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Article ; Online: Imaging Methods of Joint Damage in Early Rheumatoid Arthritis.

Sizova, Lyudmila

Current rheumatology reviews

2015 Volume 11, Issue 1, Page(s) 64–67

Abstract: Rheumatoid arthritis (RA) is an autoimmune connective tissue disease of unknown etiology with development of persistent and erosive arthritis ultimately resulting in disability. The prevalence of RA is about 0.5-1% in adults worldwide. Radiographic ... ...

Abstract	Rheumatoid arthritis (RA) is an autoimmune connective tissue disease of unknown etiology with development of persistent and erosive arthritis ultimately resulting in disability. The prevalence of RA is about 0.5-1% in adults worldwide. Radiographic changes in the joints at early stages of the disease are often absent. Accordingly, there is a need for instrumental methods of diagnosis with greater sensitivity. These include magnetic resonance imaging and ultrasound of joints. The paper reviews the instrumental methods of diagnosis of joint damage in early RA according to the existing literature of PubMed database. Selection criteria were original articles in the English language reporting «X-ray», «MRI» and «ultrasound» in patients with early RA.
Language	English
Publishing date	2015
Publishing country	United Arab Emirates
Document type	Journal Article
ISSN	1875-6360
ISSN (online)	1875-6360
DOI	10.2174/1573397111666150522094405
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Article ; Online: Diagnostic value of antibodies to modified citrullinated vimentin in early rheumatoid arthritis.

Sizova, Lyudmila

Human immunology

2012 Volume 73, Issue 4, Page(s) 389–392

Abstract: The aim of this study was to evaluate the usefulness of antibodies to modified citrullinated vimentin (anti-MCV) for diagnosing early rheumatoid arthritis (RA) and to examine the correlations between anti-MCV and clinical parameters as well as ... ...

Abstract	The aim of this study was to evaluate the usefulness of antibodies to modified citrullinated vimentin (anti-MCV) for diagnosing early rheumatoid arthritis (RA) and to examine the correlations between anti-MCV and clinical parameters as well as radiographic and ultrasound data. Our results suggest that anti-MCV has a sensitivity and specificity of 53.3 and 83.3%, respectively, and a positive prognostic value of 96% in patients with early RA. Anti-MCV antibodies were observed in 48.5% of rheumatoid factor (RF)-negative RA patients in data from a latex test and in 35.7% of patients with negative results for immunoglobulin (Ig)-M-RF. The positive result for both anti-MCV and IgM-RF has a sensitivity of 42.2% and a specificity of 100%. No significant correlation was observed between anti-MCV and disease activity score using 28 joint counts, radiographic RA stage, number of erosions on ultrasonography of joints, and quality-of-life scores at disease onset. The Spearman correlation was significant in early RA patients with positive results of anti-MCV between the titers of this marker and arthritis duration, level of erythrocyte sedimentation rate, and IgM-RF. The best diagnostic strategy in early RA may be to assay both anti-MCV and IgM-RF. Thus, a question arises regarding the possible inclusion of anti-MCV in future revisions of the classification criteria of RA.
MeSH term(s)	Antibodies/blood ; Antibodies/immunology ; Arthritis, Rheumatoid/diagnosis ; Arthritis, Rheumatoid/immunology ; Autoantibodies/blood ; Autoantibodies/immunology ; Female ; Humans ; Male ; Middle Aged ; Rheumatoid Factor/blood ; Sensitivity and Specificity ; Vimentin/chemistry ; Vimentin/immunology
Chemical Substances	Antibodies ; Autoantibodies ; Vimentin ; Rheumatoid Factor (9009-79-4)
Language	English
Publishing date	2012-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	801524-7
ISSN	1879-1166 ; 0198-8859
ISSN (online)	1879-1166
ISSN	0198-8859
DOI	10.1016/j.humimm.2012.01.007
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Article ; Online: Treatment of early arthritis using arthrofoon (ultra-low doses of antibodies to tumor necrosis factor-α).

Sizova, Lyudmila V

Indian journal of pharmacology

2011 Volume 43, Issue 6, Page(s) 724–725

Abstract: The main aim of treatment of early rheumatoid arthritis (RA) should be to achieve clinical remission to prevent structural damage and physical disability. Arthrofoon modifies production/activity of endogenous inhibitors of tumor necrosis factor-α (TNF-α). ...

