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  1. Article ; Online: Meta-Analysis of Physical Training on Natriuretic Peptides and Inflammation in Heart Failure.

    do Nascimento, Daniela Meirelles / Bock, Patrícia Martins / Nemetz, Betina / Goldraich, Livia Adams / Schaan, Beatriz D

    The American journal of cardiology

    2022  Volume 178, Page(s) 60–71

    Abstract: ... in heart failure (HF). We aimed to assess the impact of physical training on B-type natriuretic peptide and N ... natriuretic peptide (p = 0.02), NT-proBNP (p <0.01), C-reactive protein (p <0.00001), TNF-α (p = 0.03), IL-6 (p = 0.04 ... and IL-1β (p = 0.001). Aerobic continuous training was associated with a 35% reduction in NT-proBNP (p ...

    Abstract Physical training has been reported to attenuate myocardial stress and inflammation in heart failure (HF). We aimed to assess the impact of physical training on B-type natriuretic peptide and N-terminal pro-B-type natriuretic peptide (NT-proBNP), as well as biomarkers of inflammation-C-reactive protein, tumor necrosis factor α (TNF-α), and interleukins (ILs). A systematic electronic literature search was conducted up to May 2021 in PubMed, Cochrane Library, CINAHL, Embase, and SPORTDiscus to identify randomized clinical trials reporting associations between any formal physical training intervention and biomarker levels in patients with HF. Random-effects meta-analyses was used to calculate pooled correlations between physical training and blood biomarkers. Biomarker outcomes were expressed as mean difference or ratio of means and 95% confidence interval between the intervention and control groups, according to the normality of the data. A total of 38 trials were included in the final meta-analysis (2,652 randomized patients). Physical training was associated with decreased B-type natriuretic peptide (p = 0.02), NT-proBNP (p <0.01), C-reactive protein (p <0.00001), TNF-α (p = 0.03), IL-6 (p = 0.04), and IL-1β (p = 0.001). Aerobic continuous training was associated with a 35% reduction in NT-proBNP (p = 0.01); ≥150 min/week of exercise was associated with a greater reduction in TNF-α levels (p = 0.0004), and aerobic interval training was associated with lower IL-6 levels (p = 0.01). In conclusion, physical training in patients with HF is associated with beneficial effects on natriuretic peptides and biomarkers of inflammation because they were all reduced by the intervention.
    MeSH term(s) Biomarkers ; C-Reactive Protein/analysis ; Heart Failure/complications ; Humans ; Inflammation ; Interleukin-6 ; Natriuretic Peptide, Brain ; Natriuretic Peptides ; Peptide Fragments ; Tumor Necrosis Factor-alpha
    Chemical Substances Biomarkers ; Interleukin-6 ; Natriuretic Peptides ; Peptide Fragments ; Tumor Necrosis Factor-alpha ; Natriuretic Peptide, Brain (114471-18-0) ; C-Reactive Protein (9007-41-4)
    Language English
    Publishing date 2022-07-08
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Review ; Systematic Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2022.05.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui IV Zs.73: Show issues Location:
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  2. Article: Efficient search procedures for extreme pollutant values.

    Casey, D / Nemetz, P N / Uyeno, D

    Environmental monitoring and assessment

    2013  Volume 5, Issue 2, Page(s) 165–176

    Abstract: Extreme pollutant values are of great interest in water quality monitoring because of their frequent toxicological significance. The principal barrier to the detection of these values, however, is the cost of extensive and comprehensive monitoring. This ... ...

    Abstract Extreme pollutant values are of great interest in water quality monitoring because of their frequent toxicological significance. The principal barrier to the detection of these values, however, is the cost of extensive and comprehensive monitoring. This paper demonstrates an efficient method to determine the maximum sample measurement from a finite set of sequential samples without explicitly testing them all. It is assumed that the process of sample measurement is distinct from collection and has higher costs. It is further assumed that the measurements have high positive autocorrelation.A methodology is presented based on a common industrial testing procedure referred to as composite sampling-the physical pooling or compositing of a set of sequential samples before measurement. A method known as primary first order compositing (PFOC) was found to be superior to the traditional technique of random sampling, particularly if small composite sizes are utilized.
    Language English
    Publishing date 2013-11-21
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 782621-7
    ISSN 1573-2959 ; 0167-6369
    ISSN (online) 1573-2959
    ISSN 0167-6369
    DOI 10.1007/BF00395845
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 5186: Show issues

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  3. Article: Passive smoking results: new risk for active smokers.

    Nemetz, P N

    American journal of public health

    1990  Volume 80, Issue 10, Page(s) 1274

    MeSH term(s) Humans ; Risk Factors ; Smoking ; Tobacco Smoke Pollution
    Chemical Substances Tobacco Smoke Pollution
    Language English
    Publishing date 1990-10
    Publishing country United States
    Document type Letter
    ZDB-ID 121100-6
    ISSN 1541-0048 ; 0090-0036 ; 0002-9572
    ISSN (online) 1541-0048
    ISSN 0090-0036 ; 0002-9572
    DOI 10.2105/ajph.80.10.1274-a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Un I Zs.279: Show issues Location:
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  4. Article ; Online: Medical error and outcomes measures: where have all the autopsies gone?

    Burton, E C / Nemetz, P N

    MedGenMed : Medscape general medicine

    2000  Volume 2, Issue 2, Page(s) E8

    MeSH term(s) Autopsy/statistics & numerical data ; Cause of Death ; Health Services Research/statistics & numerical data ; Humans ; Medical Errors/statistics & numerical data ; Outcome Assessment (Health Care)/standards ; Quality of Health Care/statistics & numerical data ; United States/epidemiology
    Language English
    Publishing date 2000-04-28
    Publishing country UNITED STATES
    Document type Journal Article
    ISSN 1531-0132
    ISSN (online) 1531-0132
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Institutional and economic influences on autopsy performance.

    Burton, E C / Nemetz, P N

    MedGenMed : Medscape general medicine

    2000  Volume 2, Issue 3, Page(s) E51

    MeSH term(s) Autopsy/economics ; Autopsy/statistics & numerical data ; Centers for Medicare and Medicaid Services (U.S.)/economics ; Centers for Medicare and Medicaid Services (U.S.)/legislation & jurisprudence ; Hospital Administration/economics ; Hospital Administration/statistics & numerical data ; Humans ; Insurance Benefits/economics ; Insurance Benefits/statistics & numerical data ; Insurance, Health/economics ; Insurance, Health/statistics & numerical data ; Managed Care Programs/economics ; Managed Care Programs/statistics & numerical data ; Medicare/economics ; Medicare/legislation & jurisprudence ; United States
    Language English
    Publishing date 2000-07-7
    Publishing country UNITED STATES
    Document type Letter
    ISSN 1531-0132
    ISSN (online) 1531-0132
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Choroid, Haller's, and Sattler's layer thickness in intermediate age-related macular degeneration with and without fellow neovascular eyes.

    Esmaeelpour, Marieh / Ansari-Shahrezaei, Siamak / Glittenberg, Carl / Nemetz, Susanne / Kraus, Martin F / Hornegger, Joachim / Fujimoto, James G / Drexler, Wolfgang / Binder, Susanne

    Investigative ophthalmology & visual science

    2014  Volume 55, Issue 8, Page(s) 5074–5080

    Abstract: ... statistically analyzed in 67 subjects consisting of intermediate AMD (n = 21), intermediate AMD (n = 22) with fellow nAMD ... eyes (n = 22), and healthy eyes (n = 24) with no age and axial eye length difference between groups ... of eyes (P > 0.05, ANOVA). Eyes were imaged by a prototype high-speed (60,000 A-scans/s) spectral-domain ...

