LIVIVO - Search results -

Search results

Result 1 - 10 of total 16

Search options

Article: Botanical, chemical and pharmacological properties of artocarpus lakoocha (monkey fruit): A review

Gupta, Arun Kumar / Pathak, Urbi / Medhi, Manisha / Mastinu, Andrea / Sikarwar, Mukesh S / Mishra, Poonam

Agricultural reviews. 2020 Dec., v. 41, no. 4

2020

Abstract: Artocarpus are members of the Moraceae family who are believed to be a large family comprises of nearly 60 genera and about 1400 species. The most important genus of the Moraceae family is Ficus, Morus and Artocarpus. The extract and bioactive compounds ... ...

Abstract	Artocarpus are members of the Moraceae family who are believed to be a large family comprises of nearly 60 genera and about 1400 species. The most important genus of the Moraceae family is Ficus, Morus and Artocarpus. The extract and bioactive compounds from bark, leaves, seeds and pericarp of monkey fruit have shown to possess exceptional phytochemical, nutritional and valuable pharmacological properties. This fruit is capable of offering numerous inhibitory factors such as antibacterial, antitubercular, antiviral, antifungal, antiplatelet, antiarthritic, tyrosinase inhibitory and cytotoxicity. This review devotes the complete overview of pharmacological and bioactive components exclusively found in the monkey fruit and its parts. However, fruit exhibits appreciable properties, but they are still unknown as well as underutilized. The remarkable properties of plants and the modern approaches are needed for the treatment of chronic diseases, the development of drugs and functional food products, or for the improvement of properties existed ones.
Keywords	Artocarpus lacucha ; Ficus ; bark ; cytotoxicity ; functional foods ; monkeys ; pericarp ; phytochemicals
Language	English
Dates of publication	2020-12
Size	p. 305-316.
Publishing place	Agricultural Research Communication Centre
Document type	Article
Note	NAL-AP-2-clean
ISSN	0976-0741
DOI	10.18805/ag.R-1989
Database	NAL-Catalogue (AGRICOLA)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Antihyperlipidemic activity of Salacia chinensis root extracts in triton-induced and atherogenic diet-induced hyperlipidemic rats.

Sikarwar, Mukesh S / Patil, M B

Indian journal of pharmacology

2012 Volume 44, Issue 1, Page(s) 88–92

Abstract: ... expressed as mean± S.E. and data was analyzed by using one way analysis of variance test (ANOVA) followed ...

Abstract	Objectives: The aim of this study has been to investigate the possible antihyperlipidemic effect of Salacia chinensis root extract in triton (400mg/kg b.w.)-induced and atherogenic diet-induced hyperlipidemic rats. Materials and methods: Petroleum ether (60-80°C), chloroform, ethanol and aqueous extracts of Salacia chinensis roots were evaluated for antihyperlipidemic activity in triton- and atherogenic diet-induced hyperlipidemic rats. A comparison was also made between the action of Salacia chinensis root extract and a known antihyperlipidemic drug simvastatin (10 mg/kg body wt.). The results of the study were expressed as mean± S.E. and data was analyzed by using one way analysis of variance test (ANOVA) followed by Dunnett's t-test for multiple comparisons. Values with P < 0.05 were considered as significant. Results: Oral administration of 500 mg/kg body wt. of the chloroform extract and alcoholic extract of Salacia chinensis root exhibited a significant reduction (P<0.01) in serum lipid parameters like total cholesterol, triglycerides, low density lipoprotein (LDL), very low density lipopreotein (VLDL) and increase in high density lipoprotein (HDL) in hyperlipidemic rats of both models as compared to hyperlipidemic control statistically. These extracts were found to possess better antihyperlipidemic potential as compared to pet ether and aqueous extract. Conclusions: Our results demonstrated that chloroform and alcoholic extract of Salacia chinensis roots possessed significant antihyperlipidemic activity and hence it could be a potential herbal medicine as adjuvant with existing therapy for the treatment of hyperlipidemia.
Language	English
Publishing date	2012-02-16
Publishing country	India
Document type	Journal Article
ZDB-ID	605829-2
ISSN	1998-3751 ; 0253-7613
ISSN (online)	1998-3751
ISSN	0253-7613
DOI	10.4103/0253-7613.91875
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1983: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 311: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Antidiabetic activity of Crateva nurvala stem bark extracts in alloxan-induced diabetic rats.

