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  1. Book: Ling lei yue ting

    Cai, Zhenjia

    biao yan yi shu zhong de da nao ji bing yu yin sheng yi chang

    2011  

    Title variant Alternative watching/listening : brain diseases and voice disorders in performing arts
    Author's details Cai Zhenjia zhu
    MeSH term(s) Brain Diseases ; Voice Disorders
    Language Chinese
    Size 367 p. :, ill.
    Edition Chu ban.
    Publisher Guo li Taiwan da xue chu ban zhong xin
    Publishing place Taibei Shi
    Document type Book
    ISBN 9789860271560 ; 9860271569
    Database Catalogue of the US National Library of Medicine (NLM)

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  2. Article: Equivalence of Lei and Ting balance equations for nonlinear electronic transport and a Boltzmann approach.

    Marchetti / Cai

    Physical review. B, Condensed matter

    1987  Volume 36, Issue 15, Page(s) 8159–8161

    Language English
    Publishing date 1987-11-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209770-9
    ISSN 1095-3795 ; 1550-235X ; 0163-1829 ; 2469-9950 ; 1098-0121 ; 0556-2805
    ISSN (online) 1095-3795 ; 1550-235X
    ISSN 0163-1829 ; 2469-9950 ; 1098-0121 ; 0556-2805
    DOI 10.1103/physrevb.36.8159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Application of machine learning in the prediction of recurrent ischemic stroke.

    Tian, Ting / Cai, Hongbin

    Minerva medica

    2024  

    Language English
    Publishing date 2024-01-15
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 123586-2
    ISSN 1827-1669 ; 0026-4806
    ISSN (online) 1827-1669
    ISSN 0026-4806
    DOI 10.23736/S0026-4806.23.08991-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Gastrointestinal bleeding by gastroduodenal artery pseudoaneurysm.

    Zhou, Ting-Ting / Cai, Fei / Liu, Wei

    The American journal of the medical sciences

    2023  Volume 366, Issue 2, Page(s) e29–e30

    MeSH term(s) Humans ; Aneurysm, False/complications ; Aneurysm, False/diagnostic imaging ; Aneurysm, False/therapy ; Duodenum/diagnostic imaging ; Pancreatitis ; Arteries ; Gastrointestinal Hemorrhage/etiology
    Language English
    Publishing date 2023-04-19
    Publishing country United States
    Document type Letter
    ZDB-ID 82078-7
    ISSN 1538-2990 ; 0002-9629
    ISSN (online) 1538-2990
    ISSN 0002-9629
    DOI 10.1016/j.amjms.2023.03.027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Pharmacological activities of esculin and esculetin: A review.

    Cai, Ting / Cai, Bin

    Medicine

    2023  Volume 102, Issue 40, Page(s) e35306

    Abstract: Esculin and esculetin are 2 widely studied coumarin components of Cortex Fraxini, which is a well-known herbal medicine with a 2000-year history. In vivo and in vitro studies have demonstrated that both have a variety of pharmacological activities, ... ...

    Abstract Esculin and esculetin are 2 widely studied coumarin components of Cortex Fraxini, which is a well-known herbal medicine with a 2000-year history. In vivo and in vitro studies have demonstrated that both have a variety of pharmacological activities, including antioxidant, anti-tumor, anti-inflammatory, antibacterial, antidiabetic, immunomodulatory, anti-atherosclerotic, and so on. Their underlying mechanisms of action and biological activities include scavenging free radicals, modulating the nuclear factor erythroid 2-related factor 2 pathway, regulating the cell cycle, inhibiting tumor cell proliferation and migration, promoting mitochondrial pathway apoptosis, inhibiting the NF-κB and MAPK signaling pathways, regulating CD4+ T cells differentiation and associated cytokine release, inhibiting vascular smooth muscle cells, etc. This review aims to provide comprehensive information on pharmacological studies of esculin and esculetin, which is of noteworthy importance in exploring the therapeutic potential of both coumarin compounds.
    MeSH term(s) Humans ; Esculin/pharmacology ; Esculin/therapeutic use ; Umbelliferones/pharmacology ; Umbelliferones/therapeutic use ; Coumarins/pharmacology ; Coumarins/therapeutic use ; Apoptosis
    Chemical Substances esculetin (SM2XD6V944) ; Esculin (1Y1L18LQAF) ; Umbelliferones ; Coumarins
    Language English
    Publishing date 2023-10-06
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000035306
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Network pharmacology and molecular docking reveal potential mechanism of esculetin in the treatment of ulcerative colitis.

    Cai, Ting / Cai, Bin

    Medicine

    2023  Volume 102, Issue 45, Page(s) e35852

    Abstract: Ulcerative colitis (UC) is a chronic inflammatory bowel disease of the colonic mucosa. Esculetin is a type of natural coumarin that has many pharmacological activities such as antioxidant, anticancer, anti-inflammatory, etc. A previous study showed that ... ...

