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  1. Article: Environmental health risk factors and cutaneous leishmaniasis (CL): A case-control study in northeastern Iran.

    Sarmadi, Mohammad / Bagherian, Zahra / Ahmadi-Soleimani, S Mohammad / Rezaiemanesh, Mohammad Reza / Khodamoradi, Farzad / Rahimi, Sajjad / Azizi, Hakim

    Journal of vector borne diseases

    2024  Volume 60, Issue 4, Page(s) 372–381

    Abstract: Background & objectives: Cutaneous leishmaniasis (CL) is one of the main causes of vector-born diseases in younger population. To evaluate the association of environmental health factors on the odds of CL incidence, a case-control study was conducted in ...

    Abstract Background & objectives: Cutaneous leishmaniasis (CL) is one of the main causes of vector-born diseases in younger population. To evaluate the association of environmental health factors on the odds of CL incidence, a case-control study was conducted in northeastern Iran.
    Methods: This study was conducted within 2020-2021 based on individual and household data from a tertiary referral center. Cases were patients diagnosed with CL by PCR method; controls were selected among the patients' relatives, and information was obtained from a health registry system. Demographic and socioeconomic data of 1871 subjects, included age, sex, household information and environmental health factors. Multivariable models with environmental factors in various conditions and CL were separately fit by univariate and mixed multiple unconditional logistic regression.
    Results: Participants included 617 cases (mean [SD] age, 13.62[13.72] years; 58.20% male) and 1264 controls (mean [SD] age, 16.45[15.44] years; 50.40% male). Results revealed that the use of well-water sources compared to surface water is significantly associated with CL (odds ratio [OR]=0.204; 95%CI, 0.13-0.33;P<0.001). Muddy houses, ruined buildings or wastelands and stagnant water, canals and rivers near the houses were also associated with CL (OR=3.85; 95%CI, 1.66-8.89; P=.002; OR=2.47; 95%CI, 1.76-3.47; P<.001). Besides, existence of pine tree was found to be a risk factor (OR=3.25; 95%CI, 2.12-4.99; P<.001) and similarly for the use of waste collection system (OR=4.43; 95%CI, 3.32-7.51; P<.001).
    Interpretation & conclusion: Environmental factors related to houses were significantly associated with CL and may represent the modifiable risk factors of CL disease.
    MeSH term(s) Humans ; Adolescent ; Case-Control Studies ; Iran/epidemiology ; Leishmaniasis, Cutaneous/epidemiology ; Risk Factors ; Water ; Environmental Health
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2024-01-04
    Publishing country India
    Document type Journal Article
    ZDB-ID 2161218-3
    ISSN 0972-9062
    ISSN 0972-9062
    DOI 10.4103/0972-9062.374236
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: In Silico

    Sarmadi, Soroush / Rahbar, Mohammad Reza / Najafi, Hamideh / Chukwudozie, Onyeka S / Morowvat, Mohammad Hossein

    Recent patents on biotechnology

    2023  Volume 18, Issue 2, Page(s) 162–176

    Abstract: Background: Coronavirus disease 2019 (COVID-19) is a viral respiratory disease that is associated with severe damage to other human organs. It causes by a novel coronavirus, and it is spreading all over the world. To date, there is some approved vaccine ...

