LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 5503

Search options

  1. Article: Citation for the 1999 Ernst Oppenheimer Award of The Endocrine Society to Dr. David W. Russell.

    Wilson, J D

    Endocrine reviews

    1998  Volume 20, Issue 4, Page(s) 587–588

    MeSH term(s) Awards and Prizes ; Endocrinology/history ; History, 20th Century ; Humans ; Societies, Scientific ; United States
    Language English
    Publishing date 1998-07-21
    Publishing country United States
    Document type Biography ; Historical Article ; Journal Article ; Portrait
    ZDB-ID 603096-8
    ISSN 1945-7189 ; 0163-769X
    ISSN (online) 1945-7189
    ISSN 0163-769X
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Book ; Online: Biological Invasions in South Africa

    van Wilgen, Brian W. / Measey, John / Richardson, David M. / Wilson, John R. / Zengeya, Tsungai A.

    (Invading Nature - Springer Series in Invasion Ecology ; 14)

    2020  

    Author's details edited by Brian W. van Wilgen, John Measey, David M. Richardson, John R. Wilson, Tsungai A. Zengeya
    Series title Invading Nature - Springer Series in Invasion Ecology ; 14
    Keywords Biodiversity ; Conservation biology ; Ecology  ; Animal systematics ; Animal taxonomy ; Ecosystems ; Plant pathology ; Südafrika ; Biologie ; Zoologie ; Botanik
    Subject Pflanzenkunde ; Phytologie ; Tierkunde ; Allgemeine Biologie
    Subject code 577
    Language English
    Size 1 Online-Ressource (XXIV, 975 p. 155 illus., 111 illus. in color)
    Edition 1st ed. 2020
    Publisher Springer International Publishing ; Imprint: Springer
    Publishing place Cham
    Document type Book ; Online
    HBZ-ID HT020411241
    ISBN 978-3-030-32394-3 ; 9783030323936 ; 9783030323950 ; 9783030323967 ; 3-030-32394-3 ; 3030323935 ; 3030323951 ; 303032396X
    DOI 10.1007/978-3-030-32394-3
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    More links

    Kategorien

  3. Book ; Online: (Table S1) Chronostratigraphic constrains for sediment core AND1-1B, supplementary data to: Naish, Tim R; Powell, Ross; Levy, R; Wilson, Gary S; Scherer, Reed P; Talarico, Franco; Krissek, Lawrence A; Niessen, Frank; Pompilio, Massimo; Wilson, Terry; Carter, Lionel; DeConto, Robert M; Huybers, P; McKay, R; Pollard, David; Ross, J; Winter, Diane M; Barrett, Peter J; Browne, G; Cody, R; Cowan, Ellen A; Crampton, J; Dunbar, Gavin B; Dunbar, N; Florindo, Fabio; Gebhardt, Andrea Catalina; Graham, IJ; Hannah, Mike J; Hansaraj, D; Harwood, David M; Helling, D; Henrys, Stuart; Hinnov, L; Kuhn, Gerhard; Kyle, Philip R; Läufer, Andreas L; Maffioli, P; Magens, Diana; Mandernack, Kevin W; McIntosh, WC; Millan, C; Morin, Roger H; Ohneiser, Christian; Paulsen, Timothy S; Persico, Davide; Raine, J Ian; Reed, J; Riesselman, C; Sagnotti, Leo; Schmitt, D R; Sjunneskog, C; Strong, P; Taviani, Marco; Vogel, Stefan; Wilch, T; Williams, Trevor (2009): Obliquity-paced Pliocene West Antarctic ice sheet oscillations. Nature, 458(7236), 322-329

    Naish, Tim R / Krissek, Lawrence A / Levy, R / Niessen, Frank / Pompilio, Massimo / Powell, Ross / Scherer, Reed P / Talarico, Franco / Wilson, Gary S / al., et

    2009  

    Abstract: Thirty years after oxygen isotope records from microfossils deposited in ocean sediments confirmed the hypothesis that variations in the Earth's orbital geometry control the ice ages (Hays et al., 1976, doi:10.1126/science.194.4270.1121), fundamental ... ...