    Abstract Ulcerative colitis (UC) is a chronic inflammatory bowel disease of the colonic mucosa. Esculetin is a type of natural coumarin that has many pharmacological activities such as antioxidant, anticancer, anti-inflammatory, etc. A previous study showed that esculetin improved intestinal inflammation and reduced serum proinflammatory cytokines in UC. The present study aimed to utilize network pharmacology and molecular docking to explore the potential mechanism of esculetin against UC. The potential gene targets of esculetin were predicted through SwissTargetPrediction and Super-PRED web servers. UC-related genes were obtained from DisGeNet, OMIM, and GeneCards databases. The overlap between gene targets of esculetin and UC-related genes were identified as the potential targets of esculetin against UC. The interaction between these overlapping genes was analyzed by the STRING database and the core genes were identified by Cytoscape platform. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis of the core genes were then performed. And the results of these analyses were further confirmed through molecular docking. A total of 50 overlapping genes were identified as the potential action targets of esculetin against UC. Among them, 10 genes (AKT1, STAT1, CCND1, SRC, PTGS2, EGFR, NFKB1, ESR1, MMP9, SERPINE1) were finally identified as the core genes. The Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis results showed that the top signaling pathway associated with the core genes of esculetin against UC was the prolactin (PRL) signaling pathway. Molecular docking results showed that esculetin has a strong binding affinity to the core genes, as well as PRL and prolactin receptor. This study suggests that esculetin may have a crucial impact on UC through the PRL signaling pathway and provides insights into the potential mechanism of esculetin in the treatment of UC, which may shed light on the mechanism and treatment of UC.
    MeSH term(s) Humans ; Colitis, Ulcerative/drug therapy ; Colitis, Ulcerative/genetics ; Molecular Docking Simulation ; Network Pharmacology ; Umbelliferones/pharmacology ; Umbelliferones/therapeutic use
    Chemical Substances esculetin (SM2XD6V944) ; Umbelliferones
    Language English
    Publishing date 2023-11-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000035852
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Covalent Organic Framework-Semiconductor-Based Heterostructures for Photocatalytic Applications.

    Chen, Kai / Cai, Anqi / Li, Ting-Ting

    ChemSusChem

    2023  Volume 16, Issue 10, Page(s) e202300021

    Abstract: Photocatalysis is a promising and sustainable technology in the fields of energy conversion/storage and environment purification; however, the utilization of individual component as photocatalyst is generally restricted due to the low catalytic activity ... ...

    Abstract Photocatalysis is a promising and sustainable technology in the fields of energy conversion/storage and environment purification; however, the utilization of individual component as photocatalyst is generally restricted due to the low catalytic activity deriving from the rapid recombination of photogenerated electrons/holes. Covalent organic framework (COF)-semiconductor-based composite photocatalysts with synergistic effects provide a feasible route to achieve high-performance photocatalytic reactions with more active sites, strong light utilization ability, and high stability. In recent years, significant progress has been made in the rational design and preparation of the COF-semiconductors-based heterostructures for photocatalytic water splitting, carbon dioxide (CO
    Language English
    Publishing date 2023-03-24
    Publishing country Germany
    Document type Journal Article ; Review
    ISSN 1864-564X
    ISSN (online) 1864-564X
    DOI 10.1002/cssc.202300021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Shape memory and self-healing in a molecular crystal with inverse temperature symmetry breaking.

    Meng, Jiantao / Su, Yuan / Zhu, Hang / Cai, Ting

    Chemical science

    2024  Volume 15, Issue 15, Page(s) 5738–5745

    Abstract: Mechanically responsive molecular crystals have attracted increasing attention for their potential as actuators, sensors, and switches. However, their inherent structural rigidity usually makes them vulnerable to external stimuli, limiting their usage in ...

    Abstract Mechanically responsive molecular crystals have attracted increasing attention for their potential as actuators, sensors, and switches. However, their inherent structural rigidity usually makes them vulnerable to external stimuli, limiting their usage in many applications. Here, we present the mechanically compliant single crystals of penciclovir, a first-line antiviral drug, achieved through an unconventional ferroelastic transformation with inverse temperature symmetry breaking. These crystals display a diverse set of self-restorative behaviors well above room temperature (385 K), including ferroelasticity, superelasticity, and shape memory effects, suggesting their promising applications in high-temperature settings. Crystallographic analysis reveals that cooperative molecular displacement within the layered crystal structure is responsible for these unique properties. Most importantly, these ferroelastic crystals manifest a polymer-like self-healing behavior even after severe cracking induced by thermal or mechanical stresses. These findings suggest the potential for similar memory and restorative effects in other molecular crystals featuring layered structures and provide valuable insights for leveraging organic molecules in the development of high-performance, ultra-flexible molecular crystalline materials with promising applications.
    Language English
    Publishing date 2024-03-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2559110-1
    ISSN 2041-6539 ; 2041-6520
    ISSN (online) 2041-6539
    ISSN 2041-6520
    DOI 10.1039/d3sc06800e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Changes in the intestinal microbiota of individuals with non-alcoholic fatty liver disease based on sequencing: An updated systematic review and meta-analysis.

