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  1. Article: Biodegradation of polyvinyl chloride by

    Nyamjav, Indra / Jang, Yejin / Lee, Ye Eun / Lee, Sukkyoo

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1175249

    Abstract: Polyvinyl chloride (PVC) is one of the widely used plastic products worldwide, and its accumulation in the natural environment has become a major global issue with regard to the environment and biotic health. There is accordingly strong demand for the ... ...

    Abstract Polyvinyl chloride (PVC) is one of the widely used plastic products worldwide, and its accumulation in the natural environment has become a major global issue with regard to the environment and biotic health. There is accordingly strong demand for the development of solutions and methods for environmental remediation. Degrading plastic waste using microorganisms is an effective and eco-friendly method. However, evidence of bacteria that afford efficient biodegradation of unplasticized, pure PVC film has yet to be reported. Therefore, the biodegradation of PVC becomes very important. Here, we present results on the physicochemical and structural studies of PVC by
    Language English
    Publishing date 2023-05-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1175249
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Antifungal Activity of Bulgarian Rose Damascena Oil against Vaginitis-Causing Opportunistic Fungi.

    Lee, Yejin / Park, Eunhye / Jang, Bohee / Hwang, Jisun / Lee, Jinmin / Oh, Eok-Soo

    Evidence-based complementary and alternative medicine : eCAM

    2023  Volume 2023, Page(s) 5054865

    Abstract: Since Bulgarian rose damascena oil is known for its anti-inflammatory, antioxidant, and antimicrobial properties, we investigated its antifungal activity against the species ... ...

    Abstract Since Bulgarian rose damascena oil is known for its anti-inflammatory, antioxidant, and antimicrobial properties, we investigated its antifungal activity against the species of
    Language English
    Publishing date 2023-12-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2023/5054865
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Chemical Constituents of the Flowers of

    Kim, Yejin / Kim, Jaeyoon / Son, So-Ri / Kim, Ji-Young / Choi, Jung-Hye / Jang, Dae Sik

    Plants (Basel, Switzerland)

    2022  Volume 11, Issue 13

    Abstract: The flower ... ...

    Abstract The flower of
    Language English
    Publishing date 2022-06-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants11131651
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Development of novel

    Jeon, Yangwon / Lee, Yejin / Kim, Yeonhong / Park, Chanhee / Choi, Hoon / Jang, Geupil / Yoon, Youngdae

    Frontiers in microbiology

    2022  Volume 13, Page(s) 1051926

    Abstract: Escherichia ... ...

    Abstract Escherichia coli
    Language English
    Publishing date 2022-12-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2022.1051926
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Physicochemical and Structural Evidence that

    Nyamjav, Indra / Jang, Yejin / Park, Nohyoon / Lee, Ye Eun / Lee, Sukkyoo

    Journal of polymers and the environment

    2023  , Page(s) 1–14

    Abstract: Biodegradation of plastic waste using microorganisms has been proposed as one of the solutions to the increasing worldwide plastic waste. Polypropylene (PP) is the second most used plastic used in various industries, and it has been widely used in the ... ...

    Abstract Biodegradation of plastic waste using microorganisms has been proposed as one of the solutions to the increasing worldwide plastic waste. Polypropylene (PP) is the second most used plastic used in various industries, and it has been widely used in the production of personal protective equipment such as masks due to the COVID-19 pandemic. Therefore, biodegradation of PP becomes very important. Here, we present results on the physicochemical and structural studies of PP biodegradation by
    Supplementary information: The online version contains supplementary material available at 10.1007/s10924-023-02878-y.
    Language English
    Publishing date 2023-05-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2017207-2
    ISSN 1572-8919 ; 1572-8900 ; 1566-2543
    ISSN (online) 1572-8919 ; 1572-8900
    ISSN 1566-2543
    DOI 10.1007/s10924-023-02878-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Design of Pb(II)-Specific

    Jeon, Yangwon / Lee, Yejin / Jang, Geupil / Kim, Bong-Gyu / Yoon, Youngdae

    Frontiers in microbiology

    2022  Volume 13, Page(s) 881050

    Abstract: Bacterial cell-based biosensors have been widely developed for detecting environmental toxic materials. ... ...

    Abstract Bacterial cell-based biosensors have been widely developed for detecting environmental toxic materials. The
    Language English
    Publishing date 2022-05-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2022.881050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Severe acute respiratory syndrome coronavirus 2 variants-Possibility of universal vaccine design: A review.

    Yoon, Eunhye / Kim, Dahyun / Jeon, Hyeeun / Kwon, Yejin / Jang, Yejin / Kim, Sulhee / Hwang, Kwang Yeon

    Computational and structural biotechnology journal

    2022  Volume 20, Page(s) 3533–3544

    Abstract: Both novel and conventional vaccination strategies have been implemented worldwide since the onset of coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite various medical advances in ...

    Abstract Both novel and conventional vaccination strategies have been implemented worldwide since the onset of coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite various medical advances in the treatment and prevention of the spread of this contagious disease, it remains a major public health threat with a high mortality rate. As several lethal SARS-CoV-2 variants continue to emerge, the development of several vaccines and medicines, each with certain advantages and disadvantages, is underway. Additionally, many modalities are at various stages of research and development or clinical trials. Here, we summarize emerging SARS-CoV-2 variants, including delta, omicron, and "stealth omicron," as well as available oral drugs for COVID-19. We also discuss possible antigen candidates other than the receptor-binding domain protein for the development of a universal COVID-19 vaccine. The present review will serve as a helpful resource for future vaccine and drug development to combat COVID-19.
    Language English
    Publishing date 2022-06-23
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2694435-2
    ISSN 2001-0370
    ISSN 2001-0370
    DOI 10.1016/j.csbj.2022.06.043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Identification of plastic-degrading bacteria in the human gut.