    Abstract Thirty years after oxygen isotope records from microfossils deposited in ocean sediments confirmed the hypothesis that variations in the Earth's orbital geometry control the ice ages (Hays et al., 1976, doi:10.1126/science.194.4270.1121), fundamental questions remain over the response of the Antarctic ice sheets to orbital cycles (Raymo and Huybers, 2008, doi:10.1038/nature06589). Furthermore, an understanding of the behaviour of the marine-based West Antarctic ice sheet (WAIS) during the 'warmer-than-present' early-Pliocene epoch (~5-3 Myr ago) is needed to better constrain the possible range of ice-sheet behaviour in the context of future global warming (Solomon et al., 2007). Here we present a marine glacial record from the upper 600 m of the AND-1B sediment core recovered from beneath the northwest part of the Ross ice shelf by the ANDRILL programme and demonstrate well-dated, ~40-kyr cyclic variations in ice-sheet extent linked to cycles in insolation influenced by changes in the Earth's axial tilt (obliquity) during the Pliocene. Our data provide direct evidence for orbitally induced oscillations in the WAIS, which periodically collapsed, resulting in a switch from grounded ice, or ice shelves, to open waters in the Ross embayment when planetary temperatures were up to ~3° C warmer than today ( Kim and Crowley, 2000, doi:10.1029/1999PA000459) and atmospheric CO2 concentration was as high as ~400 p.p.m.v. (van der Burgh et al., 1993, doi:10.1126/science.260.5115.1788, Raymo et al., 1996, doi:10.1016/0377-8398(95)00048-8). The evidence is consistent with a new ice-sheet/ice-shelf model (Pollard and DeConto, 2009, doi:10.1038/nature07809) that simulates fluctuations in Antarctic ice volume of up to +7 m in equivalent sea level associated with the loss of the WAIS and up to +3 m in equivalent sea level from the East Antarctic ice sheet, in response to ocean-induced melting paced by obliquity. During interglacial times, diatomaceous sediments indicate high surface-water productivity, minimal summer sea ice and air temperatures above freezing, suggesting an additional influence of surface melt (Huybers, 2006, doi:10.1126/science.1125249) under conditions of elevated CO2.
    Language English
    Dates of publication 2009-9999
    Size Online-Ressource
    Publisher PANGAEA - Data Publisher for Earth & Environmental Science
    Publishing place Bremen/Bremerhaven
    Document type Book ; Online
    Note This dataset is supplement to doi:10.1038/nature07867
    DOI 10.1594/PANGAEA.769658
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

    More links

    Kategorien

  4. Book ; Online: Biological Invasions in South Africa

    van Wilgen, Brian W. / Measey, John / Richardson, David M. / Wilson, John R. / Zengeya, Tsungai A. / Richardson, David M.

    2020  

    Keywords Biodiversity ; Conservation of the environment ; Ecological science, the Biosphere ; Zoology & animal sciences ; Plant pathology & diseases ; Conservation Biology/Ecology ; Ecology ; Animal Systematics/Taxonomy/Biogeography ; Ecosystems ; Plant Pathology ; Conservation Biology ; Freshwater and Marine Ecology ; Biological Taxonomy ; South Africa ; Terrestrial ; Vertebrate invasions ; Aquatic plants ; Freshwater ecosystems ; Invasive biota ; Prince Edward Islands ; Coastal invasions ; Pathogens ; Urban invasions ; Alien organisms ; Abiotic factors ; Agricultural crops ; Invasive insect pests ; Open Access ; Taxonomy & systematics ; Botany & plant sciences ; Südafrika ; Biologie ; Zoologie ; Botanik
    Subject Pflanzenkunde ; Phytologie ; Tierkunde ; Allgemeine Biologie
    Size 1 electronic resource (975 pages)
    Publisher Springer Nature
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021048442
    ISBN 9783030323943 ; 3030323943
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    More links

    Kategorien

  5. Article ; Online: Reactive transport modelling of tailings hydrogeochemistry under a composite cover.

    Zhang, Aria / Wilson, David / Ptacek, Carol J / Blowes, David W

    Journal of contaminant hydrology

    2023  Volume 261, Page(s) 104290

    Abstract: Quantitative forecasts of acid mine drainage (AMD) production are important for remediation planning. Reactive transport simulations corresponding to a detailed sampling location at a covered legacy tailings impoundment in northern Ontario, Canada, were ... ...