Abstract	The main aim of treatment of early rheumatoid arthritis (RA) should be to achieve clinical remission to prevent structural damage and physical disability. Arthrofoon modifies production/activity of endogenous inhibitors of tumor necrosis factor-α (TNF-α). The sublingual rout is the most acceptable to ambulatory treatment because it does not produce the adverse reactions associated with intravenous therapy. The treatment with arthrofoon in outpatient with early RA is analyzed here. This report is devoted to the 28-year-old Russian woman who received arthrofoon due to suspicion of early RA. The strategy of early prescription of ultra-low doses of TNF-α antibody within two years was confirmed by the clinical improvement and delay of radiological disease progression in patient with undifferentiated arthritis or probable RA initially.
Language	English
Publishing date	2011-12-05
Publishing country	India
Document type	Journal Article
ZDB-ID	605829-2
ISSN	1998-3751 ; 0253-7613
ISSN (online)	1998-3751
ISSN	0253-7613
DOI	10.4103/0253-7613.89836
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Article ; Online: Approaches to the treatment of early rheumatoid arthritis with disease-modifying antirheumatic drugs.

Sizova, Lyudmila

British journal of clinical pharmacology

2008 Volume 66, Issue 2, Page(s) 173–178

Abstract: This paper reviews recent approaches to treatment of early rheumatoid arthritis (RA) with disease-modifying antirheumatic drugs (DMARDs). The literature on treatment the early RA published between 1995 and 2007 was accessed through the PubMed database ... ...

Abstract	This paper reviews recent approaches to treatment of early rheumatoid arthritis (RA) with disease-modifying antirheumatic drugs (DMARDs). The literature on treatment the early RA published between 1995 and 2007 was accessed through the PubMed database from the National Library of Medicine. Keywords were 'early rheumatoid arthritis', 'disease-modifying antirheumatic drugs', 'biologic agents' and 'combination therapy'. Only results of trials on human subjects that directly measured the effects of DMARDs or biological agents on clinical, laboratory parameters and radiological progression of early RA were selected. Combination therapy suppresses RA activity and radiological progression more effectively than monotherapy. If better control of RA is evident after 3-6 months of treatment with the combination of DMARDs, one must still decide whether to stop the first DMARD, stop the second, or continue with the combination. Combination therapy biological agents (infliximab, adalimumab) with methotrexate and etanercept therapy alone may induce remission in many patients with early RA. It is a method of choice in patients with an adverse prognosis. The main indications for combination therapy 'standard' DMARDs or combination 1 DMARDs with a biological agent are such variables as detection of a shared epitope, increase of concentration of anticyclic citrullinated peptide antibodies, rheumatoid factor, C-reactive protein, 28-joint disease activity score, Sharp score and presence of erosion in joints. The majority of rheumatologists believe that patients with RA should be treated with DMARDs earlier rather than later in the disease process. Further trials should establish the optimal approaches to early RA therapy.
MeSH term(s)	Antibodies, Monoclonal/therapeutic use ; Antirheumatic Agents/administration & dosage ; Arthritis, Rheumatoid/drug therapy ; Arthritis, Rheumatoid/psychology ; Clinical Trials as Topic ; Disease Progression ; Drug Therapy, Combination ; Humans ; Infliximab ; Isoxazoles/therapeutic use ; Leflunomide ; Methotrexate/therapeutic use ; Quality of Life/psychology ; Severity of Illness Index ; Sulfasalazine/therapeutic use ; Time Factors ; Treatment Outcome ; Tumor Necrosis Factor-alpha/antagonists & inhibitors
Chemical Substances	Antibodies, Monoclonal ; Antirheumatic Agents ; Isoxazoles ; Tumor Necrosis Factor-alpha ; Sulfasalazine (3XC8GUZ6CB) ; Infliximab (B72HH48FLU) ; Leflunomide (G162GK9U4W) ; Methotrexate (YL5FZ2Y5U1)
Language	English
Publishing date	2008-05-15
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	188974-6
ISSN	1365-2125 ; 0306-5251 ; 0264-3774
ISSN (online)	1365-2125
ISSN	0306-5251 ; 0264-3774
DOI	10.1111/j.1365-2125.2008.03222.x
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Article ; Online: Treatment of early arthritis using arthrofoon (ultra-low doses of antibodies to tumor necrosis factor-α)

