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  1. Article ; Online: The Death of George Floyd: Bending the Arc of History Toward Justice for Generations of Children.

    Dreyer, Benard P / Trent, Maria / Anderson, Ashaunta T / Askew, George L / Boyd, Rhea / Coker, Tumaini R / Coyne-Beasley, Tamera / Fuentes-Afflick, Elena / Johnson, Tiffani / Mendoza, Fernando / Montoya-Williams, Diana / Oyeku, Suzette O / Poitevien, Patricia / Spinks-Franklin, Adiaha A I / Thomas, Olivia W / Walker-Harding, Leslie / Willis, Earnestine / Wright, Joseph L / Berman, Stephen /
    Berkelhamer, Jay / Jenkins, Renee R / Kraft, Colleen / Palfrey, Judith / Perrin, James M / Stein, Fernando

    Pediatrics

    2020  Volume 146, Issue 3

    MeSH term(s) Adolescent ; Advisory Committees/organization & administration ; African Americans/history ; Child ; Child Welfare ; Congresses as Topic ; History, 20th Century ; History, 21st Century ; Homicide/history ; Humans ; Law Enforcement/methods ; Pediatrics ; Physician's Role ; Police/education ; Police/organization & administration ; Racism/prevention & control ; Racism/psychology ; Social Discrimination ; Social Justice ; United States ; Video Recording ; Whistleblowing
    Keywords covid19
    Language English
    Publishing date 2020-06-26
    Publishing country United States
    Document type Biography ; Historical Article ; Journal Article
    ZDB-ID 207677-9
    ISSN 1098-4275 ; 0031-4005
    ISSN (online) 1098-4275
    ISSN 0031-4005
    DOI 10.1542/peds.2020-009639
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book: A companion to George Eliot

    Anderson, Amanda / Eliot, George / Shaw, Harry E

    (Blackwell companions to literature and culture ; 82)

    2013  

    Title variant George Eliot
    Author's details ed. by Amanda Anderson and Harry E. Shaw
    Series title Blackwell companions to literature and culture ; 82
    Language English
    Size XIII, 517 S., Ill.
    Publisher Wiley-Blackwell
    Publishing place Malden, Mass. u.a.
    Document type Book
    Note Includes bibliographical references and index
    ISBN 0470655992 ; 9780470655993 ; 9781118542354 ; 1118542355
    Database Former special subject collection: coastal and deep sea fishing

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  3. Book: A companion to George Eliot

    Anderson, Amanda / Eliot, George / Shaw, Harry E

    (Blackwell companions to literature and culture ; 82)

    2013  

    Title variant George Eliot
    Author's details ed. by Amanda Anderson and Harry E. Shaw
    Series title Blackwell companions to literature and culture ; 82
    Language English
    Size XIII, 517 S., Ill.
    Publisher Wiley-Blackwell
    Publishing place Malden, Mass. u.a.
    Document type Book
    Note Includes bibliographical references and index
    ISBN 0470655992 ; 9780470655993 ; 9781118542354 ; 1118542355
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  4. Article ; Online: A tribute to Dr. George Zarb.

    Anderson, Jim

    Journal (Canadian Dental Association)

    2005  Volume 71, Issue 5, Page(s) 325

    MeSH term(s) Canada ; History, 20th Century ; History, 21st Century ; Prosthodontics/history
    Language English
    Publishing date 2005-05
    Publishing country Canada
    Document type Biography ; Historical Article
    ZDB-ID 604786-5
    ISSN 1488-2159 ; 0709-8936 ; 0008-3372
    ISSN (online) 1488-2159
    ISSN 0709-8936 ; 0008-3372
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Genome sequence of Exiguobacterium antarcticum B7, isolated from a biofilm in Ginger Lake, King George Island, Antarctica.

