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Article: Evaluating Protein Fouling on Membranes Patterned by Woven Mesh Fabrics.

Malakian, Anna / Husson, Scott M

2021 Volume 11, Issue 10

Abstract: Membrane surface patterning is one approach used to mitigate fouling. This study used a combination of flux decline measurements and visualization experiments to evaluate the effectiveness of a microscale herringbone pattern for reducing protein fouling ... ...

Abstract	Membrane surface patterning is one approach used to mitigate fouling. This study used a combination of flux decline measurements and visualization experiments to evaluate the effectiveness of a microscale herringbone pattern for reducing protein fouling on polyvinylidene fluoride (PVDF) ultrafiltration membranes. Thermal embossing with woven mesh stamps was used for the first time to pattern membranes. Embossing process parameters were studied to identify conditions replicating the mesh patterns with high fidelity and to determine their effect on membrane permeability. Permeability increased or remained constant when patterning at low pressure (≤4.4 MPa) as a result of increased effective surface area; whereas permeability decreased at higher pressures due to surface pore-sealing of the membrane active layer upon compression. Flux decline measurements with dilute protein solutions showed monotonic decreases over time, with lower rates for patterned membranes than as-received membranes. These data were analyzed by the Hermia model to follow the transient nature of fouling. Confocal laser scanning microscopy (CLSM) provided complementary, quantitative, spatiotemporal information about protein deposition on as-received and patterned membrane surfaces. CLSM provided a greater level of detail for the early (pre-monolayer) stage of fouling than could be deduced from flux decline measurements. Images show that the protein immediately started to accumulate rapidly on the membranes, likely due to favorable hydrophobic interactions between the PVDF and protein, followed by decreasing rates of fouling with time as protein accumulated on the membrane surface. The knowledge generated in this study can be used to design membranes that inhibit fouling or otherwise direct foulants to deposit selectively in regions that minimize loss of flux.
Language	English
Publishing date	2021-09-25
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2614641-1
ISSN	2077-0375
ISSN	2077-0375
DOI	10.3390/membranes11100730
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Activité définitoire folk et argumentation en contexte polémique

Anne-Charlotte Husson

Corela, Vol

2020 Volume 31

Abstract: This article analyses folk definitory activities, understood as a set of utterances with a definitory dimension. These utterances manifest a relationship to language, others, and the world which is specific to folk speakers. The article sets itself apart ...

Abstract	This article analyses folk definitory activities, understood as a set of utterances with a definitory dimension. These utterances manifest a relationship to language, others, and the world which is specific to folk speakers. The article sets itself apart from those analyses which, while looking mostly at the forms assumed by such activity, only consider them in terms of deficiency compared to their learned relatives, lexicographic definitions. This work puts forward some formal, textual, discursive, pragmatic, and enunciative features of folk definitions, and considers such definitions as a vantage point for heterogeneity in polemical contexts, more precisely in the context of the controversy about gender which takes place in the French public sphere between 2011 and 2014. By analysing the processes by which meanings become conflictual within this controversy, the author emphasises a key paradox, thus interrogating dialogal conceptions of discourse: although polemical discourse requires to maintain a relationship (albeit a very tenuous one) with the adversary, this fragile tether is also a way to establish the difference, and even incommensurability, between both sides of a controversy.
Keywords	heterogeneity – folk definitory activities – argumentation – meaning and conflict – controversy about gender in France ; Anthropology ; GN1-890 ; Language and Literature ; P ; Philosophy. Psychology. Religion ; B
Subject code	400
Language	English
Publishing date	2020-06-01T00:00:00Z
Publisher	Cercle linguistique du Centre et de l'Ouest - CerLICO
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The importance of a collaborative health-related quality of life measurement strategy for adolescents and young adults with cancer.

Husson, Olga / Sodergren, Samantha C / Darlington, Anne-Sophie

Cancer

2021 Volume 127, Issue 10, Page(s) 1712–1713

MeSH term(s)	Adolescent ; Humans ; Neoplasms/therapy ; Quality of Life ; Surveys and Questionnaires ; Young Adult
Language	English
Publishing date	2021-01-26
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	1429-1
ISSN	1097-0142 ; 0008-543X ; 1934-662X
ISSN (online)	1097-0142
ISSN	0008-543X ; 1934-662X
DOI	10.1002/cncr.33416
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Article: Two decades of Pseudo-nitzschia spp. blooms and king scallop (Pecten maximus) contamination by domoic acid along the French Atlantic and English Channel coasts: Seasonal dynamics, spatial heterogeneity and interannual variability

Husson, Bérengère / Annie Chapelle / Mathilde Schapira / Romain Le Gendre / Tania Hernández-Fariñas

Harmful algae. 2016 Jan., v. 51

2016

Abstract: King scallop contamination (Pecten maximus) by domoic acid, a neurotoxin produced by some species of the diatom Pseudo-nitzschia, is highly problematic because of its lengthy retention in the bivalve tissue, leading to prolonged fishery closures. Data ... ...