Lyudmila V Sizova

Indian Journal of Pharmacology, Vol 43, Iss 6, Pp 724-

2011 Volume 725

Abstract	The main aim of treatment of early rheumatoid arthritis (RA) should be to achieve clinical remission to prevent structural damage and physical disability. Arthrofoon modifies production/activity of endogenous inhibitors of tumor necrosis factor-α (TNF-α). The sublingual rout is the most acceptable to ambulatory treatment because it does not produce the adverse reactions associated with intravenous therapy. The treatment with arthrofoon in outpatient with early RA is analyzed here. This report is devoted to the 28-year-old Russian woman who received arthrofoon due to suspicion of early RA. The strategy of early prescription of ultra-low doses of TNF-α antibody within two years was confirmed by the clinical improvement and delay of radiological disease progression in patient with undifferentiated arthritis or probable RA initially.
Keywords	Arthrofoon ; early arthritis ; undifferentiated arthritis ; Therapeutics. Pharmacology ; RM1-950 ; Medicine ; R
Language	English
Publishing date	2011-01-01T00:00:00Z
Publisher	Medknow Publications
Document type	Article ; Online
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Article ; Online: Assessment of the toxicity of silicon nanooxide in relation to various components of the agroecosystem under the conditions of the model experiment.

Lebedev, Svyatoslav Valeryevich / Gavrish, Irina Aleksandrovna / Galaktionova, Lyudmila Vyacheslavovna / Korotkova, Anastasia Mickhailovna / Sizova, Elena Anatolyevna

Environmental geochemistry and health

2018 Volume 41, Issue 2, Page(s) 769–782

Abstract: Investigation of ... ...

Abstract	Investigation of SiO
MeSH term(s)	Animals ; Biomass ; Catalase/metabolism ; Nanoparticles ; Oligochaeta/drug effects ; Silicon Dioxide/toxicity ; Soil/chemistry ; Soil Pollutants/analysis ; Superoxide Dismutase/metabolism ; Triticum/metabolism
Chemical Substances	Soil ; Soil Pollutants ; Silicon Dioxide (7631-86-9) ; Catalase (EC 1.11.1.6) ; Superoxide Dismutase (EC 1.15.1.1)
Language	English
Publishing date	2018-08-18
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	52039-1
ISSN	1573-2983 ; 0142-7245 ; 0269-4042
ISSN (online)	1573-2983
ISSN	0142-7245 ; 0269-4042
DOI	10.1007/s10653-018-0171-3
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Zs.A 4723: Show issues

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Article ; Online: Impact of molybdenum nanoparticles on survival, activity of enzymes, and chemical elements in Eisenia fetida using test on artificial substrata.

Lebedev, Sviatoslav / Yausheva, Elena / Galaktionova, Lyudmila / Sizova, Elena

Environmental science and pollution research international

2016 Volume 23, Issue 18, Page(s) 18099–18110

Abstract: The influence of molybdenum oxide nanoparticles (MoO3) on the growth and survival of Eisenia fetida was established. The activity of antioxidant enzymes and changes in concentration of molybdenum in the body of E. fetida were determined. The degree of ... ...

