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  1. Article ; Online: Bibliometric Analysis of Brain Stimulation Technologies in Sleep Disorders.

    Shen, Chao / Wang, Zhao-Di / Qian, Wen-Jun / Wu, Cheng-Fan / Qian, Su-Rong / Tang, Tong

    Medical science monitor : international medical journal of experimental and clinical research

    2024  Volume 30, Page(s) e942687

    Abstract: BACKGROUND Sleep disorders are a common disease faced by people today and can lead to fatigue, lack of concentration, impaired memory, and even death. In recent years, the development of brain stimulation techniques has provided a new perspective for the ...

    Abstract BACKGROUND Sleep disorders are a common disease faced by people today and can lead to fatigue, lack of concentration, impaired memory, and even death. In recent years, the development of brain stimulation techniques has provided a new perspective for the treatment of sleep disorders. However, there is a lack of bibliometric analyses related to sleep disorders and brain stimulation techniques. Therefore, this study analyzed the application status and trend of brain stimulation technology in sleep disorder research. MATERIAL AND METHODS Articles and reviews published between 1999 and 2023 were retrieved from the Web of Science. CiteSpace was used to visually analyze the publications, countries, institutions, journals, authors, references, and keywords. RESULTS A total of 459 publications were obtained. The number of studies was shown to be on a general upward trend. The country with the largest number of publications was the United States; UDICE-French Research Universities had the highest number of publications; Neurology had the highest citation frequency; 90% of the top 10 references cited were from Journal Citation Reports Q1; Brigo was the author with the highest number of publications; and the most frequent keywords were "transcranial magnetic stimulation", "deep brain stimulation", and "Parkinson disease". CONCLUSIONS Our study used CiteSpace software to analyze 459 studies published since 1999 on brain stimulation techniques for the treatment of sleep disorders, revealing research trends and the current state of the field. Our results will help researchers to understand the existing research quickly and provide direction for future research.
    MeSH term(s) Humans ; Bibliometrics ; Fatigue ; Sleep Wake Disorders/therapy ; Technology ; Brain
    Language English
    Publishing date 2024-03-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1439041-3
    ISSN 1643-3750 ; 1234-1010
    ISSN (online) 1643-3750
    ISSN 1234-1010
    DOI 10.12659/MSM.942687
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Circ_MACF1 targets miR-421 to upregulate FMO2 to suppress paclitaxel resistance and malignant cellular behaviors in lung adenocarcinoma.

    Qian, Xiaoting / Chen, Chunhua / Tong, Sanxiang / Zhang, Jun

    Thoracic cancer

    2023  Volume 14, Issue 33, Page(s) 3348–3357

    Abstract: Background: Chemoresistance remains an enormous challenge in the treatment of lung adenocarcinoma (LADC). Circular RNAs (circRNAs) exhibit important regulation in tumor progression and chemoresistance. This research focused on exploring the regulatory ... ...

    Abstract Background: Chemoresistance remains an enormous challenge in the treatment of lung adenocarcinoma (LADC). Circular RNAs (circRNAs) exhibit important regulation in tumor progression and chemoresistance. This research focused on exploring the regulatory function and mechanism of circ_MACF1 (has_circ_0011780) in paclitaxel (PTX) resistance in LADC.
    Methods: Circ_MACF1, miR-421 and flavin-containing monooxygenase 2 (FMO2) were determined by RT-qPCR. MTT was applied to detect IC
    Results: Expression of circ_MACF1 was decreased in PTX-resistant LADC tissues and cells. Circ_MACF1 overexpression reduced chemoresistance, proliferation, motility and accelerated apoptosis in PTX-resistant LADC cells. Circ_MACF1 targeted miR-421 and miR-421 upregulation reverted circ_MACF1-evoked effects. FMO2 served as a downstream target of miR-421 and circ_MACF1 sponged miR-421 to elevate the expression of FMO2. MiR-421 enhanced PTX resistance and LADC progression via targeting FMO2. FMO2 knockdown enhanced IC
    Conclusion: These findings elucidated that circ_MACF1 inhibited PTX resistance by absorbing miR-421 to upregulate FMO2 in LADC.
    MeSH term(s) Humans ; Adenocarcinoma of Lung/drug therapy ; Adenocarcinoma of Lung/genetics ; Cytoskeletal Proteins ; Cell Proliferation ; Lung Neoplasms/drug therapy ; Lung Neoplasms/genetics ; MicroRNAs/genetics ; Cell Line, Tumor ; Microfilament Proteins
    Chemical Substances dimethylaniline monooxygenase (N-oxide forming) (EC 1.14.13.8) ; Cytoskeletal Proteins ; MicroRNAs ; MACF1 protein, human ; Microfilament Proteins ; MIRN421 microRNA, human
    Language English
    Publishing date 2023-10-10
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2625856-0
    ISSN 1759-7714 ; 1759-7706
    ISSN (online) 1759-7714
    ISSN 1759-7706
    DOI 10.1111/1759-7714.15132
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Psoralen and Isopsoralen,

