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Article ; Online: Examining the Psychometric Properties of the Taiwanese Version of the Hospice Quality of Life Index.

Longcoy, Li-Ting H / Tai, Chun-Yi / Dai, Hung-Da / McMillan, Susan C / Doorenbos, Ardith Z

Journal of hospice and palliative nursing : JHPN : the official journal of the Hospice and Palliative Nurses Association

2022 Volume 25, Issue 1, Page(s) E1–E7

Abstract: Quality of life is an important outcome for people with cancer throughout their cancer trajectory. Having a valid and reliable instrument to measure the quality of life is critical. This cross-sectional study examined the psychometric properties of the ... ...

Abstract	Quality of life is an important outcome for people with cancer throughout their cancer trajectory. Having a valid and reliable instrument to measure the quality of life is critical. This cross-sectional study examined the psychometric properties of the Taiwanese version of the Hospice Quality of Life Index among patients with advanced cancer in Taiwan. There were 3 phases: (1) translation of the Hospice Quality of Life Index from English to Mandarin, (2) pilot testing among 30 targeted participants, and (3) field testing to examine validity and reliability. The results of confirmatory factor analysis indicated that the original factor structure of the Hospice Quality of Life Index did not fit the data. After 5 items were deleted from the original questionnaire, principal factor extraction with oblique rotation for exploratory factor analysis yielded 3 subscales: Social/Spiritual Well-Being, Psychological Well-Being, and Functional/Physiological Well-Being. For convergent validity, the small to moderate strength of associations showed shared variance with the Memorial Symptom Assessment Scale. The internal consistency was supported by Cronbach α ranging from 0.77 to 0.86. This study shows early evidence that the quality of life of people with advanced cancer can be appropriately assessed by the Taiwanese Hospice Quality of Life Index.
MeSH term(s)	Humans ; Psychometrics ; Quality of Life/psychology ; Hospices ; Cross-Sectional Studies ; Reproducibility of Results ; Neoplasms/complications ; Neoplasms/psychology
Language	English
Publishing date	2022-09-27
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2070862-2
ISSN	1539-0705 ; 1522-2179
ISSN (online)	1539-0705
ISSN	1522-2179
DOI	10.1097/NJH.0000000000000911
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Mutual Effects of Depression on Quality of Life in Patients and Family Caregivers.

Huang, Li-Ting / McMillan, Susan C

Oncology nursing forum

2019 Volume 46, Issue 2, Page(s) 208–216

Abstract: Objectives: To elucidate the importance of mutual effects within dyads by examining the contribution of depression on quality of life (QOL) in patients with advanced cancer and their family caregivers (FCs).: Sample & setting: 716 patients with ... ...

Abstract	Objectives: To elucidate the importance of mutual effects within dyads by examining the contribution of depression on quality of life (QOL) in patients with advanced cancer and their family caregivers (FCs). Sample & setting: 716 patients with advanced cancer paired with their FCs at two large, private not-for-profit hospices. Methods & variables: A descriptive, cross-sectional design with the baseline data of a randomized hospice clinical trial was used. Structural equation modeling helped examine four hypotheses by integrating the features of the Actor-Partner Interdependence Model. Variables included QOL and depression. Results: Depression in patients with cancer and their FCs exhibited significant actor effects on an individual's QOL after controlling for the partner effects. Among the spousal pairs, depression in FCs exhibited a positive partner effect on the functional well-being of patients with cancer, indicating that depressive symptoms occurring in FCs may increase patients' functional well-being. Implications for nursing: This study suggests the importance of consistent assessment in emotional well-being for dyads with cancer because their concerns may be transmitted to each other.
MeSH term(s)	Adaptation, Psychological ; Adult ; Aged ; Aged, 80 and over ; Anxiety/psychology ; Caregivers/psychology ; Cross-Sectional Studies ; Depression/psychology ; Family/psychology ; Female ; Humans ; Male ; Middle Aged ; Neoplasms/psychology ; Patients/psychology ; Quality of Life/psychology
Language	English
Publishing date	2019-02-15
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	604886-9
ISSN	1538-0688 ; 0190-535X ; 1538-0688
ISSN (online)	1538-0688 ; 0190-535X
ISSN	1538-0688
DOI	10.1188/19.ONF.208-216
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 1818: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: An Academic Perspective on Publishing in Oncology Nursing.

Tofthagen, Cindy / McMillan, Susan C

Seminars in oncology nursing

2018 Volume 34, Issue 4, Page(s) 393–401

Abstract: Objectives: To describe authorship opportunities for nursing students, encourage writing for publication, and provide practical guidance on reformatting a "school" paper into a version suitable for publication.: Data sources: Published literature, ... ...

