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  1. Article ; Online: Be aware of misdiagnosis-Influenza A H1N1 in a pregnant patient with suspected COVID-19.

    Fang, He / Xingfei, Pan / Yingwei, Qiu / Dunjin, Chen

    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

    2020  Volume 150, Issue 1, Page(s) 119–121

    Keywords covid19
    Language English
    Publishing date 2020-05-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80149-5
    ISSN 1879-3479 ; 0020-7292
    ISSN (online) 1879-3479
    ISSN 0020-7292
    DOI 10.1002/ijgo.13183
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    Zs.A 355: Show issues Location:
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  2. Article ; Online: Correction to: Characteristics of splenic PD-1

    Chen, Dianhui / Mo, Feng / Liu, Meiling / Liu, Lin / Xing, Junmin / Xiao, Wei / Gong, Yumei / Tang, Shanni / Tan, Zhengrong / Liang, Guikuan / Xie, Hongyan / Huang, Jun / Shen, Juan / Pan, Xingfei

    Immunologic research

    2024  

    Language English
    Publishing date 2024-02-29
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 632857-x
    ISSN 1559-0755 ; 0257-277X
    ISSN (online) 1559-0755
    ISSN 0257-277X
    DOI 10.1007/s12026-024-09469-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Chronic Hepatitis B in Women of Childbearing Age and Pregnant Women in China: A Cross-Sectional Study.

    Zhou, Liyang / Liu, Xitao / Ou, Xueting / Sheng, Qiongyu / Situ, Bing / He, Fang / Pan, Xingfei

    The American journal of tropical medicine and hygiene

    2024  Volume 110, Issue 4, Page(s) 719–723

    Abstract: Pregnant women and women of childbearing age were enrolled in our study and their knowledge about the Hepatitis B virus (HBV) and chronic hepatitis B (CHB) was evaluated. A questionnaire was distributed to every woman in the cross-sectional study. The ... ...

    Abstract Pregnant women and women of childbearing age were enrolled in our study and their knowledge about the Hepatitis B virus (HBV) and chronic hepatitis B (CHB) was evaluated. A questionnaire was distributed to every woman in the cross-sectional study. The questionnaire was answered by all participants before they received health education and advice about HBV and CHB from the doctors visited. Data collected from all answers were analyzed using the χ2 test and logistic regression models. A total of 206 pregnant women and women of childbearing age with CHB infection were enrolled in the study during their first visit to the Infectious Diseases Clinic of the Third Affiliated Hospital of Guangzhou Medical University. Some women of childbearing age (40.8%) and pregnant women with CHB infection (30.6%) still believed HBV could be transmitted through diet and/or mosquito bites. Some women of childbearing age and pregnant women with CHB infection had limited knowledge of the prevention of HBV transmission (111 of 206, 53.9%). Women with higher levels of education had more knowledge about HBV (senior middle school, P = 0.02; university, P <0.01). The majority of participants were willing to take antiviral medicine to decrease the mother-to-child transmission (MTCT) rate of HBV. Some women of childbearing age and/or pregnant women with CHB infection have relatively limited knowledge about HBV or CHB. This situation contributes to the timeliness, or lack thereof, of these women with CHB to see a doctor and receive antiviral therapy. As a result, the morbidity and mortality of HBV-related complications could increase along with the rate of MTCT of HBV.
    MeSH term(s) Female ; Pregnancy ; Humans ; Hepatitis B, Chronic/epidemiology ; Hepatitis B, Chronic/prevention & control ; Pregnant Women ; Cross-Sectional Studies ; Pregnancy Complications, Infectious ; Infectious Disease Transmission, Vertical/prevention & control ; Hepatitis B virus/genetics ; China/epidemiology ; Hepatitis B/prevention & control ; Hepatitis B Surface Antigens ; DNA, Viral
    Chemical Substances Hepatitis B Surface Antigens ; DNA, Viral
    Language English
    Publishing date 2024-03-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2942-7
    ISSN 1476-1645 ; 0002-9637
    ISSN (online) 1476-1645
    ISSN 0002-9637
    DOI 10.4269/ajtmh.23-0217
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  4. Article ; Online: Detection of macrolide and fluoroquinolone resistance-associated 23S rRNA and parC mutations in Mycoplasma genitalium by nested real-time PCR.

    He, Wenyin / Yuan, Ying / Liang, Junyu / Fan, Xuejiao / Li, Lei / Pan, Xingfei

    Frontiers in cellular and infection microbiology

    2023  Volume 13, Page(s) 1271392

    Abstract: Background: Traditional drug susceptibility testing cannot be performed in clinical laboratories due to the slow-growing characteristics of : Objective: Sequencing analysis can detect unknown mutations, but it is time-consuming, requires professional ...

