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Article ; Online: Unveiling the reasons for disparities in prevalence of asthma and allergic conditions in Black children: The role of socioeconomic status.

Federman, Alex / Wisnivesky, Juan P

The Journal of allergy and clinical immunology

2024 Volume 153, Issue 4, Page(s) 983–984

MeSH term(s)	Child ; Humans ; Prevalence ; Asthma/epidemiology ; Dermatitis, Atopic/epidemiology ; Social Class
Language	English
Publishing date	2024-02-03
Publishing country	United States
Document type	Editorial
ZDB-ID	121011-7
ISSN	1097-6825 ; 1085-8725 ; 0091-6749
ISSN (online)	1097-6825 ; 1085-8725
ISSN	0091-6749
DOI	10.1016/j.jaci.2024.01.020
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Article ; Online: Lung Cancer Disparities Outcomes: The Urgent Need for Narrowing Care Gaps.

Wisnivesky, Juan P / Smith, Cardinale B

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

2022 Volume 40, Issue 16, Page(s) 1718–1720

MeSH term(s)	Healthcare Disparities ; Humans ; Lung Neoplasms/therapy
Language	English
Publishing date	2022-04-15
Publishing country	United States
Document type	Editorial ; Research Support, Non-U.S. Gov't ; Comment
ZDB-ID	604914-x
ISSN	1527-7755 ; 0732-183X
ISSN (online)	1527-7755
ISSN	0732-183X
DOI	10.1200/JCO.22.00321
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Zs.A 1847: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: The global burden of lung cancer: current status and future trends.

Leiter, Amanda / Veluswamy, Rajwanth R / Wisnivesky, Juan P

Nature reviews. Clinical oncology

2023 Volume 20, Issue 9, Page(s) 624–639

Abstract: Lung cancer is the leading cause of cancer-related death worldwide. However, lung cancer incidence and mortality rates differ substantially across the world, reflecting varying patterns of tobacco smoking, exposure to environmental risk factors and ... ...

Abstract	Lung cancer is the leading cause of cancer-related death worldwide. However, lung cancer incidence and mortality rates differ substantially across the world, reflecting varying patterns of tobacco smoking, exposure to environmental risk factors and genetics. Tobacco smoking is the leading risk factor for lung cancer. Lung cancer incidence largely reflects trends in smoking patterns, which generally vary by sex and economic development. For this reason, tobacco control campaigns are a central part of global strategies designed to reduce lung cancer mortality. Environmental and occupational lung cancer risk factors, such as unprocessed biomass fuels, asbestos, arsenic and radon, can also contribute to lung cancer incidence in certain parts of the world. Over the past decade, large-cohort clinical studies have established that low-dose CT screening reduces lung cancer mortality, largely owing to increased diagnosis and treatment at earlier disease stages. These data have led to recommendations that individuals with a high risk of lung cancer undergo screening in several economically developed countries and increased implementation of screening worldwide. In this Review, we provide an overview of the global epidemiology of lung cancer. Lung cancer risk factors and global risk reduction efforts are also discussed. Finally, we summarize lung cancer screening policies and their implementation worldwide.
MeSH term(s)	Humans ; Lung Neoplasms/epidemiology ; Early Detection of Cancer ; Risk Factors ; Tobacco Control
Language	English
Publishing date	2023-07-21
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2491410-1
ISSN	1759-4782 ; 1759-4774
ISSN (online)	1759-4782
ISSN	1759-4774
DOI	10.1038/s41571-023-00798-3
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Zs.A 6029: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MG 103: Show issues

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Article ; Online: Lung Cancer Screening in Patients With Chronic Obstructive Pulmonary Disease: Do the Benefits Outweigh the Risks?

de-Torres, Juan P / Wisnivesky, Juan P

Archivos de bronconeumologia

2021

Language	Spanish
Publishing date	2021-04-26
Publishing country	Spain
Document type	Editorial
ZDB-ID	2591346-3
ISSN	2173-5751 ; 2173-5751
ISSN (online)	2173-5751
ISSN	2173-5751
DOI	10.1016/j.arbres.2021.04.020
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Article ; Online: Examining the Trajectory of Health-Related Quality of Life among Coronavirus Disease Patients.

Li, Jia / Wisnivesky, Juan P / Lin, Jenny J / Campbell, Kirk N / Hu, Liangyuan / Kale, Minal S

Journal of general internal medicine

2024

Abstract: Background: Recent studies have reported a reduction in health-related quality of life (HR-QoL) among post-coronavirus disease 2019 (COVID-19) patients. However, there remains a gap in research examining the heterogeneity and determinants of HR-QoL ... ...