Abstract	Objectives: To describe authorship opportunities for nursing students, encourage writing for publication, and provide practical guidance on reformatting a "school" paper into a version suitable for publication. Data sources: Published literature, authors' experience. Conclusion: Nursing students have unique opportunities to write for publication during, and beyond, their educational programs. Writing for publication can be a very rewarding experience and a meaningful one, as nurse authors contribute to the body of knowledge of oncology nursing. Implications for nursing: While an excellent paper written for a class, thesis, final project, or dissertation is virtually never publishable without substantial changes, by following the guidance provided in this article, publication is very possible.
MeSH term(s)	Academies and Institutes ; Guidelines as Topic ; Humans ; Nursing Research/standards ; Oncology Nursing ; Publishing/standards ; Research Report/standards ; Students, Nursing ; Writing/standards
Language	English
Publishing date	2018-09-27
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	632682-1
ISSN	1878-3449 ; 0749-2081
ISSN (online)	1878-3449
ISSN	0749-2081
DOI	10.1016/j.soncn.2018.09.008
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Article ; Online: The Mutual Effects of Perceived Spiritual Needs on Quality of Life in Patients With Advanced Cancer and Family Caregivers.

Huang, Li-Ting / Tai, Chun-Yi / Longcoy, Joshua / McMillan, Susan C

Journal of hospice and palliative nursing : JHPN : the official journal of the Hospice and Palliative Nurses Association

2021 Volume 23, Issue 4, Page(s) 323–330

Abstract: Perceived spiritual needs may increase when patients with advanced cancer and their family caregivers are confronted with the challenges of physical and psychological distress. Given the intertwined relationships between patients and family caregivers, ... ...

Abstract	Perceived spiritual needs may increase when patients with advanced cancer and their family caregivers are confronted with the challenges of physical and psychological distress. Given the intertwined relationships between patients and family caregivers, their interdependence should be considered to understand how perceived spiritual needs affect the quality of life of their own and of their partner. This study used the Actor-Partner Interdependence Model as the conceptual model to investigate the mutual effects of perceived spiritual needs on the quality of life in patients with advanced cancer and their family caregivers after being admitted to hospice. This cross-sectional study used the baseline data of a large clinical trial and identified that patients with cancer and their family caregivers perceived similar spiritual needs associated with the community and outlook needs and had fewer unmet spiritual needs. After controlling for partner effects, perceived outlook needs shown in patients significantly predicted their own functional well-being and social/spiritual well-being. Outlook and community needs perceived by family caregivers also significantly predicted their own mental health. Although partner effects were not shown as expected, the findings provide insight into the mutuality of spirituality and demonstrate the necessity of providing timely and ongoing spiritual assessment and care.
MeSH term(s)	Caregivers ; Cross-Sectional Studies ; Humans ; Neoplasms ; Quality of Life ; Spirituality
Language	English
Publishing date	2021-06-26
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2070862-2
ISSN	1539-0705 ; 1522-2179
ISSN (online)	1539-0705
ISSN	1522-2179
DOI	10.1097/NJH.0000000000000758
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Article ; Online: Fatigue-related symptom clusters and functional status of older adults in hospice.

Abduljawad, Suzan F / Beckstead, Jason W / Dobbs, Debra / Visovsky, Constance / Rodriguez, Carmen S / McMillan, Susan C / Wang, Hsiao Lan

Palliative & supportive care

2022 Volume 21, Issue 1, Page(s) 57–64

Abstract: Background: Fatigue is frequently co-existing with other symptoms and is highly prevalent among patients with cancer and geriatric population. There was a lack of knowledge that focus on fatigue clusters in older adults with cancer in hospice care.: ... ...

Abstract	Background: Fatigue is frequently co-existing with other symptoms and is highly prevalent among patients with cancer and geriatric population. There was a lack of knowledge that focus on fatigue clusters in older adults with cancer in hospice care. Objectives: To identify fatigue-related symptom clusters in older adult hospice patients and discover to what extent fatigue-related symptom clusters predict functional status while controlling for depression. Method: This was a cross-sectional study in a sample of 519 older adult hospice patients with cancer, who completed the Memorial Symptom Assessment Scale, the Center for Epidemiological Studies Depression, Boston Short Form Scale, and the Palliative Performance Scale. Data from a multi-center symptom trial were extracted for this secondary analysis using exploratory factor analysis and hierarchical multiple regression analysis. Results: Data from 519 patients (78 ± 7 years) with terminal cancer who received hospice care under home healthcare services revealed that 39% of the participants experienced fatigue-related symptom clusters (lack of energy, feeling drowsy, and lack of appetite). The fatigue cluster was significantly associated positively with depression ( Conclusion: Older adult hospice patients with cancer experienced various concurrent symptoms. The fatigue-specific symptom cluster was identified significantly associated with depression and predicted functional status. Fatigue should be routinely monitored in older adults, especially among hospice cancer patients, to help reduce psychological distress and prevent functional decline.
MeSH term(s)	Humans ; Aged ; Hospice Care ; Hospices ; Syndrome ; Cross-Sectional Studies ; Functional Status ; Neoplasms/complications ; Fatigue/complications ; Quality of Life
Language	English
Publishing date	2022-06-08
Publishing country	England
Document type	Journal Article
ZDB-ID	2454009-2
ISSN	1478-9523 ; 1478-9515
ISSN (online)	1478-9523
ISSN	1478-9515
DOI	10.1017/S1478951522000207
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Zs.A 6697: Show issues

