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  1. Article ; Online: Clinical Characteristics of Lichen Amyloidosis Associated with Atopic Dermatitis: A Single Center, Retrospective Study.

    Oh, Seung-Min / Ahn, Hye-Jin / Shin, Min Kyung

    Annals of dermatology

    2023  Volume 35, Issue 6, Page(s) 432–438

    Abstract: Background: Lichen amyloidosis is a chronic pruritic skin disorder associated with atopic dermatitis, however, the pathogenetic link between these two conditions remains to be elucidated. Only limited research has been performed on patients diagnosed ... ...

    Abstract Background: Lichen amyloidosis is a chronic pruritic skin disorder associated with atopic dermatitis, however, the pathogenetic link between these two conditions remains to be elucidated. Only limited research has been performed on patients diagnosed with both pruritic dermatological conditions.
    Objective: This study aimed to analyze the clinical features of lichen amyloidosis associated with atopic dermatitis.
    Methods: We conducted a matched case-control study of incident lichen amyloidosis with atopic dermatitis between March 2020 and February 2022. Among the 2,481 patients with atopic dermatitis, 20 patients diagnosed with lichen amyloidosis and atopic dermatitis were included as case patients, and 20 patients diagnosed with atopic dermatitis were enrolled as controls. The controls were matched to cases (1:1) by age and sex. We retrospectively reviewed the medical records of the patients.
    Results: The prevalence of lichen amyloidosis associated with atopic dermatitis was approximately 0.8%, with a male:female sex ratio of 2.33:1. The recorded onset of lichen amyloidosis associated with atopic dermatitis was more common in adult patients, with moderate-to-severe atopic dermatitis. Lichen amyloidosis lesions in patients with atopic dermatitis were most commonly found on the extremities, sparing the head and neck region. The presence of lichen amyloidosis had no significant impact on severity of atopic dermatitis.
    Conclusion: In patients with lichen amyloidosis associated with atopic dermatitis, the clinical manifestations of lesions are similar to those of conventional lichen amyloidosis lesions in terms of morphology and regional distribution. Further research is required to elucidate the link between the pathogenesis of these two pruritic dermatological conditions.
    Language English
    Publishing date 2023-12-09
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 1012662-4
    ISSN 2005-3894 ; 1013-9087
    ISSN (online) 2005-3894
    ISSN 1013-9087
    DOI 10.5021/ad.23.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2800: Show issues Location:
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  2. Article: Carbonation of a Synthetic CAF Compound by CO

    Lee, Woong-Geol / Kang, Seung-Min / Song, Myong-Shin

    Materials (Basel, Switzerland)

    2023  Volume 16, Issue 23

    Abstract: In the field of construction materials, the development of fundamental technologies to reduce energy consumption and ... ...

    Abstract In the field of construction materials, the development of fundamental technologies to reduce energy consumption and CO
    Language English
    Publishing date 2023-11-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma16237344
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The Characteristics of Self-Hydration and Carbonation Reaction of Coal Ash from Circulating Fluidized-Bed Boiler by Absorption of CO

    Lee, Woong-Geol / Song, Myong-Shin / Kang, Seung-Min

    Materials (Basel, Switzerland)

    2023  Volume 16, Issue 15

    Abstract: The by-products of the circulating fluidized-bed boiler combustion (CFBC) of coal exhibit self-hardening properties due to the calcium silicates generated by the reaction between ... ...

    Abstract The by-products of the circulating fluidized-bed boiler combustion (CFBC) of coal exhibit self-hardening properties due to the calcium silicates generated by the reaction between SiO
    Language English
    Publishing date 2023-08-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma16155498
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  4. Article ; Online: A case of rapidly aggravated cutaneous facial infection of Trichosporon asahii in an immunocompetent patient.

