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  1. Article ; Online: Knowledge, attitudes and acceptance toward Human papillomavirus (HPV) vaccination: Perspectives of Muslim women and men

    Al Alawi, Salma / Al Zaabi, Omar / Heffernan, Margaret E. / Arulappan, Judie / Al Hasani, Noora / Al Baluchi, Munira / Al Mamari, Alia / Al Saadi, Amani

    Vaccine. 2023 Feb. 28,

    2023  

    Abstract: Human papillomavirus (HPV) infection is the leading risk factor for the development of anogenital cancers. Most Arab countries lack both HPV education and national HPV vaccination programs. The objective of this study was to assess knowledge, attitudes, ... ...

    Abstract Human papillomavirus (HPV) infection is the leading risk factor for the development of anogenital cancers. Most Arab countries lack both HPV education and national HPV vaccination programs. The objective of this study was to assess knowledge, attitudes, and acceptance toward HPV vaccination in men and women from Oman, a country in the Middle Eastern North Africa region. This cross-sectional quantitative study used convenience sampling to recruit male and female participants, aged 18 years and above from all 11 governorates of Oman to complete a validated self-administered questionnaire online in the Arabic language. The questionnaire comprised five sections, with a total of 32 questions. The questionnaire, including Arabic and English versions, was content validated and piloted. A total of 1403 participants, including 952 parents and 369 healthcare providers, completed the survey. The results showed a lack of knowledge regarding HPV infection and vaccines, including among healthcare providers. Less than a quarter of the participants had heard of HPV infection, with digital sources of information being the most common. Factors such as being a woman or a healthcare provider or completing higher levels of education were independently and significantly positively association with HPV awareness (p < 0.001). The majority of the participants lacked vaccine safety knowledge, had concerns about the vaccine's side effects, and sought reassurance of its protection against HPV infection (62%, 71.5%, and 84.6%, respectively). Nevertheless, nearly two-thirds of the participants agreed to take the HPV vaccine, with support for both boys and girls being vaccinated. There was almost universal agreement among the participants regarding the need for parental and adolescent HPV educational programs. Omani women and men showed a high level of acceptance and favorable attitude toward HPV vaccination. The study findings support future efforts to implement school and public-level HPV education and a national HPV vaccination program in Oman.
    Keywords Muslims ; Papillomaviridae ; adolescents ; education ; females ; health care workers ; health services ; humans ; males ; questionnaires ; risk factors ; surveys ; vaccination ; vaccines ; women ; Northern Africa ; Oman ; Cervical cancer ; Human papillomavirus ; HPV vaccine ; HPV knowledge ; Attitudes ; Muslim
    Language English
    Dates of publication 2023-0228
    Publishing place Elsevier Ltd
    Document type Article ; Online
    Note Pre-press version
    ZDB-ID 605674-x
    ISSN 1873-2518 ; 0264-410X
    ISSN (online) 1873-2518
    ISSN 0264-410X
    DOI 10.1016/j.vaccine.2023.02.063
    Database NAL-Catalogue (AGRICOLA)

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  2. Article: Familial occurrence of pulmonary alveolar microlithiasis in 3 siblings.

    Al-Alawi, Alia S

    Saudi medical journal

    2006  Volume 27, Issue 2, Page(s) 238–240

    Abstract: Pulmonary alveolar microlithiasis (PAM) is a rare disease of unknown etiology characterized by intra-alveolar calcium deposits. More than 500 cases were reported in the literature. The disorder affects people at every age beginning from the early ... ...