    Abstract Background: Traditional drug susceptibility testing cannot be performed in clinical laboratories due to the slow-growing characteristics of
    Objective: Sequencing analysis can detect unknown mutations, but it is time-consuming, requires professional analytical skills and the appropriate testing equipment. The main objective of this study was to establish a nested real-time PCR method for the simultaneous detection of
    Results: 105 MG-positive samples and 27 samples containing other pathogens were used for validation. The limit of the nested real-time PCR detection was 500 copies/reaction and there was no cross-reaction with
    Conclusions: The results of this sensitive and rapid alternative for identifying resistant genotypes of
    MeSH term(s) Humans ; Fluoroquinolones/pharmacology ; Mycoplasma genitalium/genetics ; RNA, Ribosomal, 23S/genetics ; Real-Time Polymerase Chain Reaction ; Macrolides/pharmacology ; Microbial Sensitivity Tests ; Drug Resistance, Bacterial/genetics ; Mycoplasma Infections/diagnosis ; Mycobacterium tuberculosis/genetics ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Mutation
    Chemical Substances Fluoroquinolones ; RNA, Ribosomal, 23S ; Macrolides ; Anti-Bacterial Agents
    Language English
    Publishing date 2023-10-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2023.1271392
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Characteristics of splenic PD-1

    Chen, Dianhui / Mo, Feng / Liu, Meiling / Liu, Lin / Xing, Junmin / Xiao, Wei / Gong, Yumei / Tang, Shanni / Tan, Zhengrong / Liang, Guikuan / Xie, Hongyan / Huang, Jun / Shen, Juan / Pan, Xingfei

    Immunologic research

    2024  

    Abstract: Although the functions of programmed death-1 (PD-1) on αβ T cells have been extensively reported, a role for PD-1 in regulating γδT cell function is only beginning to emerge. Here, we investigated the phenotypic and functional characteristics of PD-1- ... ...

    Abstract Although the functions of programmed death-1 (PD-1) on αβ T cells have been extensively reported, a role for PD-1 in regulating γδT cell function is only beginning to emerge. Here, we investigated the phenotypic and functional characteristics of PD-1-expressing γδT cells, and the molecular mechanism was also explored in the Plasmodium yoelii nigeriensis (P. yoelii NSM)-infected mice. Flow cytometry and single-cell RNA sequencing (scRNA-seq) were performed. An inverse agonist of RORα, SR3335, was used to investigate the role of RORα in regulating PD-1
    Language English
    Publishing date 2024-01-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632857-x
    ISSN 1559-0755 ; 0257-277X
    ISSN (online) 1559-0755
    ISSN 0257-277X
    DOI 10.1007/s12026-023-09441-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Be aware of misdiagnosis—Influenza A H1N1 in a pregnant patient with suspected COVID‐19

    Fang, He / Xingfei, Pan / Yingwei, Qiu / Dunjin, Chen

    International Journal of Gynecology & Obstetrics

    2020  Volume 150, Issue 1, Page(s) 119–121

    Keywords Obstetrics and Gynaecology ; General Medicine ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ZDB-ID 80149-5
    ISSN 1879-3479 ; 0020-7292
    ISSN (online) 1879-3479
    ISSN 0020-7292
    DOI 10.1002/ijgo.13183
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    In stock of ZB MED Cologne/Königswinter

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  8. Article ; Online: Association of IL-32 rs28372698 polymorphism with active chronic HBV infection.

    Zheng, Shuo / Li, Mei / Pan, Xingfei / Huang, Xiaoping

    Journal of medical virology

    2021  Volume 93, Issue 11, Page(s) 6236–6240

    Abstract: Interleukin-32 (IL-32), a multiple proinflammatory cytokine, plays a vital role in immune-related diseases and infectious diseases. The promoter region of IL-32, which showed functional polymorphism, could regulate IL-32 expression. Although IL-32 ... ...