    Abstract Background: Coronavirus disease 2019 (COVID-19) is a viral respiratory disease that is associated with severe damage to other human organs. It causes by a novel coronavirus, and it is spreading all over the world. To date, there is some approved vaccine or therapeutic agent which could be effective against this disease. But their effectiveness against mutated strains is not studied completely. The spike glycoprotein on the surface of the coronaviruses gives the virus the ability to bind to host cell receptors and enter cells. Inhibition of attachment of these spikes can lead to virus neutralization by inhibiting viral entrance.
    Aims: In this study, we tried to use the virus entrance strategy against itself by utilizing virus receptor (ACE-2) in order to design an engineered protein consisting of a human Fc antibody fragment and a part of ACE-2, which reacts with virus RBD, and we also evaluated this interaction by computational methods and
    Methods: Various
    Results: The designed protein consisted of a total of 256 amino acids with a molecular weight of 28984.62 and 5.92 as a theoretical isoelectric point. Instability and aliphatic index and grand average of hydropathicity are 49.99, 69.57 and -0.594, respectively.
    Conclusions: In silico
    MeSH term(s) Humans ; COVID-19 ; Molecular Docking Simulation ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/metabolism ; COVID-19 Drug Treatment ; Protein Binding ; Patents as Topic
    Chemical Substances spike protein, SARS-CoV-2 ; Spike Glycoprotein, Coronavirus
    Language English
    Publishing date 2023-05-25
    Publishing country United Arab Emirates
    Document type Journal Article
    ISSN 2212-4012
    ISSN (online) 2212-4012
    DOI 10.2174/1872208317666230523105759
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Thought Believability and Anxious Feelings about COVID-19: A Case-Control Study in Northeastern Iran.

    Ghodrati Torbati, Abbas / Shirinzadeh Feizabadi, Atefeh / Askari, Mohammad Reza / Zandi, Anahita / Sarmadi, Mohammad

    Medical journal of the Islamic Republic of Iran

    2023  Volume 37, Page(s) 93

    Abstract: Background: Believability and thoughts are considered as the pillars of behaviors over time, and anxious feelings are a risk factor for mental disorders, especially during the coronavirus disease (COVID-19) pandemic. This study aimed to explore the ... ...

    Abstract Background: Believability and thoughts are considered as the pillars of behaviors over time, and anxious feelings are a risk factor for mental disorders, especially during the coronavirus disease (COVID-19) pandemic. This study aimed to explore the thought believability and anxious feelings of COVID-19 among infected and healthy families.
    Methods: In this hospital-based matched case-control study, health surveillance files of COVID-19 patients were collected from January to June 2021 and were analyzed statistically. In this study, two questionnaires of demographic characteristics and the Believability of Anxious Feelings and Thoughts (BAFT) were used. Data were analyzed using the One-way ANOVA.
    Results: Of 600 participants, 300 (50%) were PCR-confirmed and 300 (50%) were non-infected. Overall, 163 (54.33%) of infected people were male, 146 (48.67%) single, and 156 (52.00%) government employees. The results showed that the mean scores of physical anxiety (PA) and negative evaluation (NE) in the case group is significantly higher than the control group (
    Conclusion: Having high believability to the risks of COVID-19 may be a predictor of preventive behaviors in individuals. Worrying about COVID-19 can increase the perceived risk of a pandemic in societies and consequence, increase the general public health.
    Language English
    Publishing date 2023-08-29
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 1095990-7
    ISSN 1016-1430
    ISSN 1016-1430
    DOI 10.47176/mjiri.37.93
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: A Rare Case of Peripheral Pulmonary Artery Aneurysm and Cavitating Pneumonia in a Patient with COVID-19 Managed with an Endovascular Method.

    Rokni, Hadi / Nourizadeh, Amir Mohammad / Sarmadi, Bahareh / Rouhezamin, Mohammad Reza

    Radiology case reports

    2022  Volume 17, Issue 10, Page(s) 3694–3698

    Abstract: Peripheral pulmonary artery aneurysm (PAA), being a rare condition, is considered extremely rare following coronavirus disease 2019 (COVID-19). We present a 58-year-old male who presented with fever, malaise, and dry cough. SARS-CoV-RNA transcription- ... ...

