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  1. Article: BROMOCRIPTINE IN PARKINSON'S DISEASE : PROC. OF A SYMP. HELD AT ... DROITWICH SPA, 5TH MARCH, 1981/ED.: C. D. MARSDEN

    Marsden, Charles David

    1981  

    Title variant BROMOCRIPTINE IN PARKINSON'S DISEASE
    Keywords BROMOCRIPTINE / THERAPEUTIC USE / CONGRESSES ; PARKINSON DISEASE / DRUG THERAPY / CONGRESSES
    Document type Article
    Note IN: RESEARCH AND CLINICAL FORUMS 3,2. 1981, S. 1-53
    HBZ-ID HT002637106
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    ZS A 1497 verfügbar in Königswinter Königswinter

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  2. Book: Marsden's book of movement disorders

    Donaldson, Ivan M. / Marsden, Charles David

    2012  

    Title variant Book of movement disorders ; Movement disorders
    Author's details Ivan Donaldson
    Language English
    Size XIV, 1497 S. : Ill., graph. Darst., 28 cm
    Publisher Oxford Univ. Press
    Publishing place Oxford u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT017199326
    ISBN 978-0-19-261911-2 ; 0-19-261911-X
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2012 A 1681 order for loan Magazin

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  3. Book: Movement disorders / 4 / ed. by Anthony H. V. Schapira ...

    Schapira, Anthony H. V. / Marsden, Charles David

    (Blue books of neurology series ; 35)

    2010  

    Author's details ed. by C. David Marsden
    Series title Blue books of neurology series ; 35
    Movement disorders
    Blue books of neurology
    Collection Movement disorders
    Blue books of neurology
    Language English
    Size XXV, 684 S. : Ill., graph. Darst.
    Edition 1. ed.
    Publisher Butterworth
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book
    Note In der CIP-Aufn. fälschlicherweise als Bd. 34 bezeichnet
    HBZ-ID HT016317088
    ISBN 978-1-4160-6641-5 ; 1-4160-6641-1
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2010 A 2110 order for loan Magazin

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  4. Book ; Conference proceedings: Cabergoline

    Marsden, Charles David

    advantages of sustained dopaminergic stimulation ; proceedings of a Satellite Symposium to the XIIth International Symposium on Parkinson's Disease Entitled "Cabergoline - Advantages of Sustained Dopaminergic Stimulation", held in London, March, 1997

    (Drugs ; 55, Suppl. 1)

    1998  

    Event/congress International Symposium on Parkinson's Disease (12, 1997, London) ; Satellite Symposium Entitled Cabergoline: Advantages of Sustained Dopaminergic Stimulation (1997, London)
    Author's details guest ed.: C. D. Marsden
    Series title Drugs ; 55, Suppl. 1
    Collection
    Keywords Ergolines / therapeutic use / congresses ; Dopamine Antagonists / therapeutic use / congresses ; Parkinson Disease / drug therapy / congresses ; Delayed-Action Preparations / congresses
    Language English
    Size 30 S. : Ill., graph. Darst.
    Publisher Adis Internat
    Publishing place Auckland u.a.
    Publishing country New Zealand
    Document type Book ; Conference proceedings
    HBZ-ID HT008165473
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    Zs A 762 -55,Suppl.1- not available for loan Zeitschriften-Lesesaal

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  5. Article ; Online: Exploring current undergraduate student perspectives on the introduction of the degree apprenticeship scheme in diagnostic radiography - a single institution study.

    Green, D / Heales, C J / Hughes, D / Marsden, A / Mills, J A

    Radiography (London, England : 1995)

    2022  Volume 28, Issue 4, Page(s) 1058–1063

    Abstract: Introduction: The first degree apprenticeship programme in diagnostic radiography was launched in March 2020. This route into radiography runs in parallel with 'conventional' pre-registration programmes where students apply to a higher education ... ...