    Abstract Interleukin-32 (IL-32), a multiple proinflammatory cytokine, plays a vital role in immune-related diseases and infectious diseases. The promoter region of IL-32, which showed functional polymorphism, could regulate IL-32 expression. Although IL-32 rs28372698 polymorphism has been related to a lot of inflammatory diseases, the association of IL-32 rs28372698 polymorphism with a hepatic flare of chronic HBV infection has not been reported. In the present study, IL-32 rs28372698 polymorphism was genotyped in 104 chronic HBV carriers and 151 active chronic hepatitis B (CHB) patients. The frequency of IL-32 T/T genotype in patients with active CHB was significantly higher than that in chronic HBV carriers. Furthermore, the frequency of the T allele at IL-32 rs28372698 in active CHB patients was also higher than that in chronic HBV carriers. The serum level of IL-32 in active CHB patients was higher than that in chronic HBV carriers. Our results imply that IL-32 T/T polymorphism might be associated with a hepatic flare of chronic HBV infection.
    MeSH term(s) Adult ; Female ; Genotype ; Hepatitis B virus/pathogenicity ; Hepatitis B, Chronic/genetics ; Hepatitis B, Chronic/virology ; Humans ; Interleukins/genetics ; Male ; Polymorphism, Single Nucleotide ; Young Adult
    Chemical Substances IL32 protein, human ; Interleukins
    Language English
    Publishing date 2021-06-23
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.27140
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  9. Article ; Online: Repeat laboratory testing of SARS-CoV-2 is necessary to diagnose COVID-19

    Guilong Zhuang / Xueting Ou / Liyang Zhou / Xingfei Pan / Guohang Li

    Journal of Infection and Public Health, Vol 14, Iss 9, Pp 1164-

    2021  Volume 1168

    Abstract: The pandemic of corona virus disease 2019 (COVID-19) caused by SARS-CoV-2 is ravaging the world. Diagnosis and isolation of persons who are infected with SARS-CoV-2 is very important medical emergency to contain the epidemic of COVID-19. To date, the ... ...

    Abstract The pandemic of corona virus disease 2019 (COVID-19) caused by SARS-CoV-2 is ravaging the world. Diagnosis and isolation of persons who are infected with SARS-CoV-2 is very important medical emergency to contain the epidemic of COVID-19. To date, the diagnosis of COVID-19 is mainly depending on positive quantitative reverse transcriptase polymerase chain reaction (qRT-PCR) results for SARS-CoV-2. In the present study, we reported that two cases with uncommon symptoms from a family cluster were ultimately diagnosed as COVID-19 after more than twice of collecting samples and qRT-PCR tests were done. It is easily to miss diagnosis of COVID-19 especially for patients with uncommon symptoms. More attention should be paid to observe the clinical characteristics of it and invent more accurate and convenient methods to detect SARS-CoV-2 as soon as possible.
    Keywords Repeat ; Laboratory ; Test ; SARS-CoV-2 ; COVID-19 ; Infectious and parasitic diseases ; RC109-216 ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2021-09-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Repeat laboratory testing of SARS-CoV-2 is necessary to diagnose COVID-19.

    Zhuang, Guilong / Ou, Xueting / Zhou, Liyang / Pan, Xingfei / Li, Guohang

    Journal of infection and public health

    2021  Volume 14, Issue 9, Page(s) 1164–1168

    Abstract: The pandemic of corona virus disease 2019 (COVID-19) caused by SARS-CoV-2 is ravaging the world. Diagnosis and isolation of persons who are infected with SARS-CoV-2 is very important medical emergency to contain the epidemic of COVID-19. To date, the ... ...

    Abstract The pandemic of corona virus disease 2019 (COVID-19) caused by SARS-CoV-2 is ravaging the world. Diagnosis and isolation of persons who are infected with SARS-CoV-2 is very important medical emergency to contain the epidemic of COVID-19. To date, the diagnosis of COVID-19 is mainly depending on positive quantitative reverse transcriptase polymerase chain reaction (qRT-PCR) results for SARS-CoV-2. In the present study, we reported that two cases with uncommon symptoms from a family cluster were ultimately diagnosed as COVID-19 after more than twice of collecting samples and qRT-PCR tests were done. It is easily to miss diagnosis of COVID-19 especially for patients with uncommon symptoms. More attention should be paid to observe the clinical characteristics of it and invent more accurate and convenient methods to detect SARS-CoV-2 as soon as possible.
    MeSH term(s) COVID-19 ; Clinical Laboratory Techniques ; False Negative Reactions ; Humans ; Pandemics ; Reverse Transcriptase Polymerase Chain Reaction ; SARS-CoV-2
    Language English
    Publishing date 2021-07-20
    Publishing country England
    Document type Case Reports
    ZDB-ID 2467587-8
    ISSN 1876-035X ; 1876-0341
    ISSN (online) 1876-035X
    ISSN 1876-0341
    DOI 10.1016/j.jiph.2021.07.008
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