    Chen, Liang-Min / Qian, Si-Tong / Li, Zhuo-Qing / He, Ming-Fang / Li, Hui-Jun

    Chemical research in toxicology

    2024  

    Abstract: With the increasing use of oral contraceptives and estrogen replacement therapy, the incidence of estrogen-induced cholestasis (EC) has tended to rise. Psoralen (P) and isopsoralen (IP) are the major bioactive components in Psoraleae Fructus, and their ... ...

    Abstract With the increasing use of oral contraceptives and estrogen replacement therapy, the incidence of estrogen-induced cholestasis (EC) has tended to rise. Psoralen (P) and isopsoralen (IP) are the major bioactive components in Psoraleae Fructus, and their estrogen-like activities have already been recognized. Recent studies have also reported that ERK1/2 plays a critical role in EC in mice. This study aimed to investigate whether P and IP induce EC and reveal specific mechanisms. It was found that P and IP increased the expression of
    Language English
    Publishing date 2024-04-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639353-6
    ISSN 1520-5010 ; 0893-228X
    ISSN (online) 1520-5010
    ISSN 0893-228X
    DOI 10.1021/acs.chemrestox.4c00054
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Tailoring the Coordination Environment of Fe/Zn-BDC to Boost Peroxidase-like Activity for Highly Selective Detection of PFOS.

    Liu, Qian / Chen, Qiumeng / Tong, Yuan-Jun / Zou, Xue / Zheng, Xiaoke / Gong, Zhengjun

    Analytical chemistry

    2024  Volume 96, Issue 11, Page(s) 4673–4681

    Abstract: Perfluorooctanesulfonic acid potassium salt (PFOS) residues in ecosystems over long periods are of increasing concern and require a selective and stable optical probe for monitoring. Herein, two functional groups (-F and - ... ...

    Abstract Perfluorooctanesulfonic acid potassium salt (PFOS) residues in ecosystems over long periods are of increasing concern and require a selective and stable optical probe for monitoring. Herein, two functional groups (-F and -NH
    MeSH term(s) Potassium ; Ecosystem ; Colorimetry ; Peroxidases ; Zinc
    Chemical Substances Potassium (RWP5GA015D) ; Peroxidases (EC 1.11.1.-) ; Zinc (J41CSQ7QDS)
    Language English
    Publishing date 2024-03-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.4c00016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Exceptional structural phase transition near room temperature in an organic-inorganic hybrid ferroelectric.

    Wang, Ping / Tong, Yu-Qiao / Yin, Shi-Qing / Gu, Qian-Jun / Huang, Bo / Zhu, Ai-Xin

    Chemical communications (Cambridge, England)

    2023  Volume 59, Issue 91, Page(s) 13651–13654

    Abstract: An organic-inorganic hybrid ferroelectric, ( ... ...

    Abstract An organic-inorganic hybrid ferroelectric, (C
    Language English
    Publishing date 2023-11-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/d3cc04186g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Thiol redox proteomics: Characterization of thiol-based post-translational modifications.

    Li, Xiaolu / Gluth, Austin / Zhang, Tong / Qian, Wei-Jun

    Proteomics

    2023  Volume 23, Issue 13-14, Page(s) e2200194

    Abstract: Redox post-translational modifications on cysteine thiols (redox PTMs) have profound effects on protein structure and function, thus enabling regulation of various biological processes. Redox proteomics approaches aim to characterize the landscape of ... ...

