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  1. Article ; Online: Intervention du Pr G. Friedmann (Paris)

    Georges Friedmann

    Perspectives Interdisciplinaires sur le Travail et la Santé, Vol 19, Iss

    2017  Volume 3

    Keywords Medicine ; R ; Social history and conditions. Social problems. Social reform ; HN1-995
    Language English
    Publishing date 2017-11-01T00:00:00Z
    Publisher Institut de Recherche Robert-Sauvé en Santé et en Sécurité du Travail (IRSST)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Impact of Resistance Exercise and Nutritional Endorsement on physical performance in patients with GvHD (IRENE-G study) - design and rational of a randomized controlled trial.

    Bujan Rivera, Janina / Kühl, Rea / Zech, Ulrike / Hendricks, Anne / Luft, Thomas / Dreger, Peter / Friedmann-Bette, Birgit / Betz, Theresa-Maria / Wiskemann, Joachim

    BMC cancer

    2022  Volume 22, Issue 1, Page(s) 440

    Abstract: ... Study (IRENE-G) is to evaluate the effects of resistance exercise in combination with nutritional ... endorsement on physical, nutritional and patient-reported outcomes in GvHD patients.: Methods: IRENE-G is ...

    Abstract Background: Graft-versus-host disease (GvHD) remains a major complication and limitation to successful allogeneic hematopoietic stem cell transplantation. Treatment of GvHD is challenging due to its heterogeneous nature of presentation, with steroids remaining the established first-line treatment. Long-term doses of systemic corticosteroids have many well-known side-effects including muscle atrophy. Despite the fact that reports in non-cancer clinical populations treated with glucocorticoids demonstrated that resistance training can reverse atrophy and weakness, no RCT has evaluated the potential of resistance training on preventing the disease- and treatment-induced loss of skeletal muscle mass and function in GvHD patients yet. In this context, ensuring adequate nutrition is important as protein deprivation may accelerate the wasting process. As GvHD patients are commonly found to be malnourished, nutritional medical care should be considered when investigating the effect of exercise in GvHD patients. Therefore, the aim of the present "Impact of Resistance Exercise and Nutritional Endorsement on physical performance in patients with GvHD" - Study (IRENE-G) is to evaluate the effects of resistance exercise in combination with nutritional endorsement on physical, nutritional and patient-reported outcomes in GvHD patients.
    Methods: IRENE-G is a 24-week prospective interventional RCT. One hundred twelve participants will be randomly allocated (1:1) to one of two arms: resistance exercise and nutritional optimization (experimental) vs. nutritional optimization only (control). Participants in the experimental group will engage in a supervised, progressive moderate-to-high intensity resistance training that is consistent with exercise guidelines for cancer patients, while additionally receiving nutritional support/therapy. Subjects of the control group solely receive nutritional support/therapy based on individual needs. Participants will be assessed at baseline, at 8, 16, 24 weeks for physical performance and various physiological, nutritional and patient-reported outcomes. Follow-up will be 6 months after intervention completion.
    Discussion: To our knowledge, this will be the first RCT to assess and compare the effects of a resistance intervention supplemented by nutritional support/therapy against nutritional support only on various health-related outcomes in GvHD patients. The study will contribute to our understanding of the value of exercise and nutritional endorsement in counteracting the negative consequences of GvHD and its treatment.
    Trial registration: ClinicalTrials.gov : NCT05111834 . Registered 8 November 2021 - Retrospectively registered.
    MeSH term(s) Exercise ; Graft vs Host Disease/etiology ; Graft vs Host Disease/therapy ; Humans ; Physical Functional Performance ; Prospective Studies ; Resistance Training
    Language English
    Publishing date 2022-04-22
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2041352-X
    ISSN 1471-2407 ; 1471-2407
    ISSN (online) 1471-2407
    ISSN 1471-2407
    DOI 10.1186/s12885-022-09497-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Comparison Of Iqwig and G-BA Benefit Ratings in Oncology.

