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  1. Article: Anesthetic-induced anaphylaxis.

    Norred, Carol L

    AANA journal

    2012  Volume 80, Issue 2, Page(s) 129–140

    Abstract: The purpose of this course is to update nurse anesthetists about anesthetic-induced anaphylaxis. This course discusses the pathophysiologic process of anaphylaxis with descriptions of the allergic immune response and the mediators and mechanisms of mast ... ...

    Abstract The purpose of this course is to update nurse anesthetists about anesthetic-induced anaphylaxis. This course discusses the pathophysiologic process of anaphylaxis with descriptions of the allergic immune response and the mediators and mechanisms of mast cell activation. The preoperative identification of patients at high risk and the assessment of potential anesthetic triggers of a hypersensitivity and/or allergic reaction are prudent strategies to minimize the risk of anaphylaxis. Other practices recommended for clinicians include suggestions for anesthetic management to decrease threat of an allergic response in high-risk patients. Furthermore, the identification of the severity grade of hypersensitivity reactions and the appropriate treatment of perioperative anaphylaxis is discussed. In addition, postoperative and follow-up interventions, including testing for patients who have had an anesthetic-induced hypersensitivity reaction, are considered.
    MeSH term(s) Anaphylaxis/chemically induced ; Anaphylaxis/immunology ; Anaphylaxis/therapy ; Anesthesia/adverse effects ; Drug Hypersensitivity/immunology ; Drug Hypersensitivity/therapy ; Education, Nursing, Continuing ; Humans ; Nurse Anesthetists
    Language English
    Publishing date 2012-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 603605-3
    ISSN 0094-6354
    ISSN 0094-6354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Antiemetic prophylaxis: pharmacology and therapeutics.

    Norred, Carol L

    AANA journal

    2003  Volume 71, Issue 2, Page(s) 133–140

    Abstract: Postoperative nausea and vomiting (PONV), a common problem with complex causes, may result in substantial complications. This Journal course discusses the pathogenesis of PONV and reviews antiemetic pharmacology. Corticosteroids, gastrointestinal ... ...

    Abstract Postoperative nausea and vomiting (PONV), a common problem with complex causes, may result in substantial complications. This Journal course discusses the pathogenesis of PONV and reviews antiemetic pharmacology. Corticosteroids, gastrointestinal prokinetics, neuroleptic butyrophenones, phenothiazines, and serotonin receptor antagonists may be prescribed alone or in combination. State-of-the-art anesthetic techniques for prevention of PONV are described. Multimodal therapy with combined low-dose antiemetics affecting multiple receptors is suggested to prevent PONV in high-risk patients such as nonsmokers, females with a previous history of nausea, and patients with high postoperative narcotic requirements.
    MeSH term(s) Antiemetics/therapeutic use ; Education, Nursing, Continuing ; Humans ; Nurse Anesthetists ; Postoperative Nausea and Vomiting/drug therapy ; Postoperative Nausea and Vomiting/physiopathology ; Postoperative Nausea and Vomiting/prevention & control
    Chemical Substances Antiemetics
    Language English
    Publishing date 2003-04
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S. ; Review
    ZDB-ID 603605-3
    ISSN 0094-6354
    ISSN 0094-6354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Prevention of postoperative nausea and vomiting.

    Norred, Carol L

    AANA journal

    2002  Volume 70, Issue 5, Page(s) 343–344

    MeSH term(s) Antiemetics/adverse effects ; Contraindications ; Droperidol/adverse effects ; Humans ; Postoperative Nausea and Vomiting/drug therapy ; Postoperative Nausea and Vomiting/prevention & control
    Chemical Substances Antiemetics ; Droperidol (O9U0F09D5X)
    Language English
    Publishing date 2002-10
    Publishing country United States
    Document type Letter
    ZDB-ID 603605-3
    ISSN 0094-6354
    ISSN 0094-6354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: A follow-up survey of the use of complementary and alternative medicines by surgical patients.

    Norred, Carol L

    AANA journal

    2002  Volume 70, Issue 2, Page(s) 119–125

    Abstract: This study investigated the use of complementary and alternative medicines by surgical patients at the University of Colorado Health Sciences Center, Denver. Elective surgical outpatients were randomly surveyed with anonymous self-report questionnaires ... ...

