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  1. Article ; Online: Commentary: Aducanumab-Related ARIA: Paean or Lament?

    Wassef, Heidi R / Colletti, Patrick M

    Clinical nuclear medicine

    2022  Volume 47, Issue 8, Page(s) 707–709

    Abstract: Abstract: Høilund-Carlsen and colleagues raise important issues related to amyloid PET, diagnosis of Alzheimer disease, and recently approved antiamyloid treatment aducanumab. We discuss new developments that may direct us to methods of presymptomatic ... ...

    Abstract Abstract: Høilund-Carlsen and colleagues raise important issues related to amyloid PET, diagnosis of Alzheimer disease, and recently approved antiamyloid treatment aducanumab. We discuss new developments that may direct us to methods of presymptomatic detection of Alzheimer disease and development of effective prevention and therapy.
    MeSH term(s) Alzheimer Disease/diagnostic imaging ; Amyloid ; Amyloid beta-Peptides ; Antibodies, Monoclonal, Humanized/adverse effects ; Humans ; Plaque, Amyloid
    Chemical Substances Amyloid ; Amyloid beta-Peptides ; Antibodies, Monoclonal, Humanized ; aducanumab (105J35OE21)
    Language English
    Publishing date 2022-05-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 197628-x
    ISSN 1536-0229 ; 0363-9762
    ISSN (online) 1536-0229
    ISSN 0363-9762
    DOI 10.1097/RLU.0000000000004252
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Re: Aducanumab-Related ARIA: Paean or Lament?

    Wassef, Heidi R / Colletti, Patrick M

    Clinical nuclear medicine

    2022  Volume 48, Issue 2, Page(s) 168–169

    Abstract: Abstract: Høilund-Carlsen and colleagues raise concern regarding the reliability of amyloid PET to exclude Alzheimer disease. We present additional studies of amyloid PET and discuss the diagnostic challenges in Alzheimer disease. We discuss the ... ...

    Abstract Abstract: Høilund-Carlsen and colleagues raise concern regarding the reliability of amyloid PET to exclude Alzheimer disease. We present additional studies of amyloid PET and discuss the diagnostic challenges in Alzheimer disease. We discuss the limitations of amyloid in diagnosis and evaluation of therapy response in AD.
    MeSH term(s) Humans ; Alzheimer Disease/diagnostic imaging ; Reproducibility of Results ; Antibodies, Monoclonal, Humanized/adverse effects ; Amyloid ; Amyloid beta-Peptides
    Chemical Substances aducanumab (105J35OE21) ; Antibodies, Monoclonal, Humanized ; Amyloid ; Amyloid beta-Peptides
    Language English
    Publishing date 2022-11-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 197628-x
    ISSN 1536-0229 ; 0363-9762
    ISSN (online) 1536-0229
    ISSN 0363-9762
    DOI 10.1097/RLU.0000000000004490
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Lésions bénignes et pseudo-tumeurs en ORL : cas n° 3.

    Wassef, Michel

    Annales de pathologie

    2018  Volume 38, Issue 5, Page(s) 274–278

    Title translation ENT benign lesions and pseudo-tumors: Case No. 3.
    MeSH term(s) Adenoma/chemistry ; Adenoma/diagnosis ; Adenoma/epidemiology ; Adenoma/pathology ; Adult ; Biomarkers, Tumor ; Diagnosis, Differential ; Disease Management ; Ear Neoplasms/chemistry ; Ear Neoplasms/diagnosis ; Ear Neoplasms/epidemiology ; Ear Neoplasms/pathology ; Ear, Middle/pathology ; Female ; Humans ; Keratin-7/analysis ; Mucin-1/analysis ; Neoplasm Proteins/analysis
    Chemical Substances Biomarkers, Tumor ; Keratin-7 ; Mucin-1 ; Neoplasm Proteins
    Language French
    Publishing date 2018-08-09
    Publishing country France
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 225720-8
    ISSN 0242-6498
    ISSN 0242-6498
    DOI 10.1016/j.annpat.2018.07.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Lésions bénignes et pseudo-tumeurs en ORL : cas n° 4.

    Wassef, Michel

    Annales de pathologie

    2018  Volume 38, Issue 5, Page(s) 279–282

    Title translation ENT benign lesions and pseudo-tumors: Case No. 4.
    MeSH term(s) Aged ; Diagnosis, Differential ; Fibrosis ; Humans ; Leukemia, Lymphocytic, Chronic, B-Cell/complications ; Male ; Maxillary Sinus/diagnostic imaging ; Maxillary Sinus/pathology ; Maxillary Sinus Neoplasms/diagnosis ; Nasal Polyps/diagnosis ; Nasal Polyps/diagnostic imaging ; Nasal Polyps/pathology ; Tomography, X-Ray Computed
    Language French
    Publishing date 2018-08-17
    Publishing country France
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 225720-8
    ISSN 0242-6498
    ISSN 0242-6498
    DOI 10.1016/j.annpat.2018.07.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Nonhealing Ulcer in a Patient With Crohn Disease.