    Abstract Pulmonary alveolar microlithiasis (PAM) is a rare disease of unknown etiology characterized by intra-alveolar calcium deposits. More than 500 cases were reported in the literature. The disorder affects people at every age beginning from the early childhood. It occurs probably as a result of autosomal recessive transmission. Familial occurrence is often found with family history of the disease being present in up to 50% of the reported cases. We report PAM in 3 siblings.
    MeSH term(s) Adult ; Humans ; Lithiasis/genetics ; Lung Diseases/genetics ; Male ; Pulmonary Alveoli
    Language English
    Publishing date 2006-02
    Publishing country Saudi Arabia
    Document type Case Reports ; Journal Article
    ZDB-ID 392302-2
    ISSN 1658-3175 ; 0379-5284
    ISSN (online) 1658-3175
    ISSN 0379-5284
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Knowledge, attitudes and acceptance toward Human papillomavirus (HPV) vaccination: Perspectives of Muslim women and men.

    Al Alawi, Salma / Al Zaabi, Omar / Heffernan, Margaret E / Arulappan, Judie / Al Hasani, Noora / Al Baluchi, Munira / Al Mamari, Alia / Al Saadi, Amani

    Vaccine

    2023  Volume 41, Issue 13, Page(s) 2224–2233

    Abstract: Objectives: Human papillomavirus (HPV) infection is the leading risk factor for the development of anogenital cancers. Most Arab countries lack both HPV education and national HPV vaccination programs. The objective of this study was to assess knowledge, ...

    Abstract Objectives: Human papillomavirus (HPV) infection is the leading risk factor for the development of anogenital cancers. Most Arab countries lack both HPV education and national HPV vaccination programs. The objective of this study was to assess knowledge, attitudes, and acceptance toward HPV vaccination in men and women from Oman, a country in the Middle Eastern North Africa region.
    Methods: This cross-sectional quantitative study used convenience sampling to recruit male and female participants, aged 18 years and above from all 11 governorates of Oman to complete a validated self-administered questionnaire online in the Arabic language. The questionnaire comprised five sections, with a total of 32 questions. The questionnaire, including Arabic and English versions, was content validated and piloted.
    Results: A total of 1403 participants, including 952 parents and 369 healthcare providers, completed the survey. The results showed a lack of knowledge regarding HPV infection and vaccines, including among healthcare providers. Less than a quarter of the participants had heard of HPV infection, with digital sources of information being the most common. Factors such as being a woman or a healthcare provider or completing higher levels of education were independently and significantly positively association with HPV awareness (p < 0.001). The majority of the participants lacked vaccine safety knowledge, had concerns about the vaccine's side effects, and sought reassurance of its protection against HPV infection (62%, 71.5%, and 84.6%, respectively). Nevertheless, nearly two-thirds of the participants agreed to take the HPV vaccine, with support for both boys and girls being vaccinated. There was almost universal agreement among the participants regarding the need for parental and adolescent HPV educational programs.
    Conclusion: Omani women and men showed a high level of acceptance and favorable attitude toward HPV vaccination. The study findings support future efforts to implement school and public-level HPV education and a national HPV vaccination program in Oman.
    MeSH term(s) Adolescent ; Humans ; Male ; Female ; Papillomavirus Infections/prevention & control ; Human Papillomavirus Viruses ; Health Knowledge, Attitudes, Practice ; Cross-Sectional Studies ; Islam ; Vaccination ; Surveys and Questionnaires ; Uterine Cervical Neoplasms/prevention & control ; Papillomavirus Vaccines ; Patient Acceptance of Health Care
    Chemical Substances Papillomavirus Vaccines
    Language English
    Publishing date 2023-02-28
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 605674-x
    ISSN 1873-2518 ; 0264-410X
    ISSN (online) 1873-2518
    ISSN 0264-410X
    DOI 10.1016/j.vaccine.2023.02.063
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Study of Leptin and Adiponectin as Disease Markers in Subjects with Obstructive Sleep Apnea

    Sana Al Mutairi / Olusegun A. Mojiminiyi / Alia Al Alawi / Tahani Al Rammah / Nabila Abdella

    Disease Markers, Vol

    2014  Volume 2014

    Keywords Medicine (General) ; R5-920 ; Medicine ; R
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Hindawi Publishing Corporation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Prevalence, risk factors and impact on daytime sleepiness and hypertension of periodic leg movements with arousals in patients with obstructive sleep apnea.