Abstract	King scallop contamination (Pecten maximus) by domoic acid, a neurotoxin produced by some species of the diatom Pseudo-nitzschia, is highly problematic because of its lengthy retention in the bivalve tissue, leading to prolonged fishery closures. Data collected within the French Phytoplankton and Phycotoxin monitoring network (REPHY) over the 1995–2012 period were used to characterize the seasonal dynamics and the interannual variability of P.-nitzschia spp. blooms as well as the contamination of king scallop fishing grounds, in six contrasted bays distributed along the French Atlantic coast and English Channel. Monitoring revealed that these toxic events have become more frequent since the year 2000, but with varying magnitudes, frequencies and timing depending on the bay. Two bays, located in southern Brittany, exhibited both recurrent contaminations and high P.-nitzschia abundances. The Brest bay and the Seine bay were intermittently affected. The Pertuis Breton exhibited only one major toxic event related to an exceptionally intense bloom of P.-nitzschia in 2010, and the Saint Brieuc bay neither showed significant contamination nor high P.-nitzschia abundance. While high P.-nitzschia abundance appeared to be correlated to scallop toxicity, this study highlights the difficulty in linking P.-nitzschia spp. blooms to king scallop contamination through monitoring. Indeed, P.-nitzschia was determined at the genus level and data regarding species abundances and their toxicity levels are an absolute prerequisite to further assess the environmental control of ASP events. As results describe distinct P.-nitzschia bloom dynamics along the French coast, this may suggest distinct controlling factors. They also revealed that major climatic events, such as the winter storm Xynthia in 2010, can trigger toxicity in P.-nitzschia over a large spatial scale and impact king scallop fisheries all along the coast.
Keywords	algae ; Bacillariophyceae ; coasts ; domoic acid ; fisheries ; fishery resources ; monitoring ; neurotoxins ; Pecten maximus ; phycotoxins ; phytoplankton ; scallops ; spatial variation ; storms ; toxicity ; English Channel ; France
Language	English
Dates of publication	2016-01
Size	p. 26-39.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	2091119-1
ISSN	1878-1470 ; 1568-9883
ISSN (online)	1878-1470
ISSN	1568-9883
DOI	10.1016/j.hal.2015.10.017
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Two decades of Pseudo-nitzschia spp. blooms and king scallop (Pecten maximus) contamination by domoic acid along the French Atlantic and English Channel coasts: Seasonal dynamics, spatial heterogeneity and interannual variability.

Husson, Bérengère / Hernández-Fariñas, Tania / Le Gendre, Romain / Schapira, Mathilde / Chapelle, Annie

Harmful algae

2016 Volume 51, Page(s) 26–39

Abstract	King scallop contamination (Pecten maximus) by domoic acid, a neurotoxin produced by some species of the diatom Pseudo-nitzschia, is highly problematic because of its lengthy retention in the bivalve tissue, leading to prolonged fishery closures. Data collected within the French Phytoplankton and Phycotoxin monitoring network (REPHY) over the 1995-2012 period were used to characterize the seasonal dynamics and the interannual variability of P.-nitzschia spp. blooms as well as the contamination of king scallop fishing grounds, in six contrasted bays distributed along the French Atlantic coast and English Channel. Monitoring revealed that these toxic events have become more frequent since the year 2000, but with varying magnitudes, frequencies and timing depending on the bay. Two bays, located in southern Brittany, exhibited both recurrent contaminations and high P.-nitzschia abundances. The Brest bay and the Seine bay were intermittently affected. The Pertuis Breton exhibited only one major toxic event related to an exceptionally intense bloom of P.-nitzschia in 2010, and the Saint Brieuc bay neither showed significant contamination nor high P.-nitzschia abundance. While high P.-nitzschia abundance appeared to be correlated to scallop toxicity, this study highlights the difficulty in linking P.-nitzschia spp. blooms to king scallop contamination through monitoring. Indeed, P.-nitzschia was determined at the genus level and data regarding species abundances and their toxicity levels are an absolute prerequisite to further assess the environmental control of ASP events. As results describe distinct P.-nitzschia bloom dynamics along the French coast, this may suggest distinct controlling factors. They also revealed that major climatic events, such as the winter storm Xynthia in 2010, can trigger toxicity in P.-nitzschia over a large spatial scale and impact king scallop fisheries all along the coast.
Language	English
Publishing date	2016-01
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2091119-1
ISSN	1878-1470 ; 1568-9883
ISSN (online)	1878-1470
ISSN	1568-9883
DOI	10.1016/j.hal.2015.10.017
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Article ; Online: Health Literacy and Its Associations with Understanding and Perception of Front-of-Package Nutrition Labels among Higher Education Students.

Hoge, Axelle / Labeye, Mathilde / Donneau, Anne-Françoise / Nekoee, Halehsadat Zahraei / Husson, Eddy / Guillaume, Michèle

International journal of environmental research and public health

2022 Volume 19, Issue 14

Abstract: ... 1) ... ...

Abstract	(1) Background
MeSH term(s)	Choice Behavior ; Consumer Behavior ; Food Labeling/methods ; Food Preferences ; Health Literacy ; Humans ; Nutritive Value ; Perception ; Students ; Young Adult
Language	English
Publishing date	2022-07-19
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph19148751
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Article ; Online: Patient and public involvement is suboptimal in randomized controlled trials addressing a chronic condition.

Husson, Mathilde / Dechartres, Agnès / Ramdjee, Bruno / Diverres, Maëlle / Zejli, Tarik / L'Hénaff, Marianne / Jehanno, Eric / Tubach, Florence / Caille, Agnès

Journal of clinical epidemiology

2023 Volume 160, Page(s) 71–82

Abstract: Objectives: To describe patient and public involvement (PPI) in randomized controlled trials (RCTs) addressing a chronic condition and to analyze whether PPI is associated with trial characteristics.: Study design and setting: We used PubMed search ... ...

Abstract	Objectives: To describe patient and public involvement (PPI) in randomized controlled trials (RCTs) addressing a chronic condition and to analyze whether PPI is associated with trial characteristics. Study design and setting: We used PubMed search to identify RCTs addressing a chronic condition and published in journals with a mandatory PPI statement. Results: Across 101 RCTs; 40 (40%) reported PPI at any stage of the research process. PPI contribution occurred mostly at the design stage of RCTs (n = 36), especially for assessing the burden of the intervention (n = 24), and at the conduct stage (n = 21), with the elaboration of communication materials (n = 14). Less than one-third (13/40) of RCTs included PPI in the development or choice of outcome measures. As compared with non-PPI RCTs, PPI RCTs more frequently were published in The BMJ, had a corresponding author from the United Kingdom, reported a public funding source, had a higher inclusion rate, used usual care as a control and evaluated a digital intervention. PPI RCTs were associated with less frequent use of placebo as a control group. Conclusion: Our results underline that PPI is not uncommon in RCTs of chronic conditions but infrequently occurred at a key stage. Yet, the engagement of patients as a real partner in RCTs of chronic conditions should be enhanced.
MeSH term(s)	Humans ; Randomized Controlled Trials as Topic ; Chronic Disease ; Patient Participation ; Outcome Assessment, Health Care ; United Kingdom
Language	English
Publishing date	2023-06-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	639306-8
ISSN	1878-5921 ; 0895-4356
ISSN (online)	1878-5921
ISSN	0895-4356
DOI	10.1016/j.jclinepi.2023.06.012
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Article: Identification of High Likelihood of Dementia in Population-Based Surveys using Unsupervised Clustering: a Longitudinal Analysis.

Gharbi-Meliani, Amin / Husson, François / Vandendriessche, Henri / Eleonore Bayen, France / Yaffe, Kristine / Bachoud-Lévi, Anne-Catherine / de Langavant, Laurent Cleret

medRxiv : the preprint server for health sciences

2023

Abstract: Background: Dementia is defined by cognitive decline that affects functional status. Longitudinal ageing surveys often lack a clinical diagnosis of dementia though measure cognitive and function over time. We used unsupervised machine learning and ... ...

