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Article ; Online: El iceberg de la discriminación en función del género en la medicina hospitalaria.

Arrizabalaga, Pilar / Doltra, Ada / Baranda, Lucía / Sebastià, M Carmen

2023 Volume 162, Issue 7, Page(s) 343–349

Title translation	The iceberg of discrimination based on gender in Hospital Medicine.
MeSH term(s)	Humans ; Hospital Medicine
Language	Spanish
Publishing date	2023-12-29
Publishing country	Spain
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	411607-0
ISSN	1578-8989 ; 0025-7753
ISSN (online)	1578-8989
ISSN	0025-7753
DOI	10.1016/j.medcli.2023.10.024
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Pattern of Consumption of Sports Supplements of Spanish Handball Players: Differences According to Gender and Competitive Level.

Romero-García, David / Martínez-Sanz, José Miguel / Sebastiá-Rico, Jaime / Manchado, Carmen / Vaquero-Cristóbal, Raquel

Nutrients

2024 Volume 16, Issue 2

Abstract: 1) Background: Given the physiological characteristics of handball, players may require the use of certain sports supplements (SS). However, very few studies have investigated the consumption of SS in handball. The aims were to determine the number of ... ...

Abstract	(1) Background: Given the physiological characteristics of handball, players may require the use of certain sports supplements (SS). However, very few studies have investigated the consumption of SS in handball. The aims were to determine the number of handball players who consume SS, to analyze their SS consumption pattern according to gender and competitive level, and to assess whether the SS they consume are supported by scientific evidence, and to which group they belong according to the classification of the Australian Institute of Sport (AIS). (2) Methods: A descriptive-correlational study was carried out on the habitual consumption of SS in 360 federated Spanish players by using a self-administered and validated questionnaire. (3) Results: These showed 65.8% of the sample consumed SS. According to the total number of participants, the most consumed supplements were from Group A: sports drinks (30.8%) and whey protein (30.4%). When analyzing the data by gender, the men's consumption was significantly higher for whey protein (
MeSH term(s)	Male ; Humans ; Creatine ; Whey Proteins ; Australia ; Sports/physiology ; Athletes
Chemical Substances	Creatine (MU72812GK0) ; Whey Proteins
Language	English
Publishing date	2024-01-20
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu16020315
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Considerations regarding the use of the sex/gender variable in research: moving towards good practice. Progenders decalogue.

Sugranyes, Gisela / Sebastià, M Carmen / García-Delgar, Blanca / Forcadel, Eduard / Coll-Vinent, Blanca

Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias

2023 Volume 35, Issue 4, Page(s) 303–305

Title translation	Consideraciones respecto al uso de la variable sexo/género en investigación para avanzar hacia una buena praxis: Decálogo PROGÉNEROS.
Language	English
Publishing date	2023-07-13
Publishing country	Spain
Document type	Journal Article
ZDB-ID	2127173-2
ISSN	2386-5857 ; 2386-5857
ISSN (online)	2386-5857
ISSN	2386-5857
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Article: O-RADS MRI scoring system: key points for correct application in inexperienced hands.

Cabedo, Lledó / Sebastià, Carmen / Munmany, Meritxell / Fusté, Pere / Gaba, Lydia / Saco, Adela / Rodriguez, Adela / Paño, Blanca / Nicolau, Carlos

Insights into imaging

2024 Volume 15, Issue 1, Page(s) 107

Abstract: Objectives: To evaluate the efficacy of the O-RADS MRI criteria in the stratification of risk of malignancy of solid or sonographically indeterminate ovarian masses and assess the interobserver agreement of this classification between experienced and ... ...