Abstract	The influence of molybdenum oxide nanoparticles (MoO3) on the growth and survival of Eisenia fetida was established. The activity of antioxidant enzymes and changes in concentration of molybdenum in the body of E. fetida were determined. The degree of bacterial bioluminescence inhibition in extracts of substrates and worm was studied using luminescent strain Escherichia coli K12 TG1. The enzymatic activity of substrates before and after exposure with nanoparticles and worms was assessed. Nanoparticles have concentrations of 10, 40, and 500 mg/kg of dry matter, and substrata are made of artificial soil (substrate A) and microcrystalline cellulose (substrate B). Spherical nanoparticles MoO3, yellow in color, with size 92 ± 0.3 nm, Z-potential 42 ± 0.52 mV, molybdenum content 99.8 mass/%, and specific area 12 m(2)/g were used in the study. A significant decrease by 23.3 % in weight was registered (for MoO3 NPs at 500 mg/kg) on substrate A (p ≤ 0.05). On substrate B, the maximum decrease in weight by 20.5, 33.3, and 16.9 % (p ≤ 0.05) was registered at a dose of 10, 40, and 500 mg/kg, respectively; mortality was from 6.6 to 73 %. After the assessment of bacterial bioluminescence inhibition in substrates A and B (extracts) and before worms were put, the toxicity of substrates was established at doses of 40 and 500 mg/kg, expressed in inhibitory concentration (IC) 30 and IC 50 values. Comparatively, on days 7 and 14, after exposure in the presence of E. fetida, no inhibition of bioluminescence was registered in extracts of substrates A and B, indicating the reduction in toxicity of substrates. The initial content of molybdenum in E. fetida was 0.9 ± 0.018 mg/kg of dry matter. The degree of molybdenum accumulation in worm tissue was dependent on the dose and substrate quality. In particular, 2-7 mg/kg of molybdenum accumulated from substrate A, while up to 15 kg/kg of molybdenum accumulated from substrate B (day 7). Molybdenum concentration decreased by 64.8 and 57.4 % at doses 40 and 500 mg/kg, respectively, on day 14. The reaction of antioxidant enzymes was shown in an insignificant increase of glutathione reductase (GSR) and catalase (CAT) at concentrations of 10 and 40 mg/kg in substrate A, followed by the subsequent reduction of their activity at the dose of 500 mg/kg MoO3. The activity of GSR in substrate B against the presence of MoO3 nanoparticles decreased, with significant difference of 33.5 % (p ≤ 0.05) at the dose of 500 mg/kg compared with untreated soil. In experiments with substrate A, an increase of catalase activity was registered for the control sample. The presence of MoO3 nanoparticles at the concentration of 10 mg/kg in the environment promoted enzymatic activity on days 7 and 14, respectively. A further increase of nanoparticle concentration resulted in the decrease of catalase activity with a minimum value at the concentration of MoO3 of 500 mg/kg. In the experiment with substrate B at the concentration of MoO3 nanoparticles of 40 mg/kg, enzymatic activity increases on day 7 of exposure. However, the stimulating effect of nanoparticles stops by day 14 of the experiment and further catalase activity is dose dependent with the smallest value in the experiment with MoO3 having the concentration of 500 mg/kg.
MeSH term(s)	Animals ; Antioxidants/metabolism ; Catalase/metabolism ; Escherichia coli K12 ; Molybdenum/toxicity ; Nanoparticles/toxicity ; Oligochaeta/drug effects ; Oligochaeta/enzymology ; Oligochaeta/growth & development ; Oxidation-Reduction ; Oxides/toxicity ; Soil ; Soil Pollutants/toxicity ; Superoxide Dismutase/metabolism ; Toxicity Tests
Chemical Substances	Antioxidants ; Oxides ; Soil ; Soil Pollutants ; molybdenum trioxide (22FQ3F03YS) ; Molybdenum (81AH48963U) ; Catalase (EC 1.11.1.6) ; Superoxide Dismutase (EC 1.15.1.1)
Language	English
Publishing date	2016-09
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-016-6916-6
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Article ; Online: A fluorescent microspheres-based microfluidic test system for the detection of immunoglobulin G to SARS-CoV-2

Ruslan I. Shakurov / Yaroslav D. Shansky / Kirill A. Prusakov / Svetlana V. Sizova / Stepan P. Dudik / Lyudmila V. Plotnikova / Valentin A. Manuvera / Dmitry V. Klinov / Vassili N. Lazarev / Julia A. Bespyatykh / Dmitriy V. Basmanov

Клиническая практика, Vol 14, Iss 1, Pp 44-

2023 Volume 53

Abstract: Background: The pandemic of the new coronavirus infection, COVID-19, is currently ongoing in the world. Over the years, the pathogen, SARS-CoV-2, has undergone a series of mutational genome changes, which has led to the spread of various genetic variants ...

Abstract	Background: The pandemic of the new coronavirus infection, COVID-19, is currently ongoing in the world. Over the years, the pathogen, SARS-CoV-2, has undergone a series of mutational genome changes, which has led to the spread of various genetic variants of the virus. Meanwhile, the methods used to diagnose SARS-CoV-2, to establish the disease stage and to assess the immunity, are nonspecific to SARS-CoV-2 variants and time-consumable. Thus, the development of new methods for diagnosing COVID-19, as well as their implementation in practice, is currently an important direction. In particular, application of systems based on chemically modified fluorescent microspheres (with a multiplex assay for target protein molecules) opens great opportunities. Aim: development of a microfluidic diagnostic test system based on fluorescent microspheres for the specific detection of immunoglobulins G (IgG) to SARS-CoV-2. Methods: A collection of human serum samples was characterized using enzyme-linked immunosorbent assay (ELISA) and commercially available reagent kits. IgG to SARS-CoV-2 in the human serum were detected by the developed immunofluorescent method using microspheres containing the chemically immobilized RBD fragment of the SARS-CoV-2 (Kappa variant) viral S-protein. Results: The level of IgG in the blood serum of recovered volunteers was 9-300 times higher than that in apparently healthy volunteers, according to ELISA (p0.001). Conjugates of fluorescent microspheres with the RBD-fragment of the S-protein, capable of specifically binding IgG from the blood serum, have been obtained. The immune complexes formation was confirmed by the fluorescence microscopy data; the fluorescence intensity of secondary antibodies in the immune complexes formed on the surface of microspheres was proportional to the content of IgG (r 0.963). The test system had a good predictive value (AUC 70.3%). Conclusion: A test system has been developed, based on fluorescent microspheres containing the immobilized RBD fragment of the SARS-CoV-2 ...
Keywords	enzyme-linked immunosorbent assay ; elisa ; covid-19 testing ; personalized medicine ; Medicine ; R
Subject code	600
Language	English
Publishing date	2023-04-01T00:00:00Z
Publisher	Eco-vector
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Impact of molybdenum nanoparticles on survival, activity of enzymes, and chemical elements in Eisenia fetida using test on artificial substrata