    Abstract Introduction: The first degree apprenticeship programme in diagnostic radiography was launched in March 2020. This route into radiography runs in parallel with 'conventional' pre-registration programmes where students apply to a higher education institution (HEI) and undertake discrete clinical placements. The aim of this study was to explore the perspectives of pre-registration students on the diagnostic radiographer degree apprenticeship route.
    Methods: A qualitative approach (online questionnaire) gathered attitudes and opinions of pre-registration students from a single HEI, regarding the degree apprenticeship programme. Participants were pre-registration medical imaging students from all stages of the programme (n = 204). Braun and Clarks's thematic analysis was employed for data analysis.
    Results: A response rate of 21% (n = 44) was recorded. Four themes emerged from data analysis: (1) misunderstandings surrounding the degree apprenticeship, (2) financial implications and (3) practical experience associated with both degree courses and (4) the experience the pre-registration degree has to offer.
    Conclusion: There was an apparent lack of understanding regarding the degree apprenticeship leading students to misinterpret aspects of the course. Additionally, students highlighted the earning aspect of the apprenticeship to be an advantage in comparison to student debts associated with the traditional pre-registration programmes. Furthermore, students emphasised the advantage of the clinical focus practice associated with the degree apprenticeship. Nevertheless, students who have selected the HEI route still value what the traditional pre-registration degree offers.
    Implications for practice: As degree apprenticeship programmes become widely available, a greater awareness should, therefore, follow. In the interim, there is scope for HEIs to seek to raise awareness of degree apprenticeship provision. HEIs should seek to allay any concerns and highlight the benefits of having this alternative route into the profession.
    MeSH term(s) Humans ; Radiography ; Students, Medical ; Surveys and Questionnaires ; Universities
    Language English
    Publishing date 2022-08-19
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1289102-2
    ISSN 1532-2831 ; 1078-8174
    ISSN (online) 1532-2831
    ISSN 1078-8174
    DOI 10.1016/j.radi.2022.08.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4438: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Book ; Conference proceedings: Botulinum toxin in the future

    Marsden, Charles David

    proceedings of the 3rd European Botulinum Toxin Symposium, 28 February - 2 March 1997, London, UK

    (European journal of neurology ; 4, Suppl. 2)

    1997  

    Event/congress European Botulinum Toxin Symposium (3, 1997, London)
    Author's details guest ed.: C. David Marsden
    Series title European journal of neurology ; 4, Suppl. 2
    Collection
    Keywords Botulinum Toxin Type A / therapeutic use / congresses
    Language English
    Size S91 S. : Ill., graph. Darst.
    Publisher Rapid Science
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book ; Conference proceedings
    HBZ-ID HT008165684
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    Zs A 4738 -4,Suppl.2- not available for loan Zeitschriften-Lesesaal

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  7. Book: Clinical neurology

    Marsden, Charles David / Fowler, Timothy J.

    1998  

    Author's details C. David Marsden ; Timothy J. Fowler
    Keywords Nervous System Diseases / diagnosis ; Nervous System Diseases / therapy
    Language English
    Size IX, 446 S. : Ill.
    Edition 2. ed.
    Publisher Arnold
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT008498049
    ISBN 0-340-64611-X ; 978-0-340-64611-3
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1998 A 3697 order for loan Magazin

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  8. Article ; Online: Association of delirium screening on hospitalized adults and postacute care utilization: A retrospective cohort study.

    Dulin, Jennifer D / Zhang, Jingwen / Marsden, Justin / Mauldin, Patrick D / Moran, William P / Kalivas, Benjamin C

    The American journal of the medical sciences

    2022  Volume 364, Issue 5, Page(s) 554–564

    Abstract: Background: Patients with delirium have increased hospital length of stay (LOS), morbidity and mortality. Impact of delirium on postacute care (PAC) utilization is not fully characterized. Impact of screening for delirium on general medicine patients is ...

    Abstract Background: Patients with delirium have increased hospital length of stay (LOS), morbidity and mortality. Impact of delirium on postacute care (PAC) utilization is not fully characterized. Impact of screening for delirium on general medicine patients is unknown. The objective of this study was to assess impact of screening for delirium on inpatient PAC utilization.
    Methods: This was a single center, retrospective cohort study at an academic tertiary care center in Charleston, SC. Patients were selected from adults hospitalized from home and discharged alive between June 2014 and June 2018. The brief confusion assessment method (bCAM) screening was conducted and documented by nursing on admission and every shift thereafter. Outcome measure was the proportion of patients discharged to facility.
    Results: Of 93,388 non-ICU adult admission between June 2014 and June 2018, 4.4% of those not screened for delirium were discharged to facility versus 15.0% in those screened and 41.4% in those screening positive. Multivariable regression analysis showed that patients screened for delirium were 2.3 times more likely to discharge to facility (95% CI (2.145, 2.429)) while those with a positive bCAM were 3.3 times more likely than those with a negative bCAM to discharge to facility (95% CI (2.949, 3.712)).
    Conclusions: After adjusting for demographics, medication orders and comorbidities there was an association between screening for delirium, positive delirium screen and discharge to facility. An appreciation of where and why patients are discharged is imperative to optimize both patient care and cost utilization.
    MeSH term(s) Humans ; Subacute Care ; Retrospective Studies ; Hospitalization ; Patient Discharge ; Delirium/diagnosis ; Delirium/epidemiology
    Language English
    Publishing date 2022-07-03
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 82078-7
    ISSN 1538-2990 ; 0002-9629
    ISSN (online) 1538-2990
    ISSN 0002-9629
    DOI 10.1016/j.amjms.2022.06.022
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    Ua VI Zs.2/10: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: COMBATdb: a database for the COVID-19 Multi-Omics Blood ATlas.