Abstract	Objectives: To evaluate the efficacy of the O-RADS MRI criteria in the stratification of risk of malignancy of solid or sonographically indeterminate ovarian masses and assess the interobserver agreement of this classification between experienced and inexperienced radiologists. Methods: This single-centre retrospective study included patients from 2019 to 2022 with sonographically indeterminate or solid ovarian masses who underwent MRI with a specific protocol for characterisation according to O-RADS MRI specifications. Each study was evaluated using O-RADS lexicon by two radiologists, one with 17 years of experience in gynaecological radiology and another with 4 years of experience in general radiology. Findings were classified as benign, borderline, or malignant according to histology or stability over time. Diagnostic performance and interobserver agreement were assessed. Results: A total of 183 patients with US indeterminate or solid adnexal masses were included. Fifty-seven (31%) did not have ovarian masses, classified as O-RADS 1. The diagnostic performance for scores 2-5 was excellent with a sensitivity, specificity, PPV, and NPV of 97.4%, 100%, 96.2%, and 100%, respectively by the experienced radiologist and 96.1%, 92.0%, 93.9%, and 94.8% by the inexperienced radiologist. Interobserver concordance was very high (Kappa index 0.92). Almost all the misclassified cases were due to misinterpretation of the classification similar to reports in the literature. Conclusion: The diagnostic performance of O-RADS MRI determined by either experienced or inexperienced radiologists is excellent, facilitating decision-making with high diagnostic accuracy and high reproducibility. Knowledge of this classification and use of assessment tools could avoid frequent errors due to misinterpretation. Critical relevance statement: Up to 31% of ovarian masses are considered indeterminate by transvaginal US and 32% of solid lesions considered malignant by transvaginal US are benign. The O-RADs MRI accurately classifies these masses, even when used by inexperienced radiologists, thereby avoiding incorrect surgical approaches. Key points: • O-RADS MRI accurately classifies indeterminate and solid ovarian masses by ultrasound. • There is excellent interobserver agreement between experienced and non-experienced radiologists. • O-RADS MRI is a helpful tool to assess clinical decision-making in ovarian tumours.
Language	English
Publishing date	2024-04-12
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2543323-4
ISSN	1869-4101
ISSN	1869-4101
DOI	10.1186/s13244-024-01670-3
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Article ; Online: Imaging Characterization of Renal Masses.

Nicolau, Carlos / Antunes, Natalie / Paño, Blanca / Sebastia, Carmen

Medicina (Kaunas, Lithuania)

2021 Volume 57, Issue 1

Abstract: The detection of a renal mass is a relatively frequent occurrence in the daily practice of any Radiology Department. The diagnostic approaches depend on whether the lesion is cystic or solid. Cystic lesions can be managed using the Bosniak classification, ...

Abstract	The detection of a renal mass is a relatively frequent occurrence in the daily practice of any Radiology Department. The diagnostic approaches depend on whether the lesion is cystic or solid. Cystic lesions can be managed using the Bosniak classification, while management of solid lesions depends on whether the lesion is well-defined or infiltrative. The approach to well-defined lesions focuses mainly on the differentiation between renal cancer and benign tumors such as angiomyolipoma (AML) and oncocytoma. Differential diagnosis of infiltrative lesions is wider, including primary and secondary malignancies and inflammatory disease, and knowledge of the patient history is essential. Radiologists may establish a possible differential diagnosis based on the imaging features of the renal masses and the clinical history. The aim of this review is to present the contribution of the different imaging techniques and image guided biopsies in the diagnostic management of cystic and solid renal lesions.
MeSH term(s)	Abscess/diagnostic imaging ; Adenoma/diagnostic imaging ; Adenoma, Oxyphilic/diagnostic imaging ; Angiomyolipoma/diagnostic imaging ; Carcinoma, Renal Cell/diagnostic imaging ; Carcinoma, Transitional Cell/diagnostic imaging ; Contrast Media ; Cysts/classification ; Cysts/diagnostic imaging ; Humans ; Kidney Diseases/diagnostic imaging ; Kidney Neoplasms/diagnostic imaging ; Leiomyoma/diagnostic imaging ; Lymphoma/diagnostic imaging ; Magnetic Resonance Imaging ; Plasmacytoma/diagnostic imaging ; Pyelonephritis/diagnostic imaging ; Pyelonephritis, Xanthogranulomatous/diagnostic imaging ; Tomography, X-Ray Computed ; Ultrasonography ; Ultrasonography, Doppler, Color
Chemical Substances	Contrast Media
Language	English
Publishing date	2021-01-08
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2188113-3
ISSN	1648-9144 ; 1010-660X
ISSN (online)	1648-9144
ISSN	1010-660X
DOI	10.3390/medicina57010051
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Article ; Online: Imaging Characterization of Renal Masses

Carlos Nicolau / Natalie Antunes / Blanca Paño / Carmen Sebastia

Medicina, Vol 57, Iss 51, p

2021 Volume 51

Abstract	The detection of a renal mass is a relatively frequent occurrence in the daily practice of any Radiology Department. The diagnostic approaches depend on whether the lesion is cystic or solid. Cystic lesions can be managed using the Bosniak classification, while management of solid lesions depends on whether the lesion is well-defined or infiltrative. The approach to well-defined lesions focuses mainly on the differentiation between renal cancer and benign tumors such as angiomyolipoma (AML) and oncocytoma. Differential diagnosis of infiltrative lesions is wider, including primary and secondary malignancies and inflammatory disease, and knowledge of the patient history is essential. Radiologists may establish a possible differential diagnosis based on the imaging features of the renal masses and the clinical history. The aim of this review is to present the contribution of the different imaging techniques and image guided biopsies in the diagnostic management of cystic and solid renal lesions.
Keywords	renal mass ; renal cyst ; renal cell carcinoma ; ultrasound ; computed tomography (CT) ; magnetic resonance imaging (MRI) ; Medicine (General) ; R5-920
Subject code	616
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Contrast media for hysterosalpingography: systematic search and review providing new guidelines by the Contrast Media Safety Committee of the European Society of Urogenital Radiology.