Lebedev, Sviatoslav / Elena Sizova / Elena Yausheva / Lyudmila Galaktionova

Environmental science and pollution research international. 2016 Sept., v. 23, no. 18

2016

Abstract: The influence of molybdenum oxide nanoparticles (MoOâ) on the growth and survival of Eisenia fetida was established. The activity of antioxidant enzymes and changes in concentration of molybdenum in the body of E. fetida were determined. The degree of ... ...

Abstract	The influence of molybdenum oxide nanoparticles (MoOâ) on the growth and survival of Eisenia fetida was established. The activity of antioxidant enzymes and changes in concentration of molybdenum in the body of E. fetida were determined. The degree of bacterial bioluminescence inhibition in extracts of substrates and worm was studied using luminescent strain Escherichia coli K12 TG1. The enzymatic activity of substrates before and after exposure with nanoparticles and worms was assessed. Nanoparticles have concentrations of 10, 40, and 500Â mg/kg of dry matter, and substrata are made of artificial soil (substrate A) and microcrystalline cellulose (substrate B). Spherical nanoparticles MoOâ, yellow in color, with size 92âÂ±â0.3Â nm, Z-potential 42âÂ±â0.52Â mV, molybdenum content 99.8 mass/%, and specific area 12Â mÂ²/g were used in the study. A significant decrease by 23.3Â % in weight was registered (for MoOâ NPs at 500Â mg/kg) on substrate A (pââ¤â0.05). On substrate B, the maximum decrease in weight by 20.5, 33.3, and 16.9Â % (pââ¤â0.05) was registered at a dose of 10, 40, and 500Â mg/kg, respectively; mortality was from 6.6 to 73Â %. After the assessment of bacterial bioluminescence inhibition in substrates A and B (extracts) and before worms were put, the toxicity of substrates was established at doses of 40 and 500Â mg/kg, expressed in inhibitory concentration (IC) 30 and IC 50 values. Comparatively, on days 7 and 14, after exposure in the presence of E. fetida, no inhibition of bioluminescence was registered in extracts of substrates A and B, indicating the reduction in toxicity of substrates. The initial content of molybdenum in E. fetida was 0.9âÂ±â0.018Â mg/kg of dry matter. The degree of molybdenum accumulation in worm tissue was dependent on the dose and substrate quality. In particular, 2â7Â mg/kg of molybdenum accumulated from substrate A, while up to 15Â kg/kg of molybdenum accumulated from substrate B (day 7). Molybdenum concentration decreased by 64.8 and 57.4Â % at doses 40 and 500Â mg/kg, respectively, on day 14. The reaction of antioxidant enzymes was shown in an insignificant increase of glutathione reductase (GSR) and catalase (CAT) at concentrations of 10 and 40Â mg/kg in substrate A, followed by the subsequent reduction of their activity at the dose of 500Â mg/kg MoOâ. The activity of GSR in substrate B against the presence of MoOâ nanoparticles decreased, with significant difference of 33.5Â % (pââ¤â0.05) at the dose of 500Â mg/kg compared with untreated soil. In experiments with substrate A, an increase of catalase activity was registered for the control sample. The presence of MoOâ nanoparticles at the concentration of 10Â mg/kg in the environment promoted enzymatic activity on days 7 and 14, respectively. A further increase of nanoparticle concentration resulted in the decrease of catalase activity with a minimum value at the concentration of MoOâ of 500Â mg/kg. In the experiment with substrate B at the concentration of MoOâ nanoparticles of 40Â mg/kg, enzymatic activity increases on day 7 of exposure. However, the stimulating effect of nanoparticles stops by day 14 of the experiment and further catalase activity is dose dependent with the smallest value in the experiment with MoOâ having the concentration of 500Â mg/kg.
Keywords	antioxidants ; bioluminescence ; catalase ; cellulose ; color ; dose response ; Eisenia fetida ; enzyme activity ; Escherichia coli K12 ; glutathione-disulfide reductase ; inhibitory concentration 50 ; molybdenum ; mortality ; nanoparticles ; soil ; toxicity
Language	English
Dates of publication	2016-09
Size	p. 18099-18110.
Publishing place	Springer Berlin Heidelberg
Document type	Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-016-6916-6
Database	NAL-Catalogue (AGRICOLA)