    Wang, Dapeng / Kumar, Vinod / Burnham, Katie L / Mentzer, Alexander J / Marsden, Brian D / Knight, Julian C

    Nucleic acids research

    2022  Volume 51, Issue D1, Page(s) D896–D905

    Abstract: Advances in our understanding of the nature of the immune response to SARS-CoV-2 infection, and how this varies within and between individuals, is important in efforts to develop targeted therapies and precision medicine approaches. Here we present a ... ...

    Abstract Advances in our understanding of the nature of the immune response to SARS-CoV-2 infection, and how this varies within and between individuals, is important in efforts to develop targeted therapies and precision medicine approaches. Here we present a database for the COvid-19 Multi-omics Blood ATlas (COMBAT) project, COMBATdb (https://db.combat.ox.ac.uk). This enables exploration of multi-modal datasets arising from profiling of patients with different severities of illness admitted to hospital in the first phase of the pandemic in the UK prior to vaccination, compared with community cases, healthy controls, and patients with all-cause sepsis and influenza. These data include whole blood transcriptomics, plasma proteomics, epigenomics, single-cell multi-omics, immune repertoire sequencing, flow and mass cytometry, and cohort metadata. COMBATdb provides access to the processed data in a well-defined framework of samples, cell types and genes/proteins that allows exploration across the assayed modalities, with functionality including browse, search, download, calculation and visualisation via shiny apps. This advances the ability of users to leverage COMBAT datasets to understand the pathogenesis of COVID-19, and the nature of specific and shared features with other infectious diseases.
    MeSH term(s) Humans ; COVID-19/epidemiology ; Multiomics ; SARS-CoV-2/genetics ; Proteomics ; Databases, Factual
    Language English
    Publishing date 2022-10-26
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 186809-3
    ISSN 1362-4962 ; 1362-4954 ; 0301-5610 ; 0305-1048
    ISSN (online) 1362-4962 ; 1362-4954
    ISSN 0301-5610 ; 0305-1048
    DOI 10.1093/nar/gkac1019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1067: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article: Accuracy of an artificial intelligence as a medical device as part of a UK-based skin cancer teledermatology service.

    Marsden, Helen / Kemos, Polychronis / Venzi, Marcello / Noy, Mariana / Maheswaran, Shameera / Francis, Nicholas / Hyde, Christopher / Mullarkey, Daniel / Kalsi, Dilraj / Thomas, Lucy

    Frontiers in medicine

    2024  Volume 11, Page(s) 1302363

    Abstract: Introduction: An artificial intelligence as a medical device (AIaMD), built on convolutional neural networks, has demonstrated high sensitivity for melanoma. To be of clinical value, it needs to safely reduce referral rates. The primary objective of ... ...

    Abstract Introduction: An artificial intelligence as a medical device (AIaMD), built on convolutional neural networks, has demonstrated high sensitivity for melanoma. To be of clinical value, it needs to safely reduce referral rates. The primary objective of this study was to demonstrate that the AIaMD had a higher rate of correctly classifying lesions that did not need to be referred for biopsy or urgent face-to-face dermatologist review, compared to teledermatology standard of care (SoC), while achieving the same sensitivity to detect malignancy. Secondary endpoints included the sensitivity, specificity, positive and negative predictive values, and number needed to biopsy to identify one case of melanoma or squamous cell carcinoma (SCC) by both the AIaMD and SoC.
    Methods: This prospective, single-centre, single-arm, masked, non-inferiority, adaptive, group sequential design trial recruited patients referred to a teledermatology cancer pathway (clinicaltrials.gov NCT04123678). Additional dermoscopic images of each suspicious lesion were taken using a smartphone with a dermoscopic lens attachment. The images were assessed independently by a consultant dermatologist and the AIaMD. The outputs were compared with the final histological or clinical diagnosis.
    Results: A total of 700 patients with 867 lesions were recruited, of which 622 participants with 789 lesions were included in the per-protocol (PP) population. In total, 63.3% of PP participants were female; 89.0% identified as white, and the median age was 51 (range 18-95); and all Fitzpatrick skin types were represented including 25/622 (4.0%) type IV-VI skin. A total of 67 malignant lesions were identified, including 8 diagnosed as melanoma. The AIaMD sensitivity was set at 91 and 92.5%, to match the literature-defined clinician sensitivity (91.46%) as closely as possible. In both settings, the AIaMD identified had a significantly higher rate of identifying lesions that did not need a biopsy or urgent referral compared to SoC (
    Discussion: The AIaMD identified significantly more lesions that did not need to be referred for biopsy or urgent face-to-face dermatologist review, compared to teledermatologists. This has the potential to reduce the burden of unnecessary referrals when used as part of a teledermatology service.
    Language English
    Publishing date 2024-03-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2024.1302363
    Database MEDical Literature Analysis and Retrieval System OnLINE

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