Geenen, Remy W F / van der Molen, Aart J / Dekkers, Ilona A / Bellin, Marie-France / Bertolotto, Michele / Correas, Jean-Michel / Heinz-Peer, Gertraud / Mahnken, Andreas H / Quattrocchi, Carlo C / Radbruch, Alexander / Reimer, Peter / Roditi, Giles / Sebastià, Carmen / Stacul, Fulvio / Romanini, Laura / Clément, Olivier / Brismar, Torkel B

European radiology

2024

Abstract: Objectives: Hysterosalpingography (HSG) is widely used for evaluating the fallopian tubes; however, controversies regarding the use of water- or oil-based iodine-based contrast media (CM) remain. The aim of this work was (1) to discuss reported ... ...

Abstract	Objectives: Hysterosalpingography (HSG) is widely used for evaluating the fallopian tubes; however, controversies regarding the use of water- or oil-based iodine-based contrast media (CM) remain. The aim of this work was (1) to discuss reported pregnancy rates related to the CM type used, (2) to validate the used CM in published literature, (3) to discuss possible complications and side effects of CM in HSG, and (4) to develop guidelines on the use of oil-based CM in HSG. Methods: A systematic literature search was conducted for original RCT studies or review/meta-analyses on using water-based and oil-based CM in HSG with fertility outcomes and complications. Nine randomized controlled trials (RCTs) and 10 reviews/meta-analyses were analyzed. Grading of the literature was performed based on the Oxford Centre for Evidence-Based Medicine (OCEBM) 2011 classification. Results: An approximately 10% higher pregnancy rate is reported for oil-based CM. Side effects are rare, but oil-based CM have potentially more side effects on the maternal thyroid function and the peritoneum. Conclusions: 1. HSG with oil-based CM gives approximately 10% higher pregnancy rates. 2. External validity is limited, as in five of nine RCTs, the CM used is no longer on the market. 3. Oil-based CM have potentially more side effects on the maternal thyroid function and on the peritoneum. 4. Guideline: Maternal thyroid function should be tested before HSG with oil-based CM and monitored for 6 months after. Clinical relevance statement: Oil-based CM is associated with an approximately 10% higher chance of pregnancy compared to water-based CM after HSG. Although side effects are rare, higher iodine concentration and slower clearance of oil-based CM may induce maternal thyroid function disturbance and peritoneal inflammation and granuloma formation. Key points: • It is unknown which type of contrast medium, oil-based or water-based, is the optimal for HSG. • Oil-based contrast media give a 10% higher chance of pregnancy after HSG, compared to water-based contrast media. • From the safety perspective, oil-based CM can cause thyroid dysfunction and an intra-abdominal inflammatory response in the patient.
Language	English
Publishing date	2024-04-04
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1085366-2
ISSN	1432-1084 ; 0938-7994 ; 1613-3749
ISSN (online)	1432-1084
ISSN	0938-7994 ; 1613-3749
DOI	10.1007/s00330-024-10707-6
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Article: Pilot Study for the Assessment of the Best Radiomic Features for Bosniak Cyst Classification Using Phantom and Radiologist Inter-Observer Selection.

Aymerich, María / Riveira-Martín, Mercedes / García-Baizán, Alejandra / González-Pena, Mariña / Sebastià, Carmen / López-Medina, Antonio / Mesa-Álvarez, Alicia / Tardágila de la Fuente, Gonzalo / Méndez-Castrillón, Marta / Berbel-Rodríguez, Andrea / Matos-Ugas, Alejandra C / Berenguer, Roberto / Sabater, Sebastià / Otero-García, Milagros

Diagnostics (Basel, Switzerland)

2023 Volume 13, Issue 8

Abstract: Since the Bosniak cysts classification is highly reader-dependent, automated tools based on radiomics could help in the diagnosis of the lesion. This study is an initial step in the search for radiomic features that may be good classifiers of benign- ... ...

