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  1. Article ; Online: Are we responsible for the racial inequalities of covid-19?

    Balakumar, Varathagini / Kirubakaran, Arangan / Tariq, Shabnam

    BMJ (Clinical research ed.)

    2020  Volume 370, Page(s) m2873

    MeSH term(s) COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/ethnology ; Coronavirus Infections/mortality ; Health Status Disparities ; Healthcare Disparities ; Humans ; Pandemics/statistics & numerical data ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/ethnology ; Pneumonia, Viral/mortality ; Racism/statistics & numerical data ; State Medicine ; United Kingdom
    Keywords covid19
    Language English
    Publishing date 2020-07-22
    Publishing country England
    Document type Letter
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.m2873
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Celiac Disease Management in the United Kingdom Specialist Pediatric Gastroenterology Centers-A Service Survey.

    Paul, Siba Prosad / Balakumar, Varathagini / Gillett, Peter Michael

    Journal of pediatric gastroenterology and nutrition

    2021  Volume 72, Issue 6, Page(s) e149–e153

    Abstract: Objectives: The 2012 European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) guidelines on celiac disease (CD) recommended a no-biopsy pathway (NBP) for symptomatic children with high immunoglobin A (IgA)-based anti-tissue ... ...

    Abstract Objectives: The 2012 European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) guidelines on celiac disease (CD) recommended a no-biopsy pathway (NBP) for symptomatic children with high immunoglobin A (IgA)-based anti-tissue transglutaminase (TGA-IgA) titers, positive anti-endomysial antibody and human leukocyte antigen (HLA)-DQ2/DQ8 status. We aimed to understand variations in practice amongst specialist pediatric gastroenterology centers (SPGIC) in the United Kingdom (UK).
    Methods: A survey questionnaire was sent to all UK SPGIC (n = 29) providing endoscopy services for CD diagnosis. It was divided into four main subgroups: analyzing diagnosis of CD through adherence to the ESPGHAN (2012) guidelines, post-diagnosis care and long-term follow-up and discharge from pediatric services.
    Results: All 29 responded. NBP was implemented in 28 of 29 centers. Five of 29 centers had already stopped HLA-DQ2/DQ8 testing for NBP diagnosis. Twenty six of 29 centers were performing endoscopy on screening-identified children (mostly asymptomatic, "at-risk" patients). Diagnosis was communicated by a doctor in 65% SPGIC (n = 19). Most centers (n = 23) waited 6-12 months post-diagnosis to start gluten-free oats. Routine vitamin D supplementation was commenced by 4 of 29 centers. All centers repeated TGA-IgA to assess normalization but at varying times post-GFD. Follow-up was with a combination of doctors/dieticians (n = 26). Eleven of 29 centers discharged their patient to primary care.
    Conclusions: There was excellent uptake of ESPGHAN guidelines (2012) in the UK and adherence to guidelines is generally good. Despite published evidence and pragmatic advice from the British Society of Paediatric Gastroenterology Hepatology and Nutrition and National Institute for Health and Care Excellence, significant differences remain in diagnostic and ongoing management practice and are opportunities for research and directive evidence-based follow-up guidance.
    MeSH term(s) Celiac Disease/diagnosis ; Celiac Disease/therapy ; Child ; Disease Management ; Gastroenterology ; Humans ; Surveys and Questionnaires ; Transglutaminases ; United Kingdom
    Chemical Substances Transglutaminases (EC 2.3.2.13)
    Language English
    Publishing date 2021-04-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603201-1
    ISSN 1536-4801 ; 0277-2116
    ISSN (online) 1536-4801
    ISSN 0277-2116
    DOI 10.1097/MPG.0000000000003126
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online: Are we responsible for the racial inequalities of covid-19?

    Balakumar, Varathagini / Kirubakaran, Arangan / Tariq, Shabnam

    2020  

    Keywords LETTERS ; covid19
    Language English
    Publishing date 2020-07-22 02:26:22.0
    Publisher BMJ Publishing Group Ltd
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Are we responsible for the racial inequalities of covid-19?

    Balakumar, Varathagini / Kirubakaran, Arangan / Tariq, Shabnam

    BMJ

    2020  , Page(s) m2873

    Keywords covid19
    Language English
    Publisher BMJ
    Publishing country uk
    Document type Article ; Online
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.m2873
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Turnaround times for molecular testing of pediatric viral cerebrospinal fluid samples in United Kingdom laboratories.

    Paul, Siba Prosad / Balakumar, Varathagini / Kirubakaran, Arangan / Niharika, Jothilingam / Heaton, Paul Anthony / Turner, Paul Christopher

    World journal of clinical pediatrics

    2022  Volume 11, Issue 3, Page(s) 289–294

    Abstract: Background: Rapid molecular testing has revolutionized the management of suspected viral meningitis and encephalitis by providing an etiological diagnosis in < 90 min with potential to improve outcomes and shorten inpatient stays. However, use of ... ...

    Abstract Background: Rapid molecular testing has revolutionized the management of suspected viral meningitis and encephalitis by providing an etiological diagnosis in < 90 min with potential to improve outcomes and shorten inpatient stays. However, use of molecular assays can vary widely.
    Aim: To evaluate current practice for molecular testing of pediatric cerebrospinal fluid (CSF) samples across the United Kingdom using a structured questionnaire.
    Methods: A structured telephone questionnaire survey was conducted between July and August 2020. Data was collected on the availability of viral CSF nucleic acid amplification testing (NAAT), criteria used for testing and turnaround times including the impact of the coronavirus disease 2019 pandemic.
    Results: Of 196/212 (92%) microbiology laboratories responded; 63/196 (32%) were excluded from final analysis as they had no on-site microbiology laboratory and outsourced their samples. Of 133 Laboratories included in the study, 47/133 (35%) had onsite facilities for viral CSF NAAT. Hospitals currently undertaking onsite NAAT (
    Conclusion: Onsite/near-patient rapid NAAT (including polymerase chain reaction) is recommended wherever possible to optimize patient management in the acute setting.
    Language English
    Publishing date 2022-03-18
    Publishing country United States
    Document type Journal Article
    ISSN 2219-2808
    ISSN 2219-2808
    DOI 10.5409/wjcp.v11.i3.289
    Database MEDical Literature Analysis and Retrieval System OnLINE

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