    Al-Alawi, Alia / Mulgrew, Alan / Tench, Elizabeth / Ryan, C Frank

    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

    2006  Volume 2, Issue 3, Page(s) 281–287

    Abstract: Study objective: To determine the prevalence, risk factors, and impact on daytime sleepiness and hypertension of periodic leg movements of sleep (PLMS) with associated arousals in patients with obstructive sleep apnea (OSA).: Methods: A single-center ...

    Abstract Study objective: To determine the prevalence, risk factors, and impact on daytime sleepiness and hypertension of periodic leg movements of sleep (PLMS) with associated arousals in patients with obstructive sleep apnea (OSA).
    Methods: A single-center retrospective case series of 798 consecutive patients who underwent diagnostic overnight polysomnography for suspected OSA. We performed discriminant function analysis using clinical and polysomnographic variables to examine the relationship between PLMS (periodic leg movement arousal index > or =5 per hour) and potential risk factors, including OSA.
    Results: Mean +/- SD age was 50 +/- 12 years, body mass index 32 +/- 8 kg/m2, Epworth Sleepiness Scale (ESS) score 11 +/- 5, and apnea-hypopnea index 31 +/- 26 per hour. Sixty-eight percent were men, 30% had systemic hypertension, and 19% were smokers. Ninety-two percent had OSA (apnea-hypopnea index +/- 5); 47% had PLMS; 44% had both OSA and PLMS; and among patients with OSA, 48% had PLMS. Significant predictors of PLMS, in order of importance, were number of predisposing medical conditions, age, number of predisposing medications, obesity, and OSA. Medical conditions that significantly predicted PLMS were depression, fibromyalgia, and diabetes mellitus. The ESS score and hypertension status were no different between those with both OSA and PLMS and those with OSA alone.
    Conclusions: One in 2 patients investigated for OSA has PLMS. Risk factors for PLMS include preexisting medical conditions-particularly depression, fibromyalgia, and diabetes mellitus-increasing age, predisposing medications, obesity, and OSA. The combination of OSA and PLMS results in no greater subjective daytime sleepiness or prevalence of hypertension than OSA alone.
    MeSH term(s) Arousal/physiology ; Body Mass Index ; Disorders of Excessive Somnolence/epidemiology ; Female ; Humans ; Hypertension/epidemiology ; Male ; Middle Aged ; Nocturnal Myoclonus Syndrome/epidemiology ; Polysomnography ; Prevalence ; Risk Factors ; Sleep Apnea, Obstructive/epidemiology ; Sleep Disorders, Circadian Rhythm/epidemiology
    Language English
    Publishing date 2006-07-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2397213-0
    ISSN 1550-9389
    ISSN 1550-9389
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Study of leptin and adiponectin as disease markers in subjects with obstructive sleep apnea.

    Al Mutairi, Sana / Mojiminiyi, Olusegun A / Al Alawi, Alia / Al Rammah, Tahani / Abdella, Nabila

    Disease markers

    2014  Volume 2014, Page(s) 706314

    Abstract: Background: Published studies showed conflicting results of the associations between adiponectin and leptin levels and obstructive sleep apnoea (OSA). In obese patients, plasma leptin is elevated and adiponectin is decreased, and we postulate that these ...