    Abstract Peripheral pulmonary artery aneurysm (PAA), being a rare condition, is considered extremely rare following coronavirus disease 2019 (COVID-19). We present a 58-year-old male who presented with fever, malaise, and dry cough. SARS-CoV-RNA transcription-mediated amplification test was positive for the patient. After 2 days, he developed hemoptysis and back pain, and a CT scan revealed a pulmonary aneurysm, evidence of alveolar hemorrhage, and Necrotizing pneumonia. He was scheduled for pulmonary artery angiography. The angiography confirmed a fusiform aneurysm and partial coiling of the aneurysmal sac, and indoor and backdoor embolization was performed. In the follow-up, a CT scan showed complete thrombosis of the aneurysmal sac, and the patient was free of symptoms. Peripheral PAAs can show a variety of symptoms. They can even be asymptomatic. The infectious pathologies of this condition are less common than the other. COVID-19 is an extremely rare pathology. To the best of our knowledge, this is the first case of necrotizing pneumonia and peripheral PPA in an adult. Moreover, it was followed by COVID-19. A vital takeaway note for physicians is to consider PAAs as a complication when treating COVID-19 patients who don't show signs of improvement or even show signs of exacerbation.
    Language English
    Publishing date 2022-08-01
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2406300-9
    ISSN 1930-0433
    ISSN 1930-0433
    DOI 10.1016/j.radcr.2022.06.087
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: COVID-19, body mass index and cholesterol: an ecological study using global data.

    Sarmadi, Mohammad / Ahmadi-Soleimani, S Mohammad / Fararouei, Mohammad / Dianatinasab, Mostafa

    BMC public health

    2021  Volume 21, Issue 1, Page(s) 1712

    Abstract: Background: Coronavirus disease 2019 (COVID-19) is now globally considered a serious economic, social and health threat. A wide range of health related factors including Body Mass Index (BMI) is reported to be associated with the disease. In the present ...

    Abstract Background: Coronavirus disease 2019 (COVID-19) is now globally considered a serious economic, social and health threat. A wide range of health related factors including Body Mass Index (BMI) is reported to be associated with the disease. In the present study, we analyzed global databases to assess the correlation of BMI and cholesterol with the risk of COVID-19.
    Methods: In this ecological study, we used age-standardized BMI and cholesterol levels as well as the incidence and mortality ratio of COVID-19 at the national-levels obtained from the publicly available databases such as the World Health Organization (WHO) and NCD Risk Factor Collaboration (NCD-RisC). Bivariate correlation analysis was applied to assess the correlations between the study variables. Mean differences (standard deviation: SD) of BMI and cholesterol levels of different groups were tested using independent sample t-test or Mann-Whitney rank test as appropriate. Multivariable linear regression analysis was performed to identify variables affecting the incidence and mortality ratio of COVID-19.
    Results: Incidence and mortality ratio of COVID-19 were significantly higher in developed (29,639.85 ± 20,210.79 for cases and 503.24 ± 414.65 for deaths) rather than developing (8153.76 ± 11,626.36 for cases and 169.95 ± 265.78 for deaths) countries (P < 0.01). Results indicated that the correlations of BMI and cholesterol level with COVID-19 are stronger in countries with younger population. In general, the BMI and cholesterol level were positively correlated with COVID-19 incidence ratio (β = 2396.81 and β = 30,932.80, p < 0.01,‌ respectively) and mortality ratio (β = 38.18 and β = 417.52, p < 0.05,‌ respectively) after adjusting for socioeconomic and demographic factors.
    Conclusion: Countries with higher BMI or cholesterol at aggregate levels had a higher ratios of COVID-19 incidence and mortality. The aggregated level of cholesterol and BMI are important risk factors for COVID-19 major outcomes, especially in developing countries with younger populations. We recommend monitoring and promotion of health indicices to better prevent morbidity and mortality of COVID-19.
    MeSH term(s) Body Mass Index ; COVID-19 ; Cholesterol ; Humans ; Risk Factors ; SARS-CoV-2
    Chemical Substances Cholesterol (97C5T2UQ7J)
    Language English
    Publishing date 2021-09-21
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1471-2458
    ISSN (online) 1471-2458
    DOI 10.1186/s12889-021-11715-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Towards engineering mitigation of leaching of Cd and Pb in co-contaminated soils using metal oxide-based aerogel composites and biochar.

    Sanaei, Daryoush / Sarmadi, Mohammad / Dehghani, Mohammad H / Sharifan, Hamidreza / Ribeiro, Paula G / Guilherme, Luiz R G / Rahimi, Sajjad

    Environmental science. Processes & impacts

    2023  Volume 25, Issue 12, Page(s) 2110–2124

    Abstract: Applications of metal-based nanomaterials for the remediation of heavy metal (HM) contaminated environments are of great importance. The ability of metal oxide-based carbon aerogel composite to immobilize HMs in multi-metal contaminated soils has not yet ...

