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  1. Article ; Online: Editorial: A Successful Translational Story, from Scientific Discoveries to A Breakthrough Therapy for Atopic Dermatitis.

    De Benedetto, Anna

    Dermatitis : contact, atopic, occupational, drug

    2024  Volume 35, Issue S1, Page(s) S4–S6

    MeSH term(s) Humans ; Dermatitis, Atopic/therapy
    Language English
    Publishing date 2024-02-06
    Publishing country United States
    Document type Editorial
    ZDB-ID 2144723-8
    ISSN 2162-5220 ; 1532-8163 ; 1710-3568
    ISSN (online) 2162-5220 ; 1532-8163
    ISSN 1710-3568
    DOI 10.1089/derm.2023.0423
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Recalcitrant palmoplantar pustulosis controlled with dupilumab.

    Smith, Hannah D / Montoya, Liliana / De Benedetto, Anna

    JAAD case reports

    2023  Volume 35, Page(s) 33–37

    Language English
    Publishing date 2023-03-07
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834220-3
    ISSN 2352-5126
    ISSN 2352-5126
    DOI 10.1016/j.jdcr.2023.02.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Erythema Multiforme Secondary to Poison Ivy Contact Dermatitis.

    Smith, Hannah D / Williams, Benjamin / Beck, Lisa A / De Benedetto, Anna

    Dermatitis : contact, atopic, occupational, drug

    2023  Volume 34, Issue 4, Page(s) 336–338

    MeSH term(s) Humans ; Toxicodendron ; Dermatitis, Toxicodendron ; Erythema Multiforme/chemically induced
    Language English
    Publishing date 2023-02-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2144723-8
    ISSN 2162-5220 ; 1532-8163 ; 1710-3568
    ISSN (online) 2162-5220 ; 1532-8163
    ISSN 1710-3568
    DOI 10.1089/derm.2022.0097
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Onychomadesis and palmoplantar keratoderma associated with talquetamab therapy for relapsed and refractory multiple myeloma.

    Narayan, Neha / Williams, Benjamin / Lipe, Brea / De Benedetto, Anna

    JAAD case reports

    2022  Volume 31, Page(s) 66–68

    Language English
    Publishing date 2022-11-17
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834220-3
    ISSN 2352-5126
    ISSN 2352-5126
    DOI 10.1016/j.jdcr.2022.11.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Calcified Urachal Remnant in a Young Adult: An Unusual Case.

    Good, Allison J / Tucker, Duane C / Rudnick, Eric W / De Benedetto, Anna

    Cutis

    2022  Volume 109, Issue 5, Page(s) E30–E31

    MeSH term(s) Humans ; Urachus/pathology ; Young Adult
    Language English
    Publishing date 2022-07-20
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 391840-3
    ISSN 2326-6929 ; 0011-4162 ; 0151-9522
    ISSN (online) 2326-6929
    ISSN 0011-4162 ; 0151-9522
    DOI 10.12788/cutis.0534
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Targetoid clinical morphology as a diagnostic clue of the lichenoid histopathologic subtype of pigmented purpuric dermatosis.

    Ahmed, Amara / Werbel, Tyler / De Benedetto, Anna / Motaparthi, Kiran

    JAAD case reports

    2021  Volume 13, Page(s) 81–85

    Language English
    Publishing date 2021-05-26
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834220-3
    ISSN 2352-5126
    ISSN 2352-5126
    DOI 10.1016/j.jdcr.2021.05.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Skin barrier defects in atopic dermatitis: From old idea to new opportunity.

    Yoshida, Takeshi / Beck, Lisa A / De Benedetto, Anna

    Allergology international : official journal of the Japanese Society of Allergology

    2021  Volume 71, Issue 1, Page(s) 3–13

    Abstract: Atopic dermatitis (AD) is the most common chronic skin inflammatory disease, with a profound impact on patients' quality of life. AD varies considerably in clinical course, age of onset and degree to which it is accompanied by allergic and non-allergic ... ...