    Abstract Redox post-translational modifications on cysteine thiols (redox PTMs) have profound effects on protein structure and function, thus enabling regulation of various biological processes. Redox proteomics approaches aim to characterize the landscape of redox PTMs at the systems level. These approaches facilitate studies of condition-specific, dynamic processes implicating redox PTMs and have furthered our understanding of redox signaling and regulation. Mass spectrometry (MS) is a powerful tool for such analyses which has been demonstrated by significant advances in redox proteomics during the last decade. A group of well-established approaches involves the initial blocking of free thiols followed by selective reduction of oxidized PTMs and subsequent enrichment for downstream detection. Alternatively, novel chemoselective probe-based approaches have been developed for various redox PTMs. Direct detection of redox PTMs without any enrichment has also been demonstrated given the sensitivity of contemporary MS instruments. This review discusses the general principles behind different analytical strategies and covers recent advances in redox proteomics. Several applications of redox proteomics are also highlighted to illustrate how large-scale redox proteomics data can lead to novel biological insights.
    MeSH term(s) Sulfhydryl Compounds/chemistry ; Proteomics/methods ; Protein Processing, Post-Translational ; Proteins/metabolism ; Oxidation-Reduction ; Proteome/metabolism
    Chemical Substances Sulfhydryl Compounds ; Proteins ; Proteome
    Language English
    Publishing date 2023-05-29
    Publishing country Germany
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 2032093-0
    ISSN 1615-9861 ; 1615-9853
    ISSN (online) 1615-9861
    ISSN 1615-9853
    DOI 10.1002/pmic.202200194
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Phytoplankton dynamics and implications for eutrophication management in an urban river with a series of rubber dams.

    Bao, Linlin / Chen, Jie / Tong, Hongjin / Qian, Jun / Li, Xuyong

    Journal of environmental management

    2022  Volume 311, Page(s) 114865

    Abstract: Rubber dams are widely used in urban rivers for landscape construction and flood control. However, the increased water residence time by dams usually causes phytoplankton accumulation. Developing a greater understanding of the phytoplankton dynamics and ... ...

    Abstract Rubber dams are widely used in urban rivers for landscape construction and flood control. However, the increased water residence time by dams usually causes phytoplankton accumulation. Developing a greater understanding of the phytoplankton dynamics and the effecting factors is essential for the eutrophication control of dammed rivers. Here, we investigated the variations in biomass and structure of phytoplankton communities along an urban landscape river with 30 rubber dams, and the main controlling factors during a 2-yr field monitoring. The biomass of phytoplankton significantly increased from 12.7 μg/L-Chl a and 1.14 × 10
    Language English
    Publishing date 2022-03-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 184882-3
    ISSN 1095-8630 ; 0301-4797
    ISSN (online) 1095-8630
    ISSN 0301-4797
    DOI 10.1016/j.jenvman.2022.114865
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Interfacial Modulation of Spin-Orbit Torques Induced by Two-Dimensional van der Waals Material ZrSe

    Cao, Lulu / Chen, Qian / Zhu, Yonghui / Tong, Kaiyu / Li, Wenjia / Ma, Jun / Jalali, Milad / Huang, Zhaocong / Wu, Jing / Zhai, Ya

    ACS applied materials & interfaces

    2024  Volume 16, Issue 15, Page(s) 19764–19770

    Abstract: Two-dimensional van der Waals (2D vdW) materials are widely used in spin-orbit torque (SOT) devices. Recent studies have demonstrated the low crystal symmetry and large spin Hall conductivity of 2D vdW ... ...

    Abstract Two-dimensional van der Waals (2D vdW) materials are widely used in spin-orbit torque (SOT) devices. Recent studies have demonstrated the low crystal symmetry and large spin Hall conductivity of 2D vdW ZrSe
    Language English
    Publishing date 2024-04-05
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.4c00881
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Regulation mechanism of hydrazine and hydroxylamine in nitrogen removal processes: A Comprehensive review.