    Abstract This study investigated the use of complementary and alternative medicines by surgical patients at the University of Colorado Health Sciences Center, Denver. Elective surgical outpatients were randomly surveyed with anonymous self-report questionnaires during day-surgery admission about alternative medicines taken during the 2 weeks before surgery; 496 of 500 questionnaires were completed and returned. Of the patients, 37% reported 62 types of herbs, 59% reported 14 types of vitamins, 45% reported 36 types of of dietary supplements, and 1% reported taking 5 types of homeopathics. A total of 73.4% of patients took alternative medicines preoperatively (range, 1-44 medicines). After a literature review, the alternative medicines were categorized for potential interactions with anesthetic drugs. Alternative medicines that have inhibitory effects on the coagulation cascade were reported by 40% of surgical patients. The following percentages of patients took medicines that affect blood pressure, 32%; affect cardiac function, 20%; cause sedation, 17%; or have potential to alter electrolyte levels, 9%. Herbs recognized to interact with pharmaceuticals were consumed by 23% of patients. Further research, education, and improved communication are needed to safely integrate alternative medicines for surgical patients.
    MeSH term(s) Adult ; Anesthetics/adverse effects ; Complementary Therapies/adverse effects ; Complementary Therapies/statistics & numerical data ; Complementary Therapies/utilization ; Data Collection ; Drug Interactions ; Female ; Follow-Up Studies ; Humans ; Male ; Outpatients/statistics & numerical data ; Plant Preparations/adverse effects ; Preoperative Care
    Chemical Substances Anesthetics ; Plant Preparations
    Language English
    Publishing date 2002-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 603605-3
    ISSN 0094-6354
    ISSN 0094-6354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Complementary and alternative medicine use by surgical patients.

    Norred, Carol L

    AORN journal

    2002  Volume 76, Issue 6, Page(s) 1013–1021

    Abstract: This national multisite study examined complementary and alternative medicine (CAM) use by surgical patients during the two weeks preceding their surgery. A simple descriptive design consisting of anonymous self-report questionnaires was used to measure ... ...

    Abstract This national multisite study examined complementary and alternative medicine (CAM) use by surgical patients during the two weeks preceding their surgery. A simple descriptive design consisting of anonymous self-report questionnaires was used to measure CAM use and determine participant demographics. A purposive sample of adult, English-speaking, elective outpatients from 16 hospitals representing seven US regions was used. Data were collected randomly at each site. Sixty-seven percent of participants disclosed use of all types of CAM; 27% consumed herbs, 39% used dietary supplements, 54% took vitamins, and 1% reported use of homeopathics. Thirty-four percent of participants reported using CAMs that potentially can interact with anesthetics and inhibit coagulation. The results of this study suggest that perioperative nurses should encourage patients to disclose CAM use and should educate patients about anesthetic interactions that may contribute to bleeding.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Ambulatory Surgical Procedures ; Anesthesia/adverse effects ; Blood Coagulation/drug effects ; Complementary Therapies/adverse effects ; Complementary Therapies/statistics & numerical data ; Contraindications ; Drug Interactions ; Female ; Humans ; Male ; Middle Aged ; Perioperative Nursing ; Preoperative Care/adverse effects ; Risk Factors ; Surgical Procedures, Operative/nursing ; Surveys and Questionnaires ; United States
    Language English
    Publishing date 2002-12
    Publishing country United States
    Document type Journal Article ; Multicenter Study
    ZDB-ID 603972-8
    ISSN 0001-2092
    ISSN 0001-2092
    DOI 10.1016/s0001-2092(06)61003-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Use of complementary and alternative medications by surgical patients.

    Wren, Kathleen R / Kimbrall, Shannon / Norred, Carol L

    Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses

    2002  Volume 17, Issue 3, Page(s) 170–177

    Abstract: Complementary and alternative medication (CAM) use is increasing in popularity across the United States. Not surprisingly, health care providers' encounters with patients who use these medications are increasing as well. The manufacturing and production ... ...

    Abstract Complementary and alternative medication (CAM) use is increasing in popularity across the United States. Not surprisingly, health care providers' encounters with patients who use these medications are increasing as well. The manufacturing and production of CAM are not strictly regulated in contrast to prescription and other over-the-counter medications. As such, it is difficult for health care providers to assess the likelihood of side effects, toxic effects, or drug-drug interactions in the perianesthesia period. Additionally, many patients and providers are unaware of the many complications and drug interactions associated with CAMs. This study explored CAM use in ambulatory surgical patients at a metropolitan, level 1 trauma center in the Southeast. Five hundred patients were randomly surveyed regarding CAM use during the 2 weeks before their surgical procedure. The frequency of CAM use was assessed and tabulated in relationship to potential pharmacodynamic effects and interactions, such as sedation, coagulation, blood pressure effects, cardiac effects, electrolyte alterations, and potential drug interactions. Descriptive statistics were used to assess gender, age, education, ethnicity, and surgery type. This study found that during the 2 weeks before surgery, 208 patients (42.7%) consumed CAMs. Ninety-two patients (19.8%) took CAMS that inhibit coagulation. Seventy patients (14.4%) used CAMs that affect blood pressure, and 36 patients (7.4%) used CAMs with cardiac effects. Thirty-nine patients (8%) consumed CAMs with sedative effects. The results of this study will assist perianesthesia nurses in patient education, preanesthesia patient assessment, and perianesthesia care planning.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Complementary Therapies/statistics & numerical data ; Drug Interactions ; Herbal Medicine ; Humans ; Middle Aged ; Surveys and Questionnaires ; United States
    Language English
    Publishing date 2002-05-31
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1329844-6
    ISSN 1089-9472 ; 0883-9433
    ISSN 1089-9472 ; 0883-9433
    DOI 10.1053/jpan.2002.33621
    Database MEDical Literature Analysis and Retrieval System OnLINE

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