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Article ; Online: Safety and Efficacy of Ahmed Valve on Intractable Glaucoma in Saudi Population.

Osman, Essam A / Alkheraiji, Norah F / Abouammoh, Mohammad A / Mousa, Ahmed / Al-Obeidan, Saleh

Middle East African journal of ophthalmology

2020 Volume 27, Issue 1, Page(s) 40–46

Abstract: Purpose: The study aims to assess the efficacy and safety of Ahmed glaucoma valve implant in eyes ... of 83 patients (117 eyes) with intractable glaucoma who underwent silicone Ahmed glaucoma valve implant ... Ahmed glaucoma valve implant was safe and effective in treating cases of intractable glaucoma. ...

Abstract	Purpose: The study aims to assess the efficacy and safety of Ahmed glaucoma valve implant in eyes with intractable glaucoma and to evaluate the risk factors for failure. Methods: A retrospective evaluation of 83 patients (117 eyes) with intractable glaucoma who underwent silicone Ahmed glaucoma valve implant was done in a tertiary care center in Riyadh, Saudi Arabia, between January 2014 and December 2016. Complete success was defined as intraocular pressure (IOP) ≤21 mmHg without medication after a minimum follow-up of 6 months. Results: Eighty-three patients (117 eyes) with intractable glaucoma were evaluated. After a mean follow-up duration of 20.8 ± 3.1 (12-24) months, the overall success rate was achieved in 104 eyes (88.9%). Thirty-six eyes (30.8%) had a complete success rate, whereas 68 eyes (58.1%) had a qualified success rate. Thirteen eyes (11.1%) failed to achieve controlled IOP. The postoperative probability to fail was found to be increasing with time from 0.9% (0.9) in the 1 Conclusions: Ahmed glaucoma valve implant was safe and effective in treating cases of intractable glaucoma.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Equipment Safety ; Female ; Follow-Up Studies ; Glaucoma/physiopathology ; Glaucoma/surgery ; Glaucoma Drainage Implants ; Humans ; Infant ; Intraocular Pressure/physiology ; Male ; Middle Aged ; Postoperative Period ; Retrospective Studies ; Risk Factors ; Saudi Arabia ; Tonometry, Ocular ; Treatment Outcome ; Visual Acuity/physiology
Language	English
Publishing date	2020-04-29
Publishing country	India
Document type	Journal Article
ZDB-ID	2545467-5
ISSN	0975-1599 ; 0974-9233
ISSN (online)	0975-1599
ISSN	0974-9233
DOI	10.4103/meajo.MEAJO_249_19
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Baerveldt Glaucoma Implant versus Ahmed Glaucoma Implant in a One-Year Follow Up, Comparative Study.

Elbaklish, Khaled Hamdi / Saleh, Safaa Mohammed / Gomaa, Wael Adel

Clinical ophthalmology (Auckland, N.Z.)

2020 Volume 14, Page(s) 29–39

Abstract: Aim: To compare clinical outcomes between Ahmed glaucoma implant (AGV-S2 and FP7 models) and ... Both the Ahmed valve implant and the Baerveldt implant are effective in reducing preoperative IOP and glaucoma ...

Abstract	Aim: To compare clinical outcomes between Ahmed glaucoma implant (AGV-S2 and FP7 models) and Baerveldt-350 glaucoma implant (BGI). Design: Prospective randomized study. Methods and subjects: Eighty-one participants with glaucoma after ocular surgery or secondary glaucoma with persistent and uncontrolled IOP > 21 mmHg were randomized for placement of BGI or AGV models using a standardized surgical technique. The primary outcome was failure, which was defined as IOP >16 mmHg with glaucoma medication, on 2 consecutive study visits. Secondary outcomes were IOP, medication use, visual acuity, complications, and interventions. Results: At one-year follow up, the mean IOP was 14.76±2.5 mmHg in BGI group and 16.57±3.35 mmHg in AGV group (P=0.015). The mean number of glaucoma medications in use was 1.6±0.81 in the BGI group and 3.91±0. 0.28 in the AGV group (P <0.001). There was 1.81 mmHg difference in the mean IOP between participants in both groups with 0.85 SD difference. At 12 months, the failure rate was 11/56 (19.67%) in AGV group and 3/25 (12%) in BGI group (P=0.352). The VA was stable in 77% in the BGI group (P=0.93) versus 80% of patients in AGV group (P=0.88). No significant change was observed in logMAR Snellen VA between both groups (P=0.254). None of the patients lost light perception. Conclusion: Both the Ahmed valve implant and the Baerveldt implant are effective in reducing preoperative IOP and glaucoma medications in patients with refractory glaucoma. This trial cannot give clear clinical proof for valve superiority over the other. The Baerveldt-350 implant can be a good choice for refractory glaucoma cases. Capsular scarring around the plate is considered as the main factor for surgical failure and resistant IOP. Trial registration: The trial was registered with the Research Ethical Committee, Ain Shams University, FWA 000017585 FMASU 21/2017, and registered at Clinical Trial. gov: NCT04215575.
Language	English
Publishing date	2020-01-08
Publishing country	New Zealand
Document type	Journal Article
ISSN	1177-5467
ISSN	1177-5467
DOI	10.2147/OPTH.S224654
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Book ; Online: Photocatalysts