Abstract	Background: Recent studies have reported a reduction in health-related quality of life (HR-QoL) among post-coronavirus disease 2019 (COVID-19) patients. However, there remains a gap in research examining the heterogeneity and determinants of HR-QoL trajectory in these patients. Objective: To describe and identify factors explaining the variability in HR-QoL trajectories among a cohort of patients with history of COVID-19. Design: A prospective study using data from a cohort of COVID-19 patients enrolled into a registry established at a health system in New York City. Participants: Participants were enrolled from July 2020 to June 2022, and completed a baseline evaluation and two follow-up visits at 6 and 12 months. Methods: We assessed HR-QoL with the 29-item Patient Reported Outcomes Measurement Information System instrument, which was summarized into mental and physical health domains. We performed latent class growth and multinomial logistic regression to examine trajectories of HR-QoL and identify factors associated with specific trajectories. Results: The study included 588 individuals with a median age of 52 years, 65% female, 54% White, 18% Black, and 18% Hispanic. We identified five physical health trajectories and four mental health trajectories. Female gender, having pre-existing hypertension, cardiovascular disease, asthma, and hospitalization for acute COVID-19 were independently associated with lower physical health. In addition, patients with increasing body mass index were more likely to experience lower physical health over time. Female gender, younger age, pre-existing asthma, arthritis and cardiovascular disease were associated with poor mental health. Conclusions: We found significant heterogeneity of HR-QoL after COVID-19, with women and patients with specific comorbidities at increased risk of lower HR-QoL. Implementation of targeted psychological and physical interventions is crucial for enhancing the quality of life of this patient population.
Language	English
Publishing date	2024-01-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	639008-0
ISSN	1525-1497 ; 0884-8734
ISSN (online)	1525-1497
ISSN	0884-8734
DOI	10.1007/s11606-023-08575-9
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Article ; Online: Lung Cancer Screening in Patients With Chronic Obstructive Pulmonary Disease: Do the Benefits Outweigh the Risks?

de-Torres, Juan P / Wisnivesky, Juan P

Archivos de bronconeumologia

2021 Volume 57, Issue 11, Page(s) 679–680

MeSH term(s)	Early Detection of Cancer ; Humans ; Lung Neoplasms/diagnosis ; Mass Screening ; Pulmonary Disease, Chronic Obstructive/complications ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Disease, Chronic Obstructive/epidemiology
Language	English
Publishing date	2021-09-22
Publishing country	Spain
Document type	Editorial
ZDB-ID	733126-5
ISSN	1579-2129 ; 0300-2896
ISSN (online)	1579-2129
ISSN	0300-2896
DOI	10.1016/j.arbr.2021.04.016
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Article ; Online: Assessing the Effect of Cancer Diagnosis on Beliefs about Comorbid Diabetes.

Muellers, Kimberly A / Harris, Yael T / Wisnivesky, Juan P / Lin, Jenny J

Seminars in oncology nursing

2023 Volume 39, Issue 4, Page(s) 151436

Abstract: Objectives: Increasingly, patients diagnosed with cancer also live with chronic comorbidities, and it is important to understand the impact of a new cancer diagnosis on perceptions about preexisting conditions. This study assessed the effect of cancer ... ...

Abstract	Objectives: Increasingly, patients diagnosed with cancer also live with chronic comorbidities, and it is important to understand the impact of a new cancer diagnosis on perceptions about preexisting conditions. This study assessed the effect of cancer diagnosis on beliefs about comorbid diabetes mellitus and assessed changes in beliefs about cancer and diabetes over time. Data sources: We recruited 75 patients with type 2 diabetes who were newly diagnosed with early-stage breast, prostate, lung, or colorectal cancer and 104 age-, sex-, and hemoglobin A1c-matched controls. Participants completed the Brief Illness Perception Questionnaire four times over 12 months. The authors examined within-patient and between-group differences in cancer and diabetes beliefs at baseline and over time. Results: Overall, diabetes beliefs did not differ between cancer patients and controls at baseline. Cancer patients' beliefs about diabetes varied significantly over time; they reported less concern about cancer, less emotional effect, and greater cancer knowledge over time. Participants without cancer were significantly more likely to report that diabetes affected their life across all time points, though this effect did not persist after adjustment for sociodemographic variables. Conclusion: While all patients' diabetes beliefs were similar at baseline and 12 months, cancer patients' beliefs about both illnesses fluctuated during the months following cancer diagnosis. Implications for nursing practice: Oncology nurses can play a key role in recognizing the effects of cancer diagnosis on beliefs about comorbid conditions and fluctuations in these beliefs during treatment. Assessing and communicating patient beliefs between oncology and other practitioners could produce more effective care plans based on patients' current outlook on their health.
MeSH term(s)	Male ; Humans ; Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/psychology ; Neoplasms/diagnosis
Language	English
Publishing date	2023-05-01
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	632682-1
ISSN	1878-3449 ; 0749-2081
ISSN (online)	1878-3449
ISSN	0749-2081
DOI	10.1016/j.soncn.2023.151436
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Article ; Online: Timely adherence to follow-up after high-risk lung cancer screenings.

Kee, Dustin / Sigel, Keith M / Wisnivesky, Juan P / Kale, Minal S

Journal of medical screening

2023 Volume 30, Issue 3, Page(s) 150–155

Abstract: Objective: To achieve the lung cancer screening (LCS) mortality benefit in clinical trials, timely, real-world follow-up of abnormal test results is necessary. Presently, annual LCS rates are lower than in trials, and adherence to follow-up after ... ...