    Ahn, Hye-Jin / Oh, Seung-Min / Shin, Min Kyung

    The Australasian journal of dermatology

    2022  Volume 64, Issue 1, Page(s) e81–e83

    MeSH term(s) Humans ; Basidiomycota ; Antifungal Agents/therapeutic use ; Skin Diseases, Infectious/drug therapy ; Cellulitis/drug therapy
    Chemical Substances Antifungal Agents
    Language English
    Publishing date 2022-11-10
    Publishing country Australia
    Document type Case Reports ; Letter
    ZDB-ID 138052-7
    ISSN 1440-0960 ; 0004-8380
    ISSN (online) 1440-0960
    ISSN 0004-8380
    DOI 10.1111/ajd.13949
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    Zs.A 236: Show issues Location:
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  5. Article ; Online: Author Correction: Age-dependent loss of Crls1 causes myopathy and skeletal muscle regeneration failure.

    Yoo, Youngbum / Yeon, MyeongHoon / Kim, Won-Kyung / Shin, Hyeon-Bin / Lee, Seung-Min / Yoon, Mee-Sup / Ro, Hyunju / Seo, Young-Kyo

    Experimental & molecular medicine

    2024  Volume 56, Issue 4, Page(s) 1031

    Language English
    Publishing date 2024-04-25
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 1328915-9
    ISSN 2092-6413 ; 1226-3613 ; 0378-8512
    ISSN (online) 2092-6413
    ISSN 1226-3613 ; 0378-8512
    DOI 10.1038/s12276-024-01238-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Droplet digital PCR method for the absolute quantitative detection and monitoring of Lacticaseibacillus casei.

    Kim, Eiseul / Yang, Seung-Min / Choi, Changs Hun / Shin, Min-Ki / Kim, Hae-Yeong

    Food microbiology

    2023  Volume 113, Page(s) 104265

    Abstract: Droplet digital polymerase chain reaction (ddPCR) is an emerging molecular detection assay that provides an absolute quantification of targets. Despite its emerging applications in the detection of food microorganisms, there are limited reports of its ... ...

    Abstract Droplet digital polymerase chain reaction (ddPCR) is an emerging molecular detection assay that provides an absolute quantification of targets. Despite its emerging applications in the detection of food microorganisms, there are limited reports of its use for the monitoring of microorganisms utilized as starters in the dairy industry. This study investigated the applicability of ddPCR as a detection platform for Lacticaseibacillus casei, a probiotic found in fermented foods and exerts beneficial effects on human health. In addition, this study compared the performance of ddPCR with that of real-time PCR. The ddPCR targeting the haloacid dehalogenase-like hydrolase (LBCZ_1793) exhibited high specificity against 102 nontarget bacteria, including Lacticaseibacillus species that is very closely related to L. casei. The ddPCR exhibited high linearity and efficiency within the quantitation range (10
    MeSH term(s) Humans ; Lacticaseibacillus ; Lacticaseibacillus casei/genetics ; Real-Time Polymerase Chain Reaction/methods ; Food
    Language English
    Publishing date 2023-03-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 50892-5
    ISSN 1095-9998 ; 0740-0020
    ISSN (online) 1095-9998
    ISSN 0740-0020
    DOI 10.1016/j.fm.2023.104265
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4667: Show issues Location:
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  7. Article: Kaposi's Sarcoma-Associated Herpesvirus and Host Interaction by the Complement System.

    Yoo, Seung-Min / Lee, Myung-Shin

    Pathogens (Basel, Switzerland)

    2020  Volume 9, Issue 4

    Abstract: Kaposi's sarcoma-associated herpesvirus (KSHV) modulates the immune response to allow the virus to establish persistent infection in the host and facilitate the development of KSHV-associated cancer. The complement system has a central role in the ... ...