Abstract	Since the Bosniak cysts classification is highly reader-dependent, automated tools based on radiomics could help in the diagnosis of the lesion. This study is an initial step in the search for radiomic features that may be good classifiers of benign-malignant Bosniak cysts in machine learning models. A CCR phantom was used through five CT scanners. Registration was performed with ARIA software, while Quibim Precision was used for feature extraction. R software was used for the statistical analysis. Robust radiomic features based on repeatability and reproducibility criteria were chosen. Excellent correlation criteria between different radiologists during lesion segmentation were imposed. With the selected features, their classification ability in benignity-malignity terms was assessed. From the phantom study, 25.3% of the features were robust. For the study of inter-observer correlation (ICC) in the segmentation of cystic masses, 82 subjects were prospectively selected, finding 48.4% of the features as excellent regarding concordance. Comparing both datasets, 12 features were established as repeatable, reproducible, and useful for the classification of Bosniak cysts and could serve as initial candidates for the elaboration of a classification model. With those features, the Linear Discriminant Analysis model classified the Bosniak cysts in terms of benignity or malignancy with 88.2% accuracy.
Language	English
Publishing date	2023-04-10
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662336-5
ISSN	2075-4418
ISSN	2075-4418
DOI	10.3390/diagnostics13081384
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Article: Active surveillance of small renal masses.

Sebastià, Carmen / Corominas, Daniel / Musquera, Mireia / Paño, Blanca / Ajami, Tarek / Nicolau, Carlos

Insights into imaging

2020 Volume 11, Issue 1, Page(s) 63

Abstract: Most renal masses incidentally detected by cross-sectional images are benign, being mainly cysts, and if they are malignant, they are indolent in nature with limited metastatic potential. Enhanced renal masses less than 4 cm in size are known as small ... ...

Abstract	Most renal masses incidentally detected by cross-sectional images are benign, being mainly cysts, and if they are malignant, they are indolent in nature with limited metastatic potential. Enhanced renal masses less than 4 cm in size are known as small renal masses (SRMs), and their growth rate (GR) and the possibility of developing metastasis are extremely low. Delayed intervention of SRMs by closed and routine imaging follow-up known as active surveillance (AS) is now an option according to urological guidelines. Radiologists have a key position in AS management of SRMs even unifocal and multifocal (sporadic or associated with genetic syndromes) and also in the follow-up of complex renal cysts by Bosniak cyst classification system. Radiologists play a key role in the AS of both unifocal and multifocal (sporadic or associated with genetic syndromes) SRMs as well as in the follow-up of complex renal cysts using the Bosniak cyst classification system. Indeed, radiologists must determine which patients with SRMs or complex renal cysts can be included in AS, establish the follow-up radiological test algorithm to be used in different scenarios, perform measurements in follow-up tests, and decide when AS should be discontinued. The purpose of this article is to review the indications and management of AS in SRMs, especially focused on specific scenarios, such as complex renal cysts and multifocal renal tumors (sporadic or hereditary). In this work, the authors aimed to provide a thorough review of imaging in the context of active surveillance of renal masses.
Language	English
Publishing date	2020-05-05
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	2543323-4
ISSN	1869-4101
ISSN	1869-4101
DOI	10.1186/s13244-020-00853-y
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Article: Perinatal post-mortem magnetic resonance imaging (MRI) of the central nervous system (CNS): a pictorial review.

Pérez-Serrano, Carlos / Bartolomé, Álvaro / Bargalló, Núria / Sebastià, Carmen / Nadal, Alfons / Gómez, Olga / Oleaga, Laura

Insights into imaging

2021 Volume 12, Issue 1, Page(s) 104

Abstract: Central nervous system (CNS) abnormalities cause approximately 32-37.7% of terminations of pregnancy (TOP). Autopsy is currently the gold standard for assessing dead foetuses and stillborn. However, it has limitations and is sometimes subject to parental ...

Abstract	Central nervous system (CNS) abnormalities cause approximately 32-37.7% of terminations of pregnancy (TOP). Autopsy is currently the gold standard for assessing dead foetuses and stillborn. However, it has limitations and is sometimes subject to parental rejection. Recent studies have described post-mortem foetal magnetic resonance imaging (MRI) as an alternative and even complementary to autopsy for CNS assessment. Radiologists now play a key role in the evaluation of perinatal deaths. Assessment of foetal CNS abnormalities is difficult, and interpretation of foetal studies requires familiarisation with normal and abnormal findings in post-mortem MRI studies as well as the strengths and limitations of the imaging studies. The purpose of this pictorial review is to report our experience in the post-mortem MRI evaluation of the CNS system, including a description of the protocol used, normal CNS findings related to post-mortem status, abnormal CNS findings in our sample, and the correlation of these findings with histopathological results.
Language	English
Publishing date	2021-07-22
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	2543323-4
ISSN	1869-4101
ISSN	1869-4101
DOI	10.1186/s13244-021-01051-0
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