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  1. Article ; Online: Transient Increase of Pre-existing Anti-IFN-α2 Antibodies Induced by SARS-CoV-2 Infection.

    Steels, Sophie / Van Elslande, Jan / De Munter, Paul / Bossuyt, Xavier

    Journal of clinical immunology

    2022  Volume 42, Issue 4, Page(s) 742–745

    MeSH term(s) Antibodies, Viral ; COVID-19 ; Humans ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus
    Chemical Substances Antibodies, Viral ; Spike Glycoprotein, Coronavirus ; spike protein, SARS-CoV-2
    Language English
    Publishing date 2022-03-17
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 779361-3
    ISSN 1573-2592 ; 0271-9142
    ISSN (online) 1573-2592
    ISSN 0271-9142
    DOI 10.1007/s10875-022-01235-3
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1640: Show issues Location:
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  2. Article ; Online: Estimated Half-Life of SARS-CoV-2 Anti-Spike Antibodies More Than Double the Half-Life of Anti-nucleocapsid Antibodies in Healthcare Workers.

    Van Elslande, Jan / Gruwier, Lien / Godderis, Lode / Vermeersch, Pieter

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2021  Volume 73, Issue 12, Page(s) 2366–2368

    MeSH term(s) Antibodies, Viral ; COVID-19 ; Half-Life ; Health Personnel ; Humans ; SARS-CoV-2
    Chemical Substances Antibodies, Viral
    Language English
    Publishing date 2021-03-10
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciab219
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    Zs.A 1505: Show issues Location:
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    Zs.MO 480: Show issues

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  3. Article: Three Cases of Atypical Pneumonia with

    Missault, Sophie / De Meyst, Anne / Van Elslande, Jan / Van den Abeele, Anne-Marie / Steen, Elke / Van Acker, Jos / Vanrompay, Daisy

    Pathogens (Basel, Switzerland)

    2022  Volume 12, Issue 1

    Abstract: Chlamydia ... ...

    Abstract Chlamydia psittaci
    Language English
    Publishing date 2022-12-31
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens12010065
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  4. Article ; Online: IgG anti-spike antibody levels in healthcare workers with and without prior COVID-19 up to 3 months after BNT162b2 vaccination.

    Van Elslande, Jan / Weemaes, Matthias / Godderis, Lode / Van Pottelbergh, Gijs / Bossuyt, Xavier / Vermeersch, Pieter

    Diagnostic microbiology and infectious disease

    2022  Volume 102, Issue 4, Page(s) 115638

    Abstract: We report IgG anti-spike levels up to 3 months after vaccination with 2 doses of BNT162b2 mRNA vaccine in healthcare workers (HCW). The antibody response was significantly stronger in previously infected vaccinated HCW compared to uninfected HCW, and ... ...

    Abstract We report IgG anti-spike levels up to 3 months after vaccination with 2 doses of BNT162b2 mRNA vaccine in healthcare workers (HCW). The antibody response was significantly stronger in previously infected vaccinated HCW compared to uninfected HCW, and stronger after vaccination compared to (mostly) mild natural infection.
    MeSH term(s) Antibodies, Viral ; BNT162 Vaccine ; COVID-19/prevention & control ; COVID-19 Vaccines ; Health Personnel ; Humans ; Immunoglobulin G ; SARS-CoV-2 ; Vaccination ; Vaccines, Synthetic ; mRNA Vaccines
    Chemical Substances Antibodies, Viral ; COVID-19 Vaccines ; Immunoglobulin G ; Vaccines, Synthetic ; mRNA Vaccines ; BNT162 Vaccine (N38TVC63NU)
    Language English
    Publishing date 2022-01-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604920-5
    ISSN 1879-0070 ; 0732-8893
    ISSN (online) 1879-0070
    ISSN 0732-8893
    DOI 10.1016/j.diagmicrobio.2022.115638
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1845: Show issues Location:
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  5. Article ; Online: Immunoassays for anti-SARS-CoV-2 antibodies: recent insights.

    Van Elslande, Jan / André, Emmanuel / Van Ranst, Marc / Lagrou, Katrien / Vermeersch, Pieter

    The Lancet. Infectious diseases

    2020  Volume 21, Issue 5, Page(s) e120

    MeSH term(s) Antibodies, Viral ; Benchmarking ; COVID-19 ; Humans ; Immunoassay ; SARS-CoV-2
    Chemical Substances Antibodies, Viral
    Keywords covid19
    Language English
    Publishing date 2020-10-30
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(20)30846-X
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    Zs.A 5743: Show issues Location:
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  6. Article ; Online: Corrigendum: IgG anti-spike antibodies and surrogate neutralizing antibody levels decline faster 3 to 10 months after BNT162b2 vaccination than after SARS-CoV-2 infection in healthcare workers.

    Decru, Bram / Van Elslande, Jan / Steels, Sophie / Van Pottelbergh, Gijs / Godderis, Lode / Van Holm, Bram / Bossuyt, Xavier / Van Weyenbergh, Johan / Maes, Piet / Vermeersch, Pieter

    Frontiers in immunology

    2022  Volume 13, Page(s) 1098285

    Abstract: This corrects the article DOI: 10.3389/fimmu.2022.909910.]. ...

    Abstract [This corrects the article DOI: 10.3389/fimmu.2022.909910.].
    Language English
    Publishing date 2022-11-25
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2022.1098285
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  8. Article ; Online: A case of severe pseudohyperkalaemia due to muscle contraction.