Sikarwar, Mukesh S / Patil, M B

Journal of pharmacy & bioallied sciences

2011 Volume 2, Issue 1, Page(s) 18–21

Abstract: Objectives: The aim of this study was to investigate the antidiabetic activity of Crateva nurvala stem bark (family: Capparidaceae) extracts in alloxan-induced diabetic albino rats. A comparison was made between the action of different extracts of C. ... ...

Abstract	Objectives: The aim of this study was to investigate the antidiabetic activity of Crateva nurvala stem bark (family: Capparidaceae) extracts in alloxan-induced diabetic albino rats. A comparison was made between the action of different extracts of C. nurvala and a known antidiabetic drug glibenclamide (600 μg/kg b. wt.). An oral glucose tolerance test (OGTT) was also performed in diabetic rats. Materials and methods: The petroleum ether, chloroform, alcohol, and aqueous extracts of C. nurvala stem bark were obtained by simple maceration method and were subjected to standardization by following pharmacognostical and phytochemical screening methods. Dose selection was made on the basis of acute oral toxicity study (50-5000 mg/kg b. wt.) as per Organization for Economic Co-operation and Development (OECD) guidelines. Results and conclusions: C. nurvala petroleum ether extract (CNPEE) and ethanolic extract (CNEE) showed significant (P< 0.001) antidiabetic activities. In alloxan-induced model, blood glucose level of these extracts on seventh day of study were CNPEE (126.33±13.703 mg/dl) and CNEE (126.66±13.012 mg/dl) when compared with diabetic control (413.50±4.752 mg/dl) and chloroform extract (320.83±13.516 mg/dl). In OGGT model (glucose loaded rats), CNPEE showed a glucose level of 178.83±3.070 mg/dl after 30 min and 131.66±2.486 mg/dl after 90 min, whereas CNEE showed 173.66±4.224 mg/dl after 30 min and 115.50±3.394 mg/dl after 90 min. These extracts also prevented body weight loss in diabetic rats. The drug has the potential to act as an antidiabetic drug.
Language	English
Publishing date	2011-07-19
Publishing country	India
Document type	Journal Article
ZDB-ID	2573569-X
ISSN	0975-7406 ; 0975-7406
ISSN (online)	0975-7406
ISSN	0975-7406
DOI	10.4103/0975-7406.62700
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Antidiabetic activity of Pongamia pinnata leaf extracts in alloxan-induced diabetic rats.

Sikarwar, Mukesh S / Patil, M B

International journal of Ayurveda research

2011 Volume 1, Issue 4, Page(s) 199–204

Abstract: The antidiabetic activity of Pongamia pinnata ( Family: Leguminosae) leaf extracts was investigated in alloxan-induced diabetic albino rats. A comparison was made between the action of different extracts of P. pinnata and a known antidiabetic drug ... ...

Abstract	The antidiabetic activity of Pongamia pinnata ( Family: Leguminosae) leaf extracts was investigated in alloxan-induced diabetic albino rats. A comparison was made between the action of different extracts of P. pinnata and a known antidiabetic drug glibenclamide (600 μg/kg b. wt.). An oral glucose tolerance test (OGTT) was also performed in experimental diabetic rats. The petroleum ether, chloroform, alcohol and aqueous extracts of P. pinnata were obtained by simple maceration method and were subjected to standardization using pharmacognostical and phytochemical screening methods. Dose selection was made on the basis of acute oral toxicity study (50-5000 mg/kg b. w.) as per OECD guidelines. P. pinnata ethanolic extract (PPEE) and aqueous extract (PPAE) showed significant (P < 0.001) antidiabetic activity. In alloxan-induced model, blood glucose levels of these extracts on 7th day of the study were 155.83 ± 11.211mg/dl (PPEE) and 132.00 ± 4.955mg/dl (PPAE) in comparison of diabetic control (413.50 ± 4.752mg/dl) and chloroform extract (210.83 ± 14.912mg/dl). In glucose loaded rats, PPEE exhibited glucose level of 164.50 ± 6.350mg/dl after 30 min and 156.50 ± 4.089mg/dl after 90 min, whereas the levels in PPAE treated animals were 176 ± 3.724mg/dl after 30 min and 110.33 ± 6.687mg/dl after 90 min. These extracts also prevented body weight loss in diabetic rats. The drug has the potential to act as an antidiabetic drug.
Language	English
Publishing date	2011-03-24
Publishing country	India
Document type	Journal Article
ZDB-ID	2562172-5
ISSN	0974-925X ; 0974-7788
ISSN (online)	0974-925X
ISSN	0974-7788
DOI	10.4103/0974-7788.76780
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Automatic disease screening method using image processing for dried blood microfluidic drop stain pattern recognition.

