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Article ; Online: A large-scale group decision making method to select the ideal mobile health application for the hospital.

Zhang, Xumin / Meng, Fanyong

Applied intelligence (Dordrecht, Netherlands)

2022 Volume 52, Issue 14, Page(s) 15844–15864

Abstract: Mobile health, which is not limited by time and space, can effectively alleviate the imbalance of medical resources. Currently, more and more hospitals begin to pay attention to online medical care and actively expand their mobile channels. Among of ... ...

Abstract	Mobile health, which is not limited by time and space, can effectively alleviate the imbalance of medical resources. Currently, more and more hospitals begin to pay attention to online medical care and actively expand their mobile channels. Among of which, the cooperation with the third-party platform is an effective way to expand the online services of most hospitals. With the increasing number of mobile health applications (mHealth apps), it is difficult to select the ideal application. Most of the existing studies on mHealth app selection are conducted from the perspective of users who have health needs, which is insufficient. The views of multiple stakeholders should be taken into account. mHealth app selection can be regarded as a large-scale group decision making (LSGDM) problem. In this paper, a hybrid LSGDM method is proposed to select the mHealth app with the highest user satisfaction. First, the weights of criteria are obtained based on quality function deployment and 2-additive measure. Furthermore, a consensus model that considers cooperative and non-cooperative behaviors of decision makers is applied to select the ideal mHealth app. Finally, an illustrative example is implemented to exhibit the utility and validity of the proposed model.
Language	English
Publishing date	2022-03-18
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1479519-X
ISSN	1573-7497 ; 0924-669X
ISSN (online)	1573-7497
ISSN	0924-669X
DOI	10.1007/s10489-022-03273-1
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Role of PPARG in Chemosensitivity-Regulating Network for Hypopharyngeal Squamous Cell Carcinoma.

Kong, Fanyong / Han, Boxuan / Chen, Jiaming / Shen, Xixi / Hou, Lizhen / Fang, Jugao / Lian, Meng

PPAR research

2023 Volume 2023, Page(s) 6019318

Abstract: PPARG has been reported to promote chemosensitivity in hypopharyngeal squamous cell carcinoma (HSCC). However, few studies tested its significance in the texture of a complex molecular network regulating chemosensitivity in HSCC. Here, we first employed ... ...

Abstract	PPARG has been reported to promote chemosensitivity in hypopharyngeal squamous cell carcinoma (HSCC). However, few studies tested its significance in the texture of a complex molecular network regulating chemosensitivity in HSCC. Here, we first employed RNA expression data analysis and literature data mining to uncover candidate genes related to HSCC chemosensitivity. Then, we constructed the molecular network regulating chemosensitivity in HSCC. After that, we employed degree centrality (DC) and weighted centrality (WC) to test the significance of PPARG within the regulating network. Pathway enrichment was done to study the cofunctions of PPARG and the rest of the genes within the network. The findings of our study contribute to the construction of a comprehensive network that regulates HSCC chemosensitivity, consisting of 57 genes, including PPARG. Notably, within this network, PPARG demonstrates a ranking of #5 and #13 based on DC and WC, respectively. Moreover, PPARG is connected to 29 out of the 57 genes and plays roles in multiple functional groups. These top related genes include AKT1, TP53, PTEN, MAPK1, NOTCH1, BECN1, PTGS2, SPP1, and RAC1. PPARG gets enriched in several key functional groups that have been implicated in the regulation of chemosensitivity, including those associated with the response to nutrients, vitamins, and peptides, the cellular response to chemical stress, and the regulation of hormone secretion and growth. Our results emphasize the involvement of PPARG and its interconnectedness with other genes in the regulation of HSCC chemosensitivity.
Language	English
Publishing date	2023-09-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	2237981-2
ISSN	1687-4765 ; 1687-4757
ISSN (online)	1687-4765
ISSN	1687-4757
DOI	10.1155/2023/6019318
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: An Approach to Interval-Valued Hesitant Fuzzy Multiattribute Group Decision Making Based on the Generalized Shapley-Choquet Integral

Lifei Zhang / Fanyong Meng

Complexity, Vol

2018 Volume 2018

Abstract: The purpose of this paper is to develop an approach to multiattribute group decision making under interval-valued hesitant fuzzy environment. To do this, this paper defines some new operations on interval-valued hesitant fuzzy elements, which eliminate ... ...