    Carneiro, Adriana Ribeiro / Ramos, Rommel Thiago Jucá / Dall'Agnol, Hivana / Pinto, Anne Cybelle / de Castro Soares, Siomar / Santos, Anderson Rodrigues / Guimarães, Luis Carlos / Almeida, Sintia Silva / Baraúna, Rafael Azevedo / das Graças, Diego Assis / Franco, Luciano Chaves / Ali, Amjad / Hassan, Syed Shah / Nunes, Catarina Isabel P / Barbosa, Maria Silvanira / Fiaux, Karina Kelly / Aburjaile, Flávia Figueira / Barbosa, Eudes Guilherme Vieira / Bakhtiar, Syeda Marriam /
    Vilela, Daniella / Nóbrega, Felipe / dos Santos, Adriana Lopes / Carepo, Marta Sofia P / Azevedo, Vasco / Schneider, Maria Paula Cruz / Pellizari, Vivian Helena / Silva, Artur

    Journal of bacteriology

    2012  Volume 194, Issue 23, Page(s) 6689–6690

    Abstract: ... of E. antarcticum B7, isolated from a biofilm sample of Ginger Lake on King George Island, Antarctic ...

    Abstract Exiguobacterium antarcticum is a psychotropic bacterium isolated for the first time from microbial mats of Lake Fryxell in Antarctica. Many organisms of the genus Exiguobacterium are extremophiles and have properties of biotechnological interest, e.g., the capacity to adapt to cold, which make this genus a target for discovering new enzymes, such as lipases and proteases, in addition to improving our understanding of the mechanisms of adaptation and survival at low temperatures. This study presents the genome of E. antarcticum B7, isolated from a biofilm sample of Ginger Lake on King George Island, Antarctic peninsula.
    MeSH term(s) Antarctic Regions ; Bacillales/genetics ; Bacillales/isolation & purification ; Bacillales/physiology ; Biofilms/growth & development ; DNA, Bacterial/chemistry ; DNA, Bacterial/genetics ; Fresh Water/microbiology ; Genome, Bacterial ; Islands ; Lakes ; Molecular Sequence Data ; Sequence Analysis, DNA
    Chemical Substances DNA, Bacterial
    Language English
    Publishing date 2012-11-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2968-3
    ISSN 1098-5530 ; 0021-9193
    ISSN (online) 1098-5530
    ISSN 0021-9193
    DOI 10.1128/JB.01791-12
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Heiser, Victor George

    Anderson, Warwick

    American national biography v.10

    1999  

    Author's details Warwick Anderson
    MeSH term(s) Physicians ; Public Health Administration ; History of Medicine ; History, 19th Century ; History, 20th Century
    Keywords United States
    Language English
    Size p. 522-524.
    Publisher Oxford University Press
    Publishing place New York
    Document type Article
    ISBN 0195206355 ; 9780195206357
    Database Catalogue of the US National Library of Medicine (NLM)

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  7. Article: Genome Sequence of Exiguobacterium antarcticum B7, Isolated from a Biofilm in Ginger Lake, King George Island, Antarctica

    Carneiro, Adriana Ribeiro / Ramos, Rommel Thiago Jucá / Dall'Agnol, Hivana / Pinto, Anne Cybelle / de Castro Soares, Siomar / Santos, Anderson Rodrigues / Guimarães, Luis Carlos / Almeida, Sintia Silva / Baraúna, Rafael Azevedo / das Graças, Diego Assis / Franco, Luciano Chaves / Ali, Amjad / Hassan, Syed Shah / Nunes, Catarina Isabel P / Barbosa, Maria Silvanira / Fiaux, Karina Kelly / Aburjaile, Flávia Figueira / Barbosa, Eudes Guilherme Vieira / Bakhtiar, Syeda Marriam /
    Vilela, Daniella / Nóbrega, Felipe / dos Santos, Adriana Lopes / Carepo, Marta Sofia P / Azevedo, Vasco / Schneider, Maria Paula Cruz / Pellizari, Vivian Helena / Silva, Artur

    Journal of bacteriology. 2012 Dec. 1, v. 194, no. 23

    2012  

    Abstract: ... of E. antarcticum B7, isolated from a biofilm sample of Ginger Lake on King George Island, Antarctic ...