    Abstract Background: Published studies showed conflicting results of the associations between adiponectin and leptin levels and obstructive sleep apnoea (OSA). In obese patients, plasma leptin is elevated and adiponectin is decreased, and we postulate that these adipokines could be potential markers of clinical and metabolic perturbations in patients with OSA.
    Methods: 147 patients with suspected OSA had polysomnography to determine the Respiratory Disturbance Index (RDI). We measured fasting plasma glucose (FPG), fasting serum insulin, plasma leptin, adiponectin, and full lipid profile. Patients were classified on the basis of the RDI, degree of adiposity, and insulin resistance (IR) (homeostasis model assessment of insulin resistance (HOMAIR)).
    Results: 28.6% of subjects had normal polysomnography, 34.8% had mild OSA, 19.6% had moderate OSA, and 17% had severe OSA. Obesity was more prevalent in subjects with moderate-severe OSA (47%). Adiponectin decreased significantly (P = 0.041) with increasing severity of OSA. Though BMI was significantly higher in subjects with severe OSA, paradoxically, leptin was lowest in those subjects independent of gender dimorphism.
    Conclusions: Adiponectin is an independent marker of disease severity in patients with OSA. The paradoxical decrease in circulating leptin, which suggests impaired secretion, deserves further studies as a potential marker of severe OSA.
    MeSH term(s) Adiponectin/blood ; Adult ; Aged ; Biomarkers/blood ; Female ; Humans ; Leptin/blood ; Male ; Middle Aged ; Neck/pathology ; Severity of Illness Index ; Sex Characteristics ; Sleep Apnea, Obstructive/blood ; Sleep Apnea, Obstructive/pathology
    Chemical Substances ADIPOQ protein, human ; Adiponectin ; Biomarkers ; Leptin
    Language English
    Publishing date 2014-05-29
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 604951-5
    ISSN 1875-8630 ; 0278-0240
    ISSN (online) 1875-8630
    ISSN 0278-0240
    DOI 10.1155/2014/706314
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Study of Leptin and Adiponectin as Disease Markers in Subjects with Obstructive Sleep Apnea

    Sana Al Mutairi / Olusegun A. Mojiminiyi / Alia Al Alawi / Tahani Al Rammah / Nabila Abdella

    Disease Markers, Vol

    2014  Volume 2014

    Abstract: Background. Published studies showed conflicting results of the associations between adiponectin and leptin levels and obstructive sleep apnoea (OSA). In obese patients, plasma leptin is elevated and adiponectin is decreased, and we postulate that these ... ...

    Abstract Background. Published studies showed conflicting results of the associations between adiponectin and leptin levels and obstructive sleep apnoea (OSA). In obese patients, plasma leptin is elevated and adiponectin is decreased, and we postulate that these adipokines could be potential markers of clinical and metabolic perturbations in patients with OSA. Methods. 147 patients with suspected OSA had polysomnography to determine the Respiratory Disturbance Index (RDI). We measured fasting plasma glucose (FPG), fasting serum insulin, plasma leptin, adiponectin, and full lipid profile. Patients were classified on the basis of the RDI, degree of adiposity, and insulin resistance (IR) (homeostasis model assessment of insulin resistance (HOMAIR)). Results. 28.6% of subjects had normal polysomnography, 34.8% had mild OSA, 19.6% had moderate OSA, and 17% had severe OSA. Obesity was more prevalent in subjects with moderate-severe OSA (47%). Adiponectin decreased significantly (P=0.041) with increasing severity of OSA. Though BMI was significantly higher in subjects with severe OSA, paradoxically, leptin was lowest in those subjects independent of gender dimorphism. Conclusions. Adiponectin is an independent marker of disease severity in patients with OSA. The paradoxical decrease in circulating leptin, which suggests impaired secretion, deserves further studies as a potential marker of severe OSA.
    Keywords Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Aspergillus-related lung disease.

    Al-Alawi, Alia / Ryan, C Frank / Flint, Julia D / Müller, Nestor L

    Canadian respiratory journal

    2005  Volume 12, Issue 7, Page(s) 377–387

    Abstract: Aspergillus is a ubiquitous dimorphic fungus that causes a variety of human diseases ranging in severity from trivial to life-threatening, depending on the host response. An intact host defence is important to prevent disease, but individuals with pre- ... ...