Sikarwar, Basant S / Roy, Mukesh / Ranjan, Priya / Goyal, Ayush

Journal of medical engineering & technology

2016 Volume 40, Issue 5, Page(s) 245–254

Abstract: This paper examines programmed automatic recognition of infection from samples of dried stains of micro-scale drops of patient blood. This technique has the upside of being low-cost and less-intrusive and not requiring puncturing the patient with a ... ...

Abstract	This paper examines programmed automatic recognition of infection from samples of dried stains of micro-scale drops of patient blood. This technique has the upside of being low-cost and less-intrusive and not requiring puncturing the patient with a needle for drawing blood, which is especially critical for infants and the matured. It also does not require expensive pathological blood test laboratory equipment. The method is shown in this work to be successful for ailment identification in patients suffering from tuberculosis and anaemia. Illness affects the physical properties of blood, which thus influence the samples of dried micro-scale blood drop stains. For instance, if a patient has a severe drop in platelet count, which is often the case of dengue or malaria patients, the blood's physical property of viscosity drops substantially, i.e. the blood is thinner. Thus, the blood micro-scale drop stain samples can be utilised for diagnosing maladies. This paper presents programmed automatic examination of the dried micro-scale drop blood stain designs utilising an algorithm based on pattern recognition. The samples of micro-scale blood drop stains of ordinary non-infected people are clearly recognisable as well as the samples of micro-scale blood drop stains of sick people, due to key distinguishing features. As a contextual analysis, the micro-scale blood drop stains of patients infected with tuberculosis have been contrasted with the micro-scale blood drop stains of typical normal healthy people. The paper dives into the fundamental flow mechanics behind how the samples of the dried micro-scale blood drop stain is shaped. What has been found is a thick ring like feature in the dried micro-scale blood drop stains of non-ailing people and thin shape like lines in the dried micro-scale blood drop stains of patients with anaemia or tuberculosis disease. The ring like feature at the periphery is caused by an outward stream conveying suspended particles to the edge. Concentric rings (brought on by internal Marangoni flow) and deposition in the centre of the stain are patterns that were found in the dried micro-scale drop blood stain samples of ordinary healthy people.
Language	English
Publishing date	2016-07
Publishing country	England
Document type	Journal Article
ZDB-ID	243092-7
ISSN	1464-522X ; 0309-1902
ISSN (online)	1464-522X
ISSN	0309-1902
DOI	10.3109/03091902.2016.1162215
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 1970: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Wound healing activity of ethanolic extract of leaves of Eclipta alba

Shalini Sharma / Mukesh S Sikarwar

Pharmacognosy Magazine, Vol 4, Iss 13, Pp 108-

2008 Volume 111

Keywords	Medicine ; R ; Pharmacy and materia medica ; RS1-441
Publishing date	2008-01-01T00:00:00Z
Publisher	Medknow Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Antihyperlipidemic activity of Salacia chinensis root extracts in triton-induced and atherogenic diet-induced hyperlipidemic rats

Mukesh S Sikarwar / M B Patil

Indian Journal of Pharmacology, Vol 44, Iss 1, Pp 88-

2012 Volume 92

Abstract: ... expressed as mean΁ S.E. and data was analyzed by using one way analysis of variance test (ANOVA) followed ... by Dunnett′s t-test for multiple comparisons. Values with P < 0.05 were considered as significant. Results ...