    Schuchardt, M / Khoury, C / Friedmann, B / Haigh, J

    Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

    2014  Volume 17, Issue 7, Page(s) A544

    Language English
    Publishing date 2014-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1471745-1
    ISSN 1524-4733 ; 1098-3015
    ISSN (online) 1524-4733
    ISSN 1098-3015
    DOI 10.1016/j.jval.2014.08.1758
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Online: Root, Tuber and Banana Food System Innovations

    Thiele, Graham / Friedmann, Michael / Campos, Hugo / Polar, Vivian / Bentley, Jeffery W.

    Value Creation for Inclusive Outcomes

    2022  

    Keywords Agricultural science ; Genetics (non-medical) ; Business & management ; Scalling innovation ; tropical crops ; banana ; cassava ; sweet potato ; yams ; agriculture value creation ; crop waste management ; digital pest control ; citizen science
    Language 0|e
    Size 1 electronic resource (561 pages)
    Publisher Springer Nature
    Publishing place Cham
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021609739
    ISBN 9783030920227 ; 3030920224
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Book ; Conference proceedings: Leben und Werk von Friedrich G. Friedmann

    Ammon, Herbert / Friedmann, Friedrich G / Hinz, Manfred / Zak, Adam

    drei Vorträge im Rahmen eines Symposiums der Jüdischen Kulturwochen 1995 am 16. November 1995 an der Universität Augsburg

    (Augsburger Universitätsreden ; 30)

    1997  

    Institution Jüdische Kulturwochen
    Universität Augsburg
    Event/congress Symposium der Jüdischen Kulturwochen (1995.11.16, Augsburg)
    Author's details von Manfred Hinz; Herbert Ammon; Adam Zak
    Series title Augsburger Universitätsreden ; 30
    Language German
    Size 79 S, 1 Portr, 21 cm
    Publisher Rektor der Universität Augsburg
    Publishing place Augsburg
    Document type Book ; Conference proceedings
    Database Former special subject collection: coastal and deep sea fishing

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  6. Book: PFLEGENOTSTAND UND MODERNE MEDIZIN

    Hohlbrugger, Gero / Stronegger, Willibald / Rudolph, Enno / Friedmann, Felix / Pichler, Klaus

    Eine Herausforderung für uns alle

    (plattform SCIENTIA)

    2022  

    Abstract: Auf Neugier und Ehrgeiz der Naturwissenschaftler beruhen die unbestreitbaren Erfolge der modernen, westlichen Medizin. Insbesondere -- die durchschnittliche Lebenserwartung wurde mehr als verdoppelt. Aber auch die Jahre der Pflegebedürftigkeit haben sich ...

    Author's details 1948 21.April, Geburt, Innsbruck, Österreich§1974 Promotion zum Doktor der gesamten Heilkunde, Universität Innsbruck§1982 Preis der Stiftung "Höchst", Medizinische Fakultät, Universität Innsbruck§ Facharzt f. Urologie§1984 Förderungspreis der österr. Ges. f. Nephrologie§ Praxisgründung, Dornbirn§1988 Habilitationim Fach Urologie, Universität Innsbruck§1992 Fellow of the European Board of Urology§1997 „Invited speaker“ NIH (National Institue of Health/USA)§1998 Honorary mention bei „Int. Jaques Lapides essay contest“,§ Ausserordentlicher Universitätsprofessor §2003 Gründungsmitglied von ESSIC (Europ. Study Group for the Study of IC)
    Series title plattform SCIENTIA
    Abstract Auf Neugier und Ehrgeiz der Naturwissenschaftler beruhen die unbestreitbaren Erfolge der modernen, westlichen Medizin. Insbesondere -- die durchschnittliche Lebenserwartung wurde mehr als verdoppelt. Aber auch die Jahre der Pflegebedürftigkeit haben sich pro PatientIn nahezu verzehnfacht. Das bedeutet Überalterung. Seit ca. 2 Jahren kann der Pflegebedarf kaum noch bewältigt werden. Wegen des „Pflegenotstands“ müssen nicht nur in Altenheimen, sondern auch in Kliniken Stationen aufgegeben werd...
    Keywords Sterbebegleitung ; Angst vor dem Lebensende ; Linderung der Todesangst ; Spiritualität ; Ethik ; „Sterben-lernen“ ; palliative Sedierung ; Pflege ; Moderne Medizin ; Pflegenotstand ; Sterben ; Religion ; Medizin
    Language German
    Size 120 p.
    Edition 1
    Publisher plattform Verlag
    Document type Book
    Note PDA Manuell_16
    ISBN 9783950495478 ; 3950495479
    Database PDA

