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  1. Article: Anmerkungen zum Beitrag von Christian Holzner und Sonja Munz (2013)

    Hujer, Reinhard / Holzner, Christian / Munz, Sonja

    Journal for labour market research Vol. 47, No. 3 , p. 181

    "Should local public employment services be merged with local social benefit administrations?" (Vol. 46, No. 2, S. 83-1029

    2014  Volume 47, Issue 3, Page(s) 181

    Author's details Reinhard Hujer
    Language English
    Publisher Springer
    Publishing place Berlin ; Heidelberg
    Document type Article
    ZDB-ID 2157761-4
    ISSN 1614-3485
    Database ECONomics Information System

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  2. Article ; Online: Degrade to stay healthy-Proteolytic interplay during inflammation.

    Münz, Christian

    PLoS biology

    2024  Volume 22, Issue 3, Page(s) e3002548

    Abstract: Proteasomes and autophagy constitute the 2 main proteolytic machineries for cytoplasmic content. A new study in PLOS Biology now demonstrates that autophagy stimulation alters proteasome composition, degrading hyperactive immunoproteasomes and thereby ... ...

    Abstract Proteasomes and autophagy constitute the 2 main proteolytic machineries for cytoplasmic content. A new study in PLOS Biology now demonstrates that autophagy stimulation alters proteasome composition, degrading hyperactive immunoproteasomes and thereby limiting inflammation.
    MeSH term(s) Humans ; Proteasome Endopeptidase Complex/metabolism ; Proteolysis ; Inflammation ; Macrophages/metabolism ; Autophagy
    Chemical Substances Proteasome Endopeptidase Complex (EC 3.4.25.1)
    Language English
    Publishing date 2024-03-07
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2126776-5
    ISSN 1545-7885 ; 1544-9173
    ISSN (online) 1545-7885
    ISSN 1544-9173
    DOI 10.1371/journal.pbio.3002548
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6193: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Altered EBV specific immune control in multiple sclerosis.

    Münz, Christian

    Journal of neuroimmunology

    2024  Volume 390, Page(s) 578343

    Abstract: Since the 1980s it is known that immune responses to the Epstein-Barr virus (EBV) are elevated in multiple sclerosis (MS) patients. Recent seroepidemiologial data have shown that this alteration after primary EBV infection identifies individuals with a ... ...

    Abstract Since the 1980s it is known that immune responses to the Epstein-Barr virus (EBV) are elevated in multiple sclerosis (MS) patients. Recent seroepidemiologial data have shown that this alteration after primary EBV infection identifies individuals with a more than 30-fold increased risk to develop MS. The mechanisms by which EBV infection might erode tolerance for the central nervous system (CNS) in these individuals, years prior to clinical MS onset, remain unclear. In this review I will discuss altered frequencies of EBV life cycle stages and their tissue distribution, EBV with CNS autoantigen cross-reactive immune responses and loss of immune control for autoreactive B and T cells as possible mechanisms. This discussion is intended to stimulate future studies into these mechanisms with the aim to identify candidates for interventions that might correct EBV specific immune control and/or resulting cross-reactivities with CNS autoantigens in MS patients and thereby ameliorate disease activity.
    Language English
    Publishing date 2024-04-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 8335-5
    ISSN 1872-8421 ; 0165-5728
    ISSN (online) 1872-8421
    ISSN 0165-5728
    DOI 10.1016/j.jneuroim.2024.578343
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1646: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  4. Book ; Collection: Epstein Barr Virus

    Münz, Christian

    one herpes virus – many diseases

    (Current topics in microbiology and immunology ; ...)

    2015  

    Author's details Christian Münz ed
    Series title Current topics in microbiology and immunology
    ...
    Language English
    Dates of publication 2015-9999
    Publisher Springer
    Publishing place Cham u.a.
    Publishing country Switzerland
    Document type Book ; Collection (display volumes)
    HBZ-ID HT018804159
    Database Catalogue ZB MED Medicine, Health

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  5. Article: Modulation of Epstein-Barr-Virus (EBV)-Associated Cancers by Co-Infections.

    Münz, Christian

    Cancers

    2023  Volume 15, Issue 24

    Abstract: The oncogenic and persistent Epstein Barr virus (EBV) is carried by more than 95% of the human adult population. While asymptomatic in most of these, EBV can cause a wide variety of malignancies of lymphoid or epithelial cell origin. Some of these are ... ...