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Article ; Online: Quality of life among women veterans.

Devine, Debbie T / McMillan, Susan C / Kip, Kevin / Powell-Cope, Gail

Journal of the American Association of Nurse Practitioners

2020 Volume 32, Issue 11, Page(s) 745–755

Abstract: Background: Of 23 million US veterans, 2 million are women. Female veterans often have physical and mental health disorders, but only 6.5% use the Veterans Health Administration (VA) system. Health care for women veterans is challenging in a health care ...

Abstract	Background: Of 23 million US veterans, 2 million are women. Female veterans often have physical and mental health disorders, but only 6.5% use the Veterans Health Administration (VA) system. Health care for women veterans is challenging in a health care system unfamiliar with this population. Purpose: The purpose of this study was to investigate how receipt of treatment by female veterans at a VA women's health specialty clinic affected levels of distress, quality of life (QOL), and depression. Methods: A retrospective record review was completed on 51 female veterans between the ages of 40 and 60 years attending a VA clinic. The clinic provides comprehensive women's health services to female veterans. Multiple linear regression models were fit to explore QOL and depression levels with socioeconomic status, parity, years of service, and military sexual trauma (MST). Results: Female veterans had significantly lower baseline scores for QOL than did a comparison group. The only significant predictor associated with higher health-related symptom scores at baseline was a history of MST (β = 0.363; t = 2.44; p = .02). Means and standard deviations for total scores were significantly higher than those of the comparison group. Higher symptom scores indicated lower QOL among female veterans. Implications for practice: Study findings suggested that timely, comprehensive, gender-specific health care can significantly improve overall QOL and depression levels. Nurse practitioners play a leading role in providing primary care to this population with significant potential to impact QOL, depression levels, and overall health of female veterans.
MeSH term(s)	Adult ; Female ; Humans ; Middle Aged ; Quality of Life/psychology ; Retrospective Studies ; United States ; United States Department of Veterans Affairs/organization & administration ; United States Department of Veterans Affairs/statistics & numerical data ; Veterans/psychology ; Veterans/statistics & numerical data
Language	English
Publishing date	2020-07-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	2716317-9
ISSN	2327-6924 ; 1745-7599 ; 2327-6886 ; 1041-2972
ISSN (online)	2327-6924 ; 1745-7599
ISSN	2327-6886 ; 1041-2972
DOI	10.1097/JXX.0000000000000445
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Article: The Physical Health of Patients with Advanced Pancreatic Cancer and the Psychological Health of their Family Caregivers When Newly Enrolled in Hospice.

Sherman, Deborah Witt / McMillan, Susan C

Journal of hospice and palliative nursing : JHPN : the official journal of the Hospice and Palliative Nurses Association

2015 Volume 17, Issue 3, Page(s) 235–241

Language	English
Publishing date	2015-04-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	2070862-2
ISSN	1539-0705 ; 1522-2179
ISSN (online)	1539-0705
ISSN	1522-2179
DOI	10.1097/NJH.0000000000000154
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Article ; Online: Cancer Pain and Quality of Life.

Rodriguez, Carmen / Ji, Ming / Wang, Hsiao-Lan / Padhya, Tapan / McMillan, Susan C

Journal of hospice and palliative nursing : JHPN : the official journal of the Hospice and Palliative Nurses Association

2019 Volume 21, Issue 2, Page(s) 116–123

Abstract: Cancer pain is an unrelenting symptom with the potential to alter the quality of life of patients. To adequately manage pain, nurses caring for cancer patients need to fully understand each patient's pain experience. The purpose of this study was to ... ...