    Abstract Applications of metal-based nanomaterials for the remediation of heavy metal (HM) contaminated environments are of great importance. The ability of metal oxide-based carbon aerogel composite to immobilize HMs in multi-metal contaminated soils has not yet been investigated, particularly under acidic conditions. Herein, we investigate the performance of metal oxides (Sr
    MeSH term(s) Cadmium/analysis ; Lead ; Soil Pollutants/analysis ; Metals, Heavy/analysis ; Charcoal ; Carbon ; Oxides ; Soil
    Chemical Substances biochar ; Cadmium (00BH33GNGH) ; Lead (2P299V784P) ; Soil Pollutants ; Metals, Heavy ; Charcoal (16291-96-6) ; Carbon (7440-44-0) ; Oxides ; Soil
    Language English
    Publishing date 2023-12-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2703814-2
    ISSN 2050-7895 ; 2050-7887
    ISSN (online) 2050-7895
    ISSN 2050-7887
    DOI 10.1039/d3em00284e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Association between water and sanitation, air and emission pollution and climate change and neurological disease distribution: A study based on GBD data.

    Sarmadi, Mohammad / Rahimi, Sajjad / Rezaiemanesh, Mohammad Reza / Yektay, Sama

    Chemosphere

    2021  Volume 285, Page(s) 131522

    Abstract: Along with the urbanization and industrialization of countries, the prevalence of chronic diseases has increased. There is ample evidence that ambient pollution can play a major role in these diseases. This study aimed to investigate the association ... ...

    Abstract Along with the urbanization and industrialization of countries, the prevalence of chronic diseases has increased. There is ample evidence that ambient pollution can play a major role in these diseases. This study aimed to investigate the association between neurological disorders (NDs) and their subtypes with environmental factors. In this country-level study, we used the age-standardized prevalence and incidence rate (per 100,000 populations) of NDs and its subtypes that have been taken from the Global Burden of Disease (GBD) database in 2019. We used correlation and regression analysis to assess the association between variables. Also, multivariable regression analysis was performed to identify the most important variables in NDs distribution. Age-adjusted NDs incidence rate was significantly higher in developed countries compared to developing countries (11345.25 (95% CI: 11634.88-11055.62) and 9956.37 (95% CI: 10138.66-9774.08)). Association results indicated that the impact of water and sanitation could be more effective than air pollution on NDs. The increase in water and sanitation index levels was positively correlated with NDs incidence rate and prevalence (regression coefficient (b) = 38.011 (SE = 6.50) and b = 118.84 (SE = 20.64), p < 0.001, respectively) after adjusting socio-economic and demographic factors. Furthermore, the incidence of NDs was negatively correlated with the increase in air quality (b = -16.30 (SE = 7.25), p = 0.008). Water and sanitation and their related factors are plausible factors in the distribution of NDs, which may be linked to the potential role of air and water pollution, such as heavy metals and particle matters. These results can be used by politicians and municipal service planners for future planning.
    MeSH term(s) Air Pollution/adverse effects ; Air Pollution/analysis ; Climate Change ; Global Burden of Disease ; Humans ; Nervous System Diseases ; Sanitation ; Water
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2021-07-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2021.131522
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: COVID-19, body mass index and cholesterol

    Mohammad Sarmadi / S. Mohammad Ahmadi-Soleimani / Mohammad Fararouei / Mostafa Dianatinasab

    BMC Public Health, Vol 21, Iss 1, Pp 1-

    an ecological study using global data

    2021  Volume 14

    Abstract: Abstract Background Coronavirus disease 2019 (COVID-19) is now globally considered a serious economic, social and health threat. A wide range of health related factors including Body Mass Index (BMI) is reported to be associated with the disease. In the ... ...

