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  1. Article ; Online: Global Health Imperative to Prioritizing Cardiovascular Education.

    Haynes, Norrisa / Saint-Joy, Veauthyelau / Swain, JaBaris

    Journal of the American College of Cardiology

    2021  Volume 77, Issue 21, Page(s) 2749–2753

    MeSH term(s) Cardiologists/education ; Cardiology/education ; Cardiovascular Diseases/therapy ; Global Health ; Haiti ; Humans ; International Cooperation
    Language English
    Publishing date 2021-05-27
    Publishing country United States
    Document type Editorial
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2021.03.326
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Racial and Ethnic Disparities in Cancer-Associated Thrombosis.

    Wiredu, Courteney / Haynes, Norrisa / Guerra, Carmen / Ky, Bonnie

    Thrombosis and haemostasis

    2022  Volume 122, Issue 5, Page(s) 662–665

    Abstract: Active malignancy increases the risk of developing venous thromboembolism (VTE) by four- to seven-fold. The risk of VTE, including deep vein thrombosis and pulmonary embolism, in patients with cancer varies based on several clinical factors, such as ... ...

    Abstract Active malignancy increases the risk of developing venous thromboembolism (VTE) by four- to seven-fold. The risk of VTE, including deep vein thrombosis and pulmonary embolism, in patients with cancer varies based on several clinical factors, such as cancer stage and age. However, race and ethnicity are also associated with increased VTE risk. Black (African American) patients with cancer have a higher risk of developing VTE than White patients, while Asian/Pacific Islanders have a lower risk. Studies on cancer-associated thrombosis demonstrate a need to advance our understanding of both the biologic and sociologic underpinnings of the observed differences according to race. Addressing the causes of these disparities can better health outcomes for historically underserved patient populations.
    MeSH term(s) Ethnicity ; Humans ; Incidence ; Neoplasms/complications ; Risk Factors ; Thrombosis/etiology ; Venous Thromboembolism/epidemiology ; Venous Thromboembolism/etiology
    Language English
    Publishing date 2022-01-20
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 518294-3
    ISSN 2567-689X ; 0340-6245
    ISSN (online) 2567-689X
    ISSN 0340-6245
    DOI 10.1055/a-1674-0259
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Partnering With Barbershops and Salons to Engage Vulnerable Communities During the COVID-19 Pandemic.

    Hill, Krystal / Haynes, Norrisa / Momplaisir, Florence

    Open forum infectious diseases

    2021  Volume 8, Issue 7, Page(s) ofab191

    Abstract: This manuscript conveys the story of the health and economic challenges faced by a coalition of barbershops and salons in West Philadelphia. It is grounded in city and national data that illustrate the widening racial and class disparities during ... ...

    Abstract This manuscript conveys the story of the health and economic challenges faced by a coalition of barbershops and salons in West Philadelphia. It is grounded in city and national data that illustrate the widening racial and class disparities during coronavirus disease 2019. Ultimately, it is a story of resilience that outlines a budding partnership between barbershop and salon owners, their community, and medical providers.
    Language English
    Publishing date 2021-04-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofab191
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: At the Heart of the Matter: Unmasking and Addressing the Toll of COVID-19 on Diverse Populations.

    Haynes, Norrisa / Cooper, Lisa A / Albert, Michelle A

    Circulation

    2020  Volume 142, Issue 2, Page(s) 105–107

    MeSH term(s) Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/epidemiology ; Coronavirus Infections/ethnology ; Coronavirus Infections/pathology ; Diabetes Complications/ethnology ; Diabetes Complications/pathology ; Economic Recession ; Food Supply ; Healthcare Disparities/ethnology ; Humans ; Hypertension/complications ; Hypertension/epidemiology ; Hypertension/ethnology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/ethnology ; Pneumonia, Viral/pathology ; Quarantine/methods ; SARS-CoV-2 ; United States/epidemiology
    Keywords covid19
    Language English
    Publishing date 2020-05-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.120.048126
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Community-Based Participatory Research to Improve Cardiovascular Health Among US Racial and Ethnic Minority Groups.