Abstract	The purpose of this paper is to develop an approach to multiattribute group decision making under interval-valued hesitant fuzzy environment. To do this, this paper defines some new operations on interval-valued hesitant fuzzy elements, which eliminate the disadvantages of the existing operations. Considering the fact that elements in a set may be interdependent, two generalized interval-valued hesitant fuzzy operators based on the generalized Shapley function and the Choquet integral are defined. Then, some models for calculating the optimal fuzzy measures on the expert set and the ordered position set are established. Because fuzzy measures are defined on the power set, it makes the problem exponentially complex. To simplify the complexity of solving a fuzzy measure, models for the optimal 2-additive measures are constructed. Finally, an investment problem is offered to show the practicality and efficiency of the new method.
Keywords	Electronic computers. Computer science ; QA75.5-76.95
Subject code	629
Language	English
Publishing date	2018-01-01T00:00:00Z
Publisher	Hindawi-Wiley
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: MiR-145 inhibited lipopolysaccharide-induced apoptosis of gastric mucosal via up-regulating JNK-mediated cytoprotective autophagy.

Meng, Fanyong / Chen, Jihua / Long, Qinglin / Liu, Dong

Pakistan journal of pharmaceutical sciences

2019 Volume 32, Issue 1(Supplementary), Page(s) 285–291

Abstract: It has been reported that specific microRNA could inhibit apoptosis of gastric mucosa. Our study was designed to investigate the effect and mechanisms of miR-145 in gastric mucosa. Gastric mucosal cells (GES-1) were treated with null-vector or miR-145 ... ...

Abstract	It has been reported that specific microRNA could inhibit apoptosis of gastric mucosa. Our study was designed to investigate the effect and mechanisms of miR-145 in gastric mucosa. Gastric mucosal cells (GES-1) were treated with null-vector or miR-145 over expression plasmid. Cell viability was determined by CCK-8 assay and detection of apoptosis by flow cytometry. Autophagic and apoptosis protein expression and c-Jun NH2-terminal kinase (JNK) phosphorylation were determined by Western blotting. Autophagy response and JNK activities were inhibited by specific inhibitor, 3MA or SP600125, respectively. LDH release assay was used to detect cytotoxicity. We confirmed that miR-145 triggered an autophagic response in GES-1 cells and depended on JNK activation. Blocking autophagy or JNK activation with specific inhibitor, 3MA or SP600125, potentiated cell death and caspase-3 activation. Furthermore, we confirmed that miR-145 enhanced the viability of GES-1 cells, phosphorylation of JNK and inhibited apoptosis of gastric mucosal miR-145 inhibited apoptosis of gastric mucosal via up-regulating JNK-mediated cytoprotective autophag.
MeSH term(s)	Anthracenes/pharmacology ; Apoptosis/drug effects ; Apoptosis/genetics ; Autophagy/drug effects ; Autophagy/genetics ; Cells, Cultured ; Gastric Mucosa/drug effects ; Gastric Mucosa/metabolism ; Gastric Mucosa/pathology ; Humans ; Lipopolysaccharides/pharmacology ; MAP Kinase Kinase 4/antagonists & inhibitors ; MAP Kinase Kinase 4/metabolism ; MicroRNAs/metabolism ; Protein Kinase Inhibitors/pharmacology ; Up-Regulation
Chemical Substances	Anthracenes ; Lipopolysaccharides ; MIRN145 microRNA, human ; MicroRNAs ; Protein Kinase Inhibitors ; pyrazolanthrone (1TW30Y2766) ; MAP Kinase Kinase 4 (EC 2.7.12.2)
Language	English
Publishing date	2019-03-04
Publishing country	Pakistan
Document type	Journal Article
ZDB-ID	885131-1
ISSN	1011-601X
ISSN	1011-601X
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A new approach for fair efficiency decomposition in two-stage structure system

An, Qingxian / Ang, Sheng / Chen, Xiaohong / Meng, Fanyong

Operational research : an international journal Vol. 18, No. 1 , p. 257-272

2018 Volume 18, Issue 1, Page(s) 257–272

Author's details	Qingxian An, Fanyong Meng, Sheng Ang, Xiaohong Chen
Keywords	Data envelopment analysis ; Efficiency decomposition ; Reference ratio ; Two-stage system
Language	English
Size	Online-Ressource
Publisher	Springer
Publishing place	Berlin
Document type	Article ; Online
ZDB-ID	2425760-6
ISSN	1866-1505 ; 1109-2858
ISSN (online)	1866-1505
ISSN	1109-2858
DOI	10.1007/s12351-016-0262-9
Database	ECONomics Information System

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Article ; Online: Preference Attitude-Based Method for Ranking Intuitionistic Fuzzy Numbers and Its Application in Renewable Energy Selection

Jian Lin / Fanyong Meng / Riqing Chen / Qiang Zhang

Complexity, Vol

2018 Volume 2018

Abstract: Many applications of intuitionistic fuzzy sets depend on ranking or comparing intuitionistic fuzzy numbers. This paper presents a novel ranking method for intuitionistic fuzzy numbers based on the preference attitudinal accuracy and score functions. The ... ...