    Van Elslande, Jan / Dominicus, Toon / Toelen, Jaan / Frans, Glynis / Vermeersch, Pieter

    Biochemia medica

    2020  Volume 30, Issue 2, Page(s) 21004

    Abstract: Introduction: Severe hyperkalaemia is a serious medical condition requiring immediate medical attention. Before medical treatment is started, pseudohyperkalaemia has to be ruled out.: Case description: A 10-month old infant presented to the emergency ...

    Abstract Introduction: Severe hyperkalaemia is a serious medical condition requiring immediate medical attention. Before medical treatment is started, pseudohyperkalaemia has to be ruled out.
    Case description: A 10-month old infant presented to the emergency department with fever and coughing since 1 week. Routine venous blood testing revealed a severe hyperkalaemia of 6.9 mmol/L without any indication of haemolysis. Reanalysis of the plasma sample confirmed the hyperkalaemia (7.1 mmol/L). Based on these results, the clinical pathologist suggested to perform a venous blood gas analysis and electrocardiogram (ECG) which revealed a normal potassium of 3.7 mmol/L and normal ECG, ruling out a potentially life-treating hyperkalaemia. The child was diagnosed with pneumonia. The paediatrician had difficulty to perform the first venous blood collection due to excessive movement of the infant during venipuncture. The muscle contractions of the child in combination with venous stasis most probably led to a local increase of potassium in the sampled limbs. The second sample collected under optimal preanalytical circumstances had a normal potassium. Since muscle contraction typically does not cause severe hyperkalaemia, other causes of pseudohyperkalaemia were excluded. K
    Conclusion: This case suggests that intense muscle contraction and venous stasis can cause severe pseudohyperkalemia without hemolysis. Once true hyperkalemia has been ruled out, a laboratory work-up can help identify the cause of pseudohyperkalaemia.
    MeSH term(s) Blood Chemical Analysis ; Blood Gas Analysis ; Cough ; Diagnosis, Differential ; Edetic Acid ; Fever ; Humans ; Hyperkalemia/diagnosis ; Hyperkalemia/etiology ; Infant ; Leukocytosis/diagnosis ; Male ; Muscle Contraction ; Muscle, Skeletal/physiopathology ; Pneumonia/diagnosis ; Potassium/blood ; Reproducibility of Results ; Thrombocytosis/diagnosis
    Chemical Substances Edetic Acid (9G34HU7RV0) ; Potassium (RWP5GA015D)
    Language English
    Publishing date 2020-04-13
    Publishing country Croatia
    Document type Case Reports
    ZDB-ID 1208725-7
    ISSN 1846-7482 ; 1330-0962
    ISSN (online) 1846-7482
    ISSN 1330-0962
    DOI 10.11613/BM.2020.021004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4273: Show issues Location:
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  9. Article ; Online: Immunoassays for anti-SARS-CoV-2 antibodies

    Van Elslande, Jan / André, Emmanuel / Van Ranst, Marc / Lagrou, Katrien / Vermeersch, Pieter

    The Lancet Infectious Diseases ; ISSN 1473-3099

    recent insights

    2020  

    Keywords Infectious Diseases ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/s1473-3099(20)30846-x
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Complementarity determining regions in SARS-CoV-2 hybrid immunity.

    Frans, Glynis / Dillaerts, Doreen / Dehaemers, Tom / Van Elslande, Jan / De Leeuw, Jonas / Boon, Lise / Maes, Wim / Callewaert, Nico / Calcoen, Bas / Ancheva, Lina / Cockx, Maaike / Geukens, Nick / Arat, Kusay / Derua, Rita / Vermeersch, Pieter / Carpentier, Sebastien Christian / Bossuyt, Xavier

    Frontiers in immunology

    2023  Volume 14, Page(s) 1050037

    Abstract: Pre-vaccination SARS-CoV-2 infection can boost protection elicited by COVID-19 vaccination and post-vaccination breakthrough SARS-CoV-2 infection can boost existing immunity conferred by COVID-19 vaccination. Such 'hybrid immunity' is effective against ... ...

    Abstract Pre-vaccination SARS-CoV-2 infection can boost protection elicited by COVID-19 vaccination and post-vaccination breakthrough SARS-CoV-2 infection can boost existing immunity conferred by COVID-19 vaccination. Such 'hybrid immunity' is effective against SARS-CoV-2 variants. In order to understand 'hybrid immunity' at the molecular level we studied the complementarity determining regions (CDR) of anti-RBD (receptor binding domain) antibodies isolated from individuals with 'hybrid immunity' as well as from 'naive' (not SARS-CoV-2 infected) vaccinated individuals. CDR analysis was done by liquid chromatography/mass spectrometry-mass spectrometry. Principal component analysis and partial least square differential analysis showed that COVID-19 vaccinated people share CDR profiles and that pre-vaccination SARS-CoV-2 infection or breakthrough infection further shape the CDR profile, with a CDR profile in hybrid immunity that clustered away from the CDR profile in vaccinated people without infection. Thus, our results show a CDR profile in hybrid immunity that is distinct from the vaccination-induced CDR profile.
    MeSH term(s) Humans ; SARS-CoV-2 ; COVID-19/prevention & control ; Complementarity Determining Regions/genetics ; COVID-19 Vaccines
    Chemical Substances Complementarity Determining Regions ; COVID-19 Vaccines
    Language English
    Publishing date 2023-02-21
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1050037
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