Abstract	Cancer pain is an unrelenting symptom with the potential to alter the quality of life of patients. To adequately manage pain, nurses caring for cancer patients need to fully understand each patient's pain experience. The purpose of this study was to identify the intensity, distress, frequency, or constancy of pain in patients treated for cancer or cancer symptoms and to better understand patient barriers to pain management. This cross-sectional study included patients (N = 105) treated for cancer or cancer symptoms at 2 outpatient medical centers. Assessments included the Pain Barriers Scale, the Cancer Symptom Scale, and the Multidimensional QOL Scale-Cancer. Descriptive statistics and Spearman correlations were used to analyze the data. Sixty-nine percent of patients reported present pain of moderate to severe intensity that caused distress, was frequent/constant, or interfered with their lives. Patients with the greatest pain distress reported the greatest intensity of pain (r = 0.77) and the greatest interference (r = 0.78) with daily lives. Cancer pain was associated with significant distress and interference with life activities and occurred frequently or constantly for many study patients.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Decision Trees ; Female ; Hospice and Palliative Care Nursing ; Humans ; Male ; Middle Aged ; Neoplasms ; Pain Management ; Pain Measurement ; Pain, Intractable/nursing ; Pain, Intractable/psychology ; Quality of Life ; Surveys and Questionnaires
Language	English
Publishing date	2019-02-28
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2070862-2
ISSN	1539-0705 ; 1522-2179
ISSN (online)	1539-0705
ISSN	1522-2179
DOI	10.1097/NJH.0000000000000507
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Article ; Online: Complicated Grief: Risk Factors, Interventions, and Resources for Oncology Nurses.

Tofthagen, Cindy S / Kip, Kevin / Witt, Ann / McMillan, Susan C

Clinical journal of oncology nursing

2017 Volume 21, Issue 3, Page(s) 331–337

Abstract: Background: When a loved one dies of cancer, complicated grief (CG) may occur because of the trauma associated with family caregivers' perceptions of their loved one's suffering, either from advanced cancer or from side effects of cancer treatment. .: ...

Abstract	Background: When a loved one dies of cancer, complicated grief (CG) may occur because of the trauma associated with family caregivers' perceptions of their loved one's suffering, either from advanced cancer or from side effects of cancer treatment. . Objectives: This article provides an overview of CG and existing interventions for family caregivers who may be at risk for CG following the loss of a loved one and the implications for oncology nurses who provide emotional support and guidance. . Methods: Current evidence related to the treatment of CG and information to assist with identification of individuals at risk for CG are presented, as well as resources for oncology nurses who encounter individuals who are at high risk for, or who are experiencing, CG. . Findings: Although therapy interventions for CG have been shown to be effective forms of treatment, these therapies are not widely available and often require an extended treatment period to yield results. Oncology nurses can provide early interventions, such as referrals to supportive care services and mental health professionals to facilitate effective treatment.
Language	English
Publishing date	2017-06-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	2014665-6
ISSN	1538-067X ; 1092-1095
ISSN (online)	1538-067X
ISSN	1092-1095
DOI	10.1188/17.CJON.331-337
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Zs.A 5229: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 390: Show issues

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Article ; Online: Histopathologic brain age estimation via multiple instance learning.

Marx, Gabriel A / Kauffman, Justin / McKenzie, Andrew T / Koenigsberg, Daniel G / McMillan, Cory T / Morgello, Susan / Karlovich, Esma / Insausti, Ricardo / Richardson, Timothy E / Walker, Jamie M / White, Charles L / Babrowicz, Bergan M / Shen, Li / McKee, Ann C / Stein, Thor D / Farrell, Kurt / Crary, John F

Acta neuropathologica

2023 Volume 146, Issue 6, Page(s) 785–802

Abstract: Understanding age acceleration, the discordance between biological and chronological age, in the brain can reveal mechanistic insights into normal physiology as well as elucidate pathological determinants of age-related functional decline and identify ... ...

Abstract	Understanding age acceleration, the discordance between biological and chronological age, in the brain can reveal mechanistic insights into normal physiology as well as elucidate pathological determinants of age-related functional decline and identify early disease changes in the context of Alzheimer's and other disorders. Histopathological whole slide images provide a wealth of pathologic data on the cellular level that can be leveraged to build deep learning models to assess age acceleration. Here, we used a collection of digitized human post-mortem hippocampal sections to develop a histological brain age estimation model. Our model predicted brain age within a mean absolute error of 5.45 ± 0.22 years, with attention weights corresponding to neuroanatomical regions vulnerable to age-related changes. We found that histopathologic brain age acceleration had significant associations with clinical and pathologic outcomes that were not found with epigenetic based measures. Our results indicate that histopathologic brain age is a powerful, independent metric for understanding factors that contribute to brain aging.
MeSH term(s)	Humans ; Child, Preschool ; Aging/pathology ; Brain/pathology ; Epigenomics ; Acceleration ; Autopsy ; Epigenesis, Genetic ; DNA Methylation
Language	English
Publishing date	2023-10-10
Publishing country	Germany
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	1079-0
ISSN	1432-0533 ; 0001-6322
ISSN (online)	1432-0533
ISSN	0001-6322
DOI	10.1007/s00401-023-02636-3
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