    Cai, Wenpin / Qiu, Ting / Hu, Weitao / Fang, Taiyong

    PloS one

    2024  Volume 19, Issue 3, Page(s) e0299946

    Abstract: Background: Alterations in the composition and abundance of the intestinal microbiota occur in non-alcoholic fatty liver disease (NAFLD). However, the results are inconsistent because of differences in the study design, subject area, and sequencing ... ...

    Abstract Background: Alterations in the composition and abundance of the intestinal microbiota occur in non-alcoholic fatty liver disease (NAFLD). However, the results are inconsistent because of differences in the study design, subject area, and sequencing methodology. In this study, we compared the diversity and abundance of the intestinal microbiota of patients with NAFLD and healthy individuals through a systematic review and meta-analysis.
    Methods: Three databases (PubMed, EMBASE, and Cochrane Library) were searched from their inception to March 20, 2023. A meta-analysis was performed using Stata software to analyze variations in the richness and abundance of the intestinal microbiota in patients with NAFLD. The Newcastle-Ottawa Quality Assessment Scale (NOS) was used for quality assessment.
    Results: A total of 28 articles were included. Shannon diversity was reduced in patients with NAFLD (SMD = -0.24 (95% CI -0.43-0.05, I2 = 71.7%). The relative abundance of Ruminococcus, Faecalibacterium, and Coprococcus all decreased, with total SMDs of -0.96 (95% CI -1.29 to -0.63, I2 = 4.8%), -1.13 (95% CI -2.07 to -0.19, I2 = 80.5%), and -1.66 (95% CI -3.04 to -0.28, I2 = 91.5%). Escherichia was increased in individuals with NAFLD (SMD = 1.78, 95% CI 0.12 to 3.45, I2 = 94.4%).
    Conclusion: Increasing the species diversity and altering the abundance of specific gut microbiota, including Coprococcus, Faecalibacterium, Ruminococcus, and Escherichia, may be beneficial for improving NAFLD.
    MeSH term(s) Humans ; Non-alcoholic Fatty Liver Disease/microbiology ; Gastrointestinal Microbiome/genetics ; Gram-Positive Cocci ; Faecalibacterium ; Research Design ; Clostridiales
    Language English
    Publishing date 2024-03-28
    Publishing country United States
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0299946
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Care Models and Barriers to Long-Term Follow-Up Care Among Childhood Cancer Survivors and Health Care Providers in Asia: A Literature Review.

    Cai, Jiaoyang / Cheung, Yin Ting / Hudson, Melissa M

    JCO global oncology

    2024  Volume 10, Page(s) e2300331

    Abstract: Most available data evaluating childhood cancer survivorship care focus on the experiences of high-income Western countries, whereas data from Asian countries are limited. To address this knowledge deficit, we aimed to characterize survivorship care ... ...

    Abstract Most available data evaluating childhood cancer survivorship care focus on the experiences of high-income Western countries, whereas data from Asian countries are limited. To address this knowledge deficit, we aimed to characterize survivorship care models and barriers to participation in long-term follow-up (LTFU) care among childhood cancer survivors (CCSs) and health care providers in Asian countries. Twenty-four studies were identified. Most institutions in China and Turkey adopt the oncology specialist care model, whereas in Japan, India, Singapore, and South Korea, after completion of therapy LTFU programs are available in some institutions. In terms of survivor barriers, findings highlight the need for comprehensive age-appropriate education and support and personalized approaches in addressing individual preferences and challenges during survivorship. Health care professionals need education about potential late effects of cancer treatment, recommended guidance for health surveillance and follow-up care, and their role in facilitating the transition from pediatric to adult-focused care. To optimize the delivery of cancer survivorship care, efforts are needed to increase patient and family awareness about the purpose and potential benefits of LTFU care, improve provider education and training, and promote policy change to ensure that CCSs have access to essential services and resources to optimize quality of survival.
    MeSH term(s) Adult ; Humans ; Child ; Cancer Survivors ; Neoplasms/therapy ; Neoplasms/epidemiology ; Follow-Up Studies ; Asia ; Health Personnel
    Language English
    Publishing date 2024-03-06
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2687-8941
    ISSN (online) 2687-8941
    DOI 10.1200/GO.23.00331
    Database MEDical Literature Analysis and Retrieval System OnLINE

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