    Abstract Atopic dermatitis (AD) is the most common chronic skin inflammatory disease, with a profound impact on patients' quality of life. AD varies considerably in clinical course, age of onset and degree to which it is accompanied by allergic and non-allergic comorbidities. Skin barrier impairment in both lesional and nonlesional skin is now recognized as a critical and often early feature of AD. This may be explained by a number of abnormalities identified within both the stratum corneum and stratum granulosum layers of the epidermis. The goal of this review is to provide an overview of key barrier defects in AD, starting with a historical perspective. We will also highlight some of the commonly used methods to characterize and quantify skin barrier function. There is ample opportunity for further investigative work which we call out throughout this review. These include: quantifying the relative impact of individual epidermal abnormalities and putting this in a more holistic view with physiological measures of barrier function, as well as determining whether these barrier-specific endotypes predict clinical phenotypes (e.g. age of onset, natural history, comorbidities, response to therapies, etc). Mechanistic studies with new (and in development) AD therapies that specifically target immune pathways, Staphylococcus aureus abundance and/or skin barrier will help us understand the dynamic crosstalk between these compartments and their relative importance in AD.
    MeSH term(s) Animals ; Dermatitis, Atopic/immunology ; Disease Progression ; Epidermis/immunology ; Humans ; Quality of Life ; Severity of Illness Index
    Language English
    Publishing date 2021-12-13
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1336498-4
    ISSN 1440-1592 ; 1323-8930
    ISSN (online) 1440-1592
    ISSN 1323-8930
    DOI 10.1016/j.alit.2021.11.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Update on protease-activated receptor 2 in cutaneous barrier, differentiation, tumorigenesis and pigmentation, and its role in related dermatologic diseases.

    Henehan, Mason / De Benedetto, Anna

    Experimental dermatology

    2019  Volume 28, Issue 8, Page(s) 877–885

    Abstract: Protease-activated receptor 2 (PAR2) is a transmembrane receptor expressed by multiple tissues, including skin, with rapidly expanding knowledge regarding its roles. In the skin, PAR2 has extensively documented effects in promoting Th2 inflammation and ... ...

    Abstract Protease-activated receptor 2 (PAR2) is a transmembrane receptor expressed by multiple tissues, including skin, with rapidly expanding knowledge regarding its roles. In the skin, PAR2 has extensively documented effects in promoting Th2 inflammation and pruritus; and its role in atopic dermatitis continues to be thoroughly studied. Numerous new investigations have shown a more complex range of activities potentially related to dermatologic diseases. Goal of this review is to outline emerging effects of PAR2 activation in the skin other than those related to immunologic and pruritic functions. Specifically, this work seeks to summarize current knowledge (and gaps) of PAR2 as a regulator of epidermal barrier, keratinocyte differentiation, cutaneous tumorigenesis and pigmentation. Additional focus will be placed on possible involvement in dermatologic disease and emergence as a therapeutic target.
    MeSH term(s) Animals ; Carcinogenesis ; Cell Differentiation ; Extracellular Matrix/metabolism ; Humans ; Keratinocytes/physiology ; Paracrine Communication ; Phagocytosis ; Receptor, PAR-2/metabolism ; Skin Diseases/metabolism ; Skin Pigmentation ; Tight Junction Proteins/metabolism
    Chemical Substances Receptor, PAR-2 ; Tight Junction Proteins
    Language English
    Publishing date 2019-05-15
    Publishing country Denmark
    Document type Journal Article ; Review
    ZDB-ID 1130936-2
    ISSN 1600-0625 ; 0906-6705
    ISSN (online) 1600-0625
    ISSN 0906-6705
    DOI 10.1111/exd.13936
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Legionella pneumophila

    Lupia, Tommaso / Corcione, Silvia / Shbaklo, Nour / Rizzello, Barbara / De Benedetto, Ilaria / Concialdi, Erika / Navazio, Anna Sara / Penna, Maurizio / Brusa, Maria Teresa / De Rosa, Francesco Giuseppe

    Microorganisms

    2023  Volume 11, Issue 2

    Abstract: Legionella ... ...

    Abstract Legionella pneumophila
    Language English
    Publishing date 2023-02-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11020498
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Isotretinoin-induced inflammation of the urethral meatus.

    Della Porta, Adriana L / Saikaly, Sami K / Nyinawinyange, Domina / De Benedetto, Anna

    Dermatologic therapy

    2021  Volume 34, Issue 2, Page(s) e14898

    MeSH term(s) Female ; Humans ; Inflammation/chemically induced ; Isotretinoin/adverse effects ; Male ; Urethra ; Vulva
    Chemical Substances Isotretinoin (EH28UP18IF)
    Language English
    Publishing date 2021-02-28
    Publishing country United States
    Document type Letter
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.14898
    Database MEDical Literature Analysis and Retrieval System OnLINE

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