    Abstract Kaposi's sarcoma-associated herpesvirus (KSHV) modulates the immune response to allow the virus to establish persistent infection in the host and facilitate the development of KSHV-associated cancer. The complement system has a central role in the defense against pathogens. Hence, KSHV has adopted an evasion strategy for complement attack using the viral protein encoded by KSHV open reading frame 4. However, despite this defense mechanism, the complement system appears to become activated in KSHV-infected cells as well as in the region surrounding Kaposi's sarcoma tumors. Given that the complement system can affect cell fate as well as the inflammatory microenvironment, complement activation is likely associated with KSHV pathogenesis. A better understanding of the interplay between KSHV and the complement system may, therefore, translate into the development of novel therapeutic interventions for KSHV-associated tumors. In this review, the mechanisms and functions of complement activation in KSHV-infected cells are discussed.
    Language English
    Publishing date 2020-04-03
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens9040260
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  8. Article ; Online: CO 2 Diffusion and Carbonation in OPC/γ-2CaO·SiO 2 Composite

    Seung-Min Kang / Kwang-Kyun Moon / Woong-Geol Lee / Myong-Shin Song

    Applied Sciences, Vol 13, Iss 4529, p

    2023  Volume 4529

    Abstract: Gamma dicalcium silicate (γ-2CaO∙SiO 2 , abbreviated as γ-C 2 S) is considered a potential candidate as a construction material owing to its high carbonation reactivity and consequent CO 2 absorption. This study investigates the diffusion of CO 2 , a ... ...

    Abstract Gamma dicalcium silicate (γ-2CaO∙SiO 2 , abbreviated as γ-C 2 S) is considered a potential candidate as a construction material owing to its high carbonation reactivity and consequent CO 2 absorption. This study investigates the diffusion of CO 2 , a physical process, into hardened cement paste and the resulting carbonation, a chemical process. CO 2 diffuses from a region of high concentration to one of a lower concentration, which is the inner core of the hardened cement. This study aimed to examine whether the diffusion of CO 2 into the ordinary Portland cement (OPC)/γ-C 2 S composite paste followed the conventional laws of diffusion. We also studied the diffusion of CaCO 3 to determine if carbonation products were formed in the pores and examined the capture of CO 2 . The paste specimens were prepared and subjected to CO 2 in the carbonation chambers for varying periods. The results showed that the CaCO 3 deposited in the pores affected the rate of diffusion of CO 2 in the mortars and pastes, resulting in the densification of such bodies and a decreased rate of diffusion, leading to the shutdown of diffusion. The diffusion of CO 2 in hardened cement pastes made from OPC and γ-C 2 S follows Fick’s second law, wherein there is a change in the concentration of CO 2 diffusing at a particular distance with time.
    Keywords CO 2 ; carbonation ; diffusion ; γ-C 2 S ; Fick’s laws ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 290
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Age-dependent loss of Crls1 causes myopathy and skeletal muscle regeneration failure.

    Yoo, Youngbum / Yeon, MyeongHoon / Kim, Won-Kyung / Shin, Hyeon-Bin / Lee, Seung-Min / Yoon, Mee-Sup / Ro, Hyunju / Seo, Young-Kyo

    Experimental & molecular medicine

    2024  Volume 56, Issue 4, Page(s) 922–934

    Abstract: Skeletal muscle aging results in the gradual suppression of myogenesis, leading to muscle mass loss. However, the specific role of cardiolipin in myogenesis has not been determined. This study investigated the crucial role of mitochondrial cardiolipin ... ...