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  7. Book: Borderline-Persönlichkeitsstörung

    Dulz, Birger / Lohmer, Mathias / Kernberg, Otto F. / Wlodarczyk, Olga / Dammann, Gerhard / Holler, Petra

    stationäre übertragungsfokussierte Psychotherapie

    (Praxis der psychodynamischen Psychotherapie - analytische und tiefenpsychologisch fundierte Psychotherapie ; Band 13)

    2022  

    Author's details Birger Dulz, Mathias Lohmer, Otto F. Kernberg, Olga Wlodarczyk, Gerhard Dammann ; Prolog aus dem amerikanischen Englisch übersetzt von Petra Holler
    Series title Praxis der psychodynamischen Psychotherapie - analytische und tiefenpsychologisch fundierte Psychotherapie ; Band 13
    Collection
    Keywords Borderline-Persönlichkeitsstörung ; Klinische Psychotherapie ; Übertragungsfokussierte Psychotherapie
    Subject Transference-focused Psychotherapy ; Transference focused Psychotherapy ; TFP ; Stationäre Behandlung ; Stationäre Psychotherapie ; Borderline-Syndrom ; Borderlinesyndrom
    Language German
    Size VII, 136 Seiten, Illustrationen, 24 cm x 16.5 cm
    Edition 1. Auflage
    Publisher Hogrefe
    Publishing place Göttingen
    Publishing country Germany
    Document type Book
    HBZ-ID HT021261557
    ISBN 978-3-8017-2588-4 ; 3-8017-2588-X ; 9783840925887 ; 9783844425888 ; 3840925886 ; 3844425888
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  8. Book: Schizoidie und schizoide Persönlichkeitsstörung

    Dammann, Gerhard / Kernberg, Otto F.

    Psychodynamik - Diagnostik - Psychotherapie

    (Psychotherapie in Psychiatrie und Psychosomatik)

    2019  

    Author's details Gerhard Dammann, Otto F. Kernberg (Hrsg.)
    Series title Psychotherapie in Psychiatrie und Psychosomatik
    Keywords Autismus-Spektrum-Störung ; Persönlichkeitsstörung ; Psychiatrische Syndrome ; Schizophrenie ; Schizoidie ; Schizoide Persönlichkeitsstörung
    Subject code 610
    Language German
    Size 252 Seiten, Illustrationen, Diagramme
    Edition 1. Auflage
    Publisher Verlag W. Kohlhammer
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    HBZ-ID HT019887741
    ISBN 978-3-17-033467-0 ; 3-17-033467-0 ; 9783170334687 ; 9783170334694 ; 9783170334700 ; 3170334689 ; 3170334697 ; 3170334700
    Database Catalogue ZB MED Medicine, Health

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  9. Article: Letter Migrations between Words in Reading Aloud Can Result either from an Impairment in Orthographic Input or in Phonological Output.

    Toledano, Liora / Friedmann, Naama

    Brain sciences

    2023  Volume 13, Issue 4

    Abstract: Letter migrations between words in reading aloud (e.g., reading "cane love" as "lane love" or "lane ...