    Abstract The oncogenic and persistent Epstein Barr virus (EBV) is carried by more than 95% of the human adult population. While asymptomatic in most of these, EBV can cause a wide variety of malignancies of lymphoid or epithelial cell origin. Some of these are also associated with co-infections that either increase EBV-induced tumorigenesis or weaken its immune control. The respective pathogens include Kaposi-sarcoma-associated herpesvirus (KSHV),
    Language English
    Publishing date 2023-12-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15245739
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Epstein Barr Virus / 2

    Münz, Christian

    one herpes virus – many diseases

    (Current topics in microbiology and immunology ; 391)

    2015  

    Author's details Christian Münz ed
    Series title Current topics in microbiology and immunology ; 391
    Epstein Barr Virus
    Collection Epstein Barr Virus
    Keywords human tumor virus ; persistent infection ; immunotherapies ; cell-mediated immune control ; lymphomas and carcinomas
    Language English
    Size VI, 505 S.: Ill., graph. Darst., 235 mm x 155 mm, 0 g
    Publisher Springer
    Publishing place Cham u.a.
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT018804185
    ISBN 978-3-319-22833-4 ; 978-3-319-22834-1 ; 3-319-22833-1 ; 3-319-22834-X
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Ud II Zs 24 -391- verfügbar in Königswinter Königswinter

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  7. Book: Epstein Barr Virus / 1

    Münz, Christian

    one herpes virus – many diseases

    (Current topics in microbiology and immunology ; 390)

    2015  

    Author's details Christian Münz ed
    Series title Current topics in microbiology and immunology ; 390
    Epstein Barr Virus
    Collection Epstein Barr Virus
    Keywords human tumor virus ; persistent infection ; immunotherapies ; cell-mediated immune control ; lymphomas and carcinomas
    Language English
    Size VIII, 391 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place Cham u.a.
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT018804152
    ISBN 978-3-319-22821-1 ; 978-3-319-22822-8 ; 3-319-22821-8 ; 3-319-22822-6
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Ud II Zs 24 -390- verfügbar in Königswinter Königswinter

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  8. Article ; Online: Immune control of human γ-herpes infections.

    Münz, Christian

    Seminars in arthritis and rheumatism

    2023  Volume 64S, Page(s) 152320

    Abstract: Recent evidence suggests that infection with the Epstein Barr virus (EBV) initiates a prodromal phase of multiple sclerosis (MS) in individuals with genetic and environmental predispositions for this autoimmune disease. In the context of the main genetic ...

    Abstract Recent evidence suggests that infection with the Epstein Barr virus (EBV) initiates a prodromal phase of multiple sclerosis (MS) in individuals with genetic and environmental predispositions for this autoimmune disease. In the context of the main genetic risk factor, the major histocompatibility complex (MHC) class II molecule HLA-DRB1*1501, EBV infection is less well controlled in a preclinical mouse model. CD4
    MeSH term(s) Animals ; Mice ; Humans ; Epstein-Barr Virus Infections/complications ; Herpesvirus 4, Human/genetics ; HLA-DRB1 Chains/genetics ; T-Lymphocytes ; Multiple Sclerosis ; Autoantigens
    Chemical Substances HLA-DRB1 Chains ; Autoantigens
    Language English
    Publishing date 2023-11-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 120247-9
    ISSN 1532-866X ; 0049-0172
    ISSN (online) 1532-866X
    ISSN 0049-0172
    DOI 10.1016/j.semarthrit.2023.152320
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 790: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Canonical and Non-Canonical Functions of the Autophagy Machinery in MHC Restricted Antigen Presentation.

    Münz, Christian

    Frontiers in immunology

    2022  Volume 13, Page(s) 868888

    Abstract: Macroautophagy delivers cytoplasmic constituents for lysosomal degradation. Since major histocompatibility complex (MHC) class II molecules sample peptides after lysosomal degradation for presentation to ... ...

    Abstract Macroautophagy delivers cytoplasmic constituents for lysosomal degradation. Since major histocompatibility complex (MHC) class II molecules sample peptides after lysosomal degradation for presentation to CD4
    MeSH term(s) Antigen Presentation ; Antigens ; Autophagy ; Histocompatibility Antigens Class I ; Histocompatibility Antigens Class II ; Macroautophagy ; Phagocytosis
    Chemical Substances Antigens ; Histocompatibility Antigens Class I ; Histocompatibility Antigens Class II
    Language English
    Publishing date 2022-03-04
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2022.868888
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Natural killer cell responses to human oncogenic γ-herpesvirus infections.

    Münz, Christian

    Seminars in immunology

    2022  Volume 60, Page(s) 101652

    Abstract: The two γ-herpesviruses Epstein Barr virus (EBV) and Kaposi sarcoma associated herpesvirus (KSHV) are each associated with more than 1% of all tumors in humans. While EBV establishes persistent infection in nearly all adult individuals, KSHV benefits ... ...

    Abstract The two γ-herpesviruses Epstein Barr virus (EBV) and Kaposi sarcoma associated herpesvirus (KSHV) are each associated with more than 1% of all tumors in humans. While EBV establishes persistent infection in nearly all adult individuals, KSHV benefits from this widespread EBV prevalence for its own persistence. Interestingly, EBV infection expands early differentiated NKG2A
    Language English
    Publishing date 2022-09-23
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1018141-6
    ISSN 1096-3618 ; 1044-5323
    ISSN (online) 1096-3618
    ISSN 1044-5323
    DOI 10.1016/j.smim.2022.101652
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2843: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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