Abstract	Many applications of intuitionistic fuzzy sets depend on ranking or comparing intuitionistic fuzzy numbers. This paper presents a novel ranking method for intuitionistic fuzzy numbers based on the preference attitudinal accuracy and score functions. The proposed ranking method considers not only the preference attitude of decision maker, but also all the possible values in feasible domain. Some desirable properties of preference attitudinal accuracy and score functions are verified in detail. A total order on the set of intuitionistic fuzzy numbers is established by using the proposed two functions. The proposed ranking method is also applied to select renewable energy. The advantage and validity of the proposed method are shown by comparing with some representative ranking methods.
Keywords	Electronic computers. Computer science ; QA75.5-76.95
Language	English
Publishing date	2018-01-01T00:00:00Z
Publisher	Hindawi-Wiley
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Scale evaluation and antiscalant testing based on fluorescent probe technology in RO process

Cheng, Zhiyang / Qin, Qingwen / Jia, Hui / Li, Juan / Yan, Fanyong / Meng, Xia / Wang, Jie

Journal of membrane science. 2021 Oct. 15, v. 636

2021

Abstract: Inventing the technology based on fluorescent probes to detect antiscalants in reverse osmosis (RO) concentrated water is of great significance for guiding the use of antiscalant and the control of scale. In this study, Amino trimethylene phosphonic acid ...

Abstract	Inventing the technology based on fluorescent probes to detect antiscalants in reverse osmosis (RO) concentrated water is of great significance for guiding the use of antiscalant and the control of scale. In this study, Amino trimethylene phosphonic acid (ATMP) was taken as the representative of the antiscalant, and a new fluorescent probe for ATMP detection was designed and synthesized. The new fluorescent probe showed high accuracy for ATMP detection (R² > 0.94) and resistance to the interference of ions (change rate <3%). Further, the use of probe to detect the antiscalant in RO concentrate and realize the evaluation of the scaling phenomenon was carried out. The model of the relationship between the probe fluorescence intensity and the concentration of precipitated ions was established to analyze the scale evaluation mechanism of the probe. Meanwhile, Critical fluorescence intensity (CFI) was introduced for scale evaluation. The results showed that the new probe could accurately judge the formation of scale under the condition of different antiscalant concentrations, and 926 ± 20 a.u. was judged as CFI for scaling evaluation. Finally, results of the new probe detection in RO scale evaluation test were consistent with the membrane flux and SEM detection, indicating that the probe can accurately evaluate scale during the RO operation. This research can provide technical support for the precise application of antiscalants and scale inhibition.
Keywords	fluorescence ; fluorescent dyes ; models ; phosphorous acid ; reverse osmosis
Language	English
Dates of publication	2021-1015
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	194516-6
ISSN	0376-7388
ISSN	0376-7388
DOI	10.1016/j.memsci.2021.119598
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Characterization of metallic-packaging fiber Bragg grating sensors with coated and bare fibers.

Zhang, Yumin / Meng, Fanyong / Song, Yanming / Dong, Mingli / Zhu, Lianqing

Applied optics

2019 Volume 58, Issue 6, Page(s) 1426–1432

Abstract: Metallic packaging of fiber Bragg grating (FBG) sensors is developed using the ultrasonic welding method. Both polyimide-coated fiber and bare fiber could be bonded well to aluminum alloy substrate using Sn-Bi alloy. Two kinds of metal-packaged FBG ... ...