    Abstract Quantitative forecasts of acid mine drainage (AMD) production are important for remediation planning. Reactive transport simulations corresponding to a detailed sampling location at a covered legacy tailings impoundment in northern Ontario, Canada, were conducted to quantitatively assess the predominant hydrogeochemical reactions. The simulations span the period from the end of tailings deposition (circa 1970) to early 2020, 12 years after remediation by a five-layer composite cover. The conceptual model of uncovered tailings weathering and subsequent geochemistry of the covered tailings system was implemented in 1D using the multi-component reactive transport code MIN3P. Transient monthly infiltration, post-cover boundary condition changes, and a dynamic temperature regime were incorporated. The shrinking core model, including parallel O
    MeSH term(s) Minerals/analysis ; Oxidation-Reduction ; Ontario ; Sulfides
    Chemical Substances Minerals ; Sulfides
    Language English
    Publishing date 2023-12-30
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1494766-3
    ISSN 1873-6009 ; 0169-7722
    ISSN (online) 1873-6009
    ISSN 0169-7722
    DOI 10.1016/j.jconhyd.2023.104290
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Binding to the DNA Minor Groove by Heterocyclic Dications: from AT Specific to GC Recognition Compounds.

    Paul, Ananya / Nanjunda, Rupesh / Wilson, W David

    Current protocols

    2023  Volume 3, Issue 4, Page(s) e729

    Abstract: Compounds that bind in the DNA minor groove have provided critical information on DNA molecular recognition, have found extensive uses in biotechnology, and are providing clinically useful drugs against diseases as diverse as cancer and sleeping sickness. ...

    Abstract Compounds that bind in the DNA minor groove have provided critical information on DNA molecular recognition, have found extensive uses in biotechnology, and are providing clinically useful drugs against diseases as diverse as cancer and sleeping sickness. This review focuses on the development of clinically useful heterocyclic diamidine minor groove binders. These compounds show that the classical model for minor groove binding in AT DNA sequences must be expanded in several ways: compounds with nonstandard shapes can bind strongly to the groove, water can be directly incorporated into the minor groove complex in an interfacial interaction, compounds can be designed to recognize GC and mixed AT/GC base pair sequences, and stacked dimers can form to recognize specific sequences. © 2023 Wiley Periodicals LLC.
    MeSH term(s) Surface Plasmon Resonance ; Binding Sites ; DNA/chemistry ; DNA/metabolism ; Base Pairing ; Pentamidine
    Chemical Substances DNA (9007-49-2) ; Pentamidine (673LC5J4LQ)
    Language English
    Publishing date 2023-04-18
    Publishing country United States
    Document type Review ; Journal Article
    ISSN 2691-1299
    ISSN (online) 2691-1299
    DOI 10.1002/cpz1.729
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article: Physiological condition infers habitat choice in juvenile sockeye salmon.

    LoScerbo, Daniella C / Wilson, Samantha M / Robinson, Kendra A / Moore, Jonathan W / Patterson, David A

    Conservation physiology

    2024  Volume 12, Issue 1, Page(s) coae011

    Abstract: The amount of time that juvenile salmon remain in an estuary varies among and within populations, with some individuals passing through their estuary in hours while others remain in the estuary for several months. Underlying differences in individual ... ...

    Abstract The amount of time that juvenile salmon remain in an estuary varies among and within populations, with some individuals passing through their estuary in hours while others remain in the estuary for several months. Underlying differences in individual physiological condition, such as body size, stored energy and osmoregulatory function, could drive individual variation in the selection of estuary habitat. Here we investigated the role of variation in physiological condition on the selection of estuarine and ocean habitat by sockeye salmon (
    Language English
    Publishing date 2024-04-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2721508-8
    ISSN 2051-1434
    ISSN 2051-1434
    DOI 10.1093/conphys/coae011
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Testosterone-Induced Central Serous Chorioretinopathy Mimicking a Choroidal Mass.

    Kornblau, Ilyse S / Pritchett, David Y / Wilson, Matthew W

    Retinal cases & brief reports

    2023  

    Abstract: Purpose: To describe a case of supplemental testosterone-induced central serous chorioretinopathy (CSCR) mimicking a choroidal mass in a 63-year-old male.: Methods: Case report.: Patient: A 63-year-old male patient on self-prescribed supplemental ... ...