    Abstract Exiguobacterium antarcticum is a psychotropic bacterium isolated for the first time from microbial mats of Lake Fryxell in Antarctica. Many organisms of the genus Exiguobacterium are extremophiles and have properties of biotechnological interest, e.g., the capacity to adapt to cold, which make this genus a target for discovering new enzymes, such as lipases and proteases, in addition to improving our understanding of the mechanisms of adaptation and survival at low temperatures. This study presents the genome of E. antarcticum B7, isolated from a biofilm sample of Ginger Lake on King George Island, Antarctic peninsula.
    Keywords Exiguobacterium ; bacteria ; biofilm ; cold ; extremophiles ; genome ; lakes ; nucleotide sequences ; proteinases ; temperature ; triacylglycerol lipase ; Antarctic region ; Antarctica
    Language English
    Dates of publication 2012-1201
    Size p. 6689-6690.
    Publishing place American Society for Microbiology
    Document type Article
    ZDB-ID 2968-3
    ISSN 1098-5530 ; 0021-9193
    ISSN (online) 1098-5530
    ISSN 0021-9193
    DOI 10.1128/JB.01791-12
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: A More Holistic Perspective of Alzheimer's Disease: Roles of Gut Microbiome, Adipocytes, HPA Axis, Melatonergic Pathway and Astrocyte Mitochondria in the Emergence of Autoimmunity.

    Anderson, George

    Frontiers in bioscience (Landmark edition)

    2024  Volume 28, Issue 12, Page(s) 355

    Abstract: Alzheimer's disease is widely regarded as poorly treated due to poor conceptualization. For 40 years, Alzheimer's disease pathophysiology has focused on two culprits, amyloid-β induced plaques and hyperphosphorylated tau associated tangles, with no ... ...

    Abstract Alzheimer's disease is widely regarded as poorly treated due to poor conceptualization. For 40 years, Alzheimer's disease pathophysiology has focused on two culprits, amyloid-β induced plaques and hyperphosphorylated tau associated tangles, with no significant treatment advance. This is confounded by data showing amyloid-β to be an endogenous antimicrobial that is increased in a wide array of diverse medical conditions associated with heightened inflammation. This article reviews the wider bodies of data pertaining to Alzheimer's disease pathophysiology, highlighting the role of suppressed astrocyte mitochondrial function and mitochondrial melatonergic pathway as a core hub in driving neuronal loss in dementia. It is proposed that astrocyte function over aging becomes dysregulated, at least partly mediated by systemic processes involving the 10-fold decrease in pineal melatonin leading to the attenuated capacity of night-time melatonin to dampen residual daytime inflammation. Suppressed pineal melatonin also attenuates melatonin's inhibition of glucocorticoid receptor nuclear translocation, thereby changing not only stress/hypothalamus-pituitary-adrenal (HPA) axis consequences but also the consequences of the cortisol awakening response, which 'primes the body for the coming day'. Gut microbiome-derived butyrate also inhibits glucocorticoid receptor nuclear translocation, as well as inducing the mitochondrial melatonergic pathway. It is proposed that the loss of astrocyte melatonin prevents the autocrine and paracrine effects of melatonin in limiting amyloid-β levels and effects. Suppressed astrocyte melatonin production also attenuates the melatonin induction of astrocyte lactate, thereby decreasing neuronal mitochondrial metabolism and the neuronal mitochondrial melatonergic pathway. The loss of astrocyte lactate and melatonin, coupled to the suppression of neuronal mitochondrial metabolism and melatonin production decreases mitophagy, leading to the induction of the major histocompatibility complex (MHC)-1. MHC-1 initiates the chemoattraction of CD8+ t cells, leading to neuronal destruction in Alzheimer's disease being driven by 'autoimmune'/'immune-mediated' processes. Alzheimer's disease may therefore be conceptualized as being initiated by systemic processes that act on astrocytes as a core hub, with the suppression of the astrocyte melatonergic pathway leaving neurons deplete of appropriate metabolic substrates and co-ordinated antioxidants. This culminates in an 'immune-mediated' cell death. Future research and treatment/prevention implications are indicated.
    MeSH term(s) Humans ; Astrocytes/metabolism ; Melatonin/metabolism ; Alzheimer Disease/metabolism ; Autoimmunity ; Gastrointestinal Microbiome ; Hypothalamo-Hypophyseal System/metabolism ; Receptors, Glucocorticoid/metabolism ; Pituitary-Adrenal System/metabolism ; Inflammation/metabolism ; Mitochondria/metabolism ; Adipocytes/metabolism ; Lactates/metabolism
    Chemical Substances Melatonin (JL5DK93RCL) ; Receptors, Glucocorticoid ; Lactates
    Language English
    Publishing date 2024-01-16
    Publishing country Singapore
    Document type Journal Article ; Review
    ZDB-ID 2704569-9
    ISSN 2768-6698 ; 2768-6698
    ISSN (online) 2768-6698
    ISSN 2768-6698
    DOI 10.31083/j.fbl2812355
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Polycystic Ovary Syndrome Pathophysiology: Integrating Systemic, CNS and Circadian Processes.