    Abstract Skeletal muscle aging results in the gradual suppression of myogenesis, leading to muscle mass loss. However, the specific role of cardiolipin in myogenesis has not been determined. This study investigated the crucial role of mitochondrial cardiolipin and cardiolipin synthase 1 (Crls1) in age-related muscle deterioration and myogenesis. Our findings demonstrated that cardiolipin and Crls1 are downregulated in aged skeletal muscle. Moreover, the knockdown of Crls1 in myoblasts reduced mitochondrial mass, activity, and OXPHOS complex IV expression and disrupted the structure of the mitochondrial cristae. AAV9-shCrls1-mediated downregulation of Crls1 impaired muscle regeneration in a mouse model of cardiotoxin (CTX)-induced muscle damage, whereas AAV9-mCrls1-mediated Crls1 overexpression improved regeneration. Overall, our results highlight that the age-dependent decrease in CRLS1 expression contributes to muscle loss by diminishing mitochondrial quality in skeletal muscle myoblasts. Hence, modulating CRLS1 expression is a promising therapeutic strategy for mitigating muscle deterioration associated with aging, suggesting potential avenues for developing interventions to improve overall muscle health and quality of life in elderly individuals.
    MeSH term(s) Animals ; Muscle, Skeletal/metabolism ; Muscle, Skeletal/pathology ; Mice ; Regeneration ; Muscular Diseases/metabolism ; Muscular Diseases/etiology ; Muscular Diseases/pathology ; Muscular Diseases/genetics ; Aging/metabolism ; Muscle Development ; Mitochondria/metabolism ; Disease Models, Animal ; Humans ; Cardiolipins/metabolism ; Mitochondrial Proteins/metabolism ; Mitochondrial Proteins/genetics ; Male ; Myoblasts/metabolism
    Chemical Substances Cardiolipins ; Mitochondrial Proteins
    Language English
    Publishing date 2024-04-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1328915-9
    ISSN 2092-6413 ; 1226-3613 ; 0378-8512
    ISSN (online) 2092-6413
    ISSN 1226-3613 ; 0378-8512
    DOI 10.1038/s12276-024-01199-x
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  10. Article ; Online: Fatty acid oxidation facilitates DNA double-strand break repair by promoting PARP1 acetylation.

    Yang, Seungyeon / Hwang, Sunsook / Kim, Byungjoo / Shin, Seungmin / Kim, Minjoong / Jeong, Seung Min

    Cell death & disease

    2023  Volume 14, Issue 7, Page(s) 435

    Abstract: DNA repair is a tightly coordinated stress response to DNA damage, which is critical for preserving genome integrity. Accruing evidence suggests that metabolic pathways have been correlated with cellular response to DNA damage. Here, we show that fatty ... ...

    Abstract DNA repair is a tightly coordinated stress response to DNA damage, which is critical for preserving genome integrity. Accruing evidence suggests that metabolic pathways have been correlated with cellular response to DNA damage. Here, we show that fatty acid oxidation (FAO) is a crucial regulator of DNA double-strand break repair, particularly homologous recombination repair. Mechanistically, FAO contributes to DNA repair by activating poly(ADP-ribose) polymerase 1 (PARP1), an enzyme that detects DNA breaks and promotes DNA repair pathway. Upon DNA damage, FAO facilitates PARP1 acetylation by providing acetyl-CoA, which is required for proper PARP1 activity. Indeed, cells reconstituted with PARP1 acetylation mutants display impaired DNA repair and enhanced sensitivity to DNA damage. Consequently, FAO inhibition reduces PARP1 activity, leading to increased genomic instability and decreased cell viability upon DNA damage. Finally, our data indicate that FAO serves as an important participant of cellular response to DNA damage, supporting DNA repair and genome stability.
    MeSH term(s) Humans ; Acetylation ; DNA Repair ; DNA/metabolism ; Poly (ADP-Ribose) Polymerase-1/metabolism ; DNA Breaks, Double-Stranded ; DNA Damage ; Fatty Acids
    Chemical Substances DNA (9007-49-2) ; Poly (ADP-Ribose) Polymerase-1 (EC 2.4.2.30) ; Fatty Acids ; PARP1 protein, human (EC 2.4.2.30)
    Language English
    Publishing date 2023-07-15
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2541626-1
    ISSN 2041-4889 ; 2041-4889
    ISSN (online) 2041-4889
    ISSN 2041-4889
    DOI 10.1038/s41419-023-05968-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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