differences in MAT scores were also conducted.
    Results: The CFA produced strong fit indices to confirm the hypothesized 2-factor (constraints to wellbeing and adjustment strategies) model of the MAT. Cronbach's alpha for the internal consistency was 0.784 and chi-square test indicated no significant regional differences.
    Conclusion: The MAT was established as a valid and reliable standardized assessment. Implications for using the MAT as a tool to measure older adults' wellbeing and future research are discussed.
    Language English
    Publishing date 2023-12-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 1474804-6
    ISSN 1364-6915 ; 1360-7863
    ISSN (online) 1364-6915
    ISSN 1360-7863
    DOI 10.1080/13607863.2023.2293054
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5081: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  10. Article ; Online: LTP induction by structural rather than enzymatic functions of CaMKII.

    Tullis, Jonathan E / Larsen, Matthew E / Rumian, Nicole L / Freund, Ronald K / Boxer, Emma E / Brown, Carolyn Nicole / Coultrap, Steven J / Schulman, Howard / Aoto, Jason / Dell'Acqua, Mark L / Bayer, K Ulrich

    Nature

    2023  Volume 621, Issue 7977, Page(s) 146–153

    Abstract: Learning and memory are thought to require hippocampal long-term potentiation (LTP), and one of the few central dogmas of molecular neuroscience that has stood undisputed for more than three decades is that LTP induction requires enzymatic activity of ... ...

    Abstract Learning and memory are thought to require hippocampal long-term potentiation (LTP), and one of the few central dogmas of molecular neuroscience that has stood undisputed for more than three decades is that LTP induction requires enzymatic activity of the Ca
    MeSH term(s) Calcium-Calmodulin-Dependent Protein Kinase Type 2/antagonists & inhibitors ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/chemistry ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism ; Glutamic Acid/metabolism ; Hippocampus/physiology ; Learning/physiology ; Long-Term Potentiation/physiology ; Optogenetics ; Phosphorylation ; Protein Binding
    Chemical Substances Calcium-Calmodulin-Dependent Protein Kinase Type 2 (EC 2.7.11.17) ; Glutamic Acid (3KX376GY7L) ; NR2B NMDA receptor
    Language English
    Publishing date 2023-08-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/s41586-023-06465-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 26: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 9: Show issues
    Zs.MO 244: Show issues

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