Awwad, Nasser S / Saeed Alarfaji, Saleh / Alomary, Ahmed

New Perspectives

2023

Keywords	Materials science ; photocatalysis ; water splitting ; semiconductors ; nanotechnology ; nanocomposite ; tio2
Language	English
Size	1 electronic resource (250 pages)
Publisher	IntechOpen
Document type	Book ; Online
Note	English
HBZ-ID	HT030380847
ISBN	9781839689826 ; 183968982X
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: Efficacy and safety of local fibrinolytic therapy in intracranial hemorrhages: A systematic review and meta-analysis of randomised controlled trials.

Rajeswaran, Arun Babu / Ali, Arshad / Safi, Saleh / Abdulghani Saleh, Ahmed Eid

World neurosurgery: X

2024 Volume 22, Page(s) 100316

Language	English
Publishing date	2024-02-27
Publishing country	United States
Document type	Journal Article ; Review
ISSN	2590-1397
ISSN (online)	2590-1397
DOI	10.1016/j.wnsx.2024.100316
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Article ; Online: Potential protective effect of catechin on doxorubicin-induced cardiotoxicity in adult male albino rats.

Saleh Ahmed, Aml Salem

Toxicology mechanisms and methods

2021 Volume 32, Issue 2, Page(s) 97–105

Abstract: Doxorubicin (DOX) is the most effective and frequently used anticancer drug but its cardiotoxicity is the most important side effect that limits the clinical use of it. This study was designed to investigate the protective role of catechin (CAT) on DOX ... ...

Abstract	Doxorubicin (DOX) is the most effective and frequently used anticancer drug but its cardiotoxicity is the most important side effect that limits the clinical use of it. This study was designed to investigate the protective role of catechin (CAT) on DOX induced cardiotoxicity. Rats were randomly divided into three groups. Group (I) served as the control. Group (II) served as toxic group, (1.66 mg/kg; i.p.). Group (III) served as protective group, was pretreated with (400 mg CAT/kg; p.o.) for 2 weeks then received DOX with CAT for 12 days. In the present study, administration of DOX induced significant (
MeSH term(s)	Animals ; Antioxidants/metabolism ; Antioxidants/pharmacology ; Cardiotoxicity/prevention & control ; Catechin/pharmacology ; Doxorubicin/toxicity ; Hydrogen Peroxide/metabolism ; Male ; Myocardium/metabolism ; Oxidative Stress ; Rats
Chemical Substances	Antioxidants ; Doxorubicin (80168379AG) ; Catechin (8R1V1STN48) ; Hydrogen Peroxide (BBX060AN9V)
Language	English
Publishing date	2021-09-29
Publishing country	England
Document type	Journal Article
ZDB-ID	2081252-8
ISSN	1537-6524 ; 1537-6516 ; 1051-7235
ISSN (online)	1537-6524
ISSN	1537-6516 ; 1051-7235
DOI	10.1080/15376516.2021.1972375
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Zs.A 3215: Show issues

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Article ; Online: Development of collagen-chitosan dressing gel functionalized with propolis-zinc oxide nanoarchitectonics to accelerate wound healing.

Zayed, Heba S / Saleh, Safaa / Omar, Areg E / Saleh, Ahmed K / Salama, Ahmed / Tolba, Emad

International journal of biological macromolecules

2024 Volume 261, Issue Pt 2, Page(s) 129665

Abstract: Using an in situ sol-gel technique, new nanoarchitectonics of propolis loaded zinc oxide nanoarchitectonics (PP/ZnO-NPs) were developed in order to improve the in vivo outcomes of collagen-chitosan gel in wounded rats. The obtained nanoarchitectonics ... ...