Abstract	Metallic packaging of fiber Bragg grating (FBG) sensors is developed using the ultrasonic welding method. Both polyimide-coated fiber and bare fiber could be bonded well to aluminum alloy substrate using Sn-Bi alloy. Two kinds of metal-packaged FBG sensors, coated FBG and bare FBG, are characterized for studying the thermal sensitivity, strain response, short-term creep, and temporal temperature response. Both FBG sensors showed increasing sensitivity with temperature from -40°C to 80°C. The metal-packaged coated FBG sensor displayed relative strengths in strain stability, repeatability, creep, spectra shape, and temperature response when compared with the bare one. Moreover, the boundaries between optical fiber and metal alloy are intact, and cross-sectional scanning electron microscope micrographs clearly illustrated that metal alloy coated well with the coated and bare fiber.
Language	English
Publishing date	2019-03-15
Publishing country	United States
Document type	Journal Article
ISSN	1539-4522
ISSN (online)	1539-4522
DOI	10.1364/AO.58.001426
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Indoor Air Pollution by Methylsiloxane in Household and Automobile Settings.

Fanyong Meng / Hao Wu

PLoS ONE, Vol 10, Iss 8, p e

2015 Volume 0135509

Abstract: This study examines characteristics of atmospheric methylsiloxane pollution in indoor settings where interior renovation/redecoration is being undertaken, in addition to ordinary family homes and inside family cars. Concentrations of atmospheric ... ...

Abstract	This study examines characteristics of atmospheric methylsiloxane pollution in indoor settings where interior renovation/redecoration is being undertaken, in addition to ordinary family homes and inside family cars. Concentrations of atmospheric methylsiloxane in these locations were approximately one order of magnitude higher than that in outdoor areas. The average indoor concentration of methylsiloxane where renovation was being undertaken was 9.4 μg/m3, which is slightly higher than that in an ordinary family home (7.88 μg/m3), while samples from family cars showed lower concentration (3.10 μg/m3). The indoor atmospheric concentration during renovation/redecoration work was significantly positively correlated with the duration of the work. The structure of atmospheric methylsiloxane pollution is basically the same in these three venues. The concentration of annulus siloxane was much higher than that of linear compounds (85% of the total methylsiloxane concentrations). Household dust in average family homes showed total methylsiloxane concentration of 9.5 μg/m3 (average); the structure mainly consisted of linear siloxane (approximately 98% of total concentration), thereby differing from that of atmospheric methylsiloxane pollution. The comparatively high concentration of methylsiloxane in these three venues indicates that interior renovation and decoration work, and even travelling in cars, can involve exposure to more serious siloxane contamination during everyday activities.
Keywords	Medicine ; R ; Science ; Q
Subject code	333
Language	English
Publishing date	2015-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Fiber grating sensing interrogation system based on a modulated grating Y-branch tunable laser for core-and-cladding-integrated fiber Bragg grating temperature measurement.

Liu, Jia / Zhu, Lianqing / He, Wei / Wang, Yongqian / Meng, Fanyong / Song, Yanming

The Review of scientific instruments

2020 Volume 91, Issue 1, Page(s) 14904

Abstract: Numerous studies have addressed various methods to interrogate fiber Bragg gratings (FBGs). However, conventional methods are ineffective for multipeak FBG demodulation. A core-and-cladding-integrated fiber Bragg grating (FBG) temperature-interrogation ... ...

Abstract	Numerous studies have addressed various methods to interrogate fiber Bragg gratings (FBGs). However, conventional methods are ineffective for multipeak FBG demodulation. A core-and-cladding-integrated fiber Bragg grating (FBG) temperature-interrogation system, based on a modulated grating Y-branch (MG-Y) tunable laser and home-built FBG, is proposed in this study. The sensing system comprises an MG-Y tunable laser interrogation system, a 3-dB optical fiber coupler, a core-and-cladding-integrated FBG, a heating platform, and a personal computer. The core-and-cladding-integrated FBG with two reflection peaks is sampled by the designed MG-Y laser. The FBG has a period of 534 nm and a grating length of 2000 µm. It is fabricated in a single-mode fiber by femtosecond-laser writing through the fiber coating. The interrogator is suitable for temperature measurement via the core-and-cladding-integrated FBG. In tests of the temperature-interrogation system, a temperature change from 30 to 100 °C generates spectral shifts toward longer wavelengths for both the core and cladding reflection peaks. For the core and cladding, temperature sensing sensitivities of 111 and 113 pm/°C with linearities of 0.993 and 0.99, respectively, during heating and 117 and 120 pm/°C with linearity coefficients of 0.994 and 0.99, respectively, during cooling are achieved.
Language	English
Publishing date	2020-02-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	209865-9
ISSN	1089-7623 ; 0034-6748
ISSN (online)	1089-7623
ISSN	0034-6748
DOI	10.1063/1.5132919
Database	MEDical Literature Analysis and Retrieval System OnLINE

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