    Abstract Aspergillus is a ubiquitous dimorphic fungus that causes a variety of human diseases ranging in severity from trivial to life-threatening, depending on the host response. An intact host defence is important to prevent disease, but individuals with pre-existing structural lung disease, atopy, occupational exposure or impaired immunity are susceptible. Three distinctive patterns of aspergillus-related lung disease are recognized: saprophytic infestation of airways, cavities and necrotic tissue; allergic disease including extrinsic allergic alveolitis, asthma, allergic bronchopulmonary aspergillosis, bronchocentric granulomatosis and chronic eosinophilic pneumonia; and airway and tissue invasive disease -- pseudomembranous tracheobronchitis, acute bronchopneumonia, angioinvasive aspergillosis, chronic necrotizing aspergillosis and invasive pleural disease. A broad knowledge of these clinical presentations and a high index of suspicion are required to ensure timely diagnosis and treatment of the potentially lethal manifestations of aspergillus-related pulmonary disease. In the present report, the clinical, radiographic and pathological aspects of the various aspergillus-related lung diseases are briefly reviewed.
    MeSH term(s) Aspergillosis/diagnosis ; Aspergillosis/pathology ; Aspergillosis, Allergic Bronchopulmonary/diagnosis ; Aspergillosis, Allergic Bronchopulmonary/pathology ; Humans ; Lung Diseases, Fungal/diagnosis ; Lung Diseases, Fungal/pathology
    Language English
    Publishing date 2005-10
    Publishing country Egypt
    Document type Journal Article ; Review
    ZDB-ID 1213103-9
    ISSN 1916-7245 ; 1198-2241
    ISSN (online) 1916-7245
    ISSN 1198-2241
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Demographic pattern and clinical characteristics of patients with smear- positive pulmonary tuberculosis in kuwait.

    Abal, Adnan T / Jayakrishnan, B / Parwer, Shahid / El Shamy, Abdul Salam / Khadadah, Mousa / Ayed, Adel / Al Alawi, Alia

    Medical principles and practice : international journal of the Kuwait University, Health Science Centre

    2005  Volume 14, Issue 5, Page(s) 306–312

    Abstract: Objective: The aim of this study was to document various clinical factors that are likely to be of help in the control of tuberculosis in Kuwait.: Subjects and methods: Details of patients with sputum positive for acid-fast bacilli in the period from ...

    Abstract Objective: The aim of this study was to document various clinical factors that are likely to be of help in the control of tuberculosis in Kuwait.
    Subjects and methods: Details of patients with sputum positive for acid-fast bacilli in the period from January 1998 to December 2000 were collected retrospectively from the case records and population statistics from government sources. The data were then tabulated and analyzed.
    Results: Of the 526 cases, 83.5% were expatriates and 16.5% Kuwaiti; 373 (70.9%) were male. Of the expatriates, 66.7% were from Asia and the Far East, 5.7% were > or =60 years. The annual incidence was 8.34 per 100,000 population. The lowest incidence was observed in the Jahrah governorate with an overall incidence of 5 (2.0 among Kuwaitis and 6.4 among expatriates) per 100,000 population. The highest incidence overall (10.2) and among Kuwaitis (4.1) was observed in the Farwaniya governorate, while the highest incidence among expatriates was seen in the Capital governorate (13.4). Radiologically, 94 (19.5%) had minimal, 246 (51.5%) had moderately advanced and 141 (29.3%) far-advanced disease. The majority of the patients (72%) had only + status for AFB in the smear. Hypercalcemia (25.7%), hyponatremia (22.15%) and hyperglycemia (29.9%) were common in the patients. Mean serum albumin was low (28.7 +/- 5.5 g/l). Two hundred and forty-seven (47.2%) were declared cured while 116 (22.2%) completed treatment. Comparison between nationals and expatriates showed a significant difference only for age, smoking status, defaulter rate and place of residence.
    Conclusion: The lowest regional incidence was found in the Jahrah governorate. Both biochemical abnormalities and radiologically advanced presentations were common. Disease pattern and response to treatment was purely individual and did not differ with respect to nationality or race.
    MeSH term(s) Adult ; Aged ; Demography ; Emigration and Immigration ; Female ; Humans ; Hypercalcemia/epidemiology ; Hyperglycemia/epidemiology ; Hyponatremia/epidemiology ; Incidence ; Kuwait/epidemiology ; Male ; Middle Aged ; Registries ; Severity of Illness Index ; Sputum/microbiology ; Treatment Outcome ; Tuberculosis, Pulmonary/complications ; Tuberculosis, Pulmonary/diagnosis ; Tuberculosis, Pulmonary/epidemiology
    Language English
    Publishing date 2005-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 645108-1
    ISSN 1423-0151 ; 1011-7571
    ISSN (online) 1423-0151
    ISSN 1011-7571
    DOI 10.1159/000086927
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Demographic Pattern and Clinical Characteristics of Patients with Smear- Positive Pulmonary Tuberculosis in Kuwait

