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  1. Article ; Online: Challenges in Diagnosis and Treatment of

    Pınarlık, Fatihan / Keske, Şiran / Rozanes, İzzet / Ergönül, Önder

    Infectious diseases & clinical microbiology

    2023  Volume 5, Issue 1, Page(s) 49–52

    Abstract: A 57-year-old female patient presented with fever, nausea, vomiting, loss of appetite, and weight loss within the last two months. Ceftriaxone and metronidazole therapy was started upon discovery of a liver abscess but provided no benefit. Following the ... ...

    Abstract A 57-year-old female patient presented with fever, nausea, vomiting, loss of appetite, and weight loss within the last two months. Ceftriaxone and metronidazole therapy was started upon discovery of a liver abscess but provided no benefit. Following the of abscess biopsy, the patient developed fever, itching, anemia, acute renal failure, hyperbilirubinemia, and eosinophilia that required intensive care unit (ICU) admission. The
    Language English
    Publishing date 2023-03-11
    Publishing country Turkey
    Document type Case Reports
    ISSN 2667-646X
    ISSN (online) 2667-646X
    DOI 10.36519/idcm.2023.197
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Alarming increase in fluoroquinolone resistance among non-typhoidal salmonella isolates.

    Beşli, Yeşim / Keske, Şiran / Dikenelli, Bilge E / Palaoğlu, K Erhan / Ergönül, Önder

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

    2024  

    Language English
    Publishing date 2024-03-09
    Publishing country England
    Document type Letter
    ZDB-ID 1328418-6
    ISSN 1469-0691 ; 1470-9465 ; 1198-743X
    ISSN (online) 1469-0691
    ISSN 1470-9465 ; 1198-743X
    DOI 10.1016/j.cmi.2024.03.010
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4541: Show issues Location:
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    Zs.MO 284: Show issues

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  3. Article ; Online: Discrepancy between IDSA and ESGBOR in Lyme disease: Individual participant meta-analysis in Türkiye.

    Yıldız, Abdullah Burak / Çetin, Ecesu / Pınarlık, Fatihan / Keske, Şiran / Can, Füsun / Ergönül, Önder

    Zoonoses and public health

    2024  

    Abstract: Background: The evidence on the prevalence of Lyme borreliosis (LB) is limited, but there is a suspicion of overdiagnosis of LB in recent years. We reviewed the LB diagnosis and treatment-related data in Türkiye, based on the Infectious Diseases Society ...

    Abstract Background: The evidence on the prevalence of Lyme borreliosis (LB) is limited, but there is a suspicion of overdiagnosis of LB in recent years. We reviewed the LB diagnosis and treatment-related data in Türkiye, based on the Infectious Diseases Society of America (IDSA) 2020 and European Society of Clinical Microbiology and Infectious Diseases Study Group for Lyme Borreliosis (ESGBOR) 2018 guidelines. By detecting the disagreements between these two, we outlined the areas to be improved for future guidelines.
    Methods: We performed a literature search according to the PRISMA guidelines in PubMed, Ovid-Medline, Web of Science, Turkish Medline, Scopus, CINAHL, ULAKBIM TR Index, Google Scholar and Cochrane Library databases. We included the published cases in a database and evaluated according to IDSA and ESGBOR guidelines. We outlined the reasons for misdiagnoses and inappropriate uses of antibiotics.
    Results: We included 42 relevant studies with 84 LB cases reported from Türkiye between 1990 and December 2022. Among 84 cases, the most common clinical findings were nervous system findings (n = 37, 44.0%), erythema migrans (n = 29, 34.5%) and ophthalmologic findings (n = 15, 17.9%). The IDSA 2020 and ESGBOR 2018 guidelines agreed on the diagnosis of 71 (84.5%) cases; there was an agreement that 31 cases (36.9%) were misdiagnosed and 40 cases (47.6%) were correctly diagnosed, and there was disagreement for 13 cases (15.5%). Serum immunoglobulin M (IgM), IgG measurements by ELISA and western blot were widely performed, and they were effective in definitive diagnosis merely when used according to guidelines. Inappropriate use of antibiotics was detected in 42 (50.0%) of cases which were classified in the following categories: incorrect LB diagnosis, inappropriate choice of antibiotic, inappropriate route of drug administration and prolonged antibiotic treatment.
    Conclusion: Overdiagnosis and non-adherence to guidelines is a common problem. The discordance between seroprevalence and clinical studies necessitates a consensus over the best clinical approach.
    Language English
    Publishing date 2024-02-27
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2271118-1
    ISSN 1863-2378 ; 1863-1959
    ISSN (online) 1863-2378
    ISSN 1863-1959
    DOI 10.1111/zph.13119
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Approach to Fever in the Returning Traveler.