    Abstract Purpose: To analyze choroidal, Sattler's, and Haller's layer thickness maps in age-related macular degeneration (AMD) patients having eyes with bilateral large drusen and pigment changes (intermediate AMD), in patients having intermediate AMD eyes with neovascular fellow eyes (nAMD), and in healthy subjects using three-dimensional (3D) 1060-nm optical coherence tomography (OCT).
    Methods: Automatically generated choroidal thickness (ChT), retinal thickness, and Sattler's and Haller's layer thickness maps were statistically analyzed in 67 subjects consisting of intermediate AMD (n = 21), intermediate AMD (n = 22) with fellow nAMD eyes (n = 22), and healthy eyes (n = 24) with no age and axial eye length difference between groups of eyes (P > 0.05, ANOVA). Eyes were imaged by a prototype high-speed (60,000 A-scans/s) spectral-domain 3D 1060-nm OCT over a 36° × 36° field of view.
    Results: The mean ± SD (μm) subfoveal ChT for healthy subjects and for bilateral intermediate AMD, unilateral intermediate AMD, and their nAMD fellow eyes was 259 ± 95 and 222 ± 98, 149 ± 60, and 171 ± 78, respectively. Choroidal thickness maps demonstrated significant submacular thinning in unilateral intermediate AMD in comparison to healthy and bilateral intermediate AMD eyes (P < 0.001, ANOVA, post hoc P < 0.001 and P < 0.05, respectively). Sattler's and Haller's layers were thinnest in intermediate AMDs that presented with nAMD fellow eyes (Kruskal-Wallis test P < 0.01). For the choroid and its sublayers, there was no difference between the intermediate AMD eyes and their fellow nAMD eyes (paired testing, P < 0.05).
    Conclusions: The 3D 1060-nm OCT choroidal imaging visualized significant changes in choroidal, Sattler's, and Haller's layer thickness in relation to the progression of AMD. This may be important for understanding the choroidopathy in the pathophysiology of AMD.
    MeSH term(s) Aged ; Aged, 80 and over ; Choroid/pathology ; Choroidal Neovascularization/complications ; Choroidal Neovascularization/pathology ; Disease Progression ; Female ; Follow-Up Studies ; Humans ; Imaging, Three-Dimensional ; Macular Degeneration/complications ; Macular Degeneration/pathology ; Male ; Middle Aged ; Prospective Studies ; Retina/pathology ; Retinal Neovascularization/complications ; Retinal Neovascularization/pathology ; Tomography, Optical Coherence/methods
    Language English
    Publishing date 2014-07-22
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 391794-0
    ISSN 1552-5783 ; 0146-0404
    ISSN (online) 1552-5783
    ISSN 0146-0404
    DOI 10.1167/iovs.14-14646
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 45: Show issues Location:
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  7. Article ; Online: Attitudes toward the autopsy--an 8-state survey.

    Nemetz, Peter N / Tanglos, Eric / Sands, Laura P / Fisher, William P / Newman, William P / Burton, Elizabeth C

    MedGenMed : Medscape general medicine

    2006  Volume 8, Issue 3, Page(s) 80

    Abstract: Context: National autopsy rates have declined for several decades, and the reasons for such decline remain contentious.: Objective: To elicit the opinions of one group of crucial decision makers as to the reasons for this decline and possible modes ... ...

    Abstract Context: National autopsy rates have declined for several decades, and the reasons for such decline remain contentious.
    Objective: To elicit the opinions of one group of crucial decision makers as to the reasons for this decline and possible modes of reversal.
    Design: A 2-part survey, composed of multiple choice questions and questions requesting specific data on autopsy rates and costs.
    Setting: Illinois, Iowa, Louisiana, Minnesota, Nebraska, North Dakota, South Dakota, and Wisconsin.
    Participants: Hospital administrators within the 8 states.
    Main outcome measures: Six-point survey scale relating to reasons for autopsy decline and possible remedial measures, as well as estimates of autopsy rates and costs.
    Results: The response rate was 43% and the median autopsy rate was 2.4% (mean 6.1%). The median cost of autopsy was estimated at $852 (mean $1275). Larger hospitals were associated with higher autopsy rates than smaller hospitals (9.6% vs 4.0%), and teaching hospitals had a significantly higher autopsy rate than nonteaching institutions (11.4% vs 3.8%). Autopsy rates also varied by type of hospital control, with federal government hospitals having the highest autopsy rate at 15.1%. Sixty-six percent of all respondents agreed that current autopsy rates were adequate. Of the respondents, the highest percent (86%) agreed that improved diagnostics contributed to the decline in autopsies, and the highest percent (78%) agreed that direct payment to pathologists for autopsies under the physician fee schedule might lead to an increase in autopsies.
    Conclusions: Our data support the conclusion that the decline in autopsy performance is multifactorial, although the variable that dominates in this analysis is the contentious perception that improved diagnostic technology renders the autopsy redundant. The rate of autopsy is conditional, at least in part, on individual hospital characteristics such as large hospital size, teaching status, and federal ownership. Three underlying factors may explain these associations: resources, mission, and case mix. An important factor in declining autopsy rates appears to be the changing economic landscape, with its increased focus on cost control within both the public and private healthcare sectors.
    MeSH term(s) Attitude of Health Personnel ; Autopsy/statistics & numerical data ; Data Collection ; Hospital Administrators/psychology ; Hospitals/statistics & numerical data ; Humans
    Language English
    Publishing date 2006-09-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2041637-4
    ISSN 1531-0132 ; 1531-0132
    ISSN (online) 1531-0132
    ISSN 1531-0132
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  8. Journal: System Solutions to Urban Wastewater Control

    Nemetz, P.N.

    Journal of Environmental Economics and Management

    1980  Volume 7, Page(s) 108–122

    Keywords Siedlungsabwasser ; Siedlungswasserwirtschaft ; Abwasserbeseitigungsplan ; Kostensenkung ; Kosten-Wirksamkeits-Analyse ; Umweltschutzkosten ; Materialbilanz ; Abwasserbehandlung ; Brauerei ; Standortwahl ; Industriestandort ; Klaeranlage ; Optimierungsmodell ; Systemanalyse
    Language English
    Document type Journal
    Database OPAC and Environmental database (ULIDAT) of The Federal Environment Agency (UBA)

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  9. Article: Contributions of autopsy to population-based cancer epidemiology: targetted intervention to improve ascertainment.

    Chute, C G / Ballard, D J / Nemetz, P N

    IARC scientific publications

    1991  , Issue 112, Page(s) 207–216

    Abstract: The importance of autopsy data in cancer epidemiological investigation is well appreciated by researchers at the Mayo Clinic. The Rochester Epidemiology Program Project is a complete population-based collection of morbidity and mortality data in Olmsted ... ...

    Abstract The importance of autopsy data in cancer epidemiological investigation is well appreciated by researchers at the Mayo Clinic. The Rochester Epidemiology Program Project is a complete population-based collection of morbidity and mortality data in Olmsted County, Minnesota (population, 100,000), funded by the National Institutes of Health since 1964. Comprehensive ascertainment of cancer in this community cohort has been augmented by initial diagnosis at autopsy for 12% of colorectal cancers, 35% of intracranial neoplasms, 45% of phaeochromocytomas and 37% of renal-cell carcinomas. These rates are in stark contrast to autopsy diagnoses in our cancer registry--usually less than 1%. The difference is attributable to the denominator in these comparisons, a concept of vital importance to the epidemiological interpretation of autopsy findings. Despite the enormous value of the autopsy in our research, social and economic factors diminished autoptic rates in Olmsted County from 63% in 1970 to 39% in 1984. These rates are well above that for the USA as a whole but parallel our national decline in frequency of autopsy. The major factors responsible for this reduction appear to be the increasing proportion of deaths in nursing homes and the advent of declining reimbursement in US health care.
    MeSH term(s) Autopsy ; Humans ; Incidence ; Minnesota/epidemiology ; Neoplasms/epidemiology ; Population Surveillance ; Registries
    Language English
    Publishing date 1991
    Publishing country France
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S. ; Review
    ISSN 0300-5038
    ISSN 0300-5038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Threat in opportunity and opportunity in threat

    Nemetz, Peter N

    The Journal of energy and development Vol. 9, No. 2 , p. 263-288

    energy prospects for Australia and New Zealand

    1984  Volume 9, Issue 2, Page(s) 263–288

    Author's details [von] Peter N. Nemetz [u.a.]
    Keywords Energiepolitik ; Australien ; Neuseeland
    Publishing place Boulder, Colo.
    Document type Article
    ZDB-ID 197377-0
    Database ECONomics Information System

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