    Abstract Abstract Background Coronavirus disease 2019 (COVID-19) is now globally considered a serious economic, social and health threat. A wide range of health related factors including Body Mass Index (BMI) is reported to be associated with the disease. In the present study, we analyzed global databases to assess the correlation of BMI and cholesterol with the risk of COVID-19. Methods In this ecological study, we used age-standardized BMI and cholesterol levels as well as the incidence and mortality ratio of COVID-19 at the national-levels obtained from the publicly available databases such as the World Health Organization (WHO) and NCD Risk Factor Collaboration (NCD-RisC). Bivariate correlation analysis was applied to assess the correlations between the study variables. Mean differences (standard deviation: SD) of BMI and cholesterol levels of different groups were tested using independent sample t-test or Mann–Whitney rank test as appropriate. Multivariable linear regression analysis was performed to identify variables affecting the incidence and mortality ratio of COVID-19. Results Incidence and mortality ratio of COVID-19 were significantly higher in developed (29,639.85 ± 20,210.79 for cases and 503.24 ± 414.65 for deaths) rather than developing (8153.76 ± 11,626.36 for cases and 169.95 ± 265.78 for deaths) countries (P < 0.01). Results indicated that the correlations of BMI and cholesterol level with COVID-19 are stronger in countries with younger population. In general, the BMI and cholesterol level were positively correlated with COVID-19 incidence ratio (β = 2396.81 and β = 30,932.80, p < 0.01,‌ respectively) and mortality ratio (β = 38.18 and β = 417.52, p < 0.05,‌ respectively) after adjusting for socioeconomic and demographic factors. Conclusion Countries with higher BMI or cholesterol at aggregate levels had a higher ratios of COVID-19 incidence and mortality. The aggregated level of cholesterol and BMI are important risk factors for COVID-19 major outcomes, especially in developing countries ...
    Keywords COVID-19 ; mortality ; BMI ; Obesity ; Cholesterol ; Risk factors ; Public aspects of medicine ; RA1-1270
    Subject code 310
    Language English
    Publishing date 2021-09-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Association of COVID-19 global distribution and environmental and demographic factors: An updated three-month study.

    Sarmadi, Mohammad / Marufi, Nilufar / Kazemi Moghaddam, Vahid

    Environmental research

    2020  Volume 188, Page(s) 109748

    Abstract: We investigated the association of some environmental and economic factors and the global distribution indicators of the COVID-19 pandemic. Since the number of cases and deaths is higher in high-income countries located in higher latitudes and colder ... ...

    Abstract We investigated the association of some environmental and economic factors and the global distribution indicators of the COVID-19 pandemic. Since the number of cases and deaths is higher in high-income countries located in higher latitudes and colder climates, further studies are required to shed light on this matter.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-29
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2020.109748
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Management of iatrogenic chloroform mucosal burn in the palate: a case report.

    Taghavi Zenouz, Ali / Katebi, Katayoun / Ghavimi, Mohammad Ali / Javadzadeh, Farshad / Hosseinpour Sarmadi, Maryam

    Journal of advanced periodontology & implant dentistry

    2022  Volume 14, Issue 1, Page(s) 46–49

    Abstract: Chloroform is used widely in endodontic treatments for solving gutta-percha points, but it can have destructive effects if it comes in to contact with oral mucosa. This article presents a case of necrotic ulcer of palatal and buccal mucosa due to ... ...

    Abstract Chloroform is used widely in endodontic treatments for solving gutta-percha points, but it can have destructive effects if it comes in to contact with oral mucosa. This article presents a case of necrotic ulcer of palatal and buccal mucosa due to injudicious use of chloroform in endodontic treatment, which has caused severe destruction in maxilla. A conservative treatment method of repeated curettage and irrigation was used and although the lesion healed completely, it had major effects on the patient's quality of life including loss of two teeth. It is important that dentist be aware of the devastating effects of imprudent application of various chemicals used in dentistry. The conservative treatment used for this case can be helpful option for similar cases.
    Language English
    Publishing date 2022-04-10
    Publishing country Iran
    Document type Case Reports
    ISSN 2645-5390
    ISSN (online) 2645-5390
    DOI 10.34172/japid.2022.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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