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  1. Article ; Online: SARS-CoV-2 and the human-animal interface: outbreaks on mink farms.

    Koopmans, Marion

    The Lancet. Infectious diseases

    2020  Volume 21, Issue 1, Page(s) 18–19

    MeSH term(s) Animals ; COVID-19/epidemiology ; COVID-19/transmission ; COVID-19/veterinary ; Denmark ; Disease Outbreaks ; Farms ; Humans ; Mink/virology ; SARS-CoV-2 ; Zoonoses/transmission
    Language English
    Publishing date 2020-11-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(20)30912-9
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    Zs.A 5743: Show issues Location:
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  2. Book ; Online: Air pollution and COVID-19

    Brunekreff, Bert / Downward, George / Forastiere, Francesco / Gehring, Ulrike / Heederik, Dick J. J. / Hoek, Gerard / Koopmans, Marion P. G. / Smit, Lidwien A. M. / Vermeulen, Roel C. H.

    including elements of air pollution in rural areas, indoor air pollution and vulnerability and resilience aspects of our society against respiratory disease, social inequality stemming from air pollution

    2021  

    Abstract: This study is about the effects of air pollution on health, notably COVID-19. The COVID-19 pandemic continues to wreak havoc in many areas of the world. The infection spreads through person-to-person contact. Transmission and prognosis, once infected, ... ...

    Institution Europäisches Parlament
    Author's details Policy Department for Economic, Scientific and Quality of Life Policies, European Parliament ; Bert Brunekreef, Utrecht University, Utrecht, The Netherlands, George Downward, Utrecht University and University Medical Centre, Utrecht, The Netherlands, Francesco Forastiere, National Research Council (CNR), Italy and Imperial College, London, UK, Ulrike Gehring, Utrecht University, Utrecht, The Netherlands, Dick J. J. Heederik, Utrecht University, Utrecht, The Netherlands, Gerard Hoek, Utrecht University, Utrecht, The Netherlands, Marion P. G. Koopmans, Erasmus Medical Centre, Rotterdam, The Netherlands, Lidwien A. M. Smit, Utrecht University, Utrecht, The Netherlands, Roel C. H. Vermeulen, Utrecht University and University Medical Centre, Utrecht, The Netherlands
    Abstract This study is about the effects of air pollution on health, notably COVID-19. The COVID-19 pandemic continues to wreak havoc in many areas of the world. The infection spreads through person-to-person contact. Transmission and prognosis, once infected, are potentially influenced by many factors, including air pollution. Studies have suggested that air pollution increases the incidence and the severity of the disease. However, the current data are too limited to be certain. Especially the quantitative contribution of air pollution to the disease is still very uncertain. This document was provided by the Policy Department for Economic, Scientific and Quality of Life Policies at the request of the committee on the Environment, Public Health and Food Safety (ENVI).
    Language English
    Size 1 Online-Ressource(66 Seiten)
    Edition PE 658.216 - January 2021
    Publisher European Parliament
    Publishing place Luxembourg
    Publishing country Luxembourg
    Document type Book ; Online
    Note Manuscript completed: December 2020 ; Open Access
    HBZ-ID HT020703585
    ISBN 978-92-846-7669-9 ; 92-846-7669-X
    DOI 10.2861/46029
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Tracking SARS-CoV-2 variants and resources.

    Oude Munnink, Bas B / Koopmans, Marion

    Nature methods

    2023  Volume 20, Issue 4, Page(s) 489–490

    MeSH term(s) Humans ; COVID-19 ; SARS-CoV-2
    Language English
    Publishing date 2023-03-15
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2169522-2
    ISSN 1548-7105 ; 1548-7091
    ISSN (online) 1548-7105
    ISSN 1548-7091
    DOI 10.1038/s41592-023-01833-y
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  4. Article ; Online: Being ready for the next influenza pandemic?

