Article ; Online: Variability of neonatal premedication practices for endotracheal intubation and LISA in the UK (NeoPRINT survey).
2023 Volume 183, Page(s) 105808
Abstract: Objective: The NeoPRINT Survey was designed to assess premedication practices throughout UK NHS Trusts for both neonatal endotracheal intubation and less invasive surfactant administration (LISA).: Design: An online survey consisting of multiple ... ...
Abstract | Objective: The NeoPRINT Survey was designed to assess premedication practices throughout UK NHS Trusts for both neonatal endotracheal intubation and less invasive surfactant administration (LISA). Design: An online survey consisting of multiple choice and open answer questions covering preferences of premedication for endotracheal intubation and LISA was distributed over a 67-day period. Responses were then analysed using STATA IC 16.0. Setting: Online survey distributed to all UK Neonatal Units (NNUs). Participants: The survey evaluated premedication practices for endotracheal intubation and LISA in neonates requiring these procedures. Main outcome measures: The use of different premedication categories as well as individual medications within each category was analysed to create a picture of typical clinical practice across the UK. Results: The response rate for the survey was 40.8 % (78/191). Premedication was used in all hospitals for endotracheal intubation but overall, 50 % (39/78) of the units that have responded, use premedications for LISA. Individual clinician preference had an impact on premedication practices within each NNU. Conclusion: The wide variability on first-line premedication for endotracheal intubation noted in this survey could be overcome using best available evidence through consensus guidance driven by organisations such as British Association of Perinatal |Medicine (BAPM). Secondly, the divisive view around LISA premedication practices noted in this survey requires an answer through a randomised controlled trial. |
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MeSH term(s) | Infant, Newborn ; Humans ; Premedication/methods ; Surveys and Questionnaires ; Intubation, Intratracheal/methods ; Pulmonary Surfactants ; United Kingdom |
Chemical Substances | Pulmonary Surfactants |
Language | English |
Publishing date | 2023-06-15 |
Publishing country | Ireland |
Document type | Journal Article |
ZDB-ID | 752532-1 |
ISSN | 1872-6232 ; 0378-3782 |
ISSN (online) | 1872-6232 |
ISSN | 0378-3782 |
DOI | 10.1016/j.earlhumdev.2023.105808 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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