    Abstract Purpose: To describe a case of supplemental testosterone-induced central serous chorioretinopathy (CSCR) mimicking a choroidal mass in a 63-year-old male.
    Methods: Case report.
    Patient: A 63-year-old male patient on self-prescribed supplemental testosterone with CSCR mimicking a choroidal mass.
    Results: A 63-year-old male presented with new onset vision loss, subretinal fluid, and choroidal mass in his left eye. Intravenous fluorescein angiography showed an enhancing choroidal mass involving the fovea. B scan ultrasonography revealed diffuse choroidal thickening. Given concern for a diffuse uveal melanoma, the lesion was biopsied showing non-diagnostic rare, atypical melanocytes. Four months after initial presentation, the patient was diagnosed with polycythemia vera. Fourteen months after diagnosis, he admitted to testosterone supplementation. Upon cessation of the testosterone supplement, the lesion progressively flattened to a chorioretinal scar with subretinal fluid resolution, and the return of normal choroidal thickness over the next 14 months.
    Discussion: Testosterone supplementation has been linked to erythrocytosis and polycythemia vera. In the retina, testosterone supplementation has been linked to CSCR and both central and branch retinal artery and vein occlusions. This case demonstrates the importance of inquiring about all prescribed and over the counter medications in patients presenting with retinal lesions of unknown origin.
    Language English
    Publishing date 2023-09-04
    Publishing country United States
    Document type Journal Article
    ISSN 1937-1578
    ISSN (online) 1937-1578
    DOI 10.1097/ICB.0000000000001482
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: Thermodynamic Factors That Drive Sequence-Specific DNA Binding of Designed, Synthetic Minor Groove Binding Agents.

    Paul, Ananya / Farahat, Abdelbasset A / Boykin, David W / Wilson, W David

    Life (Basel, Switzerland)

    2022  Volume 12, Issue 5

    Abstract: Ken Breslauer began studies on the thermodynamics of small cationic molecules binding in the DNA minor groove over 30 years ago, and the studies reported here are an extension of those ground-breaking reports. The goals of this report are to develop a ... ...

    Abstract Ken Breslauer began studies on the thermodynamics of small cationic molecules binding in the DNA minor groove over 30 years ago, and the studies reported here are an extension of those ground-breaking reports. The goals of this report are to develop a detailed understanding of the binding thermodynamics of pyridine-based sequence-specific minor groove binders that have different terminal cationic groups. We apply biosensor-surface plasmon resonance and ITC methods to extend the understanding of minor groove binders in two directions: (i) by using designed, heterocyclic dicationic minor groove binders that can incorporate a G•C base pair (bp), with flanking AT base pairs, into their DNA recognition site, and bind to DNA sequences specifically; and (ii) by using a range of flanking AT sequences to better define molecular recognition of the minor groove. A G•C bp in the DNA recognition site causes a generally more negative binding enthalpy than with most previously used pure AT binding sites. The binding is enthalpy-driven at 25 °C and above. The flanking AT sequences also have a large effect on the binding energetics with the -AAAGTTT- site having the strongest affinity. As a result of these studies, we now have a much better understanding of the effects of the DNA sequence and compound structure on the molecular recognition and thermodynamics of minor groove complexes.
    Language English
    Publishing date 2022-05-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life12050681
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Antimicrobial Selection for the Equine Practitioner.

    Wilson, W David / Magdesian, K Gary

    The Veterinary clinics of North America. Equine practice

    2021  Volume 37, Issue 2, Page(s) 461–494

    Abstract: Antimicrobial drugs play an important, often central, role in the therapeutic management of mature horses and foals with a variety of illnesses, including those requiring critical care. Antimicrobial use must be based on rational principles involving ... ...

    Abstract Antimicrobial drugs play an important, often central, role in the therapeutic management of mature horses and foals with a variety of illnesses, including those requiring critical care. Antimicrobial use must be based on rational principles involving thorough patient evaluation and sound clinical judgment that indicate a high likelihood that the patient has a bacterial infection and that antimicrobials are indicated to promote recovery. The aim of antimicrobial treatment is to inflict an insult on infecting bacteria sufficient to kill the organism or render it susceptible to inactivation by natural host defenses or the local microenvironment without adversely affecting the patient.
    MeSH term(s) Animals ; Anti-Infective Agents/therapeutic use ; Antimicrobial Stewardship ; Bacterial Infections/drug therapy ; Bacterial Infections/microbiology ; Bacterial Infections/veterinary ; Drug Resistance, Bacterial ; Horse Diseases/drug therapy ; Horse Diseases/microbiology ; Horses
    Chemical Substances Anti-Infective Agents
    Language English
    Publishing date 2021-06-14
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 286049-1
    ISSN 1558-4224 ; 0749-0739
    ISSN (online) 1558-4224
    ISSN 0749-0739
    DOI 10.1016/j.cveq.2021.04.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top