Abstract	Using an in situ sol-gel technique, new nanoarchitectonics of propolis loaded zinc oxide nanoarchitectonics (PP/ZnO-NPs) were developed in order to improve the in vivo outcomes of collagen-chitosan gel in wounded rats. The obtained nanoarchitectonics were fully characterized. The XRD results indicate the presence of a Zincite phase for ZnO-NPs and Zincite accompanied by a minor amount of zinc hydroxide for PP/ZnO-NPs samples. While the TEM findings illustrate the transfer of the ZnO-NPs from agglomerated spheres with an average particle size of 230 ± 29 nm to needle-like NPs of 323 ± 173 nm length (PP1/ZnO-NPs) and to a sheet-like NPs of 500 ± 173 nm diameter (PP2/ZnO-NPs). In addition, the incorporation of PP results in an increase in the surface negativity of ZnO-NPs to -31.4 ± 6.4 mV for PP2/ZnO-NPs. The antimicrobial activities of the nanocomposite gel loaded with 10%PP1/ZnO-NPs (G6) revealed the highest inhibition zone against E. coli (26 ± 2.31 mm). Remarkably, the in vivo outcomes showed that the nanocomposite gel (G6) has exceptional collagen deposition, quick wound closure rates, and re-epithelization. The outcomes demonstrate the nanocomposite gel encouraging biological properties for the treatment of damaged and infected wounds.
MeSH term(s)	Rats ; Animals ; Zinc Oxide ; Anti-Bacterial Agents/therapeutic use ; Propolis/pharmacology ; Chitosan ; Nanogels ; Escherichia coli ; Wound Healing ; Collagen ; Bandages
Chemical Substances	Zinc Oxide (SOI2LOH54Z) ; Anti-Bacterial Agents ; Propolis (9009-62-5) ; Chitosan (9012-76-4) ; Nanogels ; Collagen (9007-34-5)
Language	English
Publishing date	2024-01-23
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2024.129665
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Article ; Online: Superior survivorship and plate-related results of TomoFix compared to Puddu plate fixation for opening-wedge high tibial osteotomy: A systematic review of the literature.

Ahmed, Ahmed M / Addosooki, Ahmad / Saleh Sleem, Ahmed / Said, Elsayed

The Knee

2023 Volume 42, Page(s) 1–18

Abstract: Purpose: This systematic review aimed to compare survivorship and plate-related results of Puddu and TomoFix plates in opening-wedge high tibial osteotomy (OWHTO).: Methods: PubMed, Scopus, EMBASE, and CENTRAL databases were searched from January ... ...

Abstract	Purpose: This systematic review aimed to compare survivorship and plate-related results of Puddu and TomoFix plates in opening-wedge high tibial osteotomy (OWHTO). Methods: PubMed, Scopus, EMBASE, and CENTRAL databases were searched from January 2000 until September 2021 for clinical studies involving patients with medial compartment knee disease and varus deformity undergoing OWHTO using the Puddu or TomoFix plating systems. We extracted survival data, plate-related complications, and functional and radiological outcomes. The risk of bias assessment had been carried out using Cochrane Collaboration's quality assessment tool for randomised controlled trials (RCTs) and Methodological Index for Non-Randomised Studies (MINORS). Results: Twenty-eight studies were included. The total number of knees was 2568 in 2372 patients. The Puddu plate was used in 677 knees, while the TomoFix plate was used in 1891. The follow-up ranged from 5.8 to 147.6 months. Both plating systems were able to delay conversion to arthroplasty at different follow-up intervals. However, osteotomies fixed by the TomoFix plate achieved higher survival rates, especially at mid-term and long-term follow-ups. In addition, fewer complications were reported with the TomoFix plating system. Although both implants achieved satisfactory functional outcomes, high scores could not be maintained throughout long-term intervals. Regarding radiological results, TomoFix plate was able to achieve and maintain larger degrees of varus deformity, while preserving the posterior tibial slope. Conclusions: This systematic review demonstrated the superiority of the TomoFix over the Puddu system as a safer and more effective fixation device in OWHTO. Nevertheless, these results should be interpreted with caution due to the lack of comparative evidence through high-quality RCTs.
MeSH term(s)	Humans ; Survivorship ; Knee Joint/diagnostic imaging ; Knee Joint/surgery ; Osteotomy/methods ; Knee ; Osteoarthritis, Knee/surgery ; Osteoarthritis, Knee/complications ; Bone Plates ; Tibia/surgery
Language	English
Publishing date	2023-03-01
Publishing country	Netherlands
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	1200476-5
ISSN	1873-5800 ; 0968-0160
ISSN (online)	1873-5800
ISSN	0968-0160
DOI	10.1016/j.knee.2023.02.010
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Zs.A 4043: Show issues