Abstract	Objectives: The aim of this study has been to investigate the possible antihyperlipidemic effect of Salacia chinensis root extract in triton (400mg/kg b.w.)-induced and atherogenic diet-induced hyperlipidemic rats. Materials and Methods: Petroleum ether (60-80°C), chloroform, ethanol and aqueous extracts of Salacia chinensis roots were evaluated for antihyperlipidemic activity in triton- and atherogenic diet-induced hyperlipidemic rats. A comparison was also made between the action of Salacia chinensis root extract and a known antihyperlipidemic drug simvastatin (10 mg/kg body wt.). The results of the study were expressed as mean΁ S.E. and data was analyzed by using one way analysis of variance test (ANOVA) followed by Dunnett′s t-test for multiple comparisons. Values with P < 0.05 were considered as significant. Results: Oral administration of 500 mg/kg body wt. of the chloroform extract and alcoholic extract of Salacia chinensis root exhibited a significant reduction (P<0.01) in serum lipid parameters like total cholesterol, triglycerides, low density lipoprotein (LDL), very low density lipopreotein (VLDL) and increase in high density lipoprotein (HDL) in hyperlipidemic rats of both models as compared to hyperlipidemic control statistically. These extracts were found to possess better antihyperlipidemic potential as compared to pet ether and aqueous extract. Conclusions: Our results demonstrated that chloroform and alcoholic extract of Salacia chinensis roots possessed significant antihyperlipidemic activity and hence it could be a potential herbal medicine as adjuvant with existing therapy for the treatment of hyperlipidemia.
Keywords	Hyperlipidemia ; Salacia chinensis ; simvastatin ; triton ; Therapeutics. Pharmacology ; RM1-950 ; Medicine ; R
Language	English
Publishing date	2012-01-01T00:00:00Z
Publisher	Medknow Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Antidiabetic activity of Crateva nurvala stem bark extracts in alloxan-induced diabetic rats

Mukesh S Sikarwar / M B Patil

Journal of Pharmacy and Bioallied Sciences, Vol 2, Iss 1, Pp 18-

2010 Volume 21

Abstract: Objectives : The aim of this study was to investigate the antidiabetic activity of Crateva nurvala stem bark (family: Capparidaceae) extracts in alloxan-induced diabetic albino rats. A comparison was made between the action of different extracts of C. ... ...

Abstract	Objectives : The aim of this study was to investigate the antidiabetic activity of Crateva nurvala stem bark (family: Capparidaceae) extracts in alloxan-induced diabetic albino rats. A comparison was made between the action of different extracts of C. nurvala and a known antidiabetic drug glibenclamide (600 μg/kg b. wt.). An oral glucose tolerance test (OGTT) was also performed in diabetic rats. Materials and Methods : The petroleum ether, chloroform, alcohol, and aqueous extracts of C. nurvala stem bark were obtained by simple maceration method and were subjected to standardization by following pharmacognostical and phytochemical screening methods. Dose selection was made on the basis of acute oral toxicity study (50-5000 mg/kg b. wt.) as per Organization for Economic Co-operation and Development (OECD) guidelines. Results and Conclusions : C. nurvala petroleum ether extract (CNPEE) and ethanolic extract (CNEE) showed significant (P< 0.001) antidiabetic activities. In alloxan-induced model, blood glucose level of these extracts on seventh day of study were CNPEE (126.33±13.703 mg/dl) and CNEE (126.66±13.012 mg/dl) when compared with diabetic control (413.50±4.752 mg/dl) and chloroform extract (320.83±13.516 mg/dl). In OGGT model (glucose loaded rats), CNPEE showed a glucose level of 178.83±3.070 mg/dl after 30 min and 131.66±2.486 mg/dl after 90 min, whereas CNEE showed 173.66±4.224 mg/dl after 30 min and 115.50±3.394 mg/dl after 90 min. These extracts also prevented body weight loss in diabetic rats. The drug has the potential to act as an antidiabetic drug.
Keywords	Alloxan ; antidiabetic activity ; acute toxicity ; Crateva nurvala ; phytochemical ; Pharmacy and materia medica ; RS1-441 ; Analytical chemistry ; QD71-142
Language	English
Publishing date	2010-01-01T00:00:00Z
Publisher	Wolters Kluwer Medknow Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Aloe vera