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Article: Assessment of the toxicity of silicon nanooxide in relation to various components of the agroecosystem under the conditions of the model experiment

Lebedev, Svyatoslav Valeryevich / Galaktionova, Lyudmila Vyacheslavovna / Gavrish, Irina Aleksandrovna / Korotkova, Anastasia Mickhailovna / Sizova, Elena Anatolyevna

Environmental geochemistry and health. 2019 Apr., v. 41, no. 2

2019

Abstract: Investigation of SiO2 nanoparticles (NPs) effect on Eisenia fetida showed no toxic effect of the metal at a concentration of 250, 500 and 1000 mg per kg of soil, but conversely, a biomass increase from 23.5 to 29.5% (at the protein level decrease from 60 ...

Abstract	Investigation of SiO2 nanoparticles (NPs) effect on Eisenia fetida showed no toxic effect of the metal at a concentration of 250, 500 and 1000 mg per kg of soil, but conversely, a biomass increase from 23.5 to 29.5% (at the protein level decrease from 60 to 80%). The reaction of the earthworm organism fermentative system was expressed in the decrease in the level of superoxide dismutase (SOD) on the 14th day and in the increase in its activity to 27% on the 28th day. The catalase level (CAT) showed low activity at average element concentrations and increase by 39.4% at a dose of 1000 mg/kg. Depression of malonic dialdehyde (MDA) was established at average concentrations of 11.2% and level increase up to 9.1% at a dose of 1000 mg/kg with the prolongation of the effect up to 87.5% after 28-day exposure. The change in the microbiocenosis of the earthworm intestine was manifested by a decrease in the number of ammonifiers (by 42.01–78.9%), as well as in the number of amylolytic microorganisms (by 31.7–65.8%). When the dose of SiO2 NPs increased from 100 to 1000 mg/kg, the number of Azotobacter increased (by 8.2–22.2%), while the number of cellulose-destroying microorganisms decreased to 71.4% at a maximum dose of 1000 mg/kg. The effect of SiO2 NPs on Triticum aestivum L. was noted in the form of a slight suppression of seed germination (no more than 25%), an increase in the length of roots and aerial organs which generally resulted in an increase in plant biomass. Assessing the soil microorganisms’ complex during introduction of metal into the germination medium of Triticum aestivum L., there was noted a decrease in the ammonifiers number (by 4.7–67.6%) with a maximum value at a dose of 1000 mg/kg. The number of microorganisms using mineral nitrogen decreased by 29.5–69.5% with a simultaneous increase in the number at a dose of 50 mg/kg (+ 20%). Depending on NP dose, there was an inhibition of the microscopic fungi development by 18.1–72.7% and an increase in the number of cellulose-destroying microorganisms. For all variants of the experiment, the activity of soil enzymes of the hydrolase and oxidoreductase classes was decreased.
Keywords	agroecosystems ; Azotobacter ; catalase ; earthworms ; Eisenia fetida ; fungi ; germination ; hydrolases ; intestines ; models ; nanoparticles ; nitrogen ; phytomass ; protein content ; roots ; silica ; silicon ; soil ; soil enzymes ; soil microorganisms ; superoxide dismutase ; toxicity ; Triticum aestivum
Language	English
Dates of publication	2019-04
Size	p. 769-782.
Publishing place	Springer Netherlands
Document type	Article
ZDB-ID	52039-1
ISSN	1573-2983 ; 0142-7245 ; 0269-4042
ISSN (online)	1573-2983
ISSN	0142-7245 ; 0269-4042
DOI	10.1007/s10653-018-0171-3
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In stock of ZB MED Bonn / Germany

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Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED