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  1. Article ; Online: Post Kala-azar Dermal Leishmaniasis.

    Das, Nilay Kanti

    Indian journal of dermatology

    2020  Volume 65, Issue 6, Page(s) 450–451

    Language English
    Publishing date 2020-11-01
    Publishing country India
    Document type Editorial
    ZDB-ID 416069-1
    ISSN 1998-3611 ; 0019-5154
    ISSN (online) 1998-3611
    ISSN 0019-5154
    DOI 10.4103/ijd.IJD_439_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Symmetric drug-related intertriginous and flexural exanthema due to super-bioavailable itraconazole.

    Dhabal, Arunima / Das, Nilay Kanti / Sil, Amrita

    Indian journal of pharmacology

    2023  Volume 55, Issue 3, Page(s) 192–193

    MeSH term(s) Humans ; Itraconazole/adverse effects ; Exanthema/chemically induced ; Drug Eruptions/etiology
    Chemical Substances Itraconazole (304NUG5GF4)
    Language English
    Publishing date 2023-08-09
    Publishing country India
    Document type Letter
    ZDB-ID 605829-2
    ISSN 1998-3751 ; 0253-7613
    ISSN (online) 1998-3751
    ISSN 0253-7613
    DOI 10.4103/ijp.ijp_102_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Ethical Issues Pertinent to Current Clinical Research Environment in India.

    Das, Nilay Kanti

    Indian journal of dermatology

    2017  Volume 62, Issue 4, Page(s) 371–372

    Language English
    Publishing date 2017-07
    Publishing country India
    Document type Editorial
    ZDB-ID 416069-1
    ISSN 1998-3611 ; 0019-5154
    ISSN (online) 1998-3611
    ISSN 0019-5154
    DOI 10.4103/ijd.IJD_270_17
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  4. Article ; Online: Ethical issues pertinent to current clinical research environment in India

    Nilay Kanti Das

    Indian Journal of Dermatology, Vol 62, Iss 4, Pp 371-

    2017  Volume 372

    Keywords Medicine ; R ; Dermatology ; RL1-803
    Language English
    Publishing date 2017-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Post Kala-Azar Dermal Leishmaniasis: Clinical Features and Differential Diagnosis.

    Kumar, Piyush / Chatterjee, Mitali / Das, Nilay Kanti

    Indian journal of dermatology

    2021  Volume 66, Issue 1, Page(s) 24–33

    Abstract: Post kala-azar dermal leishmaniasis (PKDL) is a mucocutaneous disease usually seen in apparently cured, inadequately treated or untreated cases of visceral leishmaniasis and is endemic to many parts of India, Nepal, Bangladesh, and eastern Africa (Sudan, ...

    Abstract Post kala-azar dermal leishmaniasis (PKDL) is a mucocutaneous disease usually seen in apparently cured, inadequately treated or untreated cases of visceral leishmaniasis and is endemic to many parts of India, Nepal, Bangladesh, and eastern Africa (Sudan, Ethiopia, Kenya). The disease usually manifests as a variable combination of hypopigmented patches, erythematous succulent papulo-plaques, and nodular lesions on the face and upper body and sometimes extending on the extremities, genitalia, and tongue. Atypical morphology and presentations are not uncommon, especially in endemic areas, which include photosensitivity, verrucous, hypertrophic, xanthomatous, and ulcerative lesions. Recognition of spectrum of mucocutaneous changes helps physicians in early initiation of treatment and in reducing disease transmission in the community. The differential diagnosis depends on the pattern of manifestations, but lepromatous leprosy is the closest mimicker. Since PKDL does not cause significant morbidity, at least initially, but the affected patients continue to act as a reservoir of the disease, active case detection is required to identify cases early to control the disease transmission in the community.
    Language English
    Publishing date 2021-04-28
    Publishing country India
    Document type Journal Article
    ZDB-ID 416069-1
    ISSN 1998-3611 ; 0019-5154
    ISSN (online) 1998-3611
    ISSN 0019-5154
    DOI 10.4103/ijd.IJD_602_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: P

    Sil, Amrita / Betkerur, Jayadev / Das, Nilay Kanti

    Indian dermatology online journal

    2019  Volume 10, Issue 6, Page(s) 745–750

    Abstract: Biomedical research relies on proving (or disproving) a research hypothesis, ... ...

    Abstract Biomedical research relies on proving (or disproving) a research hypothesis, and
    Language English
    Publishing date 2019-11-01
    Publishing country India
    Document type Journal Article
    ZDB-ID 2585814-2
    ISSN 2249-5673 ; 2229-5178
    ISSN (online) 2249-5673
    ISSN 2229-5178
    DOI 10.4103/idoj.IDOJ_368_19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Does immune dysregulation contribute towards development of hypopigmentation in Indian post kala-azar dermal leishmaniasis?

    Sengupta, Ritika / Mitra, Sneha / Dighal, Aishwarya / Moulik, Srija / Chaudhuri, Surya Jyati / Das, Nilay Kanti / Chatterjee, Uttara / Chatterjee, Mitali

    Experimental dermatology

    2023  Volume 32, Issue 6, Page(s) 740–751

    Abstract: Post kala-azar dermal leishmaniasis (PKDL), a sequel of apparently cured visceral leishmaniasis (VL) presents with papulonodular (polymorphic) or hypopigmented lesions (macular) and is the proposed disease reservoir. As hypopigmentation appears ... ...

    Abstract Post kala-azar dermal leishmaniasis (PKDL), a sequel of apparently cured visceral leishmaniasis (VL) presents with papulonodular (polymorphic) or hypopigmented lesions (macular) and is the proposed disease reservoir. As hypopigmentation appears consistently in PKDL, especially the macular form, this study aimed to delineate immune factors that singly or in combination could contribute towards this hypopigmentation. At lesional sites, the presence of melanocytes and CD8
    MeSH term(s) Humans ; Leishmaniasis, Visceral/complications ; Leishmaniasis, Visceral/pathology ; Leishmania donovani ; MART-1 Antigen ; CD8-Positive T-Lymphocytes ; Interleukin-6 ; Tumor Necrosis Factor-alpha ; Interleukin-2 ; Leishmaniasis, Cutaneous ; Hypopigmentation
    Chemical Substances MART-1 Antigen ; Interleukin-6 ; Tumor Necrosis Factor-alpha ; Interleukin-2
    Language English
    Publishing date 2023-02-20
    Publishing country Denmark
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1130936-2
    ISSN 1600-0625 ; 0906-6705
    ISSN (online) 1600-0625
    ISSN 0906-6705
    DOI 10.1111/exd.14760
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Epidemiology of Post-Kala-azar Dermal Leishmaniasis.

    Ghosh, Pramit / Roy, Pritam / Chaudhuri, Surya Jyati / Das, Nilay Kanti

    Indian journal of dermatology

    2021  Volume 66, Issue 1, Page(s) 12–23

    Abstract: Post-kala-azar dermal leishmaniasis (PKDL) is a cutaneous sequel of visceral leishmaniasis (VL) or kala-azar and has become an entity of epidemiological significance by virtue of its ability to maintain the disease in circulation during inter-epidemic ... ...

    Abstract Post-kala-azar dermal leishmaniasis (PKDL) is a cutaneous sequel of visceral leishmaniasis (VL) or kala-azar and has become an entity of epidemiological significance by virtue of its ability to maintain the disease in circulation during inter-epidemic periods. PKDL has been identified as one of the epidemiological marker of "kala-azar elimination programme." Data obtained in 2018 showed PKDL distribution primarily concentrated in 6 countries, which includes India, Sudan, south Sudan, Bangladesh, Ethiopia, and Nepal in decreasing order of case-burden. In India, PKDL cases are mainly found in 54 districts, of which 33 are in Bihar, 11 in West Bengal, 4 in Jharkhand, and 6 in Uttar Pradesh. In West Bengal the districts reporting cases of PKDL cases include Darjeeling, Uttar Dinajpur, Dakshin Dinajpur, Malda, and Murshidabad. The vulnerability on the young age is documented in various studies. The studies also highlights a male predominance of the disease but recent active surveillance suggested that macular form of PKDL shows female-predominance. It is recommended that along with passive case detection, active survey helps in early identification of cases, thus reducing disease transmission in the community. The
    Language English
    Publishing date 2021-04-28
    Publishing country India
    Document type Journal Article
    ZDB-ID 416069-1
    ISSN 1998-3611 ; 0019-5154
    ISSN (online) 1998-3611
    ISSN 0019-5154
    DOI 10.4103/ijd.IJD_651_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Implementation of National Leprosy Eradication Programme during COVID-19 era: A qualitative research.

    Bhattacharya, Tridibes / Das, Somenath / Sarkar, Aditya Prasad / Patra, Aparesh Chandra / Sarkar, Debajit / Das, Nilay Kanti

    Indian journal of dermatology, venereology and leprology

    2022  Volume 89, Issue 3, Page(s) 393–402

    Abstract: Introduction The COVID-19 pandemic imposed new challenge to the implementation of the National Leprosy Eradication Programme. According to national data, after lockdown due to COVID-19, there was a 29% reduction in total leprosy cases reported in the ... ...

    Abstract Introduction The COVID-19 pandemic imposed new challenge to the implementation of the National Leprosy Eradication Programme. According to national data, after lockdown due to COVID-19, there was a 29% reduction in total leprosy cases reported in the first quarter (April-June) of 2020 in comparison to 2019. Objectives To explore the difficulties faced by different stakeholders of the National Leprosy Eradication Programme like policy makers, doctors, grass root level health workers as well as leprosy patients during COVID-19 pandemic with respect to programme implementation and access to leprosy care. Materials and Methods Qualitative research was undertaken including two focus-group-discussions held among six leprosy patients diagnosed after lockdown and nine ASHA workers as well as six in-depth interviews of doctors, leprologists, and programme managers. Ethics committee approval was sought and informed consent was obtained from all participants. All focus-group-discussions were electronically recorded and the in-depth interviews telephonically recorded, transcribed and translated from Bengali-to-English. Transcripts were separately coded by researchers and thematically analysed with the help of Visual-Anthropac software version 1.0. Results Solitary focus on COVID-19 control, capacity building and information, education and communication, leprosy case search & surveillance, co-infection among health workers, transportation issues were the themes explored from focus-group-discussions of health workers and ASHA workers. Similarly, the present study identified six themes from in-depth interviews of programme manager, leprologists, programme manager as diagnostic difficulty, operational issues, rehabilitation issues, capacity building & information education and communication activities and way forward. Limitations The research reveals the perceptions of rural population of Eastern India with high leprosy prevalence, which might not be applicable for urban areas or low prevalent districts Conclusion The solitary focus of the administration towards COVID and shifting the infrastructure and human resource only towards the management of COVID can lead to resurgence of the leprosy. Having an organised framework of operations, catering to the need of the front-line workers in rendering services, utilizing the digital platform and social media, and focusing on rehabilitation would be needed to overcome the crisis.
    MeSH term(s) Humans ; COVID-19/epidemiology ; COVID-19/prevention & control ; Pandemics/prevention & control ; Communicable Disease Control ; Qualitative Research ; Leprosy/diagnosis ; Leprosy/epidemiology ; Leprosy/prevention & control
    Language English
    Publishing date 2022-11-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 416068-x
    ISSN 0973-3922 ; 0019-5162 ; 0378-6323
    ISSN (online) 0973-3922
    ISSN 0019-5162 ; 0378-6323
    DOI 10.25259/IJDVL_469_2021
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  10. Article ; Online: Cyclosporine in toxic epidermal necrolysis: a brief review of the emerging therapeutic modality.

    Kumar, Piyush / Kanti Das, Nilay

    Dermatology online journal

    2016  Volume 22, Issue 10

    Abstract: Toxic epidermal necrolysis (TEN) is a severe life-threatening adverse drug reaction that predominantly involve the skin and mucous membranes, and is associated with high mortality (25-35% or even higher) and with various long term sequelae. There is no ... ...

    Abstract Toxic epidermal necrolysis (TEN) is a severe life-threatening adverse drug reaction that predominantly involve the skin and mucous membranes, and is associated with high mortality (25-35% or even higher) and with various long term sequelae. There is no universally accepted treatment for TEN, but key elements of management include rapid diagnosis, identification and interruption of the culprit drug, evaluation of the prognosis using SCORTEN, specialized supportive care ideally in an intensive care unit, and consideration of immunomodulating agents. Cyclosporine has recently emerged as a promising immunomodulating agent in the management of TEN and we have performed a brief review of evidence highlighting its role in TEN management.
    MeSH term(s) Cyclosporine/therapeutic use ; Humans ; Immunosuppressive Agents/therapeutic use ; Stevens-Johnson Syndrome/drug therapy ; Stevens-Johnson Syndrome/immunology ; Stevens-Johnson Syndrome/mortality
    Chemical Substances Immunosuppressive Agents ; Cyclosporine (83HN0GTJ6D)
    Language English
    Publishing date 2016-10-15
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2026239-5
    ISSN 1087-2108 ; 1087-2108
    ISSN (online) 1087-2108
    ISSN 1087-2108
    Database MEDical Literature Analysis and Retrieval System OnLINE

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