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Article ; Conference proceedings: Factors affecting length of hospital stay in penetrating neck trauma patients

Saleh, Mohamed Ahmed Ezzat

Laryngo-Rhino-Otologie

2023 Volume 102, Issue S 02

Event/congress	94th Annual Meeting German Society of Oto-Rhino-Laryngology, Head and Neck Surgery e.V., Bonn, Congress Center Leipzig, 2023-05-17
Language	English
Publishing date	2023-05-01
Publisher	Georg Thieme Verlag
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	96005-6
ISSN	1438-8685 ; 0935-8943 ; 0340-1588
ISSN (online)	1438-8685
ISSN	0935-8943 ; 0340-1588
DOI	10.1055/s-0043-1767120
Database	Thieme publisher's database

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Article: Plasminogen activator urokinase receptor as a diagnostic and prognostic biomarker in type 2 diabetic patients with cardiovascular disease.

Mohammed, Melak Saleh / Ahmed, Hind Shakir

Journal of cardiovascular and thoracic research

2023 Volume 15, Issue 3, Page(s) 154–160

Abstract: Introduction: Cardiovascular diseases are the main cause of death among type 2 diabetic patients. Higher levels of plasminogen activator urokinase receptor have been found to predict morbidity and mortality across acute and chronic diseases in the ... ...

Abstract	Introduction: Cardiovascular diseases are the main cause of death among type 2 diabetic patients. Higher levels of plasminogen activator urokinase receptor have been found to predict morbidity and mortality across acute and chronic diseases in the common populace. This study aims to explore the role of serum plasminogen activator urokinase receptor levels as a cardiometabolic risk factor among type 2 diabetic Iraqi patients. Methods: Seventy type 2 diabetic patients (40 male and 30 female) (mean age: 46.20±7.56 years) participated in this study; 35 patients were with cardiovascular disease and 35 were without cardiovascular disease; their ages range was 40-55 years. In addition, 30 individuals who apparently healthy were selected as the control group. Results: There were significant increases ( Conclusion: It has been concluded that serum plasminogen activator urokinase receptor showed higher levels among type 2 diabetic patients with cardiovascular disease, this revealed it's critical role in cardiac disease. Therefore, it could be considered a more sensitive biomarker for the detection of cardiovascular events among type 2 diabetic patients who were at high-risk.
Language	English
Publishing date	2023-09-23
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2654729-6
ISSN	2008-6830 ; 2008-5117
ISSN (online)	2008-6830
ISSN	2008-5117
DOI	10.34172/jcvtr.2023.32895
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Article ; Online: Diseases diagnosis based on artificial intelligence and ensemble classification.

Rabie, Asmaa H / Saleh, Ahmed I

Artificial intelligence in medicine

2023 Volume 148, Page(s) 102753

Abstract: Background: In recent years, Computer Aided Diagnosis (CAD) has become an important research area that attracted a lot of researchers. In medical diagnostic systems, several attempts have been made to build and enhance CAD applications to avoid errors ... ...

Abstract	Background: In recent years, Computer Aided Diagnosis (CAD) has become an important research area that attracted a lot of researchers. In medical diagnostic systems, several attempts have been made to build and enhance CAD applications to avoid errors that can cause dangerously misleading medical treatments. The most exciting opportunity for promoting the performance of CAD system can be accomplished by integrating Artificial Intelligence (AI) in medicine. This allows the effective automation of traditional manual workflow, which is slow, inaccurate and affected by human errors. Aims: This paper aims to provide a complete Computer Aided Disease Diagnosis (CAD Methods: The proposed CAD Results: The proposed CAD Conclusion: It is concluded that CAD
MeSH term(s)	Humans ; Artificial Intelligence ; Diagnosis, Computer-Assisted/methods ; Machine Learning
Language	English
Publishing date	2023-12-29
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	645179-2
ISSN	1873-2860 ; 0933-3657
ISSN (online)	1873-2860
ISSN	0933-3657
DOI	10.1016/j.artmed.2023.102753
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