    Javdan, Bahar / Marwaha, Siddharth / Ali, Mahmoud / Wassef, Cindy

    Cutis

    2023  Volume 112, Issue 4, Page(s) E10–E12

    MeSH term(s) Humans ; Ulcer ; Crohn Disease/complications ; Crohn Disease/diagnosis ; Wound Healing
    Language English
    Publishing date 2023-11-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391840-3
    ISSN 2326-6929 ; 0011-4162 ; 0151-9522
    ISSN (online) 2326-6929
    ISSN 0011-4162 ; 0151-9522
    DOI 10.12788/cutis.0875
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Choroidal Nodules in Ocular Sarcoidosis.

    Abramowicz, Stéphane / Wassef, Michel / Touhami, Sara

    Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG

    2023  Volume 40, Issue 4, Page(s) e2023039

    Abstract: Background and aim: Ocular sarcoidosis is present in 30-60% of all sarcoidosis patients. Our purpose is to increase awareness of the various presentations of ocular sarcoidosis.: Methods: Short image-based clinical case report.: Results: We report ...

    Abstract Background and aim: Ocular sarcoidosis is present in 30-60% of all sarcoidosis patients. Our purpose is to increase awareness of the various presentations of ocular sarcoidosis.
    Methods: Short image-based clinical case report.
    Results: We report on a case of ocular sarcoidosis presenting with unilateral choroidal nodules in a middle-aged man. Sarcoid uveitis is generally bilateral and rather symmetrical. However, choroidal nodules are an exception to this rule, as they generally arise unilaterally. Choroidal nodules are highly responsive to oral corticosteroids. When left untreated, they may evolve to chorioretinal atrophy and secondary choroidal neovascularization.
    Conclusions: Knowledge of this presentation of ocular sarcoidosis can help clinicians optimize treatment outcomes for patients.
    Language English
    Publishing date 2023-12-20
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 1339192-6
    ISSN 2532-179X ; 1124-0490
    ISSN (online) 2532-179X
    ISSN 1124-0490
    DOI 10.36141/svdld.v40i4.15122
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    Zs.A 2076: Show issues Location:
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  7. Article: Dermal Hypersensitivity Reaction to Semaglutide: Two Case Reports.

    Ouellette, Samantha / Frias, Giulia / Shah, Radhika / Alamgir, Mahin / Wassef, Cindy

    Journal of drugs in dermatology : JDD

    2023  Volume 22, Issue 4, Page(s) 413–416

    Abstract: Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of antidiabetic agents that work by inducing insulin secretion and inhibiting release of glucagon in a glucose-dependent manner. They are especially promising given their long duration of ... ...

    Abstract Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of antidiabetic agents that work by inducing insulin secretion and inhibiting release of glucagon in a glucose-dependent manner. They are especially promising given their long duration of action, decreased risk of hypoglycemia, and added benefit of weight loss. Semaglutide is a GLP-1 receptor agonist that has been approved for type II diabetes and chronic weight management in obese adults. Cases of hypersensitivity reactions have been previously reported in patients taking GLP-1 receptor agonists dulaglutide and liraglutide. However, to our knowledge, there have been no reports of hypersensitivity reactions to semaglutide. Here, we present two cases of dermal hypersensitivity reactions in patients taking semaglutide for type II diabetes. In the first case, a 75-year-old woman who had been taking semaglutide for 10 months presented with an eruption on her legs, back, and chest for 3 months duration. Histology showed a subepidermal blister with eosinophils, suggestive of a drug hypersensitivity reaction. In the second case, a 74-year-old white man who had been taking semaglutide for 1 month presented with an eruption on the bilateral flanks and lower abdomen for 3 weeks duration. Histology revealed perivascular inflammatory cell infiltrate with eosinophils, also suggestive of a drug hypersensitivity reaction. Both patients began experiencing resolution of their symptoms within 1 month of discontinuing semaglutide. J Drugs Dermatol. 2023;22(4): doi:10.36849/JDD.6550 Citation: Ouellette S, Frias G, Shah R, et al. Dermal hypersensitivity reaction to semaglutide: Two case reports. J Drugs Dermatol. 2023;22(4):413-415. doi:10.36849/JDD.6550.
    MeSH term(s) Humans ; Male ; Adult ; Female ; Aged ; Diabetes Mellitus, Type 2/drug therapy ; Glucagon-Like Peptide-1 Receptor/agonists ; Hypoglycemic Agents/adverse effects ; Drug Hypersensitivity/diagnosis ; Drug Hypersensitivity/etiology ; Hypersensitivity
    Chemical Substances semaglutide (53AXN4NNHX) ; Glucagon-Like Peptide-1 Receptor ; Hypoglycemic Agents
    Language English
    Publishing date 2023-04-04
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2145090-0
    ISSN 1545-9616
    ISSN 1545-9616
    DOI 10.36849/JDD.6550
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5931: Show issues Location:
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  8. Article ; Online: Erosive pustular dermatosis of the scalp: causes and treatments.