Sikarwar Mukesh. S. / Patil M. B., / Bhat Vishnu / Sharma Shalini

International Journal of Pharma Sciences and Research , Vol 1, Iss 1, Pp 7-

Plant of Immortality

2010 Volume 10

Abstract: The Egyptians called Aloe the “Plant of Immortality” because it can live and even bloom without soil. Aloe has been used medicinally since at least the first century C.E. and continues to be used extensively worldwide. ...

Abstract	The Egyptians called Aloe the “Plant of Immortality” because it can live and even bloom without soil. Aloe has been used medicinally since at least the first century C.E. and continues to be used extensively worldwide.
Keywords	Grihakanya ; Kanya ; Ghritakumari ; Vipulasrava ; Sthuladala ; Dirgha patra ; Mandala ; Kumari ; Pharmacy and materia medica ; RS1-441 ; Medicine ; R ; DOAJ:Pharmacy and materia medica ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Language	English
Publishing date	2010-02-01T00:00:00Z
Publisher	KEJA Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Preparation, characterization and evaluation of Marsupsin-phospholipid complex.

Sikarwar, Mukesh S / Sharma, Shalini / Jain, Amit K / Parial, S D

AAPS PharmSciTech

2008 Volume 9, Issue 1, Page(s) 129–137

Abstract: The aim of this research was to formulate Marsupsin-phospholipid complex (M-P Complex) in attempt to increase the bioavailability of marsupsin and to characterize this new formulation along with its evaluation. Marsupsin-phospholipid complex was ... ...

Abstract	The aim of this research was to formulate Marsupsin-phospholipid complex (M-P Complex) in attempt to increase the bioavailability of marsupsin and to characterize this new formulation along with its evaluation. Marsupsin-phospholipid complex was formulated by mechanical dispersion method. In this new formulation, complex formation was confirmed by carrying out transmission electron microscopy (TEM), IR, (1)H-NMR and RP-HPLC analysis. TEM showed M-P Complex diameter range of 0.05-0.5 microm. The entrapment efficiency of M-P Complex was found to be 44%. In vitro release study revealed its first order release profile. Mean blood serum concentration vs time curve of marsupsin was of first order after oral administration of M-P Complex in albino rabbits which clearly showed remarkably increased bioavailability of M-P Complex than standardized marsupsin. The average value of C(max) and T(max) of M-P Complex were found to be 3.02 mg/ml and 10.2 h, respectively. Hence the findings demonstrate that complexing marsupsin with phospholipids results in better oral bioavailability and improved biological response than free form of standardized marsupsin.
MeSH term(s)	Animals ; Benzofurans/administration & dosage ; Benzofurans/chemistry ; Benzofurans/pharmacokinetics ; Cresols/administration & dosage ; Cresols/chemistry ; Cresols/pharmacokinetics ; Diabetes Mellitus/blood ; Diabetes Mellitus/drug therapy ; Diffusion ; Drug Carriers/chemistry ; Drug Compounding/methods ; Drug Evaluation, Preclinical ; Hypoglycemic Agents/administration & dosage ; Hypoglycemic Agents/chemistry ; Hypoglycemic Agents/pharmacokinetics ; Materials Testing ; Phospholipids/chemistry ; Rabbits ; Rats ; Treatment Outcome
Chemical Substances	Benzofurans ; Cresols ; Drug Carriers ; Hypoglycemic Agents ; Phospholipids ; marsupsin (83889-80-9)
Language	English
Publishing date	2008-01-18
Publishing country	United States
Document type	Evaluation Study ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2052070-0
ISSN	1530-9932 ; 1530-9932
ISSN (online)	1530-9932
ISSN	1530-9932
DOI	10.1208/s12249-007-9020-x
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito