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Article ; Online: Varicella Vaccine-Induced Infantile Zoster-Like Skin Rash.

Sugai, Tatsuro / Fujita, Yasuyuki / Yamada, Souichi / Fukushi, Shuetsu / Inamura, Emi / Hatakeyama, Kinya / Shimizu, Satoko

The Journal of pediatrics

2022 Volume 251, Page(s) 218–219

MeSH term(s)	Humans ; Chickenpox/prevention & control ; Chickenpox Vaccine/adverse effects ; Exanthema/etiology ; Herpes Zoster ; Vaccines, Attenuated
Chemical Substances	Chickenpox Vaccine ; Vaccines, Attenuated
Language	English
Publishing date	2022-08-23
Publishing country	United States
Document type	Case Reports
ZDB-ID	3102-1
ISSN	1097-6833 ; 0022-3476
ISSN (online)	1097-6833
ISSN	0022-3476
DOI	10.1016/j.jpeds.2022.08.032
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Article ; Online: Macacine alphaherpesvirus 1 (B Virus) Infection in Humans, Japan, 2019

Souichi Yamada / Harutaka Katano / Yuko Sato / Tadaki Suzuki / Akihiko Uda / Keita Ishijima / Motoi Suzuki / Daigo Yamada / Shizuko Harada / Hitomi Kinoshita / Phu Hoang Anh Nguyen / Hideki Ebihara / Ken Maeda / Masayuki Saijo / Shuetsu Fukushi

Emerging Infectious Diseases, Vol 30, Iss 1, Pp 177-

2024 Volume 179

Abstract: Two human patients with Macacine alphaherpesvirus 1 infection were identified in Japan in 2019. Both patients had worked at the same company, which had a macaque facility. The rhesus-genotype B virus genome was detected in cerebrospinal fluid samples ... ...

Abstract	Two human patients with Macacine alphaherpesvirus 1 infection were identified in Japan in 2019. Both patients had worked at the same company, which had a macaque facility. The rhesus-genotype B virus genome was detected in cerebrospinal fluid samples from both patients.
Keywords	Macacine alphaherpesvirus 1 ; B virus ; viruses ; zoonoses ; Japan ; Medicine ; R ; Infectious and parasitic diseases ; RC109-216
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	Centers for Disease Control and Prevention
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Macacine alphaherpesvirus 1 (B Virus) Infection in Humans, Japan, 2019.

Yamada, Souichi / Katano, Harutaka / Sato, Yuko / Suzuki, Tadaki / Uda, Akihiko / Ishijima, Keita / Suzuki, Motoi / Yamada, Daigo / Harada, Shizuko / Kinoshita, Hitomi / Nguyen, Phu Hoang Anh / Ebihara, Hideki / Maeda, Ken / Saijo, Masayuki / Fukushi, Shuetsu

Emerging infectious diseases

2023 Volume 30, Issue 1, Page(s) 177–179

Abstract	Two human patients with Macacine alphaherpesvirus 1 infection were identified in Japan in 2019. Both patients had worked at the same company, which had a macaque facility. The rhesus-genotype B virus genome was detected in cerebrospinal fluid samples from both patients.
MeSH term(s)	Animals ; Humans ; Herpesvirus 1, Cercopithecine ; Japan/epidemiology ; Macaca mulatta ; Genotype ; Monkey Diseases
Language	English
Publishing date	2023-12-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	1380686-5
ISSN	1080-6059 ; 1080-6040
ISSN (online)	1080-6059
ISSN	1080-6040
DOI	10.3201/eid3001.230435
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Article ; Online: OLIG2 translocates to chromosomes during mitosis via a temperature downshift: A novel neural cold response of mitotic bookmarking.

Hayashi, Shinichi / Seki-Omura, Ryohei / Yamada, Shintaro / Kamata, Taito / Sato, Yuki / Oe, Souichi / Koike, Taro / Nakano, Yousuke / Iwashita, Hikaru / Hirahara, Yukie / Tanaka, Susumu / Sekijima, Tsuneo / Ito, Takeshi / Yasukochi, Yoshiki / Higasa, Koichiro / Kitada, Masaaki

Gene

2023 Volume 891, Page(s) 147829

MeSH term(s)	Temperature ; Chromosomes ; Mitosis ; Chromatin
Chemical Substances	Chromatin
Language	English
Publishing date	2023-09-23
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	391792-7
ISSN	1879-0038 ; 0378-1119
ISSN (online)	1879-0038
ISSN	0378-1119
DOI	10.1016/j.gene.2023.147829
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Article ; Online: Regulatory non-coding RNAs in nervous system development and disease.

Oe, Souichi / Kimura, Tominori / Yamada, Hisao

Frontiers in bioscience (Landmark edition)

2019 Volume 24, Issue 7, Page(s) 1203–1240

Abstract: Recent evidence demonstrates that long non-coding RNAs (lncRNAs) regulate the expression of multiple genes in an epigenetic, transcriptional, or post-transcriptional manner. They are involved in various cellular phenomena, such as the recruitment of ... ...

Abstract	Recent evidence demonstrates that long non-coding RNAs (lncRNAs) regulate the expression of multiple genes in an epigenetic, transcriptional, or post-transcriptional manner. They are involved in various cellular phenomena, such as the recruitment of transcription factors, epigenetic chaperoning, control of alternative splicing, mRNA stability and translational activity, as well as acting as decoys against microRNAs. In this review, we summarize the pivotal roles of lncRNAs in regulation of the gene expression involved in neural cell differentiation, synaptogenesis and synaptic plasticity in the central nervous system (CNS). We also describe the aberrant expression of multiple lncRNAs involved in the pathogenesis of neurological diseases. The abnormal expression of lncRNAs leads to altered expression levels of target genes, which contributes to neurodegenerative diseases, such as in Alzheimer's disease and Parkinson's disease, and to the formation of tumors, such as glioma. Accordingly, we discuss recent findings for the modes of action of lncRNAs in normal CNS development and for aberrant lncRNA actions in the pathogenesis of neuronal diseases.
MeSH term(s)	Alzheimer Disease/genetics ; Cell Differentiation/genetics ; Central Nervous System/growth & development ; Central Nervous System/metabolism ; Gene Expression Regulation ; Humans ; Neurodegenerative Diseases/genetics ; Neuronal Plasticity/genetics ; Neurons/cytology ; Neurons/metabolism ; Parkinson Disease/genetics ; RNA, Long Noncoding/genetics
Chemical Substances	RNA, Long Noncoding
Language	English
Publishing date	2019-06-01
Publishing country	Singapore
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2704569-9
ISSN	2768-6698 ; 1093-9946
ISSN (online)	2768-6698
ISSN	1093-9946
DOI	10.2741/4776
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Article ; Online: Cpeb1 expression is post‐transcriptionally regulated by AUF1, CPEB1, and microRNAs

Souichi Oe / Shinichi Hayashi / Susumu Tanaka / Taro Koike / Yukie Hirahara / Rio Kakizaki / Sumika Sakamoto / Yasuko Noda / Hisao Yamada / Masaaki Kitada

FEBS Open Bio, Vol 12, Iss 1, Pp 82-

2022 Volume 94

Abstract: Cytoplasmic polyadenylation element binding protein 1 (CPEB1) regulates the translation of numerous mRNAs. We previously showed that AU‐rich binding factor 1 (AUF1) regulates Cpeb1 expression through the 3’ untranslated region (3’UTR). To investigate the ...

Abstract	Cytoplasmic polyadenylation element binding protein 1 (CPEB1) regulates the translation of numerous mRNAs. We previously showed that AU‐rich binding factor 1 (AUF1) regulates Cpeb1 expression through the 3’ untranslated region (3’UTR). To investigate the molecular basis of the regulatory potential of the Cpeb1 3’UTR, here we performed reporter analyses that examined expression levels of Gfp reporter mRNA containing the Cpeb1 3’UTR. Our findings indicate that CPEB1 represses the translation of Cpeb1 mRNA and that miR‐145a‐5p and let‐7b‐5p are involved in the reduction in Cpeb1 expression in the absence of AUF1. These results suggest that Cpeb1 expression is post‐transcriptionally regulated by AUF1, CPEB1, and microRNAs.
Keywords	CPEB1 ; AUF1 ; miR‐145a‐5p ; let‐7b‐5p ; post‐transcriptional regulation ; Neuro2a cell ; Biology (General) ; QH301-705.5
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Wiley
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Virulence of Herpes Simplex Virus 1 Harboring a UAG Stop Codon between the First and Second Initiation Codon in the Thymidine Kinase Gene.

Nguyen, Phu Hoang Anh / Yamada, Souichi / Harada, Shizuko / Fukushi, Shuetsu / Mizuguchi, Masashi / Saijo, Masayuki

Japanese journal of infectious diseases

2021 Volume 75, Issue 4, Page(s) 368–373

Abstract: Herpes simplex virus 1 (HSV-1)-TK (8UAG) expresses a truncated thymidine kinase (TK) translated from the second initiation codon due to a stop codon (UAG) at the 8th position (counted from the first initiation codon). Here, we showed that the sensitivity ...

Abstract	Herpes simplex virus 1 (HSV-1)-TK (8UAG) expresses a truncated thymidine kinase (TK) translated from the second initiation codon due to a stop codon (UAG) at the 8th position (counted from the first initiation codon). Here, we showed that the sensitivity of HSV-1-TK (8UAG) to acyclovir (ACV) is similar to that of the control HSV-1 wild-type (WT), which expresses an intact TK protein. However, HSV-1-TK (44UAG), which expresses a truncated TK due to a UAG codon at position 44, showed lower sensitivity to ACV. A mouse infection model was used to compare the virulence of HSV-1-TK (8UAG) and HSV-1-TK (44UAG) to that of HSV-1 WT. The 50% lethal dose (LD
MeSH term(s)	Acyclovir ; Animals ; Antiviral Agents/pharmacology ; Codon, Initiator/genetics ; Codon, Terminator/genetics ; Herpesvirus 1, Human/genetics ; Herpesvirus 1, Human/pathogenicity ; Mice ; Mutation ; Thymidine Kinase/genetics ; Virulence/genetics
Chemical Substances	Antiviral Agents ; Codon, Initiator ; Codon, Terminator ; Thymidine Kinase (EC 2.7.1.21) ; Acyclovir (X4HES1O11F)
Language	English
Publishing date	2021-12-28
Publishing country	Japan
Document type	Journal Article
ZDB-ID	1478383-6
ISSN	1884-2836 ; 1344-6304
ISSN (online)	1884-2836
ISSN	1344-6304
DOI	10.7883/yoken.JJID.2021.674
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Article ; Online: Performance Evaluation of Real-Time RT-PCR Assays for the Detection of Severe Acute Respiratory Syndrome Coronavirus-2 Developed by the National Institute of Infectious Diseases, Japan.

Shirato, Kazuya / Tomita, Yuriko / Katoh, Hiroshi / Yamada, Souichi / Fukushi, Shuetsu / Matsuyama, Shutoku / Takeda, Makoto

Japanese journal of infectious diseases

2021 Volume 74, Issue 5, Page(s) 465–472

Abstract: Soon after the 2019 outbreak of coronavirus disease 2019 in Wuhan, China, a protocol for real-time RT-PCR assay detection of severe acute respiratory syndrome coronavirus (SARS-CoV-2) was established by the National Institute of Infectious Diseases (NIID) ...

Abstract	Soon after the 2019 outbreak of coronavirus disease 2019 in Wuhan, China, a protocol for real-time RT-PCR assay detection of severe acute respiratory syndrome coronavirus (SARS-CoV-2) was established by the National Institute of Infectious Diseases (NIID) in Japan. The protocol used Charité's nucleocapsid (Sarbeco-N) and NIID nucleocapsid (NIID-N2) assays. During the following months, SARS-CoV-2 spread and caused a global pandemic, and various SARS-CoV-2 sequences were registered in public databases, such as the Global Initiative on Sharing All Influenza Data (GISAID). In this study, we evaluated the S2 assay (NIID-S2) that was newly developed to replace the Sarbeco-N assay and the performance of the NIID-N2 and NIID-S2 assays, referring to mismatches in the primer/probe targeted region. We found that the analytical sensitivity and specificity of the NIID-S2 set were comparable to those of the NIID-N2 assay, and the detection rate for clinical specimens was identical to that of the NIID-N2 assay. Furthermore, among the available sequences (approximately 192,000), the NIID-N2 and NIID-S2 sets had 2.6% and 1.2% mismatched sequences, respectively, although most of these mismatches did not affect the amplification efficiency, except the 3' end of the NIID-N2 forward primer. These findings indicate that the previously developed NIID-N2 assay is suitable for the detection of SARS-CoV-2 with support from the newly developed NIID-S2 set.
MeSH term(s)	COVID-19/diagnosis ; COVID-19 Nucleic Acid Testing/methods ; Coronavirus Nucleocapsid Proteins/genetics ; DNA Primers/genetics ; Humans ; Japan ; Phosphoproteins/genetics ; RNA, Viral/analysis ; RNA, Viral/genetics ; SARS-CoV-2/genetics ; SARS-CoV-2/isolation & purification ; Sensitivity and Specificity ; Spike Glycoprotein, Coronavirus/genetics
Chemical Substances	Coronavirus Nucleocapsid Proteins ; DNA Primers ; Phosphoproteins ; RNA, Viral ; Spike Glycoprotein, Coronavirus ; nucleocapsid phosphoprotein, SARS-CoV-2 ; spike protein, SARS-CoV-2
Language	English
Publishing date	2021-02-26
Publishing country	Japan
Document type	Evaluation Study ; Journal Article
ZDB-ID	1478383-6
ISSN	1884-2836 ; 1344-6304
ISSN (online)	1884-2836
ISSN	1344-6304
DOI	10.7883/yoken.JJID.2020.1079
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Article ; Online: Impact of Reinfection with SARS-CoV-2 Omicron Variants in Previously Infected Hamsters.

Shiwa-Sudo, Nozomi / Sakai, Yusuke / Iwata-Yoshikawa, Naoko / Watanabe, Shinji / Yamada, Souichi / Kuroda, Yudai / Yamamoto, Tsukasa / Shirakura, Masayuki / Fujisaki, Seiichiro / Miyazaki, Kaya / Miura, Hideka / Nagata, Shiho / Fukushi, Shuetsu / Maeda, Ken / Hasegawa, Hideki / Suzuki, Tadaki / Nagata, Noriyo

Journal of virology

2023 Volume 97, Issue 1, Page(s) e0136622

Abstract: The diversity of SARS-CoV-2 mutations raises the possibility of reinfection of individuals previously infected with earlier variants, and this risk is further increased by the emergence of the B.1.1.529 Omicron variant. In this study, we used ... ...

Abstract	The diversity of SARS-CoV-2 mutations raises the possibility of reinfection of individuals previously infected with earlier variants, and this risk is further increased by the emergence of the B.1.1.529 Omicron variant. In this study, we used an
MeSH term(s)	Animals ; Cricetinae ; COVID-19 ; Mesocricetus ; Reinfection ; RNA, Viral ; SARS-CoV-2/genetics
Chemical Substances	RNA, Viral
Language	English
Publishing date	2023-01-12
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	80174-4
ISSN	1098-5514 ; 0022-538X
ISSN (online)	1098-5514
ISSN	0022-538X
DOI	10.1128/jvi.01366-22
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Article ; Online: Pathological and virological findings of type I interferon receptor knockout mice upon experimental infection with Heartland virus.

Fujii, Hikaru / Fukushi, Shuetsu / Yoshikawa, Tomoki / Nagata, Noriyo / Taniguchi, Satoshi / Shimojima, Masayuki / Yamada, Souichi / Tani, Hideki / Uda, Akihiko / Maeki, Takahiro / Harada, Shizuko / Kurosu, Takeshi / Lim, Chang Kweng / Nakayama, Eri / Takayama-Ito, Mutsuyo / Watanabe, Shumpei / Ebihara, Hideki / Morikawa, Shigeru / Saijo, Masayuki

Virus research

2023 Volume 340, Page(s) 199301

Abstract: Heartland virus (HRTV) causes generalized symptoms, severe shock, and multiple organ failure. We previously reported that interferon-α/β receptor knockout ( ... ...

Abstract	Heartland virus (HRTV) causes generalized symptoms, severe shock, and multiple organ failure. We previously reported that interferon-α/β receptor knockout (IFNAR
MeSH term(s)	Animals ; Mice ; Receptor, Interferon alpha-beta/genetics ; Mice, Knockout ; Interferons ; Liver ; Interleukin-12 ; Interferon Type I ; Bunyaviridae
Chemical Substances	Receptor, Interferon alpha-beta (156986-95-7) ; Interferons (9008-11-1) ; Interleukin-12 (187348-17-0) ; Interferon Type I
Language	English
Publishing date	2023-12-16
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	605780-9
ISSN	1872-7492 ; 0168-1702
ISSN (online)	1872-7492
ISSN	0168-1702
DOI	10.1016/j.virusres.2023.199301
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