Abstract	Objective: To achieve the lung cancer screening (LCS) mortality benefit in clinical trials, timely, real-world follow-up of abnormal test results is necessary. Presently, annual LCS rates are lower than in trials, and adherence to follow-up after suspicious findings has not been well studied. This study examined timely adherence to follow-up recommendations after positive low-dose computed tomography (LDCT) screenings. Methods: This retrospective study included individuals from two academic primary care practices in New York City who met United States Preventative Services Task Force LCS eligibility and had a positive LDCT scan between 2013 and 2020. They were recommended for shorter interval follow-up repeat computed tomography (CT), CT biopsy, or positron emission tomography/CT. Adherence was completion of the prescribed imaging by 15 days after the recommended 7-, 30-, and 90-day follow-up and by 30 days after the 180-day recommended follow-up. Results: Among 106 individuals with a positive LDCT scan, 64 (60%) were adherent to follow-up recommendations. Adherence was 72%, 63%, and 42% for recommended follow-ups of 30, 90, and 180 days, respectively. Being male was a predictor of a lower adherence rate. Among 23 individuals newly diagnosed with lung cancer after a positive LDCT scan, 83% were adherent to follow-up testing and 82% of cancers were Stage 1A or limited stage. Conclusions: There was variable adherence to the LCS follow-up recommendations despite positive screening CT, suggesting that even in a well-established screening program there may not be an efficient, systematic approach for follow-up. The delays in repeat testing potentially undermine the benefits of early detection.
MeSH term(s)	Humans ; Male ; United States ; Female ; Lung Neoplasms/diagnostic imaging ; Lung Neoplasms/pathology ; Retrospective Studies ; Early Detection of Cancer/methods ; Follow-Up Studies ; Tomography, X-Ray Computed/methods ; Mass Screening
Language	English
Publishing date	2023-03-14
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
ZDB-ID	1235253-6
ISSN	1475-5793 ; 0969-1413
ISSN (online)	1475-5793
ISSN	0969-1413
DOI	10.1177/09691413231162507
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Article ; Online: The "Nonadherent" Patient with Asthma: Time to Revise the Paradigm.

Wisnivesky, Juan P / Federman, Alex D

Annals of the American Thoracic Society

2019 Volume 16, Issue 6, Page(s) 676–677

MeSH term(s)	Asthma ; Child ; Hispanic Americans ; Humans ; Medication Adherence
Language	English
Publishing date	2019-05-31
Publishing country	United States
Document type	Journal Article ; Comment
ZDB-ID	2717461-X
ISSN	2325-6621 ; 1943-5665 ; 2325-6621
ISSN (online)	2325-6621 ; 1943-5665
ISSN	2325-6621
DOI	10.1513/AnnalsATS.201902-141ED
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Article ; Online: Inflammatory markers in world trade center workers with asthma: Associations with post traumatic stress disorder.

Wisnivesky, Juan P / Agrawal, Nikita / Ankam, Jyoti / Gonzalez, Adam / Federman, Alex / Markowitz, Steven B / Birmingham, Janette M / Busse, Paula J

PloS one

2024 Volume 19, Issue 2, Page(s) e0297616

Abstract: ... in the study, 75 (32%) had PTSD. PTSD was significantly associated with worse asthma control (p = 0.002) and ... increased resource utilization (p = 0.0002). There was no significant association (p>0.05) between most ...

Abstract	Background: Post-traumatic stress disorders (PTSD) is associated with worse asthma outcomes in individuals exposed to the World Trade Center (WTC) site. Research question: Do WTC workers with coexisting PTSD and asthma have a specific inflammatory pattern that underlies the relationship with increased asthma morbidity? Study design and methods: We collected data on a cohort of WTC workers with asthma recruited from the WTC Health Program. Diagnosis of PTSD was ascertained with a Structured Clinical Interview for DSM-5 (Diagnostic and Statistical Manuel of Mental Disorders) and the severity of PTSD symptoms was assessed with the PTSD Checklist 5. We obtained blood and sputum samples to measure cytokines levels in study participants. Results: Of the 232 WTC workers with diagnosis of asthma in the study, 75 (32%) had PTSD. PTSD was significantly associated with worse asthma control (p = 0.002) and increased resource utilization (p = 0.0002). There was no significant association (p>0.05) between most blood or sputum cytokines with PTSD diagnosis or PCL-5 scores both in unadjusted and adjusted analyses. Interpretation: Our results suggest that PTSD is not associated with blood and sputum inflammatory markers in WTC workers with asthma. These findings suggest that other mechanisms likely explain the association between PTSD and asthma control in WTC exposed individuals.
MeSH term(s)	Humans ; Stress Disorders, Post-Traumatic/epidemiology ; Stress Disorders, Post-Traumatic/diagnosis ; Asthma/complications ; Asthma/epidemiology ; Morbidity ; Cytokines ; September 11 Terrorist Attacks
Chemical Substances	Cytokines
Language	English
Publishing date	2024-02-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0297616
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