    Anderson, George

    Frontiers in bioscience (Landmark edition)

    2024  Volume 29, Issue 1, Page(s) 24

    Abstract: The conceptualization of polycystic ovary syndrome (PCOS) has primarily focused on hormonal alterations driven by changes within the hypothalamus and ovarian granulosa cells, with treatment by the contraceptive pill and weight loss. However, a growing ... ...

    Abstract The conceptualization of polycystic ovary syndrome (PCOS) has primarily focused on hormonal alterations driven by changes within the hypothalamus and ovarian granulosa cells, with treatment by the contraceptive pill and weight loss. However, a growing body of data implicates wider systemic and central nervous system (CNS) changes in the pathoetiology and pathophysiology of PCOS, with consequent implications for targeted treatments. It is proposed that there is a significant role for night-time interactions of factors acting to regulate whether the rising level of cortisol over the night and during the morning cortisol awakening response (CAR) is able to induce the nuclear translocation of the glucocorticoid receptor (GR), thereby influencing how the immune and glial systems regulate cellular function in preparation for the coming day. Factors affording protection in PCOS also inhibit GR nuclear translocation including gut microbiome-derived butyrate, and pineal/local melatonin as well as melatonin regulated bcl2-associated athanogene (BAG)-1. A significant pathophysiological role in PCOS is attributed to the aryl hydrocarbon receptor (AhR), which shows heightened levels and activity in PCOS. The AhR is activated by ligands of many systemic processes, including white adipocyte-derived kynurenine, implicating obesity in the pathophysiological changes occurring in the hypothalamus and ovaries. AhR activation has consequences for the physiological function in the hypothalamic paraventricular nucleus, granulosa cells and adipocytes, partly mediated by AhR upregulation of the mitochondrial N-acetylserotonin/melatonin ratio, thereby decreasing melatonin availability whilst increasing local stress plasticity in the paraventricular nucleus. This article reviews in detail the wider systemic and CNS changes in PCOS highlighting interactions of local and pineal melatonergic pathway, gut microbiome-derived butyrate, white adipocyte-derived kynurenine, the hypothalamic paraventricular nucleus tanycytes/astrocytes, and the hypothalamus-pituitary-adrenal (HPA) axis driven glucocorticoid receptor activation in PCOS pathophysiology. This integrates a wide array of previously disparate data on the biological underpinnings of PCOS, including how PCOS associates with many other currently classified medical conditions, such as depression, bipolar disorder, type 1 diabetes mellitus and the autism spectrum. Numerous future research and treatment implications are detailed.
    MeSH term(s) Female ; Humans ; Melatonin/metabolism ; Polycystic Ovary Syndrome ; Hydrocortisone ; Kynurenine ; Receptors, Glucocorticoid/metabolism ; Central Nervous System/metabolism ; Butyrates
    Chemical Substances Melatonin (JL5DK93RCL) ; Hydrocortisone (WI4X0X7BPJ) ; Kynurenine (343-65-7) ; Receptors, Glucocorticoid ; Butyrates
    Language English
    Publishing date 2024-02-10
    Publishing country Singapore
    Document type Journal Article ; Review
    ZDB-ID 2704569-9
    ISSN 2768-6698 ; 2768-6698
    ISSN (online) 2768-6698
    ISSN 2768-6698
    DOI 10.31083/j.fbl2901024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Remarks on the Remedial Virtues of Cannabis Indica, or Indian Hemp.

    Anderson, George S D

    Western journal of medicine and surgery

    2024  Volume 4, Issue 12, Page(s) 426–430

    Language English
    Publishing date 2024-01-11
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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