    Ergönül, Önder / Keske, Şiran

    The New England journal of medicine

    2017  Volume 376, Issue 18, Page(s) 1797

    MeSH term(s) Fever ; Humans ; Travel
    Keywords covid19
    Language English
    Publishing date 2017--04
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc1703009
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  6. Article ; Online: The Practice of Antimicrobial Stewardship in Thoracic Surgery and its Effectiveness.

    Madran, Bahar / Keske, Şiran / Tanju, Serhan / Cesur, Ekin Ezgi / Pala, Selin / Dilege, Şükrü / Ergönül, Önder

    Infectious diseases & clinical microbiology

    2024  Volume 6, Issue 1, Page(s) 60–65

    Abstract: This study examines the effects of the bundle of antimicrobial stewardship measures for prophylactic antibiotics among thoracic surgery patients. A local protocol, based on current guidelines starting from December 2014, was developed by the Infection ... ...

    Abstract This study examines the effects of the bundle of antimicrobial stewardship measures for prophylactic antibiotics among thoracic surgery patients. A local protocol, based on current guidelines starting from December 2014, was developed by the Infection Control and Thoracic Surgery Teams. The effects of this protocol were assessed by monitoring a total of 1380 patients before and after its implementation from January 1, 2011, to December 31, 2022.
    Language English
    Publishing date 2024-03-08
    Publishing country Turkey
    Document type Journal Article
    ISSN 2667-646X
    ISSN (online) 2667-646X
    DOI 10.36519/idcm.2024.301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: What is the 'new normal' in surgical procedures in the era of COVID-19?

    Cimen, Cansu / Keske, Şiran / Ergönül, Önder

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

    2020  Volume 27, Issue 1, Page(s) 16–18

    MeSH term(s) COVID-19/diagnosis ; COVID-19/prevention & control ; COVID-19 Testing/methods ; Elective Surgical Procedures/methods ; Humans ; Mass Screening ; Preoperative Care/methods ; SARS-CoV-2 ; Surveys and Questionnaires
    Keywords covid19
    Language English
    Publishing date 2020-09-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 1328418-6
    ISSN 1469-0691 ; 1470-9465 ; 1198-743X
    ISSN (online) 1469-0691
    ISSN 1470-9465 ; 1198-743X
    DOI 10.1016/j.cmi.2020.09.038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4541: Show issues Location:
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    Zs.MO 284: Show issues

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  8. Article ; Online: Predicting tuberculosis without knowing test specificity.

    Koksalan, O Kaya / Keske, Siran / Yasin, Yesim / Kilicaslan, Zeki

    The Lancet. Infectious diseases

    2016  Volume 16, Issue 11, Page(s) 1221–1222

    MeSH term(s) Humans ; Mycobacterium tuberculosis ; Sensitivity and Specificity ; Tuberculin Test ; Tuberculosis
    Language English
    Publishing date 2016
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(16)30396-6
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    Zs.A 5743: Show issues Location:
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  9. Article ; Online: COVID-19 associated bacterial infections in intensive care unit: a case control study.

    Kaçmaz, Bahar / Keske, Şiran / Sişman, Uluman / Ateş, Sena Tuğana / Güldan, Mustafa / Beşli, Yeşim / Palaoğlu, Erhan / Çakar, Nahit / Ergönül, Önder

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 13345

    Abstract: We described the secondary bacterial infections (SBI) among COVID-19 patients in comparison with non-COVID-19 patients. We performed a retrospective case-control study between January 01, 2020 and April 01, 2022. Including the adult patients, who stayed ≥ ...