    Abal, Adnan T. / Jayakrishnan, B. / Parwer, Shahid / El Shamy, Abdul Salam / Khadadah, Mousa / Ayed, Adel / Al Alawi, Alia

    Medical Principles and Practice

    2005  Volume 14, Issue 5, Page(s) 306–312

    Abstract: Objective: The aim of this study was to document various clinical factors that are likely to be of help in the control of tuberculosis in Kuwait. Subjects and Methods: Details of patients with sputum positive for acid-fast bacilli in the period from ... ...

    Institution Departments of Medicine and Surgery, Kuwait University Chest Unit, Al Rasheed Allergy Center, and Chest Unit, Al-Amiri Hospital, Safat, Kuwait
    Abstract Objective: The aim of this study was to document various clinical factors that are likely to be of help in the control of tuberculosis in Kuwait. Subjects and Methods: Details of patients with sputum positive for acid-fast bacilli in the period from January 1998 to December 2000 were collected retrospectively from the case records and population statistics from government sources. The data were then tabulated and analyzed. Results: Of the 526 cases, 83.5% were expatriates and 16.5% Kuwaiti; 373 (70.9%) were male. Of the expatriates, 66.7% were from Asia and the Far East, 5.7% were ≧60 years. The annual incidence was 8.34 per 100,000 population. The lowest incidence was observed in the Jahrah governorate with an overall incidence of 5 (2.0 among Kuwaitis and 6.4 among expatriates) per 100,000 population. The highest incidence overall (10.2) and among Kuwaitis (4.1) was observed in the Farwaniya governorate, while the highest incidence among expatriates was seen in the Capital governorate (13.4). Radiologically, 94 (19.5%) had minimal, 246 (51.5%) had moderately advanced and 141 (29.3%) far-advanced disease. The majority of the patients (72%) had only + status for AFB in the smear. Hypercalcemia (25.7%), hyponatremia (22.15%) and hyperglycemia (29.9%) were common in the patients. Mean serum albumin was low (28.7 ± 5.5 g/l). Two hundred and forty-seven (47.2%) were declared cured while 116 (22.2%) completed treatment. Comparison between nationals and expatriates showed a significant difference only for age, smoking status, defaulter rate and place of residence. Conclusion: The lowest regional incidence was found in the Jahrah governorate. Both biochemical abnormalities and radiologically advanced presentations were common. Disease pattern and response to treatment was purely individual and did not differ with respect to nationality or race.
    Keywords Hypercalcemia ; Tuberculosis epidemiology ; Sputum smear
    Language English
    Publishing date 2005-08-18
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    Note Original Paper
    ZDB-ID 645108-1
    ISSN 1423-0151 ; 1011-7571
    ISSN (online) 1423-0151
    ISSN 1011-7571
    DOI 10.1159/000086927
    Database Karger publisher's database

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