    Karanfilian, Katrice M / Wassef, Cindy

    International journal of dermatology

    2020  Volume 60, Issue 1, Page(s) 25–32

    Abstract: Erosive pustular dermatosis of the scalp is a rare condition which primarily affects older women after local trauma and has historically been treated with topical steroids. As it is a rare entity and resembles other dermatologic conditions, it may easily ...

    Abstract Erosive pustular dermatosis of the scalp is a rare condition which primarily affects older women after local trauma and has historically been treated with topical steroids. As it is a rare entity and resembles other dermatologic conditions, it may easily be misdiagnosed. Identifying the causes and evaluating the efficacy of treatments of erosive pustular dermatosis of the scalp (EPDS) is of great importance to both avoid misdiagnosis and ensure optimal treatment of this rare condition. There are numerous causes. In addition to surgeries and physical injuries, topical and procedural treatments for actinic keratoses and androgenetic alopecia can trigger the development of lesions. There are also documented associations with several autoimmune and systemic conditions. Besides corticosteroids, topical tacrolimus and photodynamic therapy were the most commonly used treatments for EPDS. They were effective with few recurrences and adverse effects. Other successful treatment options were topical dapsone, silicone gels, calcipotriol, acitretin, and isotretinoin. Oral dapsone can be used in cases of disseminated disease. Zinc sulfate should be considered with low-serum zinc levels. While cyclosporine was effective, there were adverse effects that may limit its use. It is important for dermatologists to be aware of the wide array of potential causes of erosive pustular dermatosis and include it on their differential. Additionally, although high-potency topical steroids have been historically used as the first-line treatment, there are many other effective treatments that may avoid recurrence and skin atrophy, particularly in the elderly population.
    MeSH term(s) Acitretin/therapeutic use ; Adrenal Cortex Hormones/therapeutic use ; Aminolevulinic Acid/therapeutic use ; Anti-Infective Agents/therapeutic use ; Calcitriol/analogs & derivatives ; Calcitriol/therapeutic use ; Dapsone/therapeutic use ; Dermatologic Agents/therapeutic use ; Humans ; Immunosuppressive Agents/therapeutic use ; Isotretinoin/therapeutic use ; Keratolytic Agents/therapeutic use ; Photochemotherapy ; Scalp Dermatoses/drug therapy ; Scalp Dermatoses/etiology ; Tacrolimus/therapeutic use
    Chemical Substances Adrenal Cortex Hormones ; Anti-Infective Agents ; Dermatologic Agents ; Immunosuppressive Agents ; Keratolytic Agents ; calcipotriene (143NQ3779B) ; Aminolevulinic Acid (88755TAZ87) ; Dapsone (8W5C518302) ; Isotretinoin (EH28UP18IF) ; Calcitriol (FXC9231JVH) ; Acitretin (LCH760E9T7) ; Tacrolimus (WM0HAQ4WNM)
    Language English
    Publishing date 2020-06-09
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/ijd.14955
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  9. Article ; Online: Skeletal Fluorosis.

    Gerges, Maria M / Ngo, Victoria T / Tu, Jonathan / Colletti, Patrick M / Wassef, Heidi

    Clinical nuclear medicine

    2023  Volume 48, Issue 12, Page(s) 1127–1130

    Abstract: Abstract: A 27-year-old man with polysubstance abuse including methamphetamine, fentanyl, and 1.5 years of electronics compressed gas duster inhalation presented following an assault. Radiologic imaging performed for suspected fractures revealed ... ...

    Abstract Abstract: A 27-year-old man with polysubstance abuse including methamphetamine, fentanyl, and 1.5 years of electronics compressed gas duster inhalation presented following an assault. Radiologic imaging performed for suspected fractures revealed periosteal reaction, cortical thickening with increased bone density, and ligament and tendon ossification, which were not present on imaging obtained 3 years before presentation. A bone scan was subsequently performed revealing a metabolic superscan with cortical irregularity. Further investigation revealed skeletal fluorosis from electronics compressed gas duster inhalation. Skeletal fluorosis may be considered when these osseous findings are encountered.
    MeSH term(s) Male ; Humans ; Adult ; Tomography, X-Ray Computed ; Bone and Bones ; Fluorides
    Chemical Substances Fluorides (Q80VPU408O)
    Language English
    Publishing date 2023-10-25
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 197628-x
    ISSN 1536-0229 ; 0363-9762
    ISSN (online) 1536-0229
    ISSN 0363-9762
    DOI 10.1097/RLU.0000000000004911
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  10. Article: What's old is new: Valacyclovir for the treatment of pityriasis rosea, a retrospective case series.

    Ashforth, Gina M / Youssef, Sara / Bhagavathi, Veena / Wassef, Cindy / Miller, Jason H

    JAAD case reports

    2023  Volume 37, Page(s) 98–102

    Language English
    Publishing date 2023-05-20
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834220-3
    ISSN 2352-5126
    ISSN 2352-5126
    DOI 10.1016/j.jdcr.2023.05.015
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