    Abstract Letter migrations between words in reading aloud (e.g., reading "cane love" as "lane love" or "lane cove") are known to result from a deficit in the visual-orthographic analysis and characterize attentional dyslexia. In spontaneous speech, individuals with impairment in the phonological output buffer may show migrations of phonemes between words. The purpose of this study was to examine whether migrations between words in reading aloud can also result from a deficit in the phonological output buffer, to explore the characteristics of migrations resulting from orthographic input and from phonological output deficits, and to examine methods to distinguish these two sources. Using tasks of reading aloud of lists of 92-182 word pairs, we identified 18 adults and adolescents with developmental dyslexia who made between-word letter migrations in reading aloud, significantly more than age-matched controls (372 adults, 26 7th-graders and 44 4th-5th-graders). To distinguish between the orthographic input and phonological output sources for these migrations, we administered a test assessing orthographic input without spoken output (written semantic decision on 140 migratable word pairs) and a repetition test of 36 auditorily presented migratable word pairs, assessing spoken output without orthographic input (as well as nonword repetition and 3 span tests). These tests indicated that the migrations in reading aloud of 10 of the participants with dyslexia resulted from an orthographic input deficit-they made migrations not only in reading aloud but also in written word pair comprehension, but not in word pair repetition. For the other 8 participants, the migrations resulted from a phonological output deficit: they made migrations in reading aloud and in word pair repetition, but not in comprehension, and had limited spans and made errors in nonword repetition. We identified several differences between the two types of between-word errors: first, the individuals with attentional dyslexia made omissions of a letter that appeared in the same position in the two words, but the phonological output buffer group did not make such omissions. Second, the groups differed in the origin of migration: orthographic input migrations involve letters that are orthographically adjacent, whereas phonological output migrations involve phonologically adjacent phonemes: phonemes that have just been spoken or that are prepared together in the phonological buffer for production. Migrations from the line below and from 2 lines above the target occurred only in the orthographic input group. This study thus indicates that between-word migrations in reading aloud can result not only from attentional dyslexia, but also from a phonological output buffer deficit, and offers ways to distinguish between the two.
    Language English
    Publishing date 2023-03-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci13040588
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Demonstration of the presence of G-proteins in hepatic microsomal fraction.

    Codina, J / Kimura, S / Kraus-Friedmann, N

    Biochemical and biophysical research communications

    1988  Volume 150, Issue 2, Page(s) 848–852

    Abstract: The presence of G-proteins in isolated hepatic microsomal vesicles is demonstrated. The G-proteins ... identified a 40 kDa protein corresponding to alpha i. The microsomal G-proteins are identical ... to the corresponding G proteins of the plasma membrane, but are present in different proportions; the microsomes have ...

    Abstract The presence of G-proteins in isolated hepatic microsomal vesicles is demonstrated. The G-proteins were identified by their capacity to be ADP-ribosylated by cholera and pertussis toxins. Cholera toxin identified 42 and 45 kDa proteins, corresponding to alpha s-1 and alpha s-2, respectively. Pertussis toxin identified a 40 kDa protein corresponding to alpha i. The microsomal G-proteins are identical to the corresponding G proteins of the plasma membrane, but are present in different proportions; the microsomes have considerably less alpha s proteins than the plasma membrane.
    MeSH term(s) Adenosine Diphosphate Ribose/metabolism ; Animals ; Cell Membrane/metabolism ; Cholera Toxin/metabolism ; GTP-Binding Proteins/metabolism ; Glucose-6-Phosphatase/metabolism ; Liver/metabolism ; Male ; Microsomes, Liver/metabolism ; Molecular Weight ; Pertussis Toxin ; Rats ; Rats, Inbred Strains ; Sodium-Potassium-Exchanging ATPase/metabolism ; Virulence Factors, Bordetella/metabolism
    Chemical Substances Virulence Factors, Bordetella ; Adenosine Diphosphate Ribose (20762-30-5) ; Cholera Toxin (9012-63-9) ; Pertussis Toxin (EC 2.4.2.31) ; Glucose-6-Phosphatase (EC 3.1.3.9) ; GTP-Binding Proteins (EC 3.6.1.-) ; Sodium-Potassium-Exchanging ATPase (EC 3.6.3.9)
    Language English
    Publishing date 1988-01-29
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 205723-2
    ISSN 0006-291X ; 0006-291X
    ISSN (online) 0006-291X
    ISSN 0006-291X
    DOI 10.1016/0006-291x(88)90469-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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