    Jang, Yejin / Nyamjav, Indra / Kim, Hong Rae / Suh, Dong-Eun / Park, Nohyoon / Lee, Ye Eun / Lee, Sukkyoo

    The Science of the total environment

    2024  , Page(s) 172775

    Abstract: Environmental pollution caused by the excessive use of plastics has resulted in the inflow of microplastics into the human body. However, the effects of microplastics on the human gut microbiota still need to be better understood. To determine whether ... ...

    Abstract Environmental pollution caused by the excessive use of plastics has resulted in the inflow of microplastics into the human body. However, the effects of microplastics on the human gut microbiota still need to be better understood. To determine whether plastic-degrading bacteria exist in the human gut, we collected the feces of six human individuals, did enrichment cultures and screened for bacterial species with a low-density polyethylene (LDPE) or polypropylene (PP)-degrading activity using a micro-spray method. We successfully isolated four bacterial species with an LDPE-degrading activity and three with a PP-degrading activity. Notably, all bacterial species identified with an LDPE or PP-degrading activity were opportunistic pathogens. We analyzed the microbial degradation of the LDPE or PP surface using scanning electron microscopy and confirmed that each bacterial species caused the physical changes. Chemical structural changes were further investigated using X-ray photoelectron spectroscopy and Fourier-transform-infrared spectroscopy, confirming the oxidation of the LDPE or PP surface with the formation of carbonyl groups (C=O), ester groups (CO), and hydroxyl groups (-OH) by each bacterial species. Finally, high temperature gel permeation chromatography (HT-GPC) analysis showed that these bacterial species performed to a limited extent depolymerization. These results indicate that, as a single species, these opportunistic pathogens in the human gut have a complete set of enzymes and other components required to initiate the oxidation of the carbon chains of LDPE or PP and to degrade them. Furthermore, these findings suggest that these bacterial species can potentially biodegrade and metabolize microplastics in the human gut.
    Language English
    Publishing date 2024-04-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2024.172775
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Discovery of antiviral SARS-CoV-2 main protease inhibitors by structure-guided hit-to-lead optimization of carmofur.

    Kang, Koon Mook / Jang, Yejin / Lee, Sang Soo / Jin, Mi Sun / Jun, Chang-Duk / Kim, Meehyein / Kim, Yong-Chul

    European journal of medicinal chemistry

    2023  Volume 260, Page(s) 115720

    Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease ( ... ...

    Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (M
    MeSH term(s) Humans ; SARS-CoV-2 ; COVID-19 ; Antiviral Agents/pharmacology ; Fluorouracil
    Chemical Substances 3C-like proteinase, SARS-CoV-2 (EC 3.4.22.-) ; Antiviral Agents ; Fluorouracil (U3P01618RT)
    Language English
    Publishing date 2023-08-18
    Publishing country France
    Document type Journal Article
    ZDB-ID 188597-2
    ISSN 1768-3254 ; 0009-4374 ; 0223-5234
    ISSN (online) 1768-3254
    ISSN 0009-4374 ; 0223-5234
    DOI 10.1016/j.ejmech.2023.115720
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Transcription Factor-Based Biosensors for Detecting Pathogens.

    Jeon, Yangwon / Lee, Yejin / Kim, Keugtae / Jang, Geupil / Yoon, Youngdae

    Biosensors

    2022  Volume 12, Issue 7

    Abstract: Microorganisms are omnipresent and inseparable from our life. Many of them are beneficial to humans, while some are not. Importantly, foods and beverages are susceptible to microbial contamination, with their toxins causing illnesses and even death in ... ...

    Abstract Microorganisms are omnipresent and inseparable from our life. Many of them are beneficial to humans, while some are not. Importantly, foods and beverages are susceptible to microbial contamination, with their toxins causing illnesses and even death in some cases. Therefore, monitoring and detecting harmful microorganisms are critical to ensuring human health and safety. For several decades, many methods have been developed to detect and monitor microorganisms and their toxicants. Conventionally, nucleic acid analysis and antibody-based analysis were used to detect pathogens. Additionally, diverse chromatographic methods were employed to detect toxins based on their chemical and structural properties. However, conventional techniques have several disadvantages concerning analysis time, sensitivity, and expense. With the advances in biotechnology, new approaches to detect pathogens and toxins have been reported to compensate for the disadvantages of conventional analysis from different research fields, including electrochemistry, nanotechnology, and molecular biology. Among them, we focused on the recent studies of transcription factor (TF)-based biosensors to detect microorganisms and discuss their perspectives and applications. Additionally, the other biosensors for detecting microorganisms reported in recent studies were also introduced in this review.
    MeSH term(s) Biosensing Techniques/methods ; Electrochemistry/methods ; Food Contamination ; Humans ; Nanotechnology/methods ; Toxins, Biological ; Transcription Factors
    Chemical Substances Toxins, Biological ; Transcription Factors
    Language English
    Publishing date 2022-06-29
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662125-3
    ISSN 2079-6374 ; 2079-6374
    ISSN (online) 2079-6374
    ISSN 2079-6374
    DOI 10.3390/bios12070470
    Database MEDical Literature Analysis and Retrieval System OnLINE

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