    Haynes, Norrisa / Kaur, Amanpreet / Swain, JaBaris / Joseph, Joshua J / Brewer, LaPrincess C

    Current epidemiology reports

    2022  Volume 9, Issue 3, Page(s) 212–221

    Abstract: Purpose of review: This review aims to assess the contemporary community-based participatory research (CBPR) literature seeking to improve the cardiovascular health of racial and ethnic minority groups in the USA with a higher burden of cardiovascular ... ...

    Abstract Purpose of review: This review aims to assess the contemporary community-based participatory research (CBPR) literature seeking to improve the cardiovascular health of racial and ethnic minority groups in the USA with a higher burden of cardiovascular risk factors and social determinants of health. It summarizes recent CBPR studies based on the American Heart Association Life's Simple 7 (LS7) framework, delineating seven modifiable health behaviors and clinical factors to promote cardiovascular health.
    Recent findings: Although limited in quantity, studies demonstrated preliminary effectiveness in improving individual and a composite of LS7 indicators by employing strategies centered around fortifying social networks, integrating group activities, leveraging technology, incorporating faith-based and spiritual practices, and implementing changes to the built environment.
    Summary: Future directions for investigators engaged in CBPR include building on the existing body of evidence through more comprehensive studies, scaling effective interventions, and translating CBPR findings to influence health policy to better address health disparities.
    Language English
    Publishing date 2022-07-11
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2196-2995
    ISSN 2196-2995
    DOI 10.1007/s40471-022-00298-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Education and Training Models for Remote Learning.

    Forbes, Victoria E / Chamberlin, Mary D / Dusabejambo, Vincent / Walker, Tim / Bensen, Steve P / Haynes, Norrisa / Nunes, Kathryn / Saint-Joy, Veauthyelau / Makrauer, Frederick L

    Hematology/oncology clinics of North America

    2023  Volume 38, Issue 1, Page(s) 185–197

    Abstract: Our international partnerships have fostered longstanding collaborative relationships leading to the development of unique, locally-designed, and sustainable training programs that serve as models for global health education and cooperation. ...

    Abstract Our international partnerships have fostered longstanding collaborative relationships leading to the development of unique, locally-designed, and sustainable training programs that serve as models for global health education and cooperation.
    MeSH term(s) Education, Distance ; Models, Educational
    Language English
    Publishing date 2023-08-26
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 93115-9
    ISSN 1558-1977 ; 0889-8588
    ISSN (online) 1558-1977
    ISSN 0889-8588
    DOI 10.1016/j.hoc.2023.06.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Next Generation, Modifiable Cardiometabolic Biomarkers: Mitochondrial Adaptation and Metabolic Resilience: A Scientific Statement From the American Heart Association.

    Mietus-Snyder, Michele / Perak, Amanda M / Cheng, Susan / Hayman, Laura L / Haynes, Norrisa / Meikle, Peter J / Shah, Svati H / Suglia, Shakira F

    Circulation

    2023  Volume 148, Issue 22, Page(s) 1827–1845

    Abstract: Cardiometabolic risk is increasing in prevalence across the life span with disproportionate ramifications for youth at socioeconomic disadvantage. Established risk factors and associated disease progression are harder to reverse as they become entrenched ...

