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  1. Article ; Online: Is hyponatremia a novel marker of inflammation in patients with COVID-19?

    Ayus, Juan Carlos / Kalantar-Zadeh, Kamyar / Tantisattamo, Ekamol / Rhee, Connie M / Negri, Armando L

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2023  Volume 38, Issue 8, Page(s) 1921–1924

    MeSH term(s) Humans ; Hyponatremia/diagnosis ; Hyponatremia/etiology ; COVID-19/complications ; Inflammation ; Sodium
    Chemical Substances Sodium (9NEZ333N27)
    Language English
    Publishing date 2023-03-29
    Publishing country England
    Document type Letter
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfad111
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2198: Show issues Location:
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  2. Article ; Online: A comment on the question 'Are the aims of the K/DOQI guidelines for mineral metabolism disorders in stages 3-5 chronic kidney disease unachievable or inadequate?

    Negri, Armando L

    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia

    2013  Volume 33, Issue 3, Page(s) 424

    MeSH term(s) Bone and Bones/metabolism ; Humans ; Kidney Failure, Chronic/metabolism ; Kidney Failure, Chronic/therapy ; Renal Dialysis
    Language Spanish
    Publishing date 2013
    Publishing country Spain
    Document type Comment ; Letter
    ZDB-ID 632512-9
    ISSN 1989-2284 ; 0211-6995
    ISSN (online) 1989-2284
    ISSN 0211-6995
    DOI 10.3265/Nefrologia.pre2013.Apr.11941
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 56: Show issues

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  3. Article ; Online: Stilbenes, phenanthrenes and antiproliferative activity of

    Ghiraldi, Denise M B / Perin, Paula C / Lucca, Diego L / Pilau, Eduardo J / de Oliveira, Silvana M / Diniz, Beatriz V / Negri, Melyssa F N / Milaneze-Gutierre, Maria A / Martinelli, Fabiana T R / Berlinck, Roberto G S / Pomini, Armando M

    Natural product research

    2023  , Page(s) 1–10

    Abstract: The phytochemical study ... ...

    Abstract The phytochemical study of
    Language English
    Publishing date 2023-12-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2023.2290150
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  4. Article ; Online: Erratum to: Calcitriol resistance in hemodialysis patients with secondary hyperparathyroidism.

    Negri, Armando L / Brandenburg, Vincent M

    International urology and nephrology

    2015  Volume 47, Issue 2, Page(s) 421

    Language English
    Publishing date 2015-02
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 204048-7
    ISSN 1573-2584 ; 0301-1623 ; 0042-1162
    ISSN (online) 1573-2584
    ISSN 0301-1623 ; 0042-1162
    DOI 10.1007/s11255-014-0898-4
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    Zs.A 733: Show issues Location:
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  5. Article: Hyponatremia, Inflammation at Admission, and Mortality in Hospitalized COVID-19 Patients: A Prospective Cohort Study.

    Ayus, Juan Carlos / Negri, Armando Luis / Moritz, Michael L / Lee, Kyung Min / Caputo, Daniel / Borda, Maria Elena / Go, Alan S / Eghi, Carlos

    Frontiers in medicine

    2021  Volume 8, Page(s) 748364

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2021-12-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2021.748364
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  6. Article: Phosphate binders, cardiovascular calcifications and mortality: do we need another survival study with sevelamer?

    Negri, Armando L

    Journal of nephrology

    2010  Volume 23, Issue 6, Page(s) 653–657

    Abstract: In chronic renal failure patients, hyperphosphatemia has been associated with vascular calcifications and increased cardiovascular morbidity and mortality. In vitro observations have shown that calcium and phosphate independently and synergistically ... ...

    Abstract In chronic renal failure patients, hyperphosphatemia has been associated with vascular calcifications and increased cardiovascular morbidity and mortality. In vitro observations have shown that calcium and phosphate independently and synergistically induce calcifications in human vascular smooth muscle cells, suggesting an important role for both in the calcification process. Because non-calcium phosphate binders reduce serum phosphate without increasing the calcium load, as is the case with calcium-based phosphate binders, it has been speculated that treatment with sevelamer leads to less vascular calcification and better survival in chronic kidney disease. Although the use of sevelamer may slow the progression of vascular calcifications compared with calcium-based phosphate binders, the relationship of this surrogate marker with patients' cardiovascular mortality and survival is far from certain. To resolve this uncertainty and to determine the most cost-effective way to treat hyperphosphatemia in patients with end-stage renal disease, another randomized study analyzing mortality comparing sevelamer with calcium phosphate binders should be undertaken.
    MeSH term(s) Animals ; Calcinosis/drug therapy ; Calcinosis/mortality ; Calcium/metabolism ; Cardiovascular Diseases/mortality ; Chelating Agents/therapeutic use ; Hospitalization ; Humans ; Hyperphosphatemia/complications ; Hyperphosphatemia/drug therapy ; Kidney Failure, Chronic/complications ; Muscle, Smooth, Vascular/metabolism ; Phosphates/metabolism ; Polyamines/therapeutic use ; Renal Dialysis ; Sevelamer
    Chemical Substances Chelating Agents ; Phosphates ; Polyamines ; Sevelamer (9YCX42I8IU) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2010-11
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 1093991-x
    ISSN 1724-6059 ; 1121-8428 ; 1120-3625
    ISSN (online) 1724-6059
    ISSN 1121-8428 ; 1120-3625
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    Zs.A 3369: Show issues Location:
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  7. Article: Chronicity of Uncorrected Hyponatremia and Clinical Outcomes in Older Patients Undergoing Hip Fracture Repair.