Abstract	Background: Dementia is defined by cognitive decline that affects functional status. Longitudinal ageing surveys often lack a clinical diagnosis of dementia though measure cognitive and function over time. We used unsupervised machine learning and longitudinal data to identify transition to probable dementia. Methods: Multiple Factor Analysis was applied to longitudinal function and cognitive data of 15,278 baseline participants (aged 50 years and more) from the Survey of Health, Ageing, and Retirement in Europe (SHARE) (waves 1, 2 and 4-7, between 2004 and 2017). Hierarchical Clustering on Principal Components discriminated three clusters at each wave. We estimated probable or "Likely Dementia" prevalence by sex and age, and assessed whether dementia risk factors increased the risk of being assigned probable dementia status using multistate models. Next, we compared the "Likely Dementia" cluster with self-reported dementia status and replicated our findings in the English Longitudinal Study of Ageing (ELSA) cohort (waves 1-9, between 2002 and 2019, 7,840 participants at baseline). Findings: Our algorithm identified a higher number of probable dementia cases compared with self-reported cases and showed good discriminative power across all waves (AUC ranged from 0.754 [0.722-0.787] to 0.830 [0.800-0.861]). "Likely Dementia" status was more prevalent in older people, displayed a 2:1 female/male ratio and was associated with nine factors that increased risk of transition to dementia: low education, hearing loss, hypertension, drinking, smoking, depression, social isolation, physical inactivity, diabetes, and obesity. Results were replicated in ELSA cohort with good accuracy. Interpretation: Machine learning clustering can be used to study dementia determinants and outcomes in longitudinal population ageing surveys in which dementia clinical diagnosis is lacking.
Language	English
Publishing date	2023-02-23
Publishing country	United States
Document type	Preprint
DOI	10.1101/2023.02.17.23286078
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Article ; Online: Identification of high likelihood of dementia in population-based surveys using unsupervised clustering: a longitudinal analysis.

Gharbi-Meliani, Amin / Husson, François / Vandendriessche, Henri / Bayen, Eleonore / Yaffe, Kristine / Bachoud-Lévi, Anne-Catherine / Cleret de Langavant, Laurent

Alzheimer's research & therapy

2023 Volume 15, Issue 1, Page(s) 209

Abstract: Background: Dementia is defined as a cognitive decline that affects functional status. Longitudinal ageing surveys often lack a clinical diagnosis of dementia though measure cognition and daily function over time. We used unsupervised machine learning ... ...

Abstract	Background: Dementia is defined as a cognitive decline that affects functional status. Longitudinal ageing surveys often lack a clinical diagnosis of dementia though measure cognition and daily function over time. We used unsupervised machine learning and longitudinal data to identify transition to probable dementia. Methods: Multiple Factor Analysis was applied to longitudinal function and cognitive data of 15,278 baseline participants (aged 50 years and more) from the Survey of Health, Ageing, and Retirement in Europe (SHARE) (waves 1, 2 and 4-7, between 2004 and 2017). Hierarchical Clustering on Principal Components discriminated three clusters at each wave. We estimated probable or "Likely Dementia" prevalence by sex and age, and assessed whether dementia risk factors increased the risk of being assigned probable dementia status using multistate models. Next, we compared the "Likely Dementia" cluster with self-reported dementia status and replicated our findings in the English Longitudinal Study of Ageing (ELSA) cohort (waves 1-9, between 2002 and 2019, 7840 participants at baseline). Results: Our algorithm identified a higher number of probable dementia cases compared with self-reported cases and showed good discriminative power across all waves (AUC ranged from 0.754 [0.722-0.787] to 0.830 [0.800-0.861]). "Likely Dementia" status was more prevalent in older people, displayed a 2:1 female/male ratio, and was associated with nine factors that increased risk of transition to dementia: low education, hearing loss, hypertension, drinking, smoking, depression, social isolation, physical inactivity, diabetes, and obesity. Results were replicated in ELSA cohort with good accuracy. Conclusions: Machine learning clustering can be used to study dementia determinants and outcomes in longitudinal population ageing surveys in which dementia clinical diagnosis is lacking.
MeSH term(s)	Humans ; Male ; Female ; Middle Aged ; Aged ; Longitudinal Studies ; Aging/psychology ; Cognitive Dysfunction/diagnosis ; Cognition ; Dementia/epidemiology ; Dementia/diagnosis
Language	English
Publishing date	2023-11-29
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
ZDB-ID	2506521-X
ISSN	1758-9193 ; 1758-9193
ISSN (online)	1758-9193
ISSN	1758-9193
DOI	10.1186/s13195-023-01357-9
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Article ; Online: 24 années d’épidémie de sida dans l’archipel indonésien

Laurence Husson

Moussons, Iss 15, Pp 201-

2012 Volume 208

Abstract: ... à 33 millions, avec 2,7 millions de nouvelles contaminations et 2 millions de décès dans l’année. Si l ...

Abstract	L’ONUSIDA dans son bilan 2007 estimait le nombre de personnes infectées par le VIH dans le monde à 33 millions, avec 2,7 millions de nouvelles contaminations et 2 millions de décès dans l’année. Si l’Afrique subsaharienne était de loin la région du monde la plus durement touchée avec 22 millions de personnes infectées, l’Asie du Sud et du Sud-Est était aussi très concernée avec 4,2 millions de personnes porteuses du virus. Au sein de cette Asie, l’Indonésie, avec 240 millions d’habitants en 2.
Keywords	History of Asia ; DS1-937 ; Social Sciences ; H
Language	English
Publishing date	2012-10-01T00:00:00Z
Publisher	Université de Provence
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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