    Abstract We described the secondary bacterial infections (SBI) among COVID-19 patients in comparison with non-COVID-19 patients. We performed a retrospective case-control study between January 01, 2020 and April 01, 2022. Including the adult patients, who stayed ≥ 72 h in intensive care unit (ICU). In total 405 patients were included, 135 had (33.3%) COVID-19, with similar age and gender. The length of stay in ICU was not different (11.4 vs 8.2, p = 0.109), however mean intubation days were higher among COVID-19 cases (6.5 vs 3.8, p = 0.005), SBI were more common among COVID-19 cases (34% vs 10.7%, p < 0.001). Among the patients with pneumonia, the rate of gram-positive bacteria was higher in COVID-19 group than the control group (39% vs 5%, p = 0.006). The predictors for SBI were having COVID-19 (OR: 2.3, Cl 1.25-4.32, p = 0.008), days of intubation (OR: 1.05, Cl 1.01-1.10, p = 0.004), and being male (OR: 2, Cl 1.12-3.58, p = 0.018). The predictors of mortality were COVID-19 (OR: 2.38, Cl 1.28-4.42, p = 0.006), days of intubation (OR: 1.06, Cl 1.03-1.09, p < 0.001), active hematologic malignancy (OR: 3.1, Cl: 1.33-7.28, p = 0.09), active solid tumors (OR: 2.44, Cl 1.21-4.91, p = 0.012), and coronary artery diseases (OR: 1.8, Cl 1.01-3.52, p = 0.045). The most common SBI in COVID-19 patients were methicillin-sensitive Staphylococcus aureus. No carbapenem-resistant Enterobacterales related infections were detected in COVID-19 patients.
    MeSH term(s) Adult ; Humans ; Male ; Female ; Case-Control Studies ; COVID-19 ; Retrospective Studies ; Carbapenems ; Coinfection ; Intensive Care Units
    Chemical Substances Carbapenems
    Language English
    Publishing date 2023-08-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-39632-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The challenges in the monitoring of infectious diseases after the earthquake in Türkiye in 2023.

    Ergönül, Önder / Keske, Şiran / Ksinzik, Apolina / Güldan, Mustafa / Özbek, Laşin / Azap, Alpay / Şimşek-Yavuz, Serap / Can, Füsun / Sakarya, Sibel

    The Lancet. Infectious diseases

    2023  Volume 23, Issue 11, Page(s) e482–e488

    Abstract: After the devastating earthquake in Türkiye and Syria in February, 2023, the long-term failure to meet the need for shelter, unfavourable living conditions in tent settlements, poor access to clean drinking water, water suitable for personal hygiene, and ...

    Abstract After the devastating earthquake in Türkiye and Syria in February, 2023, the long-term failure to meet the need for shelter, unfavourable living conditions in tent settlements, poor access to clean drinking water, water suitable for personal hygiene, and sanitary facilities, as well as interruptions in provision of primary health-care services, have emerged as the most important risk factors contributing to the spread of infectious diseases. 3 months after the earthquake, most of these problems persist in Türkiye. Data on the control of infectious diseases are scarce according to the reports prepared by medical specialist associations based on observations of health-care providers working in the region and statements made by the local health authorities. According to these unsystematised data, and considering the conditions in the region, faecal-oral transmissible gastrointestinal infections, as well as respiratory and vector-borne infections, are the main challenges. Vaccine-preventable diseases, such as measles, varicella, meningitis, and polio can be spread in temporary shelters due to interrupted vaccine services and crowded living conditions. In addition to controlling risk factors for infectious diseases, sharing data on the status and control of infectious diseases in the region with the community, health-care providers, and relevant expert groups should be a priority to improve the understanding of the effects of interventions and prepare for possible infectious disease outbreaks.
    MeSH term(s) Humans ; Earthquakes ; Communicable Diseases/epidemiology ; Disease Outbreaks ; Health Services ; Syria
    Language English
    Publishing date 2023-07-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(23)00362-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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