    Abstract Cardiometabolic risk is increasing in prevalence across the life span with disproportionate ramifications for youth at socioeconomic disadvantage. Established risk factors and associated disease progression are harder to reverse as they become entrenched over time; if current trends are unchecked, the consequences for individual and societal wellness will become untenable. Interrelated root causes of ectopic adiposity and insulin resistance are understood but identified late in the trajectory of systemic metabolic dysregulation when traditional cardiometabolic risk factors cross current diagnostic thresholds of disease. Thus, children at cardiometabolic risk are often exposed to suboptimal metabolism over years before they present with clinical symptoms, at which point life-long reliance on pharmacotherapy may only mitigate but not reverse the risk. Leading-edge indicators are needed to detect the earliest departure from healthy metabolism, so that targeted, primordial, and primary prevention of cardiometabolic risk is possible. Better understanding of biomarkers that reflect the earliest transitions to dysmetabolism, beginning in utero, ideally biomarkers that are also mechanistic/causal and modifiable, is critically needed. This scientific statement explores emerging biomarkers of cardiometabolic risk across rapidly evolving and interrelated "omic" fields of research (the epigenome, microbiome, metabolome, lipidome, and inflammasome). Connections in each domain to mitochondrial function are identified that may mediate the favorable responses of each of the omic biomarkers featured to a heart-healthy lifestyle, notably to nutritional interventions. Fuller implementation of evidence-based nutrition must address environmental and socioeconomic disparities that can either facilitate or impede response to therapy.
    MeSH term(s) Child ; Adolescent ; Humans ; American Heart Association ; Risk Factors ; Obesity/complications ; Biomarkers ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/prevention & control
    Chemical Substances Biomarkers
    Language English
    Publishing date 2023-10-30
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIR.0000000000001185
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Study Protocol for the Artificial Intelligence-Driven Evaluation of Structural Heart Diseases Using Wearable Electrocardiogram (ID-SHD).

    Aminorroaya, Arya / Dhingra, Lovedeep Singh / Camargos, Aline Pedroso / Shankar, Sumukh Vasisht / Khunte, Akshay / Sangha, Veer / McNamara, Robert L / Haynes, Norrisa / Oikonomou, Evangelos K / Khera, Rohan

    medRxiv : the preprint server for health sciences

    2024  

    Abstract: Introduction: Portable devices capable of electrocardiogram (ECG) acquisition have the potential to enhance structural heart disease (SHD) management by enabling early detection through artificial intelligence-ECG (AI-ECG) algorithms. However, the ... ...

    Abstract Introduction: Portable devices capable of electrocardiogram (ECG) acquisition have the potential to enhance structural heart disease (SHD) management by enabling early detection through artificial intelligence-ECG (AI-ECG) algorithms. However, the performance of these AI algorithms for identifying SHD in a real-world screening setting is unknown. To address this gap, we aim to evaluate the validity of our wearable-adapted AI algorithm, which has been previously developed and validated for detecting SHD from single-lead portable ECGs in patients undergoing routine echocardiograms in the Yale New Haven Hospital (YNHH).
    Research methods and analysis: This is the protocol for a cross-sectional study in the echocardiographic laboratories of YNHH. The study will enroll 585 patients referred for outpatient transthoracic echocardiogram (TTE) as part of their routine clinical care. Patients expressing interest in participating in the study will undergo a screening interview, followed by enrollment upon meeting eligibility criteria and providing informed consent. During their routine visit, patients will undergo a 1-lead ECG with two devices - one with an Apple Watch and the second with another portable 1-lead ECG device. With participant consent, these 1-lead ECG data will be linked to participant demographic and clinical data recorded in the YNHH electronic health records (EHR). The study will assess the performance of the AI-ECG algorithm in identifying SHD, including left ventricular systolic dysfunction (LVSD), valvular disease and severe left ventricular hypertrophy (LVH), by comparing the algorithm's results with data obtained from TTE, which is the established gold standard for diagnosing SHD.
    Ethics and dissemination: All patient EHR data required for assessing eligibility and conducting the AI-ECG will be accessed through secure servers approved for protected health information. Data will be maintained on secure, encrypted servers for a minimum of five years after the publication of our findings in a peer-reviewed journal, and any unanticipated adverse events or risks will be reported by the principal investigator to the Yale Institutional Review Board, which has reviewed and approved this protocol (Protocol Number: 2000035532).
    Language English
    Publishing date 2024-03-19
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2024.03.18.24304477
    Database MEDical Literature Analysis and Retrieval System OnLINE

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