    Kuiken, Thijs / Fouchier, Ron A M / Koopmans, Marion P G

    The Lancet. Infectious diseases

    2023  Volume 23, Issue 4, Page(s) 398–399

    MeSH term(s) Humans ; Influenza, Human/epidemiology ; Influenza, Human/prevention & control ; Pandemics/prevention & control ; Disease Outbreaks ; Influenza A virus ; Influenza Vaccines
    Chemical Substances Influenza Vaccines
    Language English
    Publishing date 2023-03-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(23)00117-2
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  5. Article ; Conference proceedings: Selected papers from the ESCV and ESVV joint symposium on zoonoses in Madrid

    Koopmans, Maria Petronella Gerarda

    Journal of clinical virology 58 ,2, S. 341 - 362

    [7 September 2012]

    2013  

    Institution European Society of Veterinary Cardiology
    European Society for Veterinary Virology
    Author's details guest ed.: Marion Koopmans
    Collection Journal of clinical virology
    Language English
    Publishing place Amsterdam [u.a.]
    Publishing country Netherlands
    Document type Article ; Conference proceedings
    HBZ-ID HT017812604
    Database Catalogue ZB MED Medicine, Health

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    Zs A 3790 -58-

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  6. Article ; Online: A Journey to the Central Nervous System: Routes of Flaviviral Neuroinvasion in Human Disease.

    Marshall, Eleanor M / Koopmans, Marion P G / Rockx, Barry

    Viruses

    2022  Volume 14, Issue 10

    Abstract: Many arboviruses, including viruses of ... ...

    Abstract Many arboviruses, including viruses of the
    MeSH term(s) Humans ; Flavivirus/physiology ; Central Nervous System ; Blood-Brain Barrier ; Arboviruses ; Antiviral Agents ; Vaccines
    Chemical Substances Antiviral Agents ; Vaccines
    Language English
    Publishing date 2022-09-21
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v14102096
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  7. Article ; Online: Spreading of SARS-CoV-2 from hamsters to humans.

    Haagmans, Bart L / Koopmans, Marion P G

    Lancet (London, England)

    2022  Volume 399, Issue 10329, Page(s) 1027–1028

    MeSH term(s) Animals ; Antibodies, Viral ; COVID-19 ; Cricetinae ; Humans ; Lung ; SARS-CoV-2
    Chemical Substances Antibodies, Viral
    Language English
    Publishing date 2022-03-09
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(22)00423-8
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  8. Article ; Online: Clinical evaluation of the Roche distributed SD Biosensor SARS-CoV-2 & Flu A/B Rapid Antigen Test amongst mild symptomatic people during the 2022/2023 winter season.

    Igloi, Zsofia / Velzing, Jans / Koopmans, Marion / Molenkamp, Richard

    medRxiv

    Abstract: Both influenza and SARS-CoV-2 are seasonal respiratory illnesses with similar symptoms, however distinguishing one from the other can have benefits for the patient and have different implications in various settings. In this study we have evaluated the ... ...

    Abstract Both influenza and SARS-CoV-2 are seasonal respiratory illnesses with similar symptoms, however distinguishing one from the other can have benefits for the patient and have different implications in various settings. In this study we have evaluated the clinical performance of the Roche distributed SD Biosensor SARS-CoV-2 & Flu A/B Rapid Antigen Test during the 2022/2023 winter season, in a non-hospitalized, mild symptomatic population, comparing results with reverse transcription quantitative polymerase chain reaction (RT-qPCR). Participants also filled in a short questionnaire about their symptom onset, symptoms, vaccination status for both influenza and SARS-CoV-2. We could include 290 people with complete records with female majority (72%, 209/290). Age ranged from 18 years old (minimum age for inclusion) to 71 years (mean age was 40.4 years). From the 290 inclusions 93 tested positive with SARS-CoV-2 PCR, 12 by influenza A and 6 by influenza B PCR. For SARS-CoV-2 overall sensitivity was 72.0% (confidence interval, CI 61.8-80.9%) and specificity 99.5% (CI 97.2-99.9%). SARS-CoV-2 RDT performed best up to and including PCR ct value of 25 (sensitivity 96% CI 85.8-99.5%), but could also detect samples less or equal to PCR ct 33, however with lower sensitivity (sensitivity 80.0% CI 69.6-88.1%). For influenza limited amount of samples were available; the RDT detected influenza A with 58.3% sensitivity (CI 27.7-84.8) and 100% specificity (CI 98.6-100.0%). In case of influenza B the inclusions were too low to calculate sensitivity reliably (2/6, 33.3% CI 4.3-77.7%); specificity was 98.2% (5/274, CI 95.8-99.4%). No cross reaction between SARS-CoV-2 and Flu A/B was experienced. As was shown before, SARS-CoV-2 could be determined with high sensitivity in recent onset and lower than ct 25 samples. In spite of performing the study throughout the influenza season, we had sub optimal inclusions for determining RDT clinical performance; further studies are needed.
    Keywords covid19
    Language English
    Publishing date 2024-02-06
    Publisher Cold Spring Harbor Laboratory Press
    Document type Article ; Online
    DOI 10.1101/2024.02.05.24302338
    Database COVID19

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  9. Article ; Online: Clinical evaluation of the Roche distributed SD Biosensor SARS-CoV-2 & Flu A/B Rapid Antigen Test amongst mild symptomatic people during the 2022/2023 winter season

    Iglὁi, Zsὁfia / Velzing, Jans / Koopmans, Marion / Molenkamp, Richard

    medRxiv

    Abstract: Both influenza and SARS-CoV-2 are seasonal respiratory illnesses with similar symptoms, however distinguishing one from the other can have benefits for the patient and have different implications in various settings. In this study we have evaluated the ... ...

    Abstract Both influenza and SARS-CoV-2 are seasonal respiratory illnesses with similar symptoms, however distinguishing one from the other can have benefits for the patient and have different implications in various settings. In this study we have evaluated the clinical performance of the Roche distributed SD Biosensor SARS-CoV-2 & Flu A/B Rapid Antigen Test during the 2022/2023 winter season, in a non-hospitalized, mild symptomatic population, comparing results with reverse transcription quantitative polymerase chain reaction (RT-qPCR). Participants also filled in a short questionnaire about their symptom onset, symptoms, vaccination status for both influenza and SARS-CoV-2. We could include 290 people with complete records with female majority (72%, 209/290). Age ranged from 18 years old (minimum age for inclusion) to 71 years (mean age was 40.4 years). From the 290 inclusions 93 tested positive with SARS-CoV-2 PCR, 12 by influenza A and 6 by influenza B PCR. For SARS-CoV-2 overall sensitivity was 72.0% (confidence interval, CI 61.8-80.9%) and specificity 99.5% (CI 97.2-99.9%). SARS-CoV-2 RDT performed best up to and including PCR ct value of 25 (sensitivity 96% CI 85.8-99.5%), but could also detect samples less or equal to PCR ct 33, however with lower sensitivity (sensitivity 80.0% CI 69.6-88.1%). For influenza limited amount of samples were available; the RDT detected influenza A with 58.3% sensitivity (CI 27.7-84.8) and 100% specificity (CI 98.6-100.0%). In case of influenza B the inclusions were too low to calculate sensitivity reliably (2/6, 33.3% CI 4.3-77.7%); specificity was 98.2% (5/274, CI 95.8-99.4%). No cross reaction between SARS-CoV-2 and Flu A/B was experienced. As was shown before, SARS-CoV-2 could be determined with high sensitivity in recent onset and lower than ct 25 samples. In spite of performing the study throughout the influenza season, we had sub optimal inclusions for determining RDT clinical performance; further studies are needed.
    Keywords covid19
    Language English
    Publishing date 2024-02-06
    Publisher Cold Spring Harbor Laboratory Press
    Document type Article ; Online
    DOI 10.1101/2024.02.05.24302338
    Database COVID19

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  10. Article: The pathogenesis of zoonotic viral infections: Lessons learned by studying reservoir hosts.

    Begeman, Lineke / van Riel, Debby / Koopmans, Marion P G / Kuiken, Thijs

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1151524

    Abstract: Zoonotic viral infections that cause severe disease or even death in some people may be asymptomatic or mild in reservoir hosts. Comparison of the pathogenesis of these two host categories may potentially explain the difference in disease. However, ... ...

    Abstract Zoonotic viral infections that cause severe disease or even death in some people may be asymptomatic or mild in reservoir hosts. Comparison of the pathogenesis of these two host categories may potentially explain the difference in disease. However, infections in reservoir hosts are often neglected. Therefore, we compared the pathogenesis of rabies virus, macacine alphaherpesvirus, West Nile virus, Puumala orthohantavirus, monkeypox virus, Lassa mammarenavirus, H5N1 highly pathogenic avian influenza, Marburg virus, Nipah virus, Middle East respiratory syndrome, and simian/human immunodeficiency viruses in both humans and reservoir hosts. We showed that most aspects of the pathogeneses were remarkably similar. The remaining differences lead to the identification of tipping points in the pathogeneses that are important for explaining the disease outcome in severe human cases. Further elucidating these tipping points by studying zoonotic viral infections in their reservoir hosts may teach us how to reduce the severity of zoonotic viral diseases in humans.
    Language English
    Publishing date 2023-03-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1151524
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