    Ma, Xin / Feng, Ze-Tong / Zhou, Jia-Min / Sun, Ying-Jun / Zhang, Qian-Qian

    Chemosphere

    2023  Volume 347, Page(s) 140670

    Abstract: As the new fashioned nitrogen removal process, short-cut nitrification and denitrification (SHARON) process, anaerobic ammonium oxidation (anammox) process, completely autotrophic nitrogen removal over nitrite (CANON) process, partial nitrification and ... ...

    Abstract As the new fashioned nitrogen removal process, short-cut nitrification and denitrification (SHARON) process, anaerobic ammonium oxidation (anammox) process, completely autotrophic nitrogen removal over nitrite (CANON) process, partial nitrification and anammox (PN/A) process and partial denitrification and anammox (PD/A) process entered into the public eye due to its advantages of high nitrogen removal efficiency (NRE) and low energy consumption. However, the above process also be limited by long-term start-up time, unstable operation, complicated process regulation and so on. As intermediates or by-metabolites of functional microorganisms in above processes, hydroxylamine (NH
    MeSH term(s) Hydroxylamine ; Denitrification ; Nitrogen ; Oxidation-Reduction ; Bioreactors ; Nitrification ; Hydroxylamines ; Hydrazines ; Sewage
    Chemical Substances Hydroxylamine (2FP81O2L9Z) ; Nitrogen (N762921K75) ; Hydroxylamines ; hydrazine (27RFH0GB4R) ; Hydrazines ; Sewage
    Language English
    Publishing date 2023-11-09
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2023.140670
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Research progress on carotenoid production by Rhodosporidium toruloides.

    Xie, Zhuo-Ting / Mi, Bing-Qian / Lu, Yong-Jun / Chen, Mou-Tong / Ye, Zhi-Wei

    Applied microbiology and biotechnology

    2024  Volume 108, Issue 1, Page(s) 7

    Abstract: Carotenoids are natural lipophilic pigments, which have been proven to provide significant health benefits to humans, relying on their capacity to efficiently scavenge singlet oxygen and peroxyl radicals as antioxidants. Strains belonging to the genus ... ...

    Abstract Carotenoids are natural lipophilic pigments, which have been proven to provide significant health benefits to humans, relying on their capacity to efficiently scavenge singlet oxygen and peroxyl radicals as antioxidants. Strains belonging to the genus Rhodosporidium represent a heterogeneous group known for a number of phenotypic traits including accumulation of carotenoids and lipids and tolerance to heavy metals and oxidative stress. As a representative of these yeasts, Rhodosporidium toruloides naturally produces carotenoids with high antioxidant activity and grows on a wide variety of carbon sources. As a result, R. toruloides is a promising host for the efficient production of more value-added lipophilic compound carotenoids, e.g., torulene and torularhodin. This review provides a comprehensive summary of the research progress on carotenoid biosynthesis in R. toruloides, focusing on the understanding of biosynthetic pathways and the regulation of key enzymes and genes involved in the process. Moreover, the relationship between the accumulation of carotenoids and lipid biosynthesis, as well as the stress from diverse abiotic factors, has also been discussed for the first time. Finally, several feasible strategies have been proposed to promote carotenoid production by R. toruloides. It is possible that R. toruloides may become a critical strain in the production of carotenoids or high-value terpenoids by genetic technologies and optimal fermentation processes. KEY POINTS: • Biosynthetic pathway and its regulation of carotenoids in Rhodosporidium toruloides were concluded • Stimulation of abiotic factors for carotenoid biosynthesis in R. toruloides was summarized • Feasible strategies for increasing carotenoid production by R. toruloides were proposed.
    MeSH term(s) Humans ; Carotenoids/metabolism ; Rhodotorula/genetics ; Yeasts/metabolism ; Biosynthetic Pathways
    Chemical Substances Carotenoids (36-88-4)
    Language English
    Publishing date 2024-01-03
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 392453-1
    ISSN 1432-0614 ; 0171-1741 ; 0175-7598
    ISSN (online) 1432-0614
    ISSN 0171-1741 ; 0175-7598
    DOI 10.1007/s00253-023-12943-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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