    Ayus, Juan Carlos / Fuentes, Nora / Go, Alan S / Achinger, Steven G / Moritz, Michael L / Nigwekar, Sagar U / Waikar, Sushrut S / Negri, Armando Luis

    Frontiers in medicine

    2020  Volume 7, Page(s) 263

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2020-06-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2020.00263
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  8. Article ; Online: Association of oral calcitriol with improved survival in non-dialysed and dialysed patients with CKD.

    Negri, Armando L

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2009  Volume 24, Issue 2, Page(s) 341–344

    MeSH term(s) Administration, Oral ; Calcitriol/administration & dosage ; Humans ; Kidney Failure, Chronic/drug therapy ; Kidney Failure, Chronic/mortality ; Kidney Failure, Chronic/therapy ; Receptors, Calcitriol/agonists ; Renal Dialysis ; Renal Insufficiency, Chronic/drug therapy ; Renal Insufficiency, Chronic/mortality ; Renal Insufficiency, Chronic/therapy ; Survival Rate
    Chemical Substances Receptors, Calcitriol ; Calcitriol (FXC9231JVH)
    Language English
    Publishing date 2009-02
    Publishing country England
    Document type Editorial ; Review
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfn624
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  9. Article: Hereditary hypophosphatemias: new genes in the bone-kidney axis.

    Negri, Armando L

    Nephrology (Carlton, Vic.)

    2007  Volume 12, Issue 4, Page(s) 317–320

    Abstract: Hypophosphatemia due to isolated renal phosphate wasting is a genetically heterogeneous disease. Two new genes linked to two different forms of hereditary hypophosphatemias have recently been described. Autosomal recessive form of hypophosphatemic ... ...

    Abstract Hypophosphatemia due to isolated renal phosphate wasting is a genetically heterogeneous disease. Two new genes linked to two different forms of hereditary hypophosphatemias have recently been described. Autosomal recessive form of hypophosphatemic rickets was mapped to chromosome 4q21 and identified homozygous mutations in dentin matrix protein 1 (DMP1) gene, which encodes a non-collagenous bone matrix protein. Intact plasma levels of the phosphaturic protein FGF23 (fibroblast growth factor 23) were clearly elevated in some of the affected individuals, providing a possible explanation for the phosphaturia and inappropriately normal 1,25(OH)2D levels, and suggesting that DMP1 may regulate FGF23 expression. Hereditary hypophosphatemic rickets with hypercalciuria is another rare disorder of autosomal recessive inheritance. Affected individuals present with hypercalciuria due to increased serum 1,25-dihydroxyvitamin D levels and increased intestinal calcium absorption. The disease was mapped to a 1.6 Mbp region on chromosome 9q34, which contains SLC34A3, the gene encoding the renal sodium-phosphate cotransporter NaPi-IIc. This was the first demonstration that NaPi-IIc has a key role in the regulation of phosphate homeostasis. Thus, DMP1 and NaPi-IIc add two new members to the bone-kidney axis proposed since it was discovered that the first phosphatonin, FGF23, was of osteoblastic/osteocyte origin. This provides a mechanism for the skeleton to communicate with the kidney to coordinate the mineralization of extracelular matrix and the renal handling of phosphate.
    MeSH term(s) Extracellular Matrix Proteins/genetics ; Humans ; Hypophosphatemia/genetics ; Mutation ; Phosphoproteins/genetics ; Sodium-Phosphate Cotransporter Proteins, Type IIc/genetics
    Chemical Substances DMP1 protein, human ; Extracellular Matrix Proteins ; Phosphoproteins ; SLC34A3 protein, human ; Sodium-Phosphate Cotransporter Proteins, Type IIc
    Language English
    Publishing date 2007-08
    Publishing country Australia
    Document type Journal Article ; Review
    ZDB-ID 1303661-0
    ISSN 1440-1797 ; 1320-5358
    ISSN (online) 1440-1797
    ISSN 1320-5358
    DOI 10.1111/j.1440-1797.2007.00824.x
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  10. Article ; Online: Weekly number of hours of treatment is critical when evaluating mortality in in-center daily dialysis.

    Ayus, Juan C / Achinger, Steven G / Negri, Armando L

    Kidney international

    2013  Volume 84, Issue 2, Page(s) 409

    MeSH term(s) Female ; Humans ; Male ; Renal Dialysis/mortality
    Language English
    Publishing date 2013-08
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1038/ki.2013.159
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